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VSVRDSVLALLTQWDPPDAAQDSLRHAVLAFVHARPDACRRECEPGHVTASTLVLDHTGDRVLLTLHRRL GRWVQLGGHCDDDDAGIVAAALREATEESGIDGLRMAPGLAAVHVHPVTCSLGLPTRHLDLQFVAHAPAG ARIAISDESEDLRWWPVDALPAGTDHALAYLVAQATRASR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4227 | - | - | 100% (180) | hydrolase, nudix family protein, putative |
| M. avium 104 | MAV_0457 | - | 1e-05 | 30.72% (153) | hydrolase, nudix family protein |
| M. avium 104 | MAV_3798 | - | 6e-05 | 32.74% (113) | nudix hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3696c | - | 2e-05 | 36.05% (86) | hypothetical protein Mb3696c |
| M. gilvum PYR-GCK | Mflv_4732 | - | 1e-66 | 66.86% (175) | NUDIX hydrolase |
| M. tuberculosis H37Rv | Rv3672c | - | 2e-05 | 36.05% (86) | hypothetical protein Rv3672c |
| M. leprae Br4923 | MLBr_00755 | - | 6e-25 | 70.00% (70) | hypothetical protein MLBr_00755 |
| M. abscessus ATCC 19977 | MAB_3609 | - | 2e-64 | 62.36% (178) | hypothetical protein MAB_3609 |
| M. marinum M | MMAR_1278 | - | 2e-73 | 75.14% (177) | hypothetical protein MMAR_1278 |
| M. smegmatis MC2 155 | MSMEG_1827 | - | 2e-70 | 70.06% (177) | hydrolase, nudix family protein, putative |
| M. thermoresistible (build 8) | TH_0778 | - | 1e-69 | 71.51% (172) | hydrolase, nudix family protein, putative |
| M. ulcerans Agy99 | MUL_2609 | - | 2e-69 | 75.00% (168) | hypothetical protein MUL_2609 |
| M. vanbaalenii PYR-1 | Mvan_1731 | - | 3e-64 | 65.71% (175) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1278|M.marinum_M ------MKVAPVG--VRESAIAMLSQWRA-------------PDPAQDSL
MUL_2609|M.ulcerans_Agy99 ----------------------MLSQWRA-------------PDPAQDSL
MAV_4227|M.avium_104 -----------MS--VRDSVLALLTQWDP-------------PDAAQDSL
Mflv_4732|M.gilvum_PYR-GCK -----------MS--LHQSTVDVLTAWNP-------------PDPAQDSL
Mvan_1731|M.vanbaalenii_PYR-1 -----------MS--LHQSTVDTLTAWRP-------------ADPAQDSL
MSMEG_1827|M.smegmatis_MC2_155 -----------MS--LHDSATRLLTHWDA-------------PDPAQDSL
TH_0778|M.thermoresistible__bu -----------MSDPLHASAVRLLTEWRA-------------PDPAQDSL
MAB_3609|M.abscessus_ATCC_1997 MTARHPGEGHQMPSDLRESAIELLSSWQA-------------PDAEQDSL
MLBr_00755|M.leprae_Br4923 --------------------------------------------------
Mb3696c|M.bovis_AF2122/97 MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDAYRRRL
Rv3672c|M.tuberculosis_H37Rv MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDAYRRRL
MMAR_1278|M.marinum_M RHAVLAFLHAR-ADACLRECEAGHITASTLVLD------------ERG-H
MUL_2609|M.ulcerans_Agy99 RHAVLALLHAR-ADACLRECEAGHITASTLVLD------------DRG-H
MAV_4227|M.avium_104 RHAVLAFVHAR-PDACRRECEPGHVTASTLVLD------------HTGDR
Mflv_4732|M.gilvum_PYR-GCK RHSVLAFLAAR-EDACLRECAPGHITGSALVVD------------HRGER
Mvan_1731|M.vanbaalenii_PYR-1 RHAVLAFLAAR-EDACLRDCVPGHITGSALVLD------------HSGRH
MSMEG_1827|M.smegmatis_MC2_155 RHAVLSFLAAR-PDACLRACVPGHITASALVID------------HTGTH
TH_0778|M.thermoresistible__bu RHAVLSFLAAR-PDGCRRECAPGHITASALVVD------------HTGTQ
MAB_3609|M.abscessus_ATCC_1997 RHSVLAFLDAN-PDACRRRSAAGHVTASALVVN------------HDGSQ
MLBr_00755|M.leprae_Br4923 --------------------------------------------------
Mb3696c|M.bovis_AF2122/97 PADVLAMVTAAGAVSAMTSSRRDHREAAVLVLFSGPEAGPGDGGVPDDAD
Rv3672c|M.tuberculosis_H37Rv PADVLAMVTAAGAVSAMTSSRRDHREAAVLVLFSGPEAGPGDGGVPDDAD
MMAR_1278|M.marinum_M VLLTLHP-----RLGRWVQLGGHCEDDHD-IVAAALREATEESGIDNLLI
MUL_2609|M.ulcerans_Agy99 VLLTLHP-----RLGRWVQLGGHCEDDHD-IVAAALREATEESGINNLLI
MAV_4227|M.avium_104 VLLTLHR-----RLGRWVQLGGHCDDDDAGIVAAALREATEESGIDGLRM
Mflv_4732|M.gilvum_PYR-GCK ALLTLHP-----RVGRWLQLGGHCEPTDETIVAAALREATEESGISGLTI
Mvan_1731|M.vanbaalenii_PYR-1 ALLTLHP-----RIGRWLQLGGHCEPEDETIVAAALREATEESGIDGLTI
MSMEG_1827|M.smegmatis_MC2_155 TLLTLHP-----RFGRWLQLGGHCEDTDPDIHAAALREATEESGIEGLTI
TH_0778|M.thermoresistible__bu ALLTLHP-----RIGRWVQLGGHCEPGDADIRAAALREAAEESGITGLRV
MAB_3609|M.abscessus_ATCC_1997 ALLTLHP-----RVGKWLQLGGHCEEEDPTIHAAALREATEESGIDDLLL
MLBr_00755|M.leprae_Br4923 ---------------------------------MALREATKESGVADLRI
Mb3696c|M.bovis_AF2122/97 LLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALREANEETGIDPSRL
Rv3672c|M.tuberculosis_H37Rv LLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALREANEETGIDPSRL
***** :*:*: :
MMAR_1278|M.marinum_M DP---------ELVAVHVHPVTCSLGVP-----TRHLDLQFVARAPAGAQ
MUL_2609|M.ulcerans_Agy99 DP---------ELVAVHVHPVTCSLGVP-----TRHLDLQFVARAPAGAQ
MAV_4227|M.avium_104 AP---------GLAAVHVHPVTCSLGLP-----TRHLDLQFVAHAPAGAR
Mflv_4732|M.gilvum_PYR-GCK EP---------EPAALHVHPVTCSLGVP-----TRHLDVQFVVRAPEGAE
Mvan_1731|M.vanbaalenii_PYR-1 TS---------EPAALHVHPVTCSLGVP-----TRHLDVQFVVRAPEGAE
MSMEG_1827|M.smegmatis_MC2_155 DP---------DLAALHVHPVTCSLGVP-----TRHLDMQFLVRAPEGAE
TH_0778|M.thermoresistible__bu DD---------ELAAVHVHPVTCSLGVP-----TRHLDLQFVVHAPPAAE
MAB_3609|M.abscessus_ATCC_1997 EP---------NLLGIHVHPITCSLGVP-----TRHLDLQFLAHAPEGAQ
MLBr_00755|M.leprae_Br4923 TP---------ELTTIHVHPVTCSLSEP-----TRHLDLQFVAHALDGVH
Mb3696c|M.bovis_AF2122/97 HPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAETAIVARVPVRAF
Rv3672c|M.tuberculosis_H37Rv HPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAETAIVARVPVRAF
.** *: . * ... : ::.:. .
MMAR_1278|M.marinum_M ITVSE-----ESDDLQWWP------------------PDALPPGTDHALR
MUL_2609|M.ulcerans_Agy99 ITVSE-----ESDDLQWWP------------------PDALPPGTDHALR
MAV_4227|M.avium_104 IAISD-----ESEDLRWWP------------------VDALPAGTDHALA
Mflv_4732|M.gilvum_PYR-GCK IVRSD-----ESLDLRWWP------------------LDKLPEGVDFGLT
Mvan_1731|M.vanbaalenii_PYR-1 ITRSD-----ESLDLRWWP------------------IDELPRDCDFGLT
MSMEG_1827|M.smegmatis_MC2_155 IVCSD-----ESLDLRWWP------------------LDALPDGTDFGLD
TH_0778|M.thermoresistible__bu IACSD-----ESLDLRWWP------------------LDGLPAGADFGLT
MAB_3609|M.abscessus_ATCC_1997 IAVSD-----ESLDLRWWP------------------LDQIPE-EDHSVV
MLBr_00755|M.leprae_Br4923 IVVSD-----ESEALRWWP------------------AEALRP----KLT
Mb3696c|M.bovis_AF2122/97 INPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVISAVLDVAGWAQP
Rv3672c|M.tuberculosis_H37Rv INPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVISAVLDVAGWAQP
* :: . : *. . :
MMAR_1278|M.marinum_M YLVDRAAQRA-------------
MUL_2609|M.ulcerans_Agy99 YLVDRAAQRA-------------
MAV_4227|M.avium_104 YLVAQATRASR------------
Mflv_4732|M.gilvum_PYR-GCK QLAAAAASLY-------------
Mvan_1731|M.vanbaalenii_PYR-1 QLAAAAAGSAAGYSPANVHPP--
MSMEG_1827|M.smegmatis_MC2_155 QLAAAARRQTS------VE----
TH_0778|M.thermoresistible__bu QLVGRFRRVHDR-----------
MAB_3609|M.abscessus_ATCC_1997 VLAQRARNRLR------------
MLBr_00755|M.leprae_Br4923 VARKSARRSR-------------
Mb3696c|M.bovis_AF2122/97 WDTGDIRELDAAMVLIDDESDPR
Rv3672c|M.tuberculosis_H37Rv WDTGDIRELDAAMVLIDDESDPR