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VSDSSGGSRTGGSSDEPGSNPASARGRGSRRGRRNRSQGRAQGRAQGANTPAASPAAGAPAAPNGANTAA GKGRGRVKGRAAGTSLRTVRETSAGGLVIAGIDGPKDGQVAALIGRTDRRGRMLWSLPKGHIEQGETAEQ TAIREVAEETGIRGTVLAALGSIDYWFVTEGRRVHKTVHHYLMRSLGGELSDDDVEVTEVAWVPLGELPT RLAYADERRLAEVAGDLIDKLHTEGPAALPPLPPSAPRRRPQTHSSTHRTPGRRSGRGQQQ
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4935 | - | - | 100% (271) | MutT/NUDIX family protein |
M. abscessus ATCC 19977 | MAB_3291 | - | 3e-11 | 37.50% (96) | MutT/NUDIX hydrolase |
M. abscessus ATCC 19977 | MAB_2365 | - | 2e-07 | 29.41% (170) | MutT/nudix family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3938 | - | 3e-89 | 67.45% (255) | hypothetical protein Mb3938 |
M. gilvum PYR-GCK | Mflv_0844 | - | 3e-90 | 68.38% (272) | NUDIX hydrolase |
M. tuberculosis H37Rv | Rv3908 | - | 3e-89 | 67.45% (255) | hypothetical protein Rv3908 |
M. leprae Br4923 | MLBr_02698 | - | 1e-82 | 67.62% (244) | hypothetical protein MLBr_02698 |
M. marinum M | MMAR_5472 | - | 3e-89 | 69.96% (243) | hypothetical protein MMAR_5472 |
M. avium 104 | MAV_5296 | - | 3e-86 | 69.20% (237) | MutT/nudix family protein |
M. smegmatis MC2 155 | MSMEG_6927 | - | 4e-90 | 64.46% (287) | MutT/nudix family protein |
M. thermoresistible (build 8) | TH_0513 | - | 2e-84 | 85.39% (178) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_5061 | - | 2e-90 | 70.90% (244) | hypothetical protein MUL_5061 |
M. vanbaalenii PYR-1 | Mvan_6062 | - | 7e-89 | 67.18% (262) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_02698|M.leprae_Br4923 -----MP--AIIAWVSD--GEQAKPRRRRKRRRGRD--------ATRSAE MAV_5296|M.avium_104 --------------MSD--GEQGKPRRRRGRRRGRG--------AATSSE Mb3938|M.bovis_AF2122/97 --------------MSD--GEQAKSRRRRGRRRGRR--------AAATAE Rv3908|M.tuberculosis_H37Rv --------------MSD--GEQAKSRRRRGRRRGRR--------AAATAE MMAR_5472|M.marinum_M --------------MSE--GEQAKPRRRRGRRRGRG--------AARSAE MUL_5061|M.ulcerans_Agy99 --------------MSE--GEQAKPRRRRGRRRGRG--------AARSAE Mflv_0844|M.gilvum_PYR-GCK MRSGRVPPATIIAGVSD--GEQAKPRRRRGRRRGRR--------AAGPPE Mvan_6062|M.vanbaalenii_PYR-1 -----MP--ATIAWVSD--GEQAKPRRRRGRRRGRR--------AAGPPE MSMEG_6927|M.smegmatis_MC2_155 --------------MSD--GEQAKPRRRRGRRRGHRRAQRAAGPPAAGAE TH_0513|M.thermoresistible__bu -------------------------------------------------- MAB_4935|M.abscessus_ATCC_1997 --MSDSSGGSRTGGSSDEPGSNPASARGRGSRRGRRNR------SQGRAQ MLBr_02698|M.leprae_Br4923 NHTD--------------RQVANDATAT---------------------- MAV_5296|M.avium_104 KQTN--------------GQLTGDSTAT---------------------- Mb3938|M.bovis_AF2122/97 NHMD--------------AQPAGDATPTPA-------------------- Rv3908|M.tuberculosis_H37Rv NHMD--------------AQPAGDATPTPA-------------------- MMAR_5472|M.marinum_M NHTD--------------KAESTDPNPAP--------------------- MUL_5061|M.ulcerans_Agy99 NHTD--------------NAGSPDPNPAP--------------------- Mflv_0844|M.gilvum_PYR-GCK AGTDQAPGARQQN-SGARQQSSGAGTADQA-------------------- Mvan_6062|M.vanbaalenii_PYR-1 ALPDQAADHR--------QQAPPAGTAGQA-------------------- MSMEG_6927|M.smegmatis_MC2_155 HHTEPAADARTESRADTRSDTSSAPTPATQPGEKKPGPGRGSRAGAAKPT TH_0513|M.thermoresistible__bu -------------------------------------------------- MAB_4935|M.abscessus_ATCC_1997 GRAQGAN-------TPAASPAAGAPAAPNG------------------AN MLBr_02698|M.leprae_Br4923 ---KPRRSHSPHRA-PEQLRTVHETSAGGLVIYGIDGPRDAQVAALIGRI MAV_5296|M.avium_104 ---KPRRSRAARRA-PDRLRTVHETSAGGLVIDGLDGPRESQVAALIGRI Mb3938|M.bovis_AF2122/97 -TAKRSRSRSPRRG-STRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRV Rv3908|M.tuberculosis_H37Rv -TAKRSRSRSPRRG-STRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRV MMAR_5472|M.marinum_M --TKGRRPRLPRRGRPDRLRTVHETSAGGLVIDGIDGPRDEQVAALIGRI MUL_5061|M.ulcerans_Agy99 --TKGRRPRLPRRGRPDRLRTVHETSAGGLVIDGIDGPRDAQVAALIGRI Mflv_0844|M.gilvum_PYR-GCK -GQPPKPQRTRTRRPQERLRTVHETSAGGLVIDGLDGPKDSQVAALIGRV Mvan_6062|M.vanbaalenii_PYR-1 -RQTPKPQRTRTRRPPERLRTVHETSAGGLVIDGIDGPKDGQVAALIGRI MSMEG_6927|M.smegmatis_MC2_155 PKDQPKQRKNRPRRPPDRLRTVHETSAGGLVIDGIDGPKDSQVAALIGRL TH_0513|M.thermoresistible__bu ------------------LRTVHETSAGGLVIDGLDGPKEKQVAALIGRL MAB_4935|M.abscessus_ATCC_1997 TAAGKGRGRVKGRAAGTSLRTVRETSAGGLVIAGIDGPKDGQVAALIGRT :***:********* *:***:: ******** MLBr_02698|M.leprae_Br4923 DRRGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGSVLAALGQIDYWF MAV_5296|M.avium_104 DRRGRMLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWF Mb3938|M.bovis_AF2122/97 DRRGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWF Rv3908|M.tuberculosis_H37Rv DRRGRLLWSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWF MMAR_5472|M.marinum_M DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGISGGVLAALGRIDYWF MUL_5061|M.ulcerans_Agy99 DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIRGGVLAALGRIDYWF Mflv_0844|M.gilvum_PYR-GCK DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIEGSVLAALGSIDYWF Mvan_6062|M.vanbaalenii_PYR-1 DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIQGSVLAALGSIDYWF MSMEG_6927|M.smegmatis_MC2_155 DRRGRMLWSLPKGHIELGETAEQTAIREVAEETGIQGSVLAALGSIDYWF TH_0513|M.thermoresistible__bu DRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGVQGAVLAALGSIDYWF MAB_4935|M.abscessus_ATCC_1997 DRRGRMLWSLPKGHIEQGETAEQTAIREVAEETGIRGTVLAALGSIDYWF *****:********** *****************: * ****** ***** MLBr_02698|M.leprae_Br4923 VTDDCRVHKTVHHYLMRFSGGELSDDDLEVTEVAWVPIRELPSRLAYADE MAV_5296|M.avium_104 VTDGRRVHKTVHHYLMRFSGGELSDEDLEVAEVAWVPMRELPSRLAYADE Mb3938|M.bovis_AF2122/97 VTDGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADE Rv3908|M.tuberculosis_H37Rv VTDGRRVHKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADE MMAR_5472|M.marinum_M VTDGRRVHKTVHHYLMRFLGGELSDNDLEVTEVAWVPIPELPSRLAYADE MUL_5061|M.ulcerans_Agy99 VTDGRRVHKTVHHYLMRFLGGELSDNDLEVTEVAWVPIPELPSRLAYADE Mflv_0844|M.gilvum_PYR-GCK VTEGRRVHKTVHHYLMRFLGGELSDEDVEVTEVAWVPLKDLPSRLAYADE Mvan_6062|M.vanbaalenii_PYR-1 VTEGRRVHKTVHHYLMRFSGGELSDEDVEVTEVAWVPVKDLPSRLAYADE MSMEG_6927|M.smegmatis_MC2_155 VTEGRRVHKTVHHYLMRFLGGELSDDDVEVTEVAWVPLRELPSRLAYADE TH_0513|M.thermoresistible__bu VTEGRRVHKTVHHYLMRFLGGELSDDDVEVSEVAWVPLSELPTRLAYADE MAB_4935|M.abscessus_ATCC_1997 VTEGRRVHKTVHHYLMRSLGGELSDDDVEVTEVAWVPLGELPTRLAYADE **:. ************ ******:*:**:******: :**:******* MLBr_02698|M.leprae_Br4923 RRLAEVAYELINKLQTGGPAALPPLPPSLPRRQSQTHFRT-----RHSNN MAV_5296|M.avium_104 RRLARVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRTRHSETRHSDK Mb3938|M.bovis_AF2122/97 RRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRA-----RHADD Rv3908|M.tuberculosis_H37Rv RRLAEVADELIDKLQSDGPAALPPLPPSSPRRRPQTHSRA-----RHADD MMAR_5472|M.marinum_M RRLAEVADELIDKLQTDGPTALPPLPPSAPRRRPQTHSRT-----RHAAE MUL_5061|M.ulcerans_Agy99 RRLAEVADELIDKLQTDGPTALPPLPPSAPRRRPQTHSRT-----RHAAE Mflv_0844|M.gilvum_PYR-GCK RKLAEVADELIDKLHTEGPGALPPLPHSAPRRRGQTHSHTR----KHRSD Mvan_6062|M.vanbaalenii_PYR-1 RRLAEVADELIDKLHTDGPGALPPLPRTTPRRRGQTHSHTR----RHRPD MSMEG_6927|M.smegmatis_MC2_155 RRLAEVAGELIDKLHTGGPAALPPLPHSAPRRRAQTHSHT-----RNRRD TH_0513|M.thermoresistible__bu RRLAEVAGELIDTLQTHGPQALPPLPQMAPRRRPQTHSRTRSS--RRRDD MAB_4935|M.abscessus_ATCC_1997 RRLAEVAGDLIDKLHTEGPAALPPLPPSAPRRRPQTHSST------HRTP *:**.** :**:.*:: ** ****** ***: *** : . MLBr_02698|M.leprae_Br4923 -SANSR---------------KNGHGQGP MAV_5296|M.avium_104 -PATGR---------------KNGHGPGP Mb3938|M.bovis_AF2122/97 -SAPGQ---------------HNGPGPGP Rv3908|M.tuberculosis_H37Rv -SAPGQ---------------HNGPGPGP MMAR_5472|M.marinum_M GSPPGR---------------KNGHGPGP MUL_5061|M.ulcerans_Agy99 GSPPGR---------------KNGHGPGP Mflv_0844|M.gilvum_PYR-GCK PSAQQQP-----------GRRTNGCGQGP Mvan_6062|M.vanbaalenii_PYR-1 PTAQPQP-----------GRRTNGCGQGP MSMEG_6927|M.smegmatis_MC2_155 DTAQPQA-----------RRRTNGCGQGP TH_0513|M.thermoresistible__bu SAAHSRGEGRERGAANSSGRRTNGCGKGP MAB_4935|M.abscessus_ATCC_1997 ----GR---------------RSGRGQQQ : .* *