For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_4935 (-)

annotation: MutT/NUDIX family protein
coordinates: 5044671 - 5045486
length: 271

VSDSSGGSRTGGSSDEPGSNPASARGRGSRRGRRNRSQGRAQGRAQGANTPAASPAAGAPAAPNGANTAA
GKGRGRVKGRAAGTSLRTVRETSAGGLVIAGIDGPKDGQVAALIGRTDRRGRMLWSLPKGHIEQGETAEQ
TAIREVAEETGIRGTVLAALGSIDYWFVTEGRRVHKTVHHYLMRSLGGELSDDDVEVTEVAWVPLGELPT
RLAYADERRLAEVAGDLIDKLHTEGPAALPPLPPSAPRRRPQTHSSTHRTPGRRSGRGQQQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4935--100% (271)MutT/NUDIX family protein
M. abscessus ATCC 19977MAB_3291-3e-1137.50% (96) MutT/NUDIX hydrolase
M. abscessus ATCC 19977MAB_2365-2e-0729.41% (170) MutT/nudix family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3938-3e-8967.45% (255) hypothetical protein Mb3938
M. gilvum PYR-GCKMflv_0844-3e-9068.38% (272) NUDIX hydrolase
M. tuberculosis H37RvRv3908-3e-8967.45% (255) hypothetical protein Rv3908
M. leprae Br4923MLBr_02698-1e-8267.62% (244) hypothetical protein MLBr_02698
M. marinum MMMAR_5472-3e-8969.96% (243) hypothetical protein MMAR_5472
M. avium 104MAV_5296-3e-8669.20% (237) MutT/nudix family protein
M. smegmatis MC2 155MSMEG_6927-4e-9064.46% (287) MutT/nudix family protein
M. thermoresistible (build 8)TH_0513-2e-8485.39% (178) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_5061-2e-9070.90% (244) hypothetical protein MUL_5061
M. vanbaalenii PYR-1Mvan_6062-7e-8967.18% (262) NUDIX hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_02698|M.leprae_Br4923          -----MP--AIIAWVSD--GEQAKPRRRRKRRRGRD--------ATRSAE
MAV_5296|M.avium_104                --------------MSD--GEQGKPRRRRGRRRGRG--------AATSSE
Mb3938|M.bovis_AF2122/97            --------------MSD--GEQAKSRRRRGRRRGRR--------AAATAE
Rv3908|M.tuberculosis_H37Rv         --------------MSD--GEQAKSRRRRGRRRGRR--------AAATAE
MMAR_5472|M.marinum_M               --------------MSE--GEQAKPRRRRGRRRGRG--------AARSAE
MUL_5061|M.ulcerans_Agy99           --------------MSE--GEQAKPRRRRGRRRGRG--------AARSAE
Mflv_0844|M.gilvum_PYR-GCK          MRSGRVPPATIIAGVSD--GEQAKPRRRRGRRRGRR--------AAGPPE
Mvan_6062|M.vanbaalenii_PYR-1       -----MP--ATIAWVSD--GEQAKPRRRRGRRRGRR--------AAGPPE
MSMEG_6927|M.smegmatis_MC2_155      --------------MSD--GEQAKPRRRRGRRRGHRRAQRAAGPPAAGAE
TH_0513|M.thermoresistible__bu      --------------------------------------------------
MAB_4935|M.abscessus_ATCC_1997      --MSDSSGGSRTGGSSDEPGSNPASARGRGSRRGRRNR------SQGRAQ
                                                                                      

MLBr_02698|M.leprae_Br4923          NHTD--------------RQVANDATAT----------------------
MAV_5296|M.avium_104                KQTN--------------GQLTGDSTAT----------------------
Mb3938|M.bovis_AF2122/97            NHMD--------------AQPAGDATPTPA--------------------
Rv3908|M.tuberculosis_H37Rv         NHMD--------------AQPAGDATPTPA--------------------
MMAR_5472|M.marinum_M               NHTD--------------KAESTDPNPAP---------------------
MUL_5061|M.ulcerans_Agy99           NHTD--------------NAGSPDPNPAP---------------------
Mflv_0844|M.gilvum_PYR-GCK          AGTDQAPGARQQN-SGARQQSSGAGTADQA--------------------
Mvan_6062|M.vanbaalenii_PYR-1       ALPDQAADHR--------QQAPPAGTAGQA--------------------
MSMEG_6927|M.smegmatis_MC2_155      HHTEPAADARTESRADTRSDTSSAPTPATQPGEKKPGPGRGSRAGAAKPT
TH_0513|M.thermoresistible__bu      --------------------------------------------------
MAB_4935|M.abscessus_ATCC_1997      GRAQGAN-------TPAASPAAGAPAAPNG------------------AN
                                                                                      

MLBr_02698|M.leprae_Br4923          ---KPRRSHSPHRA-PEQLRTVHETSAGGLVIYGIDGPRDAQVAALIGRI
MAV_5296|M.avium_104                ---KPRRSRAARRA-PDRLRTVHETSAGGLVIDGLDGPRESQVAALIGRI
Mb3938|M.bovis_AF2122/97            -TAKRSRSRSPRRG-STRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRV
Rv3908|M.tuberculosis_H37Rv         -TAKRSRSRSPRRG-STRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRV
MMAR_5472|M.marinum_M               --TKGRRPRLPRRGRPDRLRTVHETSAGGLVIDGIDGPRDEQVAALIGRI
MUL_5061|M.ulcerans_Agy99           --TKGRRPRLPRRGRPDRLRTVHETSAGGLVIDGIDGPRDAQVAALIGRI
Mflv_0844|M.gilvum_PYR-GCK          -GQPPKPQRTRTRRPQERLRTVHETSAGGLVIDGLDGPKDSQVAALIGRV
Mvan_6062|M.vanbaalenii_PYR-1       -RQTPKPQRTRTRRPPERLRTVHETSAGGLVIDGIDGPKDGQVAALIGRI
MSMEG_6927|M.smegmatis_MC2_155      PKDQPKQRKNRPRRPPDRLRTVHETSAGGLVIDGIDGPKDSQVAALIGRL
TH_0513|M.thermoresistible__bu      ------------------LRTVHETSAGGLVIDGLDGPKEKQVAALIGRL
MAB_4935|M.abscessus_ATCC_1997      TAAGKGRGRVKGRAAGTSLRTVRETSAGGLVIAGIDGPKDGQVAALIGRT
                                                      :***:********* *:***:: ******** 

MLBr_02698|M.leprae_Br4923          DRRGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGSVLAALGQIDYWF
MAV_5296|M.avium_104                DRRGRMLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWF
Mb3938|M.bovis_AF2122/97            DRRGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWF
Rv3908|M.tuberculosis_H37Rv         DRRGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWF
MMAR_5472|M.marinum_M               DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGISGGVLAALGRIDYWF
MUL_5061|M.ulcerans_Agy99           DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIRGGVLAALGRIDYWF
Mflv_0844|M.gilvum_PYR-GCK          DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIEGSVLAALGSIDYWF
Mvan_6062|M.vanbaalenii_PYR-1       DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIQGSVLAALGSIDYWF
MSMEG_6927|M.smegmatis_MC2_155      DRRGRMLWSLPKGHIELGETAEQTAIREVAEETGIQGSVLAALGSIDYWF
TH_0513|M.thermoresistible__bu      DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGVQGAVLAALGSIDYWF
MAB_4935|M.abscessus_ATCC_1997      DRRGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGTVLAALGSIDYWF
                                    *****:********** *****************: * ****** *****

MLBr_02698|M.leprae_Br4923          VTDDCRVHKTVHHYLMRFSGGELSDDDLEVTEVAWVPIRELPSRLAYADE
MAV_5296|M.avium_104                VTDGRRVHKTVHHYLMRFSGGELSDEDLEVAEVAWVPMRELPSRLAYADE
Mb3938|M.bovis_AF2122/97            VTDGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADE
Rv3908|M.tuberculosis_H37Rv         VTDGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADE
MMAR_5472|M.marinum_M               VTDGRRVHKTVHHYLMRFLGGELSDNDLEVTEVAWVPIPELPSRLAYADE
MUL_5061|M.ulcerans_Agy99           VTDGRRVHKTVHHYLMRFLGGELSDNDLEVTEVAWVPIPELPSRLAYADE
Mflv_0844|M.gilvum_PYR-GCK          VTEGRRVHKTVHHYLMRFLGGELSDEDVEVTEVAWVPLKDLPSRLAYADE
Mvan_6062|M.vanbaalenii_PYR-1       VTEGRRVHKTVHHYLMRFSGGELSDEDVEVTEVAWVPVKDLPSRLAYADE
MSMEG_6927|M.smegmatis_MC2_155      VTEGRRVHKTVHHYLMRFLGGELSDDDVEVTEVAWVPLRELPSRLAYADE
TH_0513|M.thermoresistible__bu      VTEGRRVHKTVHHYLMRFLGGELSDDDVEVSEVAWVPLSELPTRLAYADE
MAB_4935|M.abscessus_ATCC_1997      VTEGRRVHKTVHHYLMRSLGGELSDDDVEVTEVAWVPLGELPTRLAYADE
                                    **:. ************  ******:*:**:******: :**:*******

MLBr_02698|M.leprae_Br4923          RRLAEVAYELINKLQTGGPAALPPLPPSLPRRQSQTHFRT-----RHSNN
MAV_5296|M.avium_104                RRLARVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRTRHSETRHSDK
Mb3938|M.bovis_AF2122/97            RRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRA-----RHADD
Rv3908|M.tuberculosis_H37Rv         RRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRA-----RHADD
MMAR_5472|M.marinum_M               RRLAEVADELIDKLQTDGPTALPPLPPSAPRRRPQTHSRT-----RHAAE
MUL_5061|M.ulcerans_Agy99           RRLAEVADELIDKLQTDGPTALPPLPPSAPRRRPQTHSRT-----RHAAE
Mflv_0844|M.gilvum_PYR-GCK          RKLAEVADELIDKLHTEGPGALPPLPHSAPRRRGQTHSHTR----KHRSD
Mvan_6062|M.vanbaalenii_PYR-1       RRLAEVADELIDKLHTDGPGALPPLPRTTPRRRGQTHSHTR----RHRPD
MSMEG_6927|M.smegmatis_MC2_155      RRLAEVAGELIDKLHTGGPAALPPLPHSAPRRRAQTHSHT-----RNRRD
TH_0513|M.thermoresistible__bu      RRLAEVAGELIDTLQTHGPQALPPLPQMAPRRRPQTHSRTRSS--RRRDD
MAB_4935|M.abscessus_ATCC_1997      RRLAEVAGDLIDKLHTEGPAALPPLPPSAPRRRPQTHSST------HRTP
                                    *:**.** :**:.*:: ** ******   ***: ***  :      .   

MLBr_02698|M.leprae_Br4923          -SANSR---------------KNGHGQGP
MAV_5296|M.avium_104                -PATGR---------------KNGHGPGP
Mb3938|M.bovis_AF2122/97            -SAPGQ---------------HNGPGPGP
Rv3908|M.tuberculosis_H37Rv         -SAPGQ---------------HNGPGPGP
MMAR_5472|M.marinum_M               GSPPGR---------------KNGHGPGP
MUL_5061|M.ulcerans_Agy99           GSPPGR---------------KNGHGPGP
Mflv_0844|M.gilvum_PYR-GCK          PSAQQQP-----------GRRTNGCGQGP
Mvan_6062|M.vanbaalenii_PYR-1       PTAQPQP-----------GRRTNGCGQGP
MSMEG_6927|M.smegmatis_MC2_155      DTAQPQA-----------RRRTNGCGQGP
TH_0513|M.thermoresistible__bu      SAAHSRGEGRERGAANSSGRRTNGCGKGP
MAB_4935|M.abscessus_ATCC_1997      ----GR---------------RSGRGQQQ
                                         :                .* *