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LDQASAEGLSLTVALERLLAVEVEASTARRLAGRLRFACLPTPATLADFDVDAAAGIDRKLIDELGTCRY LESATNILLIGPPGTGKTHLSVGLARAAAHAGYRTYFTTAADLAARCHRAAIEGRWATTMRFYAGQDLTR SLDFYATFPFPKPTLSKWLRGDYANLTAVIDLTLSRLDAGLFTGTFLEGELTELELQWGRTIGQMPSPYT ARNPLVVPYHFNQGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1806 | - | - | 100% (225) | LprM protein |
| M. avium 104 | MAV_2536 | - | 1e-34 | 73.20% (97) | virulence factor Mce family protein |
| M. avium 104 | MAV_2068 | - | 2e-30 | 65.91% (88) | LprM protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0179 | lprK | 2e-07 | 41.27% (63) | MCE-family lipoprotein LprK |
| M. gilvum PYR-GCK | Mflv_0693 | - | 7e-40 | 98.78% (82) | putative transposition helper protein |
| M. tuberculosis H37Rv | Rv1970 | lprM | 6e-28 | 60.20% (98) | MCE-family lipoprotein LprM |
| M. leprae Br4923 | MLBr_02593 | lprK | 2e-07 | 42.59% (54) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_4149c | - | 1e-05 | 45.10% (51) | MCE-family protein LprN |
| M. marinum M | MMAR_4055 | lprM_1 | 5e-37 | 72.83% (92) | MCE family lipoprotein LprM |
| M. smegmatis MC2 155 | MSMEG_2150 | - | 1e-71 | 87.82% (156) | putative transposition helper protein |
| M. thermoresistible (build 8) | TH_1648 | - | 1e-72 | 88.46% (156) | putative transposition helper protein |
| M. ulcerans Agy99 | MUL_3922 | lprM_1 | 3e-37 | 72.83% (92) | MCE family lipoprotein LprM |
| M. vanbaalenii PYR-1 | Mvan_0517 | - | 8e-37 | 72.83% (92) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4055|M.marinum_M --------MMWARWTTRIRIAAGIAALAVAVSGCS--GWRGLNSLPLPGV
MUL_3922|M.ulcerans_Agy99 ---------MRAGWTTRIRIAAGIAALAVAVSGCS--GWRGLNSLPLPGV
Rv1970|M.tuberculosis_H37Rv -----------------MRIGLTLVMIAAVVASC---GWRGLNSLPLPGT
Mvan_0517|M.vanbaalenii_PYR-1 ---------MTG---KRFARAAAVIMIALTVAGLSGCGFRGLNSFRLPGT
Mb0179|M.bovis_AF2122/97 ---MMSVLARMRVMRHRAWQGLVLLVLALLLSSCG---WRGISNVAIPGG
MLBr_02593|M.leprae_Br4923 MRRAMSVVHTSRVR-HQTWRGLVMLVAALLLSSCG---WRGISNVSIPGG
MAB_4149c|M.abscessus_ATCC_199 ------------MSRNVLRAAVMGVGVAVVVSGCQ---FNGLNSLNLPGT
MSMEG_2150|M.smegmatis_MC2_155 --------------------------------------------------
TH_1648|M.thermoresistible__bu --------------------------------------------------
Mflv_0693|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1806|M.avium_104 --------------------------------------------------
MMAR_4055|M.marinum_M QGGGPGSFTIQAQMPDVDNIEPNSRVRVGDVNVGTVTKIERQG-----WH
MUL_3922|M.ulcerans_Agy99 QGGGPGSFTIQAQMPDVDNIEPNSRVRVGDVNVGTVTKIERQG-----WH
Rv1970|M.tuberculosis_H37Rv QGNGPGSFAVQAQLPDVNNIQPNSRVRVADVTVGHVTKIERQG-----WH
Mvan_0517|M.vanbaalenii_PYR-1 QGQGQGSYTIQAEMPDVETLQPNSRVRVGDVNVGTVTKIERRG-----WH
Mb0179|M.bovis_AF2122/97 PGTGPGSYTIYVQMPDTLAINGNSRVMVADVWVGSIRAIKLKN-----WV
MLBr_02593|M.leprae_Br4923 PGSGKGAYTIYVQVPDTLAINGNSKVMVADVTVGSIRAINLKN-----WV
MAB_4149c|M.abscessus_ATCC_199 AGHGSRSYTVTVELPDVTTLPQNSPVMVDDVTVGSVSGIDAFQKPDGSWY
MSMEG_2150|M.smegmatis_MC2_155 ------------MTPTPRTAKN-TATVTEEPPSTAASRYQKLR------S
TH_1648|M.thermoresistible__bu ------------MTPTPRTPKTATTTTVEESPSAAASRYQQLR------S
Mflv_0693|M.gilvum_PYR-GCK ------------MTPTPRTKKT--TTTTDETPSTSASRYQQLR------S
MAV_1806|M.avium_104 --------------------------------------------------
MMAR_4055|M.marinum_M ALVTMKLNGNVELPANATATLGQTSLLGSLHIELAPPTDVPPEGNLREGS
MUL_3922|M.ulcerans_Agy99 ALVTMKLNGNVELPANATATLGQTSLLGSLHIELAPPTDVPPEGNLREGS
Rv1970|M.tuberculosis_H37Rv ALVTMRLDGDVDLPANATAKIGTTSLLGSYHIELAPPKGEARQGKLRDGS
Mvan_0517|M.vanbaalenii_PYR-1 ALLTLALNGDVDLPANSTVSLGQTSLLGSLHIELAPPTDVRPAGKLRAGS
Mb0179|M.bovis_AF2122/97 ATLTLSLKKDVTLPKNATAKIGQTSLLGSQHVELAAPP-DPSPVPLKDGD
MLBr_02593|M.leprae_Br4923 ATLTLGLNKDVQLPKNTTAKIGQTSLLGSQHVELAAPA-NPSLELLKNGD
MAB_4149c|M.abscessus_ATCC_199 AGVKVSLEPEVHLPANAVAKVAQTSLLGSQHIELAAPVGEPAVGKLTGGA
MSMEG_2150|M.smegmatis_MC2_155 HLAELKLHAAAAALPAVLDQASAENLS----------------------L
TH_1648|M.thermoresistible__bu HLAELKLAAAAEALPAVLDEATAEGLS----------------------L
Mflv_0693|M.gilvum_PYR-GCK HLAALNLHACAEALPAVLDQASAEGLS----------------------L
MAV_1806|M.avium_104 -----------------MDQASAEGLS----------------------L
.*
MMAR_4055|M.marinum_M LIPLSSSKAYPSTEQALAATAMLLNGGGIGDIYDITEALSTAFTGRENDL
MUL_3922|M.ulcerans_Agy99 LIPLSSSKAYPSTEQALAATAMLLNGGGIGDIYDITEALSTAFTGRENDL
Rv1970|M.tuberculosis_H37Rv LIALSHGSAYPSTEQTLAALSLVLNGGGLGQVQDITEALSTAFAGREHDL
Mvan_0517|M.vanbaalenii_PYR-1 LIPLTSAGAYPSTEQTLASVSLLLNGGGVGQVQDITTALTSALGGREADF
Mb0179|M.bovis_AF2122/97 TIPLKRSSAYPTTEQTLASIATLLRGGGLVNLEGIQQEINAIVTGRADQI
MLBr_02593|M.leprae_Br4923 TIPLKNSSVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQI
MAB_4149c|M.abscessus_ATCC_199 TIPLSRTGKYPSTEEVLSALSVVVNKGNLGALQDITDETYNLFKGRTGNL
MSMEG_2150|M.smegmatis_MC2_155 TVALERLLAVEVEASTARRLAGRLRFACLPTPATLDDFDVDAAAGIDRKL
TH_1648|M.thermoresistible__bu TVALERLLAVEVEASTARRLAGRLRFACLPTPATLADFDVDAAAGIDRKL
Mflv_0693|M.gilvum_PYR-GCK TVALERLLAVEVEASTARRLAGRLRFACIPTPATLADFDVDAAAGIDRKL
MAV_1806|M.avium_104 TVALERLLAVEVEASTARRLAGRLRFACLPTPATLADFDVDAAAGIDRKL
:.* .. : :. . : : * .:
MMAR_4055|M.marinum_M RSLIEQLDEAIGHLDDQKGDIIAAAESLNNLMAQLAAQRPVLDKALRTIP
MUL_3922|M.ulcerans_Agy99 RSLIEQLDEAIGHLDDQKGDIIAAAESLNNLMAQLAAQRPVLDKALRTIP
Rv1970|M.tuberculosis_H37Rv RGLIGQLDTFTAYLNNQSGDIIAATDSLNRLVGKFADQQPVFDRALATIP
Mvan_0517|M.vanbaalenii_PYR-1 RSLLTQLDTFTANVNGQIGDIIAATDSLNNLVAQFAAQKPIIDKALETIP
Mb0179|M.bovis_AF2122/97 RAFLGKLDTFTDELNQQRDDITRAIDSTNRLLAYVGGRSEVLNRVLTDLP
MLBr_02593|M.leprae_Br4923 HAFLTKLDTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILTDIP
MAB_4149c|M.abscessus_ATCC_199 TQVLPKLATLISSLNSQRDDIISAIEGIDKFSRVLAEHKESLGRAIDSIE
MSMEG_2150|M.smegmatis_MC2_155 IDELGTCRYLESATN------------------------------ILLVG
TH_1648|M.thermoresistible__bu IDELGTCRYLESATN------------------------------ILLIG
Mflv_0693|M.gilvum_PYR-GCK IDELGTCRYLESATN------------------------------ILLIG
MAV_1806|M.avium_104 IDELGTCRYLESATN------------------------------ILLIG
: : : :
MMAR_4055|M.marinum_M DALAVLKNERENLADALTQLGRFSALAADSVNQTKDALVQELKDLGPTLE
MUL_3922|M.ulcerans_Agy99 DALTVLKNERENLADALTQLGRFSALAADSVNQTKDALVQELKDLGPTLE
Rv1970|M.tuberculosis_H37Rv DALAVLADERDTLVEAAEQLSKFSALTVDSVNKTTANLVTELRQLGPVLE
Mvan_0517|M.vanbaalenii_PYR-1 DALAVINAERDQLVEAVDQLGKFSALAADTVNQSQESLIQILNDMGPVLE
Mb0179|M.bovis_AF2122/97 PLIKHFADKQELLINASDAVGRLSQSADQYLSAARGDLHQDLQALQCPLK
MLBr_02593|M.leprae_Br4923 PLIKHFADTKNLLINAVGSVGQLSQAVDQYLSEARGPLHTDLQALACPLR
MAB_4149c|M.abscessus_ATCC_199 PALKVLNENRANIIEAFRSVGNLAKITDRVLRTTKDDIVADLKGLYPVVR
MSMEG_2150|M.smegmatis_MC2_155 PPGTGKTHLSVGLARAAAHAGYRTYFTTAADLAARCHRAAIEGRWATTMR
TH_1648|M.thermoresistible__bu PPGTGKTHLSVGLARAAAHAGYRTYFTTAADLAARCHRAAIEGRWATTMR
Mflv_0693|M.gilvum_PYR-GCK P-------------------------------------GVIEG-------
MAV_1806|M.avium_104 PPGTGKTHLSVGLARAAAHAGYRTYFTTAADLAARCHRAAIEGRWATTMR
MMAR_4055|M.marinum_M SLANAGPALTRALSFLPTYPFPKETLTNWMRGDYANLTLIIDMTLSRIDA
MUL_3922|M.ulcerans_Agy99 SLANAGPALTRALSFLPTYPFPKETLTNWMRGDYANLTLIIDMTLSRIDA
Rv1970|M.tuberculosis_H37Rv SLANSGPALTRSLSLLATFPFPNETFQNFQRGEYANLTAIVDLTLSRIDQ
Mvan_0517|M.vanbaalenii_PYR-1 SLANAGPALTRSLNLFTTIPFVKDNLTKWWRGDYANITTIVDLTLSRIDA
Mb0179|M.bovis_AF2122/97 ELRRAAPYLVGALKLILTQPFDVDTVPQLVRGDYMNLSLTLDLTYSAIDN
MLBr_02593|M.leprae_Br4923 ELGRGAPYFIGAMKLILTQPYDVDTVPKIMRGDYQNVSLTLDVTYSAMDN
MAB_4149c|M.abscessus_ATCC_199 ALAENRDVLIDSLDLLPTFPFSTKYLRNAVRGDYLNVFVTFDLTARRLGE
MSMEG_2150|M.smegmatis_MC2_155 FYA--GPTLLVIDELGYLPLPAEAASALFQVVSQRYLKTSIVITTNRGVG
TH_1648|M.thermoresistible__bu FYA--GPTLLVIDELGYLPLPAEAASALFQVVSQRYLKTSIVITTNRGVG
Mflv_0693|M.gilvum_PYR-GCK ----------------------SNAERPCYACSGR--------CCDR---
MAV_1806|M.avium_104 FYA--GQDLTRSLDFYATFPFPKPTLSKWLRGDYANLTAVIDLTLSRLDA
.
MMAR_4055|M.marinum_M G---FFTGTRWEGDLTELELQWGRTIGQMPSPYTVG------NPLIVPYR
MUL_3922|M.ulcerans_Agy99 G---FFTGTRWEGDLTELELQWGRTIGQMPSPYTVG------NPLIVPYR
Rv1970|M.tuberculosis_H37Rv G---LLTGTRWECHLTQLELQWGRTIGQFPSPCTAGYRGTPGNPLTIAYR
Mvan_0517|M.vanbaalenii_PYR-1 G---LFTGTRFEGHLTELELQWGRTIGQLPSPYTAR------NPLIVPYR
Mb0179|M.bovis_AF2122/97 A---FLTGTGFSGALRALEQSFGRDPETMIPDIR-----YTPNPNDAPGG
MLBr_02593|M.leprae_Br4923 A---VLTGTGLSGALRALEQSFGRDPETMIPDVR-----YTTNPNDAPGG
MAB_4149c|M.abscessus_ATCC_199 T---LFTTSFFDPNMQHFNDVVN-PPEWLIGSMANL-NGKETSPFDLPAP
MSMEG_2150|M.smegmatis_MC2_155 SWGEILGDTTVAAAMLDRLLHRSVVINLDGESYRLRDHQAAAETLRRATT
TH_1648|M.thermoresistible__bu AWGEILGDTTVAAAMLDRLLHRSVVINLDGESYRLRDHQAAAETLRRTTT
Mflv_0693|M.gilvum_PYR-GCK --------------------------------YDVR--------------
MAV_1806|M.avium_104 G---LFTGTFLEGELTELELQWGRTIGQMPSPYTARNPLVVPYHFNQGP-
MMAR_4055|M.marinum_M --WDQGP---
MUL_3922|M.ulcerans_Agy99 --WDQGP---
Rv1970|M.tuberculosis_H37Rv --WDQGP---
Mvan_0517|M.vanbaalenii_PYR-1 --LDQGP---
Mb0179|M.bovis_AF2122/97 PLVERGNRQC
MLBr_02593|M.leprae_Br4923 PLVERADRRC
MAB_4149c|M.abscessus_ATCC_199 AAPQGGGR--
MSMEG_2150|M.smegmatis_MC2_155 GTRQALH---
TH_1648|M.thermoresistible__bu GTRQPLH---
Mflv_0693|M.gilvum_PYR-GCK ----------
MAV_1806|M.avium_104 ----------