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MRGADFVLPTDVPEAGRPLRIVLVAPPYFDVPPDGYGGVEAVVADLADMLVARGHQVTLLGAGEPGTAAR FIPLWDRTVPERLGEPYPEIMHALKVRSAITRIAKEDGVDIVHDHTFAGPMNAPIYQGLGVPTVVTVHGP IDDDLHPYYRELSGDVGLVAISDRQRQLAPELNWVGRVHNALRIDEWPFETEKHDYALFLGRYAPYKGAH LALRAAHEAGIPLVLAGKCSEPSEKEYFEDCVRPLLTDNDHVFGEADAVSKRKLLSRARCLLFPIQWEEP FGIVMIEAMVCGTPVVALRGGAVSEVVADGVTGVVCDHPDELPGAIARAQTLDPHACRRHVAANFAVAQF GSAYEAIYRNVLQHATAAPRRMRSTGLVESIETGRRACDFRQKAPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1024 | - | - | 100% (396) | glycosyl transferase, group 1 family protein |
| M. avium 104 | MAV_3486 | - | 1e-16 | 28.10% (363) | phosphatidylinositol alpha-mannosyltransferase |
| M. avium 104 | MAV_3879 | - | 2e-15 | 26.84% (380) | glycosyl transferase, group 1 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1244c | - | 2e-16 | 28.64% (405) | putative glycosyl transferase |
| M. gilvum PYR-GCK | Mflv_0483 | - | 5e-32 | 30.05% (396) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv1212c | - | 1e-16 | 28.89% (405) | putative glycosyl transferase |
| M. leprae Br4923 | MLBr_00452 | - | 8e-17 | 26.50% (351) | putative glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_1014c | - | 1e-14 | 31.60% (250) | glycosyl transferase |
| M. marinum M | MMAR_2092 | pimA | 1e-17 | 27.04% (355) | alpha-mannosyltransferase PimA |
| M. smegmatis MC2 155 | MSMEG_5641 | - | 1e-167 | 75.82% (364) | glycosyl transferase, group 1 family protein |
| M. thermoresistible (build 8) | TH_0092 | - | 1e-159 | 70.74% (376) | glycosyl transferase, group 1 family protein |
| M. ulcerans Agy99 | MUL_3252 | pimA | 3e-18 | 27.30% (359) | alpha-mannosyltransferase PimA |
| M. vanbaalenii PYR-1 | Mvan_2096 | - | 3e-14 | 27.11% (402) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5641|M.smegmatis_MC2_155 MSGN------------------------DILAPADVDD---PLRIVLVAP
TH_0092|M.thermoresistible__bu MSGNGFRFHHTFRDQNATAADTAPADTAALLSETESTD---PLRIVLVAP
MAV_1024|M.avium_104 MRGA------------------------DFVLPTDVPEAGRPLRIVLVAP
MMAR_2092|M.marinum_M ------------------------------------------MRIGMVCP
MUL_3252|M.ulcerans_Agy99 ------------------MAHVSATMVGRLVRCPPRAAAGALMRIGMVCP
MLBr_00452|M.leprae_Br4923 ------------------------------------------MRIGMICP
Mb1244c|M.bovis_AF2122/97 ------------------------------------------MRVAMLTR
Rv1212c|M.tuberculosis_H37Rv ------------------------------------------MRVAMLTR
Mflv_0483|M.gilvum_PYR-GCK ------------------------------------------MRVALIAP
Mvan_2096|M.vanbaalenii_PYR-1 ------------------------------------------MKTKILLV
MAB_1014c|M.abscessus_ATCC_199 ------------------------------------------MSTSRVAI
: :
MSMEG_5641|M.smegmatis_MC2_155 PYFDIPPKGYGGTEAVVADLADTLTARGHHVTVLGAGAPGTAAR------
TH_0092|M.thermoresistible__bu PYFDIPPKAYGGTEAVVADLADSLTARGHRVTVLGAGNPRIAAR------
MAV_1024|M.avium_104 PYFDVPPDGYGGVEAVVADLADMLVARGHQVTLLGAGEPGTAAR------
MMAR_2092|M.marinum_M YSFDVA----GGVQSHVLQLAEVMRARGHEVSVLAPASPHAALPD-----
MUL_3252|M.ulcerans_Agy99 YSFDVA----GGVQSHVLQLAEVMRARGHEVSVLAPASPHAALPD-----
MLBr_00452|M.leprae_Br4923 YSFDVP----GGVQSHVLQLAEVMRARGQQVRVLAPASPDVSLPE-----
Mb1244c|M.bovis_AF2122/97 ---EYPPEVYGGAGVHVTELVAYLR-RLCAVDVHCMGAPRPGAFA-----
Rv1212c|M.tuberculosis_H37Rv ---EYPPEVYGGAGVHVTELVAYLR-RLCAVDVHCMGAPRPGAFA-----
Mflv_0483|M.gilvum_PYR-GCK HHFPIREPFAGGIESHVWHLARALIRQGHAVTLCAAAGSDLAMEHP----
Mvan_2096|M.vanbaalenii_PYR-1 S-WEYPPVVIGGLGRHVHHLATELAQSGHEVVVLSRRPTATDPQTHPTTD
MAB_1014c|M.abscessus_ATCC_199 VHERFT--EFGGSELVVAEFMKTWPQAKVFAPITEPHCRRQVMHAAG---
** * .: . :
MSMEG_5641|M.smegmatis_MC2_155 -------FQPLWERTLPDRLGQPYPEIMHALKVRKAIERIAATEG-VDIV
TH_0092|M.thermoresistible__bu -------FVPLWERTIPDRLGQPYPEVMHALKVRRAIADIADREGGIDLI
MAV_1024|M.avium_104 -------FIPLWDRTVPERLGEPYPEIMHALKVRSAITRIAKEDG-VDIV
MMAR_2092|M.marinum_M -------YVVSGGKAVPIPYNGSVARLRFGPATHRKVKKWLSEGD-FDVL
MUL_3252|M.ulcerans_Agy99 -------YVVSGGKAVPIPYNGSVARLRFGPATHRKVKKWLSEGD-FDVL
MLBr_00452|M.leprae_Br4923 -------YVVSAGRAIPIPYNGSVARLQFSPAVHSRVRRWLVDGD-FDVL
Mb1244c|M.bovis_AF2122/97 -------YRPD----------PRLGSANAALSTLSADLVMANAASAATVV
Rv1212c|M.tuberculosis_H37Rv -------YRPD----------PRLGSANAALSTLSADLVMANAASAATVV
Mflv_0483|M.gilvum_PYR-GCK --ALTVTAMPRSAAASRVFPPPGAIKESAHHAFVELMSELADPASGVDVV
Mvan_2096|M.vanbaalenii_PYR-1 EVHEGVRVIAAAEDPHEFTFGTDMMAWTLAMGHAMIRAGLVLADWRPDIV
MAB_1014c|M.abscessus_ATCC_199 ---RTEGAPHEPISGTWLDDAYALTGRRSHAPLLPLVPGALGKLPLGDDV
:
MSMEG_5641|M.smegmatis_MC2_155 HDHTFAGP-LNAPFYRKLGLPTVVTVHG--------------PIDEDLYP
TH_0092|M.thermoresistible__bu HDHTFAGP-LNVPAYRELGVPTVATVHG--------------PIDEDLYP
MAV_1024|M.avium_104 HDHTFAGP-MNAPIYQGLGVPTVVTVHG--------------PIDDDLHP
MMAR_2092|M.marinum_M HLHEPNAPSLSMLALNIAEGPIVATFHTST-----TKSLTLTVFQSILRP
MUL_3252|M.ulcerans_Agy99 HLHEPNAPSLSMLALNIAEGPIVATFHTST-----TKSLTLTVFQSILRP
MLBr_00452|M.leprae_Br4923 HLHEPNAPSLSMWALRVAEGPIVATFHTST-----TKSLTLSVFQGVLRP
Mb1244c|M.bovis_AF2122/97 HSHTWYTALAGHLAAILYDIPHILTAHSLEPLRPWKKEQLGGGYQVSTWV
Rv1212c|M.tuberculosis_H37Rv HSHTWYTALAGHLAAILYDIPHVLTAHSLEPLRPWKKEQLGGGYQVSTWV
Mflv_0483|M.gilvum_PYR-GCK HNHSLNPV--PVLVARRLPVPVLTTLHTP-------------PFPALEAA
Mvan_2096|M.vanbaalenii_PYR-1 HAHDWLVATPAVALAQFFDVPLVSTIHATEAG--RHSGWVSGQVSRQVHA
MAB_1014c|M.abscessus_ATCC_199 DAVLISHHSFATQAAFATEAPVVAYVHSPAR------WAWDRTFRDHEMA
. * : *
MSMEG_5641|M.smegmatis_MC2_155 YYRELGDDIGLIAISDRQR------ELAPDLNWVGRVHNALRIDDWPFN-
TH_0092|M.thermoresistible__bu YYRELGHDVGLIAISDRQR------ELAPDLNWIGRVHNALRIHDWPFK-
MAV_1024|M.avium_104 YYRELSGDVGLVAISDRQR------QLAPELNWVGRVHNALRIDEWPFE-
MMAR_2092|M.marinum_M MHEKIVGRIAVSDLARRWQ------MEALGSDAV-EIPNGVDVGSFASS-
MUL_3252|M.ulcerans_Agy99 MHEKIVGRIAVSDLARRWQ------MEALGSDAV-EIPNGVDVGSFASS-
MLBr_00452|M.leprae_Br4923 WHEKIIGRIAVSDLARRWQ------MEALGSDAV-EIPNGVNVDSLSSA-
Mb1244c|M.bovis_AF2122/97 EQTAVLAANAVIAVSSAMRNDMLRVYPSLDPNLVHVIRNGIDTETWYPAG
Rv1212c|M.tuberculosis_H37Rv EQTAVLAANAVIAVSSAMRNDMLRVYPSLDPNLVHVIRNGIDTETWYPAG
Mflv_0483|M.gilvum_PYR-GCK VGAVARSGQAFAAVSRQAAA----AWEHVGIRRMALVRNGIDTSRWPAG-
Mvan_2096|M.vanbaalenii_PYR-1 LESWLVRDSDSLITCSASMRDEITTLFGPELADITVIPNGIDTDGWPFA-
MAB_1014c|M.abscessus_ATCC_199 SRAGRIALSALGKLARRGE-----LRAAPRLSHVIANSHAVAERIRDWWG
. : :.:
MSMEG_5641|M.smegmatis_MC2_155 -------TVKKDY------ALFLGRY-APYKGAHLALEAG--HAAGMPLV
TH_0092|M.thermoresistible__bu -------REKGDY------ALFLGRF-APYKGAHLAIQAA--DRAGIRLV
MAV_1024|M.avium_104 -------TEKHDY------ALFLGRY-APYKGAHLALRAA--HEAGIPLV
MMAR_2092|M.marinum_M -------SCLDGYPRPGKTVLFLGRYDEPRKGMSVLLEAL--PKLVERFS
MUL_3252|M.ulcerans_Agy99 -------SCLDGYPRPGKTVLFLGRYDEPRKGMSVLLEAL--PKLVERFI
MLBr_00452|M.leprae_Br4923 -------PQLAGYPRLGKTVLFLGRYDEPRKGMSVLLDAL--PGVMECFD
Mb1244c|M.bovis_AF2122/97 PARTGSVLAELGVDPNRPMAVFVGRITRQKGVVHLVTAAHR-FRSDVQLV
Rv1212c|M.tuberculosis_H37Rv PARTGSVLAELGVDPNRPMAVFVGRITRQKGVVHLVTAAHR-FRSDVQLV
Mflv_0483|M.gilvum_PYR-GCK ---------PGGE------DLVWSGRLLEEKGPHLAVDAA--LRAGRRIV
Mvan_2096|M.vanbaalenii_PYR-1 ---------PHRPRPGPAELLYFGRLEYEKGVHDLIAALPR-IRRAHPGT
MAB_1014c|M.abscessus_ATCC_199 -------LPSTVISPPVRIDRFSPDPSIRREDFYLCAGRLVPYKRADLAI
:
MSMEG_5641|M.smegmatis_MC2_155 LAGKCSEPPEIAYFDEQVKPLLTDSDH----VFGMADAQAKRKLLAEARC
TH_0092|M.thermoresistible__bu LAGKCDEPSEKAYFEEQVRPLLNENDE----VFGEADAIAKRELLANARC
MAV_1024|M.avium_104 LAGKCSEPSEKEYFEDCVRPLLTDNDH----VFGEADAVSKRKLLSRARC
MMAR_2092|M.marinum_M DVQLLIVGRGDEDELRDEAGELAEHMR----FLGQVDDAGKASAMRSADV
MUL_3252|M.ulcerans_Agy99 DVQLLIVGRGDEDELRDEAGELAEHMR----FLGQVDDAGKASAMRSADV
MLBr_00452|M.leprae_Br4923 DVQLLIVGRGDEEQLRSQAGGLVEHIR----FLGQVDDAGKAAAMRSADV
Mb1244c|M.bovis_AF2122/97 LCAGAADTPEVADEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATV
Rv1212c|M.tuberculosis_H37Rv LCAGAADTPEVADEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATV
Mflv_0483|M.gilvum_PYR-GCK LAGPIVD---DHFFRRRIAPTLGSRAS----YAGHLGQRELATLVGRAAA
Mvan_2096|M.vanbaalenii_PYR-1 TLTIAGDGTQLDFLVEQARKHKVVKATN---FIGRVGHSELLRLLHRADA
MAB_1014c|M.abscessus_ATCC_199 RAAQRANCRLVVLGEGRFREHLEDIAGPETTFLGAASDDVLLDMYRRCRA
. .
MSMEG_5641|M.smegmatis_MC2_155 LVFPIQWEEPFGMVMIEAMACGTPVVALRGGAVPEVIVDGVTGVICD-VP
TH_0092|M.thermoresistible__bu LLFPIQWEEPFGMVMIEAMACGTPVVALRGGAVPEVIVDGVTGVICE-DP
MAV_1024|M.avium_104 LLFPIQWEEPFGIVMIEAMVCGTPVVALRGGAVSEVVADGVTGVVCD-HP
MMAR_2092|M.marinum_M YCAPNTGGESFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEIGRLVP-VD
MUL_3252|M.ulcerans_Agy99 YCAPNTGGESFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEIGRLVP-VD
MLBr_00452|M.leprae_Br4923 YCAPNIGGESFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEVGHLVP-AG
Mb1244c|M.bovis_AF2122/97 FVCPSVY-EPLGIVNLEAMACATAVVASDVGGIPEVVADGITGSLVH-YD
Rv1212c|M.tuberculosis_H37Rv FVCPSVY-EPLGIVNLEAMACATAVVASDVGGIPEVVADGITGSLVH-YD
Mflv_0483|M.gilvum_PYR-GCK ALVTPLWDEPYGQVVVEAMACGTPVVAFAGGGIPELVDEHSGRLVEPGDV
Mvan_2096|M.vanbaalenii_PYR-1 AVLPSHY-EPFGIVALEAAATGTPLVTSTAGGLGEAVIDGVTGLSYPPGD
MAB_1014c|M.abscessus_ATCC_199 LLMPGVE--DFGIVPVEAMACGTPVLALGEGGALDTVTPGITGEHMR---
. * * :** . .*.::: .. :
MSMEG_5641|M.smegmatis_MC2_155 EELPAAMEKATHLDPAACRRHVAAHFGVGRFGAGYEQIYRNVLR----QR
TH_0092|M.thermoresistible__bu AELPAAIERTADMDPAECRRHVAANFDIERFGSGYEQIFRGVVDGSMAVR
MAV_1024|M.avium_104 DELPGAIARAQTLDPHACRRHVAANFAVAQFGSAYEAIYRNVLQHATAAP
MMAR_2092|M.marinum_M DSDALAAALIEVLDSQELRERYVAAGTEAVRRYDWSVVASQIMRVYETVA
MUL_3252|M.ulcerans_Agy99 DSDALAAALIEVLDSQELRERYVAAGTEAVRRYDWSVVASQIMRVYETVA
MLBr_00452|M.leprae_Br4923 DSAALADALVALLRNDVLRERYVAAGAEAVRRYDWSVVASQIMRVYETVA
Mb1244c|M.bovis_AF2122/97 AD--DATGYQARLAEAVNALVADPATAERYGHAGRQRCIQEFSWAYIAEQ
Rv1212c|M.tuberculosis_H37Rv AD--DATGYQARLAEAVNALVADPATAERYGHAGRQRCIQEFSWAYIAEQ
Mflv_0483|M.gilvum_PYR-GCK AALAAAVREAVALPRAGVRRVAVQRHGLARMVTGYVALYRALIAEATPPP
Mvan_2096|M.vanbaalenii_PYR-1 VAALARAVRAVLDSPAAAQRRARAARERLTSDFSWHTVAAETAQVYLAAK
MAB_1014c|M.abscessus_ATCC_199 ---AGPDDAVVEQLAALMRDFDPADYDAGTIRARACEFSPEAFRARIAET
MSMEG_5641|M.smegmatis_MC2_155 TRMTLREVLT--EPPGVA----ERASA---------
TH_0092|M.thermoresistible__bu SNVALRQILP--ETGERD----EQIA----------
MAV_1024|M.avium_104 RRMRSTGLVESIETGRRACDFRQKAPA---------
MMAR_2092|M.marinum_M GAGVKVQVAS--------------------------
MUL_3252|M.ulcerans_Agy99 GAGVKVQVAS--------------------------
MLBr_00452|M.leprae_Br4923 TSGSKVQVAS--------------------------
Mb1244c|M.bovis_AF2122/97 TLDIYRKVCA--------------------------
Rv1212c|M.tuberculosis_H37Rv TLDIYRKVCA--------------------------
Mflv_0483|M.gilvum_PYR-GCK RPPKLHSSSESANQSQAVSATARACLTNVSGVSAET
Mvan_2096|M.vanbaalenii_PYR-1 RAVRRPQPRRPIEERPLPDR----------------
MAB_1014c|M.abscessus_ATCC_199 VQGAVRA-----------------------------