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RLRLGRPDITRYADRFDVPAAGPGGLSVTWLGVASLLIDDGSSALLTDGYFSRPGLARVVAGKVSPSPPR VDGCLARAKVSRLEAVIPVHTHFDHALDSALVADRTGALLVGGESAANVGRGYGLPEDRIVVAADGEPIR LGAFDVTLVKSHHCPPDRFPGVIAEPLIPPARASAYRCGESWSTLVRHRPTGRRLLICGSAGFVPGALAG QRAGAAYLSVGQLGLRPRSYLDEYWDQTVRTVGARRVILIHWDDFFRPLSKPLRALPYAGDDLDSSIRVL DELAERDGVALHLPSVWRREDPWA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0579 | - | - | 100% (305) | hypothetical protein MAV_0579 |
| M. avium 104 | MAV_1029 | - | 7e-06 | 23.73% (295) | metallo-beta-lactamase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3608 | - | 1e-136 | 83.45% (278) | hypothetical protein Mb3608 |
| M. gilvum PYR-GCK | Mflv_1449 | - | 1e-114 | 64.05% (306) | hypothetical protein Mflv_1449 |
| M. tuberculosis H37Rv | Rv3577 | - | 1e-136 | 83.45% (278) | hypothetical protein Rv3577 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0960 | - | 1e-05 | 26.32% (133) | hypothetical protein MAB_0960 |
| M. marinum M | MMAR_5077 | - | 1e-133 | 71.80% (305) | hypothetical protein MMAR_5077 |
| M. smegmatis MC2 155 | MSMEG_6071 | - | 1e-123 | 67.54% (305) | metallo-beta-lactamase superfamily protein |
| M. thermoresistible (build 8) | TH_1750 | - | 1e-122 | 68.20% (305) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4153 | - | 1e-132 | 71.48% (305) | hypothetical protein MUL_4153 |
| M. vanbaalenii PYR-1 | Mvan_5335 | - | 1e-112 | 62.75% (306) | hypothetical protein Mvan_5335 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3608|M.bovis_AF2122/97 -------------------------------------MPTARSDAP----
Rv3577|M.tuberculosis_H37Rv -------------------------------------MPTARSDAP----
MAV_0579|M.avium_104 -----------------------------------MRLRLGRPDITRYAD
MMAR_5077|M.marinum_M -----------------------------------MRLRFGRPDLKRYSH
MUL_4153|M.ulcerans_Agy99 -----------------------------------MRLRFGRPDLKRYSH
Mflv_1449|M.gilvum_PYR-GCK -----------------------------------MRCKPGRPDLDAYAT
Mvan_5335|M.vanbaalenii_PYR-1 -----------------------------------MRLKLGRPDLQAYSA
MSMEG_6071|M.smegmatis_MC2_155 -----------------------------------MRLKPGRPDLADHAR
TH_1750|M.thermoresistible__bu -----------------------------------MRIRPGRPSLTPYAH
MAB_0960|M.abscessus_ATCC_1997 MRALWVGAGAAIASTWIGRALRDVPQTLGASKGRIAEVAKGSPQYRGGTF
. ..
Mb3608|M.bovis_AF2122/97 ---------------LSVTWMGVATLLVDD-------------GSSALMT
Rv3577|M.tuberculosis_H37Rv ---------------LSVTWMGVATLLVDD-------------GSSALMT
MAV_0579|M.avium_104 RFDVPA---AGPGG-LSVTWLGVASLLIDD-------------GSSALLT
MMAR_5077|M.marinum_M RFGVPA---AKPDAPLSAMWIGVSTVLLDD-------------GSSALMT
MUL_4153|M.ulcerans_Agy99 RFGVPA---AKPDAPLSAMWIGVSTVLLDD-------------GSSALMT
Mflv_1449|M.gilvum_PYR-GCK YFDLPA---ATPASPVTVSWAGVTTLLIND-------------GTSALMT
Mvan_5335|M.vanbaalenii_PYR-1 YFDLPP---APPGAPVTVTWAGVTTLLVDD-------------GESAVMT
MSMEG_6071|M.smegmatis_MC2_155 FFDAPT---ATPDSPVTVTWAGVTTLLVDD-------------GTSALLT
TH_1750|M.thermoresistible__bu RFDVPA---AAATSRLTVTWAGVTTLLIDD-------------GKSALLT
MAB_0960|M.abscessus_ATCC_1997 HNAEPARQFSPDAETTTVVWDVLTRRGVGTPKGQVPLAVPELSGPPADLA
:. * :: :. * .* ::
Mb3608|M.bovis_AF2122/97 DGYFSRPGLARVAAG-KVSPSAERVDGCLAR---------------ANVS
Rv3577|M.tuberculosis_H37Rv DGYFSRPGLARVAAG-KVSPSAERVDGCLAR---------------ANVS
MAV_0579|M.avium_104 DGYFSRPGLARVVAG-KVSPSPPRVDGCLAR---------------AKVS
MMAR_5077|M.marinum_M DGYFSRPSLAQVAAG-KLAPSAARVDGCLAQ---------------AKAS
MUL_4153|M.ulcerans_Agy99 DGYFSRPSLAQVAAG-KLAPSAARVDGCLAQ---------------AKAS
Mflv_1449|M.gilvum_PYR-GCK DGFFSRPGLLRVATRRPLASSDSRIDAALQR---------------LGVT
Mvan_5335|M.vanbaalenii_PYR-1 DGFFSRPSHLSVAAR-PLRSSRSRIDDALSR---------------LGVR
MSMEG_6071|M.smegmatis_MC2_155 DGFFSRPGLLTVGLR-PLAPNVPRIDGCLAR---------------LGVD
TH_1750|M.thermoresistible__bu DGFFSRPALATVALR-RLEPDTARIEGSLAR---------------LRLH
MAB_0960|M.abscessus_ATCC_1997 ATWFGHSSVLVEIDGYRVLTDPVWSDRCSPSRVVGPHRQHPVPVELSALP
:*.:.. : .. : .
Mb3608|M.bovis_AF2122/97 RLTAVIPVHTHIDHA-MDSALVADRTG-AQLVGGESAANVGRGYGLPEES
Rv3577|M.tuberculosis_H37Rv RLTAVIPVHTHIDHA-MDSALVADRTG-AQLVGGESAANVGRGYGLPEES
MAV_0579|M.avium_104 RLEAVIPVHTHFDHA-LDSALVADRTG-ALLVGGESAANVGRGYGLPEDR
MMAR_5077|M.marinum_M ELAAVIPVHTHIDHA-MDSALVADRTG-ALLVGGESAANIGRGYGLAEDR
MUL_4153|M.ulcerans_Agy99 ELAAVIPVHTHIDHA-MDSALVADRTG-ALLVGGESAANIGRGYGLADDR
Mflv_1449|M.gilvum_PYR-GCK RLDGVTPVHTHFDHA-MDSAAVAGRTG-ARLIGGSSAAHIGRGHGL--DR
Mvan_5335|M.vanbaalenii_PYR-1 RLDAVTPVHTHYDHA-MDSAVVADLTG-ARLIGGRSAAAIGRGHGL--DR
MSMEG_6071|M.smegmatis_MC2_155 RLAAVLPVHTHFDHA-MDSAVVAERTG-AALVGGSSAAQIGIGGGLPDDR
TH_1750|M.thermoresistible__bu RLAAVIPVHTHYDHV-LDSPAVADRTG-AVLIGGASAAQVGRGAGLPDDR
MAB_0960|M.abscessus_ATCC_1997 ALDAVVISHDHYDHLDMDSIIALTRSQNAVFVVPLGVGAHLRGWGVSPAR
* .* * * ** :** . : * :: ... * *:
Mb3608|M.bovis_AF2122/97 LVVAVPGEPIQLGAFDVTLVESHHCPPDRFPGVISAPLTPPVKASAYRCG
Rv3577|M.tuberculosis_H37Rv LVVAVPGEPIQLGAFDVTLVESHHCPPDRFPGVISAPLTPPVKASAYRCG
MAV_0579|M.avium_104 IVVAADGEPIRLGAFDVTLVKSHHCPPDRFPGVIAEPLIPPARASAYRCG
MMAR_5077|M.marinum_M LVVAVPGQSMELGGYDVTLIESHHCPPDRFPGVISEPVVPPVKASAYRCG
MUL_4153|M.ulcerans_Agy99 LVVAVPGQSMELGAYDVTLIESHHCPPDRFPGVISEPVVPPVKASAYRCG
Mflv_1449|M.gilvum_PYR-GCK VEVVTSGDATAVGAFDVTLIESHHCPPDRFPGAITAPVAPRASVSAYRCG
Mvan_5335|M.vanbaalenii_PYR-1 VDVVAPAETVSVGSYDITLVEGSHCPPDRFPGTITAPVISPARVSAYRCG
MSMEG_6071|M.smegmatis_MC2_155 IVTVTPGEPVAMEAYDVTLFVSEHCPPDRFPGVITEPVVPPAKASAYKCG
TH_1750|M.thermoresistible__bu IVVAADGASVSAGSFDITLIDTGHCPPDRFPGTIDAPVAPPARVSAYRCG
MAB_0960|M.abscessus_ATCC_1997 VIELDWDQSHQLGKLTLTCTQARHFSGR------SITRNTTLWASWAFAG
: . :* * . . . .* .*
Mb3608|M.bovis_AF2122/97 EAWSTLVHHRPSGRRLLIQDSAGFVSGALAGYRADAAYLSVGQLGLQPPS
Rv3577|M.tuberculosis_H37Rv EAWSTLVHHRPSGRRLLIQDSAGFVSGALAGYRADAAYLSVGQLGLQPPS
MAV_0579|M.avium_104 ESWSTLVRHRPTGRRLLICGSAGFVPGALAGQRAGAAYLSVGQLGLRPRS
MMAR_5077|M.marinum_M EAWSTHIHHRPSGRRLLIQGSAGFVAGALDGYRAEVVYLGVGQLGLQRRS
MUL_4153|M.ulcerans_Agy99 EAWSTHIHHRPSGRRLLIQGSAGFVAGALDGYRAEVVYLGVGQLGLQRRS
Mflv_1449|M.gilvum_PYR-GCK EAWSTLVRHRGTGRGLLIVGSAGFVPGALAGRHADVVYLGVGQLGLQPHD
Mvan_5335|M.vanbaalenii_PYR-1 EAWSTLVHHRPTGVGLLVVGSAGFVPDALAGRRADVVYLGVGQLGLQPEG
MSMEG_6071|M.smegmatis_MC2_155 EAWSTLVHHRPSDRRVLIVGSAGAVPGALAGQRADVVYLGVGQLGRQPER
TH_1750|M.thermoresistible__bu EAWSLLVGHRPSGRRLLIVGSAGFRRGALAGQHAEVAYLGVGQLGLQPER
MAB_0960|M.abscessus_ATCC_1997 PKHKVFFGGDTGYTKAFKVIGDTYGPFDLTLLPVGAYNTSWADIHMNPEE
. . : . * . . . .:: .
Mb3608|M.bovis_AF2122/97 YLLEYWTETVRTVGVRRVILIHWDDFFRPLSKPLRALPYAADDLDLSIRI
Rv3577|M.tuberculosis_H37Rv YLLEYWTETVRTVGVRRVILIHWDDFFRPLSKPLRALPYAADDLDLSIRI
MAV_0579|M.avium_104 YLDEYWDQTVRTVGARRVILIHWDDFFRPLSKPLRALPYAGDDLDSSIRV
MMAR_5077|M.marinum_M YLIDYWNEVVRAVAARRVVLVHWDDFFRPLSKPMRAFPYAADDLDMSIRI
MUL_4153|M.ulcerans_Agy99 YLIDYWNEVVRAVAARRVVLVHWDDFFRPLSKPMRAFPYAADDLDMSIRI
Mflv_1449|M.gilvum_PYR-GCK YLAAYWTETVRTVGARRVVLIHWDDFFRPLDKPLRALPFVADNLDVSMRI
Mvan_5335|M.vanbaalenii_PYR-1 YLVDYWTQTVRTVGARQVVLIHWDDFFRPLDKPLRSLPFAVDDLDVSMRV
MSMEG_6071|M.smegmatis_MC2_155 YLTDYWTQTVRTVGARRVVLIHWDDFFRPLHRPLRALPYVADDLDATMRV
TH_1750|M.thermoresistible__bu YLVDYWTETVRTVGARRVVLTHWDDFFRPLHRPVRALPYAADDLDFSMRV
MAB_0960|M.abscessus_ATCC_1997 AVQTHLDLATAQAPLLPIHWATFNLALHPWAEPIERVLAAAEEQGVTVVA
: : .. . : :: ::* .*:. . . :: . ::
Mb3608|M.bovis_AF2122/97 LDELAAQDGVALQMPTVWRREDPWM--------
Rv3577|M.tuberculosis_H37Rv LDELAAQDGVALQMPTVWRREDPWM--------
MAV_0579|M.avium_104 LDELAERDGVALHLPSVWRREDPWA--------
MMAR_5077|M.marinum_M LDELAAQDGIPLQMPTVWQREDPWV--------
MUL_4153|M.ulcerans_Agy99 LDELAAQDGIPLQMPTVWQREDHWV--------
Mflv_1449|M.gilvum_PYR-GCK LARLAREDGVDLHLPTLWERADPWR--------
Mvan_5335|M.vanbaalenii_PYR-1 LSRLAAEDGVGLHLPTLWQPAAPWS--------
MSMEG_6071|M.smegmatis_MC2_155 LTTLAAHDGVALHLPTLWQRSDPWIETGSGPWR
TH_1750|M.thermoresistible__bu LGGLAETDGIPLHLPTVWQRTDPWR--------
MAB_0960|M.abscessus_ATCC_1997 PRPGQRADARQPAAPDGWWRLT-----------
*. * *