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M. avium 104 MAV_1835 (-)

annotation: acyl-CoA dehydrogenase protein
coordinates: 1830508 - 1831653
length: 381

PVASERTEDTAALRSRIQTFLENAPKPAGLRNYGPTPTAADVEPGRTWHKYLAEHGYVCLHWPVEYGGAD
ASVAFQAIFAEECARAGVPRQLGITAIDLVGPVLIKFGTDEQKARYLEPIRLGDDIWTQLFSEPGAGSDL
ASVRTKAEKTETGWRINGQKVWSSAAKSAKYGLLLARTGPHKHRDLSVFVLPMDTPGVSVRPLTQMDGES
KFNEVFFDGVEIRDDALIGEVGQGWTIAIMTLGRERLTLGSQAVAMFRLHERMVEAAREHDLLDPVLARS
MTKLWARMWLLRFTWQRAIDSGDTSSAAFSVLKLMTSETDRDLGDMATEVLGTDACADPGDEELVQHMLV
GRAQTILGGTSEIQRNILGERVLGLPKEPR*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_1835 - - 100% (381) acyl-CoA dehydrogenase protein
M. avium 104 MAV_2570 - 0.0 80.53% (380) putative acyl-CoA dehydrogenase
M. avium 104 MAV_0601 - 1e-64 38.85% (381) putative acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3590c fadE30 2e-66 39.58% (384) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCK Mflv_1481 - 4e-64 39.83% (354) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3560c fadE30 2e-66 39.58% (384) acyl-CoA dehydrogenase FADE30
M. leprae Br4923 MLBr_00737 fadE25 2e-23 33.33% (228) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0597 - 3e-68 41.24% (354) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_5049 fadE30 2e-65 40.79% (353) acyl-CoA dehydrogenase FadE30
M. smegmatis MC2 155 MSMEG_6012 - 6e-63 40.06% (362) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4597 - 0.0 82.54% (378) PUTATIVE acyl-CoA dehydrogenase protein
M. ulcerans Agy99 MUL_4125 fadE30 6e-65 40.51% (353) acyl-CoA dehydrogenase FadE30
M. vanbaalenii PYR-1 Mvan_5285 - 2e-66 41.18% (357) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MAV_1835|M.avium_104                --------MPVASERTED-TAALRSRIQTFLEN--APKPAGLRNYG-PTP
TH_4597|M.thermoresistible__bu      -----VTITDNGPASTDS-LGDLRAKFRDFLAD--APKPAGLRNYG-PTP
Mflv_1481|M.gilvum_PYR-GCK          --------------MIEV--QKFRAEVRDWLAENLVGDFAALKGLGGPGR
Mvan_5285|M.vanbaalenii_PYR-1       --------------MIEV--QEFRAEVRDWLAENLVGEYAALKGLGGPGR
MSMEG_6012|M.smegmatis_MC2_155      --------------MIEV--QEFRAEVRQWLADNLVGDFAALKGLGGPGR
Mb3590c|M.bovis_AF2122/97           --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
Rv3560c|M.tuberculosis_H37Rv        --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
MMAR_5049|M.marinum_M               --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MUL_4125|M.ulcerans_Agy99           --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MLBr_00737|M.leprae_Br4923          -MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPE
                                                          .*: .:       . . * :   .    

MAV_1835|M.avium_104                TAADVEPGRTWHKYLAEHGYVCLHWPVEYGGADASVAFQAIFAEECARAG
TH_4597|M.thermoresistible__bu      TADDIEPGRAWHKYLADHGYVCLHWPREYGGADAPVAFQAAFAEECARAG
Mflv_1481|M.gilvum_PYR-GCK          EHEAFEERLAWNQHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
Mvan_5285|M.vanbaalenii_PYR-1       EHEAFEERLAWNRHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
MSMEG_6012|M.smegmatis_MC2_155      EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYARAN
Mb3590c|M.bovis_AF2122/97           EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
Rv3560c|M.tuberculosis_H37Rv        EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
MMAR_5049|M.marinum_M               EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MUL_4125|M.ulcerans_Agy99           EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
MLBr_00737|M.leprae_Br4923          EALAA---------LNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                                  *   *  .:  * *:** .        . ** *:. 

MAV_1835|M.avium_104                VPRQLGITAIDLVGPVLIKFGTDEQKARYLEPIRLGDDIWTQLFSEPGAG
TH_4597|M.thermoresistible__bu      VPRQLAITAIDLVGPVLIKFGTDEQKARYLEPIRLGDHVWTQLFSEPGAG
Mflv_1481|M.gilvum_PYR-GCK          APDKVNHLGEELLGPTLIAYGTPEQQQRFLPRILDVTELWSQGYSEPGAG
Mvan_5285|M.vanbaalenii_PYR-1       APDKVNHLGEELLGPTLIAYGTPEQQQRFLPKILDVTELWSQGYSEPGAG
MSMEG_6012|M.smegmatis_MC2_155      APDKVNHFGEELLGPTLIEYGTPEQQKRFLPKILDVTELWCQGYSEPNAG
Mb3590c|M.bovis_AF2122/97           APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
Rv3560c|M.tuberculosis_H37Rv        APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
MMAR_5049|M.marinum_M               APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
MUL_4125|M.ulcerans_Agy99           APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
MAB_0597|M.abscessus_ATCC_1997      APHKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPGAG
MLBr_00737|M.leprae_Br4923          ASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAG
                                    .. .:     .*    **  *: : : : *  :     :     **  **

MAV_1835|M.avium_104                SDLASVRTKAEKT----------ETGWRINGQKVWSSAAKSAKYGLLLAR
TH_4597|M.thermoresistible__bu      SDLAGVRTRAEKT----------DTGWRINGQKVWSSAANSADYGLLLAR
Mflv_1481|M.gilvum_PYR-GCK          SDLANVSTTATLD----------GDEWVINGQKVWTSLAHWAQWCFVVAR
Mvan_5285|M.vanbaalenii_PYR-1       SDLANVSTTAVLDE--------EGRQWHINGQKVWTSLAHWAQWCFVVAR
MSMEG_6012|M.smegmatis_MC2_155      SDLANVSTTAELVGDAEASGATGNQYWVINGQKVWTSLAHWAQWCFVVAR
Mb3590c|M.bovis_AF2122/97           SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
Rv3560c|M.tuberculosis_H37Rv        SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
MMAR_5049|M.marinum_M               SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
MUL_4125|M.ulcerans_Agy99           SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
MAB_0597|M.abscessus_ATCC_1997      SDLANVSTSAVLD----------GGDWVINGQKVWTSLALQSQWCFVVAR
MLBr_00737|M.leprae_Br4923          SDAASMRTRAKAD----------GDDWILNGFKCWITNGGKSTWYTVMAV
                                    ** *.: * *                * :** * * : .  : :  ::* 

MAV_1835|M.avium_104                T--GPHKHRDLSVFVLPMDTPGVSVRPLTQMDGE--SKFNEVFFDGVEIR
TH_4597|M.thermoresistible__bu      T--GPDSHRGLSMFIVPMDADGVSVRPLKQMDGE--SKFNEVFLDNVELP
Mflv_1481|M.gilvum_PYR-GCK          TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTA
Mvan_5285|M.vanbaalenii_PYR-1       TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTD
MSMEG_6012|M.smegmatis_MC2_155      TEKGSKRHAGLSYLLVPLDQPGVEIRPINQLTGD--SEFNEVFFDDARTE
Mb3590c|M.bovis_AF2122/97           TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
Rv3560c|M.tuberculosis_H37Rv        TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
MMAR_5049|M.marinum_M               TEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
MUL_4125|M.ulcerans_Agy99           TEKGSKRHAGLSYLLVPLDQPSVQIRPIVQITGT--AEFNEVFFDDARTD
MAB_0597|M.abscessus_ATCC_1997      TEPGSSRHKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTS
MLBr_00737|M.leprae_Br4923          TD-PDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIP
                                    *        .:* :::  :  ...: *  :  *   :  .*:::*  .  

MAV_1835|M.avium_104                DDALIGEVGQGWTIAIMTLGRER--LTLGSQAVAMFRLHERMVEAAREHD
TH_4597|M.thermoresistible__bu      DDAIIGEPGQGWTIAIMTLGRER--LTLGSQAVAMFKLHEKLVAAARDRG
Mflv_1481|M.gilvum_PYR-GCK          ADLVVGEPGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAEKTGA
Mvan_5285|M.vanbaalenii_PYR-1       ADLVVGEPGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAKRTGA
MSMEG_6012|M.smegmatis_MC2_155      AGLVVGQPGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAKRTGA
Mb3590c|M.bovis_AF2122/97           ADLVVGAPGDGWRVAMATLTFERGVSTLGQQIVYARELSNLVELARRTAA
Rv3560c|M.tuberculosis_H37Rv        ADLVVGAPGDGWRVAMATLTFERGVSTLGQQIVYARELSNLVELARRTAA
MMAR_5049|M.marinum_M               ADLVVGAPGDGWRVAMGTLTFERGVSTLGQQIVYARELSDLAALARRTGA
MUL_4125|M.ulcerans_Agy99           ADLVVGAPGDGWRVAMGTLTFERGVSTLGQQIVYARELSDLAALARRTGA
MAB_0597|M.abscessus_ATCC_1997      ADLVVGEPGDGWRVAMGTLTFERGVSTLGNQITYARELSRLAELAKSNGA
MLBr_00737|M.leprae_Br4923          GDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQ
                                     . ::*  * *:  *: **   *                     :     

MAV_1835|M.avium_104                LLDPVLARSMTKLWARMWLLRFTWQRAID-SGDTSSAA-FSVLKLMTSET
TH_4597|M.thermoresistible__bu      ALDPVLARSMTRLWARMWLLRYTWQRAID-EGDTTSAA-FSVLKLMTSET
Mflv_1481|M.gilvum_PYR-GCK          ADDPLIRERLVRSWAGLKAMRSYALATMD---VEKPGQ-DNISKLLWANW
Mvan_5285|M.vanbaalenii_PYR-1       ADDPLIRERLTRSWAGLKAMRSYALATMD---VEQPGM-DNVSKLLWANW
MSMEG_6012|M.smegmatis_MC2_155      ADDPLIRERLVQSWTGLQAMRSYALATMD---VEQPGQ-DNVSKLLWANW
Mb3590c|M.bovis_AF2122/97           ADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQ-DNVSKLLWANW
Rv3560c|M.tuberculosis_H37Rv        ADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQ-DNVSKLLWANW
MMAR_5049|M.marinum_M               ADDPFIRERLTRAWTGLRAMRSYALATMD---VEQPGQ-DNVSKLLWANW
MUL_4125|M.ulcerans_Agy99           ADDPFIREHLTRAWTGLRAMRSYALATMD---VEQPGQ-DNVSKLLWANW
MAB_0597|M.abscessus_ATCC_1997      ADDPAIRERLAQAYVGMRTMRAYALATMD---EERPGQ-DNVSKLLWANW
MLBr_00737|M.leprae_Br4923          FGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAAS
                                      :.       :       ::      :       .        :: :  

MAV_1835|M.avium_104                DRDLGDMATEVLGTDACADP-----GDEELVQHMLVGRAQTILGGTSEIQ
TH_4597|M.thermoresistible__bu      DRDLADMATEVLGTDVCVDPTAGT-DDADLVRAMLVGRAQTILGGTSEIQ
Mflv_1481|M.gilvum_PYR-GCK          HRELGEIAMDIEGAAGLTLPDG---EFSEWQRLYLFSRSDTIYGGSNEIQ
Mvan_5285|M.vanbaalenii_PYR-1       HRELGEIAMDVQGMAGLTLPGG---EFDEWQRLYLFSRSDTIYGGSNEIQ
MSMEG_6012|M.smegmatis_MC2_155      HRELGEIAMDVQGMAGLTLENG---EFDEWQRLYLFSRADTIYGGSNEIQ
Mb3590c|M.bovis_AF2122/97           HRNLGELAMDVIGKPGMTMPDG---EFDEWQRLYLFTRADTIYGGSNEIQ
Rv3560c|M.tuberculosis_H37Rv        HRNLGELAMDVIGKPGMTMPDG---EFDEWQRLYLFTRADTIYGGSNEIQ
MMAR_5049|M.marinum_M               HRSLGELAMDVIGKPGLTLADG---EFDEWQRLFLFTRADTIYGGSNEIQ
MUL_4125|M.ulcerans_Agy99           HRSLGELAMDVIGKPGLTLADG---EFDEWQRLFLFTRADTIYGGSNEIQ
MAB_0597|M.abscessus_ATCC_1997      HRDLGELAMEIIGTSTLLTNAG---EMDEWQRLFLFSRADTIYGGSNEIQ
MLBr_00737|M.leprae_Br4923          KCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQ
                                    .   .::* ::                    :     :   *  *:.:**

MAV_1835|M.avium_104                RNILGERVLGLPKEPR-
TH_4597|M.thermoresistible__bu      RNILGERVLGLPKEPR-
Mflv_1481|M.gilvum_PYR-GCK          RNIIAERVLGLPREARH
Mvan_5285|M.vanbaalenii_PYR-1       RNIIAERVLGLPREAKG
MSMEG_6012|M.smegmatis_MC2_155      RNIIAERVLGLPREVKG
Mb3590c|M.bovis_AF2122/97           RNIIAERVLGLPREAKG
Rv3560c|M.tuberculosis_H37Rv        RNIIAERVLGLPREAKG
MMAR_5049|M.marinum_M               RNIIAERVLGLPREAKG
MUL_4125|M.ulcerans_Agy99           RNIIAERVLGLPREAKG
MAB_0597|M.abscessus_ATCC_1997      RNIISERVLGLPREAR-
MLBr_00737|M.leprae_Br4923          RVVMSRALLR-------
                                    * ::.. :*

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_1835	-	-	100% (381)	acyl-CoA dehydrogenase protein
M. avium 104	MAV_2570	-	0.0	80.53% (380)	putative acyl-CoA dehydrogenase
M. avium 104	MAV_0601	-	1e-64	38.85% (381)	putative acyl-CoA dehydrogenase