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NRKNVIRTVTVVAVVVVLGWSFFYFSDDTRGYKPVDTSVAMSQINADNVKSAQIDDREQQLRLVLKKSSS DTDGSDKVITKYPTGYAVDLFNALTAKNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGARM GFGFGKSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIPKGVLLYGPPGTGKTL LARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDE REQTLNQLLVEMDGFGDRAGVILIAATNRPDILDPALLRPGRFDRQIPVTNPDLAGRRAVLRVHSKGKPI ADGADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPALEEAVDRVIGGPRRKGRIISEHEKKI TAYHEGGHTLAAWAMPDIDPVYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVF REPTTGAVSDIEQATKVARAMVTEYGMSARLGAVKYGTEHGDPFLGRSMGTQSDYSHEVAREIDEEVRKL IEAAHTEAWEILTEYRDVLDTLAGQLLEKETLHRPELESIFSDVEKRPRLTMFDDFGGRIPSDKPPIKTP GELAIERGEPWPQPMPEPAFKQAIAQATQAAQAAQAAQSASEGTGRGPNGSRGADANPGSHPDYGAPAGW RAPGWPPPSERPQPSGYSPDQPSDTDESSEQQDRDVSRSNPPAHG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_5113 | ftsH | - | 100% (746) | membrane-bound protease FtsH |
M. marinum M | MMAR_0752 | - | 2e-41 | 37.34% (241) | ATPase |
M. marinum M | MMAR_1535 | - | 4e-40 | 39.65% (227) | ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3640c | ftsH | 0.0 | 88.48% (764) | membrane-bound protease FTSH (cell division protein) |
M. gilvum PYR-GCK | Mflv_1416 | - | 0.0 | 84.31% (714) | ATP-dependent metalloprotease FtsH |
M. tuberculosis H37Rv | Rv3610c | ftsH | 0.0 | 88.48% (764) | membrane-bound protease FTSH (cell division protein) |
M. leprae Br4923 | MLBr_00222 | ftsH | 0.0 | 83.88% (788) | putative integral membrane peptidase |
M. abscessus ATCC 19977 | MAB_0533 | - | 0.0 | 83.06% (726) | cell division protein FtsH-like protein |
M. avium 104 | MAV_0542 | hflB | 0.0 | 82.35% (799) | ATP-dependent metallopeptidase HflB |
M. smegmatis MC2 155 | MSMEG_6105 | - | 0.0 | 85.46% (722) | cell division protein |
M. thermoresistible (build 8) | TH_0991 | ftsH | 0.0 | 78.89% (791) | MEMBRANE-BOUND PROTEASE FTSH (CELL DIVISION PROTEIN) |
M. ulcerans Agy99 | MUL_4192 | ftsH | 0.0 | 98.93% (746) | membrane-bound protease FtsH |
M. vanbaalenii PYR-1 | Mvan_5372 | - | 0.0 | 86.01% (729) | ATP-dependent metalloprotease FtsH |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_5113|M.marinum_M ---MNRKNVIRTVTVVAVVVVLGWSFFYFSDDTRGYKPVDTSVAMSQINA MUL_4192|M.ulcerans_Agy99 ---MNRKNVIRTVTAVAVVVVLGWSFFYFSDDTRGYKPVDTSVAMSQINA Mb3640c|M.bovis_AF2122/97 ---MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQING Rv3610c|M.tuberculosis_H37Rv ---MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQING MLBr_00222|M.leprae_Br4923 MLLMNRKNVIRMVTAIAVVVLLGWSFFYFSDDTRGYKFVDTSVAMSQING MAV_0542|M.avium_104 ---MNRKNVIRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAMAQING Mflv_1416|M.gilvum_PYR-GCK ---MNRKNVIRTLTVIAVVLLLGWSFFYFSDDTRGYKPVDTTIAIAQING Mvan_5372|M.vanbaalenii_PYR-1 ---MNRKNVIRTLTVIAVVLLLGWSFFYFSDDTRGYKPVDTSVAMAQISG MSMEG_6105|M.smegmatis_MC2_155 ---MNRKNVIRTLTVIGVVLLLGWSFFYFSDDTRGYKPVDTTVALAQIRG TH_0991|M.thermoresistible__bu ---MNRKTVIRTLTIVAVVLLLGWSFFYFGDDTREYKPVDTSVALAQIQA MAB_0533|M.abscessus_ATCC_1997 ---MNRTNVFRTLGVIVVVLLLGWSFFYFSDDTRGYKPVDTTVAIKQIDT ***..* * : : **::********.**** ** ***::*: ** MMAR_5113|M.marinum_M DNVKSAQIDDREQQLRLVLKKSSSDTDGSDKVITKYPTGYAVDLFNALTA MUL_4192|M.ulcerans_Agy99 DNAKSAQIDDREQQLRLVLKKSSSDTDGSDKVITKYPTGYAVDLFNALTA Mb3640c|M.bovis_AF2122/97 DNVKSAQIDDREQQLRLILKKGNNETDGSEKVITKYPTGYAVDLFNALSA Rv3610c|M.tuberculosis_H37Rv DNVKSAQIDDREQQLRLILKKGNNETDGSEKVITKYPTGYAVDLFNALSA MLBr_00222|M.leprae_Br4923 HNVKSAQIDDREQQLRLTLKKGNNDTDGSDKVITKYPTGYAVDLFNALSA MAV_0542|M.avium_104 DNVKSAQIDDREQQLRLTLKKGNGDTDNSDKVITKYPSGYAVDLFNALSA Mflv_1416|M.gilvum_PYR-GCK DNVNSAQIDDREQQLRLELKNGNGDTENSTQILTKYPTGYGATLFESLQD Mvan_5372|M.vanbaalenii_PYR-1 DNVKSAQIDDREQQLRLELKNGNGDTENSDKIITKYPTGYGVPLFEALQA MSMEG_6105|M.smegmatis_MC2_155 DNVNSAQIDDREQQVRLDLKSGNGDTENSDKIITKYPTGYGVTLFNALQD TH_0991|M.thermoresistible__bu DNVDSAQIDDREQQVRLDLKNANSDTGDSDKIIAKYPTGYAVPLFDALQD MAB_0533|M.abscessus_ATCC_1997 DNVKSARIDDREQQLRLDLKAANGDTEGKDKVITKYPTGYGVPLLEKLNG .*..**:*******:** ** ...:* .. ::::***:**.. *:: * MMAR_5113|M.marinum_M KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG MUL_4192|M.ulcerans_Agy99 KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG Mb3640c|M.bovis_AF2122/97 KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG Rv3610c|M.tuberculosis_H37Rv KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG MLBr_00222|M.leprae_Br4923 KNTKVTTAVNEGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG MAV_0542|M.avium_104 KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG Mflv_1416|M.gilvum_PYR-GCK KNIKTNTVVNQSSIFGTLLIYMLPLLLLVALFVLFSRMQSGGR-MGFGFG Mvan_5372|M.vanbaalenii_PYR-1 KNTKINTVVNQSSILGTLLIYMLPLLLLVGLFVMFSRMQTGGR-MGFGFG MSMEG_6105|M.smegmatis_MC2_155 KGAKTNTVVNQGSVFGTLLIYMLPLLLLVALFVMFSRMQTGGR-MGFGFG TH_0991|M.thermoresistible__bu KNAKVNTVVNQGSVLGTLLIYMLPLLLLVALFVFFMRMQSGGR-MGFGFG MAB_0533|M.abscessus_ATCC_1997 KGAAVNTTVNQGSILGSLLLYLLPVILLVVLFFAFSRMQSGGRGMGFGFG *. .*.**:.*::* **:*:**::*** **. * *** *.* ****** MMAR_5113|M.marinum_M KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP MUL_4192|M.ulcerans_Agy99 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP Mb3640c|M.bovis_AF2122/97 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP Rv3610c|M.tuberculosis_H37Rv KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP MLBr_00222|M.leprae_Br4923 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPCRYQTLGAKIP MAV_0542|M.avium_104 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPGRYQALGAKIP Mflv_1416|M.gilvum_PYR-GCK KSKAKMLSKDMPRTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP Mvan_5372|M.vanbaalenii_PYR-1 KSKAKMLGKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP MSMEG_6105|M.smegmatis_MC2_155 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP TH_0991|M.thermoresistible__bu KSKAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP MAB_0533|M.abscessus_ATCC_1997 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP **:** *.****:************************** ***:****** MMAR_5113|M.marinum_M KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MUL_4192|M.ulcerans_Agy99 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD Mb3640c|M.bovis_AF2122/97 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD Rv3610c|M.tuberculosis_H37Rv KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MLBr_00222|M.leprae_Br4923 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MAV_0542|M.avium_104 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD Mflv_1416|M.gilvum_PYR-GCK KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD Mvan_5372|M.vanbaalenii_PYR-1 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MSMEG_6105|M.smegmatis_MC2_155 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD TH_0991|M.thermoresistible__bu KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MAB_0533|M.abscessus_ATCC_1997 RGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD :************************************************* MMAR_5113|M.marinum_M LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF MUL_4192|M.ulcerans_Agy99 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF Mb3640c|M.bovis_AF2122/97 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF Rv3610c|M.tuberculosis_H37Rv LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF MLBr_00222|M.leprae_Br4923 LFDQAKQNSPCIIFVDEIDAVGRQRGTGLGGGHDEREQTLNQLLVEMDGF MAV_0542|M.avium_104 LFDQAKQNNPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF Mflv_1416|M.gilvum_PYR-GCK LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF Mvan_5372|M.vanbaalenii_PYR-1 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF MSMEG_6105|M.smegmatis_MC2_155 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF TH_0991|M.thermoresistible__bu LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF MAB_0533|M.abscessus_ATCC_1997 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF **:*****.*****************:*********************** MMAR_5113|M.marinum_M GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVTNPDLAGRRAVLRVHS MUL_4192|M.ulcerans_Agy99 GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVTNPDLAGRRAVLRVHS Mb3640c|M.bovis_AF2122/97 GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHS Rv3610c|M.tuberculosis_H37Rv GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHS MLBr_00222|M.leprae_Br4923 GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHS MAV_0542|M.avium_104 DPRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLAVHS Mflv_1416|M.gilvum_PYR-GCK GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVSSPDLAGRRAVLKVHS Mvan_5372|M.vanbaalenii_PYR-1 GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHS MSMEG_6105|M.smegmatis_MC2_155 GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLKVHS TH_0991|M.thermoresistible__bu GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVTNPDLAGRKAVLRVHA MAB_0533|M.abscessus_ATCC_1997 GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVSSPDLAGRKAVLKVHS . * ******************************:.******:*** **: MMAR_5113|M.marinum_M KGKPIADGADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPAL MUL_4192|M.ulcerans_Agy99 KGKPIADGADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPAL Mb3640c|M.bovis_AF2122/97 KGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPAL Rv3610c|M.tuberculosis_H37Rv KGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPAL MLBr_00222|M.leprae_Br4923 KGKPIADDADLDGLAKRTVGMTGADLANVVNEAALLTARENGLVITGPAL MAV_0542|M.avium_104 KGKPIAPDADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITSAAL Mflv_1416|M.gilvum_PYR-GCK QGKPIAEDADLEGLAKRTVGMSGADLANVINEAALLTARENGTIITGPAL Mvan_5372|M.vanbaalenii_PYR-1 QGKPIADDADLDGLAKRTVGMSGADLANVINEAALLTARENGTIITGPAL MSMEG_6105|M.smegmatis_MC2_155 QGKPIAPDADLDGLAKRTVGMSGADLANVINEAALLTARENGTVITGPAL TH_0991|M.thermoresistible__bu QGKPLAPDVDLDGLAKRTVGMSGADLANVINEAALLTARENGTMITGPAL MAB_0533|M.abscessus_ATCC_1997 AGKPFGPDVDFDGLAKRTVGMSGADLANVINEAALLTARENGTVITAAAL ***:. ..*::*********:*******:************ :**..** MMAR_5113|M.marinum_M EEAVDRVIGGPRRKGRIISEHEKKITAYHEGGHTLAAWAMPDIDPVYKVT MUL_4192|M.ulcerans_Agy99 EEAVDRVIGGPRRKGRIISEHEKKITAYHEGGHTLAAWAMPDIDPVYKVT Mb3640c|M.bovis_AF2122/97 EEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVT Rv3610c|M.tuberculosis_H37Rv EEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVT MLBr_00222|M.leprae_Br4923 EEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVT MAV_0542|M.avium_104 EEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVT Mflv_1416|M.gilvum_PYR-GCK EEAVDRVVGGPRRKSRIISEHEKKITAYHEGGHTLAAWAMPDIEPIYKVT Mvan_5372|M.vanbaalenii_PYR-1 EEAVDRVVGGPRRKSRIISEHEKKITAYHEGGHTLAAWAMPDIDPIYKVT MSMEG_6105|M.smegmatis_MC2_155 EEAVDRVVGGPRRKSRIISEHEKKITAYHEGGHTLAAWAMPDIEPIYKVT TH_0991|M.thermoresistible__bu EEAVDRVVGGPRRKSRLISELEKKITAYHEGGHTLAAWAMPDIEPIYKVT MAB_0533|M.abscessus_ATCC_1997 EESVDRVVGGPRRKGRIISEHEKKITAYHEAGHTLAAWAMPDIERVYKVT **:****:******.*:*** *********.************: :**** MMAR_5113|M.marinum_M ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT MUL_4192|M.ulcerans_Agy99 ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT Mb3640c|M.bovis_AF2122/97 ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT Rv3610c|M.tuberculosis_H37Rv ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT MLBr_00222|M.leprae_Br4923 ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT MAV_0542|M.avium_104 ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT Mflv_1416|M.gilvum_PYR-GCK ILARGRTGGHAMAVPEDDKGLMTRSEMIARLVFAMGGRAAEELVFREPTT Mvan_5372|M.vanbaalenii_PYR-1 ILARGRTGGHAMSVPEDDKGLMTRSEMIARLVFAMGGRAAEELVFREPTT MSMEG_6105|M.smegmatis_MC2_155 ILARGRTGGHAVAVPEDDKGLMTRSEMIARLVFAMGGRAAEELVFREPTT TH_0991|M.thermoresistible__bu ILARGRTGGHAVAVPEDDKGLMTRSEMIARLVFAMGGRAAEELVFREPTT MAB_0533|M.abscessus_ATCC_1997 ILARGRTGGHAIAVPEDDKGLATRSEMIAQLVFAMGGRAAEELVFREPTT ***********::***:**** *******:******************** MMAR_5113|M.marinum_M GAVSDIEQATKVARAMVTEYGMSARLGAVKYGTEHGDPFLGRSMGTQSDY MUL_4192|M.ulcerans_Agy99 GAVSDIEQATKVARAMVTEYGMSARLGAVKYGTEHGDPFLGRSMGTQSDY Mb3640c|M.bovis_AF2122/97 GAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQPDY Rv3610c|M.tuberculosis_H37Rv GAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQPDY MLBr_00222|M.leprae_Br4923 GAVSDIEKATKIARSMVTEFGMSSKLGAVRYGSEHGDPFLGRTMGTQADY MAV_0542|M.avium_104 GAVSDIEQATKIARAMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQADY Mflv_1416|M.gilvum_PYR-GCK GASSDIDQATKIARAMVTEYGMSSKLGAVRYGSEHGDPFLGRTMGNQADY Mvan_5372|M.vanbaalenii_PYR-1 GAVSDIEQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTQADY MSMEG_6105|M.smegmatis_MC2_155 GAVSDIEQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTQADY TH_0991|M.thermoresistible__bu GAVSDIEQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTHADY MAB_0533|M.abscessus_ATCC_1997 GAVSDIEQATKKARAMVTEFGMSAKLGAVRYGTEHGDPFLGRTMGTQADY ** ***::*** **:****:***::****:**:*********:**.:.** MMAR_5113|M.marinum_M SHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGQLLEKETLHRP MUL_4192|M.ulcerans_Agy99 SHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGQLLEKETLHRP Mb3640c|M.bovis_AF2122/97 SHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRP Rv3610c|M.tuberculosis_H37Rv SHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRP MLBr_00222|M.leprae_Br4923 SHEVARDIDDEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRP MAV_0542|M.avium_104 SHEVARDIDDEIRKLIEAAHTEAWEILTEYRDILDTLAGQLLEKETLHRA Mflv_1416|M.gilvum_PYR-GCK SHEVAQIIDDEIRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRV Mvan_5372|M.vanbaalenii_PYR-1 SHEVAQIIDDEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRV MSMEG_6105|M.smegmatis_MC2_155 SHEVAQIIDDEVRKLIEAAHTEAWEILTEYRDVLDILAGELLEKETLHRA TH_0991|M.thermoresistible__bu SHEVARDIDDEIRKLIEAAHTEAWEILTEYRDVLDVLAGELLEKETLHRR MAB_0533|M.abscessus_ATCC_1997 SHEVAREIDEEVRNLIEAAHTEAWAILTEYRDVLDTLAGALLEKETVVRK *****: **:*:*:********** *******:** *** ******: * MMAR_5113|M.marinum_M ELESIFSDVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPM MUL_4192|M.ulcerans_Agy99 ELESIFSDVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPM Mb3640c|M.bovis_AF2122/97 ELESIFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPV Rv3610c|M.tuberculosis_H37Rv ELESIFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPV MLBr_00222|M.leprae_Br4923 ELEGIFASVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPV MAV_0542|M.avium_104 ELESIFAGVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPPPA Mflv_1416|M.gilvum_PYR-GCK ELEAIFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAIERGEPWPKPV Mvan_5372|M.vanbaalenii_PYR-1 ELEAIFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAIERGEPWPKPL MSMEG_6105|M.smegmatis_MC2_155 ELEAIFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAMERGEPWPPPV TH_0991|M.thermoresistible__bu ELEVILADVKKRPRLTMFDDFGGRTPSDKPPIKTPGELAMERGEPWPKPE MAB_0533|M.abscessus_ATCC_1997 ELEEIFSGVQRRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPPPV *** *:..*::************* **************:******* * MMAR_5113|M.marinum_M PEPAFKQAIAQATQAAQAA--QAAQSASEGTGRGPNGSRGADAN----PG MUL_4192|M.ulcerans_Agy99 PEPAFKQAIAQAT--------QAAQSASEGTGRGPNGSRGADAN----PG Mb3640c|M.bovis_AF2122/97 PEPAFKAAIAQATQAAEAARSDAGQTGHGANGSPAGTHRSGDRQ---YGS Rv3610c|M.tuberculosis_H37Rv PEPAFKAAIAQATQAAEAARSDAGQTGHGANGSPAGTHRSGDRQ---YGS MLBr_00222|M.leprae_Br4923 PEPAFKAAIARASQAAEASHQAAQSDTDGPPGQGANGSHAGDRQR-QHGP MAV_0542|M.avium_104 PEPAFKAAIAKASEAAAAARLEADRNANGGNGSHAN--QGGNRQ----GP Mflv_1416|M.gilvum_PYR-GCK PEPAFKTAIAQASRAAAEAAPKNGGNGANGAH-APG-------------- Mvan_5372|M.vanbaalenii_PYR-1 PEPAFKTAIAQASRAAAEQAQKNGGNGSQASNGVPGG------------P MSMEG_6105|M.smegmatis_MC2_155 PEPAFKAAIAAANREAEKRNGTNGAP-SNGAP-APAG------------P TH_0991|M.thermoresistible__bu PEPAFKVAIAEATRAAEAASGQNGQNGHNGTPGPTGPNGTPSAPAQQPAP MAB_0533|M.abscessus_ATCC_1997 PEPAFKKAIAEQAAAAAPANGVPPAPAGPHGHLPNGQGG-------QPVP ****** *** MMAR_5113|M.marinum_M SHPDYGAPAGWRAPGWPPPSE----------------RPQPSGYSPDQ-- MUL_4192|M.ulcerans_Agy99 SHPDYGAPAGWRAPGWPPPSE----------------RPQPSGYSPDQ-- Mb3640c|M.bovis_AF2122/97 TQPDYGAPAGWHAPGWPPRSS--------HRPS---YSGEPAPTYPGQ-- Rv3610c|M.tuberculosis_H37Rv TQPDYGAPAGWHAPGWPPRSS--------HRPS---YSGEPAPTYPGQ-- MLBr_00222|M.leprae_Br4923 TQPDYGAPPGWHAPGWPPQQPPDYWYPPEQQPSQSPYWPQPAPSYPGQAP MAV_0542|M.avium_104 TQPDYGAPAGWRAPGWPPQQSQQP--NYWHPPAQPPYWQQPAHGYPGQQP Mflv_1416|M.gilvum_PYR-GCK --PDYGAPAGWHAPGWPPPPGGPQQQQPPQQ---QGYWYPGPPQQQGWQG Mvan_5372|M.vanbaalenii_PYR-1 TQPDYGAPAGWHAPGWPPQAGGP---HPPQP---QGYWYP-PPPPSGWQG MSMEG_6105|M.smegmatis_MC2_155 TQPDYGAPAGWHAPGWPPPQQSQQPGYQPQ----QGYWYP-PPHPSGWQ- TH_0991|M.thermoresistible__bu VVPDYGAPAGWHAPGWPPQPTPQQQPPPYQQP--HGQWYP-PQQQPGWQ- MAB_0533|M.abscessus_ATCC_1997 PGVNYGAPAGWHAPGWPPPGQAPHP-------------------QPGYQ- :****.**:****** . MMAR_5113|M.marinum_M --------------------------------------PSDTDESSEQQD MUL_4192|M.ulcerans_Agy99 --------------------------------------PSDTDESSEQQD Mb3640c|M.bovis_AF2122/97 -----PYP--------------------------TGQADPGSDESSAEQD Rv3610c|M.tuberculosis_H37Rv -----PYP--------------------------TGQADPGSDESSAEQD MLBr_00222|M.leprae_Br4923 P----PYPS----------------YPPCPSYPPPGQSAPDAGKPPAQLD MAV_0542|M.avium_104 YPGQQPYPGQPGGPAQSGPPQARPPYPPYPPYPPPGQPAPEGG-SPDRQD Mflv_1416|M.gilvum_PYR-GCK NAPTPAYPG----------------YPPYQPYPQPGQHAPHGGAPAPNPT Mvan_5372|M.vanbaalenii_PYR-1 APQAPAYPG----------------YPPYQPHSQPGQPAPHGGAAAASPK MSMEG_6105|M.smegmatis_MC2_155 --QPQPYP--------------------YQPYPHPGQQGTS--PEHGRPS TH_0991|M.thermoresistible__bu -QQQQPYPSQ---------------YSPYQPYPQPSPPAPPGGAAPND-- MAB_0533|M.abscessus_ATCC_1997 -----PYPP--------------------QPYPYP----------VPTPH MMAR_5113|M.marinum_M RDVSRSNPPAHG---------------------- MUL_4192|M.ulcerans_Agy99 RDVSRSNPPAHG---------------------- Mb3640c|M.bovis_AF2122/97 DEVSRTKP-AHG---------------------- Rv3610c|M.tuberculosis_H37Rv DEVSRTKP-AHG---------------------- MLBr_00222|M.leprae_Br4923 EGVSPSNPPAHG---------------------- MAV_0542|M.avium_104 DDVSRSNPPAHG---------------------- Mflv_1416|M.gilvum_PYR-GCK DDPGQDRGRENGHRDTERRDTDRGDTNRNGPANG Mvan_5372|M.vanbaalenii_PYR-1 EDPGHEGGGENGRSAP--------------PSNG MSMEG_6105|M.smegmatis_MC2_155 EQSGQDDGHTGDRSNP----------------HG TH_0991|M.thermoresistible__bu QESGQDPNRTNPPGQG------------------ MAB_0533|M.abscessus_ATCC_1997 QQPGPAPDEGSESKG------------------- .