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SSTDPLITPARLTGFGRTAPSVAQVLRTRDPEVIAKAVARVADSGHSKSRGVIARGLGRSYGDNAQNGGG LVIDMTGLNRIHSISADTRLVDVDAGVSLDQLMKAALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSA GSFGNHVRSMELLMADGTVRTITPDGPDASDAELFWATVGGNGLTGIVLRATIAMTPTETAYFIADGMAT KDLDETVAVHLDGSEADYTYSSAWFDLISPPPKLGRAAVSRGSLARLDQLPKKLAKNPLKFDAPQLLTVP DVFPVSAMNKLSFMAIGEVYYRLGGTYTGKIMNLSQFYHMLDLVSGWNNAYGPRGFAQHQFLVPPDAMDE FKAIIRWIQTRGHYSALNVFKLFGPGNRAPLSFPMAGWNVAMDFPNKPGVNEFLNELDRRVLQFGGRVYT AKDSRTNAETFHAMYPRIDEWIAVRRKVDPTGVFASDMARRLELL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0232 | - | - | 100% (466) | oxidoreductase, FAD-binding |
| M. avium 104 | MAV_1405 | - | 2e-09 | 27.98% (218) | oxidoreductase, FAD-binding |
| M. avium 104 | MAV_0384 | - | 2e-06 | 30.00% (130) | FAD/FMN-containing dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3819 | - | 0.0 | 74.89% (466) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1178 | - | 0.0 | 75.97% (466) | FAD linked oxidase domain-containing protein |
| M. tuberculosis H37Rv | Rv3790 | - | 0.0 | 74.89% (466) | oxidoreductase |
| M. leprae Br4923 | MLBr_00109 | - | 0.0 | 74.02% (458) | putative FAD-linked oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0192c | - | 0.0 | 78.40% (463) | oxidoreductase |
| M. marinum M | MMAR_5352 | - | 0.0 | 77.51% (458) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_6382 | - | 0.0 | 75.11% (466) | oxidoreductase, FAD-binding |
| M. thermoresistible (build 8) | TH_1603 | - | 0.0 | 76.61% (466) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_4969 | - | 0.0 | 77.29% (458) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5627 | - | 0.0 | 75.11% (466) | FAD linked oxidase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3819|M.bovis_AF2122/97 --------------------------------------MLS--VGATTTA
Rv3790|M.tuberculosis_H37Rv --------------------------------------MLS--VGATTTA
MLBr_00109|M.leprae_Br4923 --------------------------------------MLN--MGVSTTA
MMAR_5352|M.marinum_M --------------------------------------MFS--APVPTTP
MUL_4969|M.ulcerans_Agy99 --------------------------------------MFS--APVPTTP
Mflv_1178|M.gilvum_PYR-GCK --------------------------MSTGPQAVPSVTMLS--TEFPTTA
Mvan_5627|M.vanbaalenii_PYR-1 --------------------------------------MLS--TEFPTTA
MSMEG_6382|M.smegmatis_MC2_155 ------------------------------MGAVPSLTMST--TEFPTTT
TH_1603|M.thermoresistible__bu --------------------------------------MRT--TEVETTP
MAV_0232|M.avium_104 --------------------------------------MSS--TDPLITP
MAB_0192c|M.abscessus_ATCC_199 MARASGLCHRPGDCDSHQFHRPARGDLPNPLSRYAQLPMTTPKSELPLTP
* . *.
Mb3819|M.bovis_AF2122/97 TRLTGWGRTAPSVANVLRTPDAEMIVKAVARVAESGGG------RGAIAR
Rv3790|M.tuberculosis_H37Rv TRLTGWGRTAPSVANVLRTPDAEMIVKAVARVAESGGG------RGAIAR
MLBr_00109|M.leprae_Br4923 TRLTGWGRTAPSVANVLSTPDAELISKVVARVADADG-------RGVIAR
MMAR_5352|M.marinum_M TRLTGWGRTAPSVAEVLRTPDPEVIATAVARVADSGA-------RGVIAR
MUL_4969|M.ulcerans_Agy99 TRLTGWGRTAPSVAEVLRTPDPEVIATAVARVADTGA-------RGVIAR
Mflv_1178|M.gilvum_PYR-GCK QRLTGWGRTAPSVAQVLSTPDPEVIVKAVTRAAENP-------GRGVLAR
Mvan_5627|M.vanbaalenii_PYR-1 RRLTGWGRTAPSVARVLATPDPEVIVKAVARAAESGKG----GGRGVIAR
MSMEG_6382|M.smegmatis_MC2_155 KRLMGWGRTAPTVASVLSTSDPEVIVRAVTRAAEEG-------GRGVIAR
TH_1603|M.thermoresistible__bu RRLTGWGRTAPTVAQVLSTSDAEVIAEAVRRTAEQSKA----GARGVIAR
MAV_0232|M.avium_104 ARLTGFGRTAPSVAQVLRTRDPEVIAKAVARVADSG-HSKS---RGVIAR
MAB_0192c|M.abscessus_ATCC_199 RALTGFGRTAPTVAHVLSTPDVDVIAEAVRQVADASSHSPAHLRRGIVAR
* *:*****:** ** * * ::* .* :.*: ** :**
Mb3819|M.bovis_AF2122/97 GLGRSYGDNAQNGGGLVIDMTPLNTIHSIDADTKLVDIDAGVNLDQLMKA
Rv3790|M.tuberculosis_H37Rv GLGRSYGDNAQNGGGLVIDMTPLNTIHSIDADTKLVDIDAGVNLDQLMKA
MLBr_00109|M.leprae_Br4923 GLGRSYGDNAQNGGGLVIDMTPLNTIHCINTDTKLADVDAGVNLNKLMKA
MMAR_5352|M.marinum_M GLGRSYGDNAQNGGGLVIDMSPLNKIHSISADSKLVDVDAGVNLDQLMKA
MUL_4969|M.ulcerans_Agy99 GLGRSYGDNAQNGGGLVIDMSPLNKIHSISADSTLVDVDAGVNLDQLMKA
Mflv_1178|M.gilvum_PYR-GCK GLGRSYGDNAQNGGGLVIDMSSLDRIHSMDADSRLVDVDGGVNLDQLMRA
Mvan_5627|M.vanbaalenii_PYR-1 GLGRSYGDNAQNGGGLVVDMSVLNRIHSMDSDSHLVDVDGGVNLDQLMRA
MSMEG_6382|M.smegmatis_MC2_155 GLGRSYGDNAQNGGGLVIDMPALNRIHSIDSGTRLVDVDAGVSLDQLMKA
TH_1603|M.thermoresistible__bu GLGRSYGDNAQNGGGLVIDMTPLNRIHRIDAETRLVDLDAGVSLDTLMKA
MAV_0232|M.avium_104 GLGRSYGDNAQNGGGLVIDMTGLNRIHSISADTRLVDVDAGVSLDQLMKA
MAB_0192c|M.abscessus_ATCC_199 GLGRSYGDHACNGGGIVVDMTPLKRVHSISAETAVADVDAGVSLDQLMKA
********:* ****:*:**. *. :* :.: : :.*:*.**.*: **:*
Mb3819|M.bovis_AF2122/97 ALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTA
Rv3790|M.tuberculosis_H37Rv ALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTA
MLBr_00109|M.leprae_Br4923 ALPFGLWIPVLPGTRQVTIGGAIACDIHGKNHHSAGSFGNYVRSMDLLTA
MMAR_5352|M.marinum_M ALPLGLWVPVLPGTRQVTIGGAIACDIHGKNHHSAGSFGNHVRSLDLLTA
MUL_4969|M.ulcerans_Agy99 ALPLGLWVPVLPGTRQVTIGGAIACDIHGKNHHSAGSFGNHVRSLDLLTA
Mflv_1178|M.gilvum_PYR-GCK ALPLGLWVPVLPGTRQVTIGGAIACDIHGKNHHSAGSFGNHVRSIDLLTA
Mvan_5627|M.vanbaalenii_PYR-1 ALPLGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTA
MSMEG_6382|M.smegmatis_MC2_155 ALPHGLWVPVLPGTRQVTVGGAIGCDIHGKNHHSAGSFGNHVRSMELLTA
TH_1603|M.thermoresistible__bu ALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSIDLLTA
MAV_0232|M.avium_104 ALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMELLMA
MAB_0192c|M.abscessus_ATCC_199 ALPFGLWVPVLPGTRQVTVGGAIGSDIHGKNHHSAGSFGNHVLSMDLLMA
*** ***:**********:****..***************:* *::** *
Mb3819|M.bovis_AF2122/97 DGEIRHLTPTG---EDAELFWATVGGNGLTGIIMRATIEMTPTSTAYFIA
Rv3790|M.tuberculosis_H37Rv DGEIRHLTPTG---EDAELFWATVGGNGLTGIIMRATIEMTPTSTAYFIA
MLBr_00109|M.leprae_Br4923 SGEVRRLTPTG---KDSELFWATVGGNGLTGIIMRATIEMMPTETAYFIA
MMAR_5352|M.marinum_M DGEVRHLTPTGTETADTALFWATVGGNGLTGIILRATIEMTPTETAYFIA
MUL_4969|M.ulcerans_Agy99 DGEVRHLTPTGTETADTELFWATVGGNGLTGIILRATIEMTPTETAYFIA
Mflv_1178|M.gilvum_PYR-GCK DGRVRTITPDG---PESPLFWATVGGNGLTGIILRATIEMTPTETAYFIA
Mvan_5627|M.vanbaalenii_PYR-1 DGEVRTLTPSG---PDADLFWATVGGNGLTGIILRATIEMTPTETAYFIA
MSMEG_6382|M.smegmatis_MC2_155 NGEVRHLTPAG---PDSDLFWATVGGNGLTGIILRATIEMTPTETAYFIA
TH_1603|M.thermoresistible__bu DGQIRRLTPDG---DDPELFWATVGGNGLTGIILRATIEMTPTETAYFIA
MAV_0232|M.avium_104 DGTVRTITPDGPDASDAELFWATVGGNGLTGIVLRATIAMTPTETAYFIA
MAB_0192c|M.abscessus_ATCC_199 DGEVHTITPDGP---ASELFWATVGGNGLTGIVVRARIAMTRTETAYFIA
.* :: :** * . **************::** * * *.******
Mb3819|M.bovis_AF2122/97 DGDVTASLDETIALHSDGSEARYTYSSAWFDAISAPPKLGRAAVSRGRLA
Rv3790|M.tuberculosis_H37Rv DGDVTASLDETIALHSDGSEARYTYSSAWFDAISAPPKLGRAAVSRGRLA
MLBr_00109|M.leprae_Br4923 DGDITGSLDETIALHSDGSEADYTYSSAWFDAISASPKLGRAAVSRGCLA
MMAR_5352|M.marinum_M DGDVTASLDETIALHSDGSEGNYTYSSAWFDAISGPPKLGRAAVSRGCLA
MUL_4969|M.ulcerans_Agy99 DGDVTASLDETIALHSDGSGGNYTYSSAWFDAISGPPKLGRAAVSRGCLA
Mflv_1178|M.gilvum_PYR-GCK DGDVTSGLDETIAFHSDGTEDNYTYSSAWFDAISPPPKLGRAAISRGSLA
Mvan_5627|M.vanbaalenii_PYR-1 DGDVTSGLEETIAFHSDGTEDNYTYSSAWFDAISAPPKLGRAVISRGSLA
MSMEG_6382|M.smegmatis_MC2_155 DGDVTGSLDETIAFHSDGSEANYTYSSAWFDAISKPPKLGRAAISRGSLA
TH_1603|M.thermoresistible__bu DGDVTATLDETIALHSDGSEDNYTYSSAWFDAISAPPKLGRAAISRGSLA
MAV_0232|M.avium_104 DGMATKDLDETVAVHLDGSEADYTYSSAWFDLISPPPKLGRAAVSRGSLA
MAB_0192c|M.abscessus_ATCC_199 DGVATRDLDETIAVHQDGTEDNYTYSSAWFDLINPPPKLGRAAVSRGSLA
** * *:**:*.* **: ********* *. .******.:*** **
Mb3819|M.bovis_AF2122/97 TVEQLPAKLRSEPLKFDAPQLLTLPDVFPNGLANKYTFGPIGELWYRKSG
Rv3790|M.tuberculosis_H37Rv TVEQLPAKLRSEPLKFDAPQLLTLPDVFPNGLANKYTFGPIGELWYRKSG
MLBr_00109|M.leprae_Br4923 RLDQLPAKLRRNPLKFHAPQLLTLPDVFPNGLANKYTFMPIGELWYRKSG
MMAR_5352|M.marinum_M TIDQLPTKLQRDPLKFDAPQLLTFPDVFPNGLANKYTFGPIGELWYRKSG
MUL_4969|M.ulcerans_Agy99 TIDQLPTKLQRDPLKFDAPQLLTFPDVFPNGLANKYTFGPIGELWYRKSG
Mflv_1178|M.gilvum_PYR-GCK TVDQLPKKLQKNPLKFDAPQLLTFPDLFPNGLANKYTFGPIGELWYRKSG
Mvan_5627|M.vanbaalenii_PYR-1 TVDQLPRKLQKNPLKFDAPQYFTAPEIFPNGLGNKYTFGPMTEVWYRLGK
MSMEG_6382|M.smegmatis_MC2_155 KLDQLPSKLQKDPLKFDAPQLLTLPDIFPNGLANKFTFMPIGELWYRKSG
TH_1603|M.thermoresistible__bu RLDELPPKLRKNPLKFDAPQLLTFPDIFPNGLANKYTFGPIGELWYRKSG
MAV_0232|M.avium_104 RLDQLPKKLAKNPLKFDAPQLLTVPDVFPVSAMNKLSFMAIGEVYYRLGG
MAB_0192c|M.abscessus_ATCC_199 KLDQLPPKLAKDPLKFSAPQLPGLPDLFPVNFMIKPSLMAIGEAFYRMSG
:::** ** :**** *** *::** . * :: .: * :** .
Mb3819|M.bovis_AF2122/97 TYRGKVQNLTQFYHPLDMFGEWNRAYGPAGFLQYQFVIPTEAVDEFKKII
Rv3790|M.tuberculosis_H37Rv TYRGKVQNLTQFYHPLDMFGEWNRAYGPAGFLQYQFVIPTEAVDEFKKII
MLBr_00109|M.leprae_Br4923 TYRGKIQNLTQFYHPLDMFGEWNRAYGAAGFLQYQFVIPTEAVDKVKRII
MMAR_5352|M.marinum_M TYRGKVQNLTQFYHPLDMFGEWNRAYGPAGFLQYQFVVPTEAVDEFKRII
MUL_4969|M.ulcerans_Agy99 TYRGKVQNLTQFYHPLDMFGEWNRAYGPAGFLQYQFVVPTEAVDEFKRII
Mflv_1178|M.gilvum_PYR-GCK TYRGKVQNLTQFYHPLDMFGEWNRAYGAAGFTQYQFVVPTTAVDEFKAII
Mvan_5627|M.vanbaalenii_PYR-1 TYRGKAQNLTQFYHPLDMVGDWNRAYGSVGFAQYQFVVPTEAVDEFKRIM
MSMEG_6382|M.smegmatis_MC2_155 TYRNKVQNLTQFYHPLDMFGEWNRAYGSAGFLQYQFVVPTEAVEEFKSII
TH_1603|M.thermoresistible__bu TYRNKIQNLTQFYHPLDMFGEWNRAYGPAGFTQYQFVVPTEAVDEFKAIL
MAV_0232|M.avium_104 TYTGKIMNLSQFYHMLDLVSGWNNAYGPRGFAQHQFLVPPDAMDEFKAII
MAB_0192c|M.abscessus_ATCC_199 NYQGKIVNLTQFYHMLDITTGWQYAYGPAGFAQHQFLVPPDALEEFKGII
.* .* **:**** **: *: ***. ** *:**::*. *:::.* *:
Mb3819|M.bovis_AF2122/97 GVIQASGHYSFLNVFKLFGPRNQAPLSFPIPGWNICVDFPIKDGLGKFVS
Rv3790|M.tuberculosis_H37Rv GVIQASGHYSFLNVFKLFGPRNQAPLSFPIPGWNICVDFPIKDGLGKFVS
MLBr_00109|M.leprae_Br4923 GDMQGSGHYSFLNVFKLFGPGNQAPLSFPIPGWNICVDFPIKSGLNEFVN
MMAR_5352|M.marinum_M GDIQASGHYSFLNVFKLFGAGNQAPLSFPIPGWNICVDFPIKAGLNEFVS
MUL_4969|M.ulcerans_Agy99 GDIQASGHYSFLNVFKLFGAGNQAPLSFPIPGWNICVDFPIKAGLNEFVS
Mflv_1178|M.gilvum_PYR-GCK VDIQRSGFYSFLNVFKLFGPGNQAPLSFPIPGWNVCVDFPITAGLNEFLN
Mvan_5627|M.vanbaalenii_PYR-1 YDIQRSGHYSFLNVFKLFGPGNDAPLSFPIPGWNVCVDFQINPGLNEFLN
MSMEG_6382|M.smegmatis_MC2_155 VDIQRSGHYSFLNVFKLFGPGNQAPLSFPIPGWNVCVDFPIKAGLHEFVT
TH_1603|M.thermoresistible__bu VDIQRSGHYSFLNVFKLFGPGNKAPLSFPIPGWNVCVDFPVKPGLNEFLT
MAV_0232|M.avium_104 RWIQTRGHYSALNVFKLFGPGNRAPLSFPMAGWNVAMDFPNKPGVNEFLN
MAB_0192c|M.abscessus_ATCC_199 RWIQTQGQYSALNVFKLFGPGNKAPLSFPMKGWNVAMDFPNKPGVNEFLN
:* * ** ********. * ******: ***:.:** . *: :*:.
Mb3819|M.bovis_AF2122/97 ELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRVDEWISVRRKVDPLRVFA
Rv3790|M.tuberculosis_H37Rv ELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRVDEWISVRRKVDPLRVFA
MLBr_00109|M.leprae_Br4923 KLDRRVMELGGRLYTAKDSRTTADTFHAMYPRIDEWIAVRRKVDPLRVFS
MMAR_5352|M.marinum_M ELDRRVMEFGGRLYTAKDSRTTAETFHAMYPRIDEWIAVRRKVDPCGVFA
MUL_4969|M.ulcerans_Agy99 ELDRRVMEFGGRLYTAKDSRTTAETFHAMYPRIDEWIAVRRKVDPCGVFA
Mflv_1178|M.gilvum_PYR-GCK GLDKRVLQFGGRLYTAKDSRTTAETFHAMYPRIDEWIAVRRNVDPDGVFA
Mvan_5627|M.vanbaalenii_PYR-1 GLDKRVLEFGGRLYTAKDSRTTAETFHAMYPRIDEWIALRRKVDPDGVFA
MSMEG_6382|M.smegmatis_MC2_155 ELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRIDEWIRIRRSVDPDGVFA
TH_1603|M.thermoresistible__bu GLDRRVLEFGGRLYTAKDSRTTAETFHAMYPRIDEWIAVRRRVDPEGIFA
MAV_0232|M.avium_104 ELDRRVLQFGGRVYTAKDSRTNAETFHAMYPRIDEWIAVRRKVDPTGVFA
MAB_0192c|M.abscessus_ATCC_199 ELDNRAMEFGGRVYTAKDSRVSAEKFHRMYPRVDEWIATRRKADPHGVFA
**.*.:::***:*******..*:.** ****:**** ** .** :*:
Mb3819|M.bovis_AF2122/97 SDMARRLELL
Rv3790|M.tuberculosis_H37Rv SDMARRLELL
MLBr_00109|M.leprae_Br4923 SDMARRLELL
MMAR_5352|M.marinum_M SDMARRLELL
MUL_4969|M.ulcerans_Agy99 SDMARRLELL
Mflv_1178|M.gilvum_PYR-GCK SDMARRLELL
Mvan_5627|M.vanbaalenii_PYR-1 SDMARRLELL
MSMEG_6382|M.smegmatis_MC2_155 SDMARRLQLL
TH_1603|M.thermoresistible__bu SDMARRLELL
MAV_0232|M.avium_104 SDMARRLELL
MAB_0192c|M.abscessus_ATCC_199 SDMARRLELL
*******:**