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SEVVTGDAVVLDVQIAQLPVRALSALIDIAVIVVGYLLGLMLWAATLTQFDTALSNAILLIFTVLVIVGY PLILETATRGRSVGKIALGLRVVSDDGGPERFRQALFRALASLVEIWMLFGSPAVICSILSPKAKRIGDI FAGTVVVNERGPRLGPPPAMPPSLAWWASSLQLSGLSSGQAEVARQFLSRAAQLDPGLRLQMAYRIAGDV VARIAPPPPPGAPPELVLAAVLAERHRRELARLRPPAPWPAPGYPPAWPGSGPAPQWPAPGPANPGPPEG FSAGFTPPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0408 | - | - | 100% (290) | integral membrane protein |
| M. avium 104 | MAV_3436 | - | 3e-06 | 38.46% (78) | hypothetical protein MAV_3436 |
| M. avium 104 | MAV_4004 | - | 4e-05 | 33.77% (77) | hypothetical protein MAV_4004 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3720 | - | 1e-125 | 75.24% (311) | hypothetical protein Mb3720 |
| M. gilvum PYR-GCK | Mflv_1333 | - | 1e-111 | 69.23% (286) | RDD domain-containing protein |
| M. tuberculosis H37Rv | Rv3695 | - | 1e-125 | 75.24% (311) | hypothetical protein Rv3695 |
| M. leprae Br4923 | MLBr_02312 | - | 3e-69 | 74.40% (168) | hypothetical protein MLBr_02312 |
| M. abscessus ATCC 19977 | MAB_0386c | - | 3e-92 | 59.52% (289) | hypothetical protein MAB_0386c |
| M. marinum M | MMAR_5205 | - | 1e-123 | 74.83% (302) | hypothetical protein MMAR_5205 |
| M. smegmatis MC2 155 | MSMEG_6222 | - | 1e-109 | 66.00% (300) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1718 | - | 1e-105 | 65.31% (294) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4278 | - | 1e-124 | 74.92% (303) | hypothetical protein MUL_4278 |
| M. vanbaalenii PYR-1 | Mvan_5459 | - | 1e-113 | 69.76% (291) | RDD domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1333|M.gilvum_PYR-GCK MVGQQQPVVTGDAVVLDIQIAQLPVRALSALIDVSVVALVYIIGVILWAM
Mvan_5459|M.vanbaalenii_PYR-1 MVAQHQPVVTGDAVVLDVQIAQLPVRVLSALIDVTVVFVVYVLGVILWAV
MSMEG_6222|M.smegmatis_MC2_155 MVSQPEPVVTGDAVVLDVSIAQLPVRVLAILIDIFAIFIFYVVGVLLWSI
TH_1718|M.thermoresistible__bu MAMQPETVVTGDAVVLDVQIAQLPVRAVSALIDAAAIFTLYVLGLMLWAV
MMAR_5205|M.marinum_M ----MSEVVTGDAVVLDVQIAQLPVRAVSAIIDMTVMFIGYIMGLTLWAA
MUL_4278|M.ulcerans_Agy99 ----MSEVVTGDAVVLDVQIAQLPVRAVSAIIDMTVMFIGYIMGLTLWAA
Mb3720|M.bovis_AF2122/97 ----MSEVVTGDAVVLDVQIAQLPVRAVSAVIDITIIFIGYILGLMLWAT
Rv3695|M.tuberculosis_H37Rv ----MSEVVTGDAVVLDVQIAQLPVRAVSAVIDITIIFIGYILGLMLWAT
MAV_0408|M.avium_104 ----MSEVVTGDAVVLDVQIAQLPVRALSALIDIAVIVVGYLLGLMLWAA
MLBr_02312|M.leprae_Br4923 --------------------------------------------------
MAB_0386c|M.abscessus_ATCC_199 ----MSELVTGDAVVLDVKVAQLPVRVVSAFIDIFVQMIVLYGGIFVVAF
Mflv_1333|M.gilvum_PYR-GCK TLSQFDPAFSGAVLIIFTVLALVGYPAIFETATRGRTLGKMALGLRVVSD
Mvan_5459|M.vanbaalenii_PYR-1 TLTQFDPAFSGAVLIIFTVLALVGYPTIFETATRGKTLGKLALGLRVVSE
MSMEG_6222|M.smegmatis_MC2_155 TLTQLDEALSAAILIIFTVLAIVGYPVIMETATRGRSLGKMALGLRVVSE
TH_1718|M.thermoresistible__bu ALASFDDALSAAVLIVFTVLTLVGYPLVFEMATRGRTPGKMAMGLRVVSD
MMAR_5205|M.marinum_M SLSELDEALTIAFLIIFTVLVLVGYPVIMETATRGRSLGKIAMGLRVVSD
MUL_4278|M.ulcerans_Agy99 SLSELDEALTIAFLIIFTVLVLVGYPVIMETATRGRSLGKIAMGLRVVSD
Mb3720|M.bovis_AF2122/97 ALTQFDEALTTAFLIIFTVLALVGYPLVWETATRGRSVGKIVMGLRVVSD
Rv3695|M.tuberculosis_H37Rv ALTQFDEALTTAFLIIFTVLALVGYPLVWETATRGRSVGKIVMGLRVVSD
MAV_0408|M.avium_104 TLTQFDTALSNAILLIFTVLVIVGYPLILETATRGRSVGKIALGLRVVSD
MLBr_02312|M.leprae_Br4923 ------------------------------------------MGLRVVSD
MAB_0386c|M.abscessus_ATCC_199 SLSQFDAALTGALSIVYSVLALVGYPVIWEMATRGRSLGKMAMGLRVVSD
:******:
Mflv_1333|M.gilvum_PYR-GCK DGSPERFRQALFRALAGVIEIWMLTGGPAVLCSLVSSKGKRIGDIFAGTV
Mvan_5459|M.vanbaalenii_PYR-1 DGSPERFRQALFRALAGVIELWMLTGGPAVLCSLLSPKGKRIGDIFAGTV
MSMEG_6222|M.smegmatis_MC2_155 DGSPERFRQALFRGISGFIEIWMLTGGPAVICSLLSSKGKRIGDIFAGTV
TH_1718|M.thermoresistible__bu DGGPERFRQALFRALSSVIEIWMFMGGPAVLCSLISPRGKRIGDYFAGTV
MMAR_5205|M.marinum_M DGGPERFRQALFRALAAVVEIWMLLGSPAVICSMLSPKAKRVGDIFAGTI
MUL_4278|M.ulcerans_Agy99 DGGPERFRQALFRALAAVVEIWMLLGSPAVICSMLSPKAKRVGDIFAGTI
Mb3720|M.bovis_AF2122/97 DGGPERFRQALFRALASVVEIWMLLGSPAVICSMLSPKAKRVGDVFAGTV
Rv3695|M.tuberculosis_H37Rv DGGPERFRQALFRALASVVEIWMLLGSPAVICSMLSPKAKRVGDVFAGTV
MAV_0408|M.avium_104 DGGPERFRQALFRALASLVEIWMLFGSPAVICSILSPKAKRIGDIFAGTV
MLBr_02312|M.leprae_Br4923 DGSPEHFRQALFRVLASVVEIWMLLGSPAVICSMLSPKAKHIGDIFPGTV
MAB_0386c|M.abscessus_ATCC_199 DGGPERLRQAVIRALSAVVEIFMFMGAPAVIASLASTKGKRLGDIFAGTM
**.**::***::* ::..:*::*: *.***:.*: *.:.*::** *.**:
Mflv_1333|M.gilvum_PYR-GCK VISERAPRQAPPPAMPPQLAWWASSLQLSGLAPSQAEMARQFLARAGQLD
Mvan_5459|M.vanbaalenii_PYR-1 VISERAPRQSPPPVMPPQLAWWATTLALSGLSPSQAEIARQFLSRARQLD
MSMEG_6222|M.smegmatis_MC2_155 VISERGPRMQPPPAMPPALAWWASSLQLSGLGPEQAELARQYLNRAQHLD
TH_1718|M.thermoresistible__bu VISERAPRQTPPPPMPPQLAGWAATLELSGLSADQFNLARQYLSRAPQLE
MMAR_5205|M.marinum_M VVSERGPRLAPPPAMPPTLAWWASSLQLSGLSAGQAEVARQFLSRAPQLD
MUL_4278|M.ulcerans_Agy99 VVSERGPRLAPPPAMPPTLAWWASSLQLSGLSAGQAEVARQFLSRAPQLD
Mb3720|M.bovis_AF2122/97 VVSERGPRLGPPPVMPPSLAWWASSLQLSGLTAGQAEVARQFLVRAPQLD
Rv3695|M.tuberculosis_H37Rv VVSERGPRLGPPPVMPPSLAWWASSLQLSGLTAGQAEVARQFLVRAPQLD
MAV_0408|M.avium_104 VVNERGPRLGPPPAMPPSLAWWASSLQLSGLSSGQAEVARQFLSRAAQLD
MLBr_02312|M.leprae_Br4923 VISERRPQRGPSPAMPPSLAWWASSLQLSGLNTRQAELAHQFLSRAPQLD
MAB_0386c|M.abscessus_ATCC_199 VISERGPKLPPPPMMPPQLAQWAQSLQLSGLTSDQADLARQFLNRAGQLA
*:.** *: *.* *** ** ** :* **** . * ::*:*:* ** :*
Mflv_1333|M.gilvum_PYR-GCK PHIRDQMAYRVTSDVVAQISPPPPPGVPPALVLAAVLAERHRRELARLQH
Mvan_5459|M.vanbaalenii_PYR-1 PQVRDQMAYRIASDVVAQISPPPPPGTPPALVLAAVLAERHRRELGRLQQ
MSMEG_6222|M.smegmatis_MC2_155 PRIRDMMGQRILGEVASRISPPPPPGAPPQCVLAAVLAERHRRELARLMP
TH_1718|M.thermoresistible__bu PAVRDEMAYRIAADLAPRISPPPPPGTPPHHLLAAVVAERHRRELARLRP
MMAR_5205|M.marinum_M LRLRHQMAYRIAGDVLSHIAPPPPPGTPPQLVLAAVLAERHRRELARLR-
MUL_4278|M.ulcerans_Agy99 LRLRHQMAYRIAGDVLSHIAPPPPPGTPPQLVLAAVLAERHRRELARLR-
Mb3720|M.bovis_AF2122/97 PALREQMAYRIAGDVVARIAPPPPPGVPPQLVLAAVLAERHRRELLRLRP
Rv3695|M.tuberculosis_H37Rv PALREQMAYRIAGDVVARIAPPPPPGVPPQLVLAAVLAERHRRELLRLRP
MAV_0408|M.avium_104 PGLRLQMAYRIAGDVVARIAPPPPPGAPPELVLAAVLAERHRRELARLR-
MLBr_02312|M.leprae_Br4923 PQLQEQMAYRITGDVMSRIAPPPPSSTPPQLMLAAVLAERHRHKLVQLR-
MAB_0386c|M.abscessus_ATCC_199 PHTRDQMLYQISTDVLASIAPPPPPGTPPQFMLAAVLAERHRRALAQMR-
: * :: :: . *:****...** :****:*****: * ::
Mflv_1333|M.gilvum_PYR-GCK P--APG-------------PGWSAAP------------------PTSPPP
Mvan_5459|M.vanbaalenii_PYR-1 QPFQPG-------------PVWPAPPQPPAATPP-------SWPPAPPSA
MSMEG_6222|M.smegmatis_MC2_155 TPPPPPSPP--------TTPPWSPPGYPAAGYPPQPPVPAYSPPPAVPAH
TH_1718|M.thermoresistible__bu QAAVPAA------------PVWYPPQQPGHPVYPAPPYQPQYQPPQQPAQ
MMAR_5205|M.marinum_M ---PAGAG-----APP-GWPPQTPPAPVWWPGQPAPQPQIQPQFAPDPAP
MUL_4278|M.ulcerans_Agy99 ---PAGAG-----APP-GWPPQTPPAPVWWPGQPAPQPLIQPPFAPDPAP
Mb3720|M.bovis_AF2122/97 TLPPAGQAPWAQMAPHRGWPPGLSGATPWSPQQPV-IPWPEPDPPPQAAP
Rv3695|M.tuberculosis_H37Rv TLPPAGQAPWAQMAPHRGWPPGLSGATPWSPQQPV-IPWPEPDPPPQAAP
MAV_0408|M.avium_104 -------------------PPAPWPAPGYPPAWPGSGPAPQWPAPGPANP
MLBr_02312|M.leprae_Br4923 -------------------PTPVGPT----PSSPTVSKYPVPPRVAWAGI
MAB_0386c|M.abscessus_ATCC_199 -------------------PDYPATPP------------PAPSAPPPAPE
* .
Mflv_1333|M.gilvum_PYR-GCK PPPAAG--GGFTPPS
Mvan_5459|M.vanbaalenii_PYR-1 PPPQHP--GGFAPPS
MSMEG_6222|M.smegmatis_MC2_155 SPPQQPSAGGFAPPR
TH_1718|M.thermoresistible__bu QPPDPSP-GGFVPPS
MMAR_5205|M.marinum_M SPPQGPVGGGFSPPS
MUL_4278|M.ulcerans_Agy99 SPPQGPVGGGFSPPS
Mb3720|M.bovis_AF2122/97 WPQQAPDGPGFSPPG
Rv3695|M.tuberculosis_H37Rv WPQQAPDGPGFSPPG
MAV_0408|M.avium_104 GPPEG-FSAGFTPPR
MLBr_02312|M.leprae_Br4923 CSTQFLVASGHR---
MAB_0386c|M.abscessus_ATCC_199 PSESSTGRSGFATPG
. *.