For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RGAPVILLSVTVLLSSCTQAIAGDATAPVKAEKLYPVLPPRQAELADRLLSASDVRAAAGLPEVKTIPPV ETVLSTANTVSDCAYGYSLATRQQYLSFGAARIQAYAHTVDKMRKHTVGTALIVFETASSASQQFEQFAQ RMSRCDGAHGTTSVGGASENWTLKILHSGQDEVNWTRTTDHSPWSCRLVARQRANYVASVMFCRIDPEDD KTEAMFTLLLDKLAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4914c | - | - | 100% (226) | hypothetical protein MAB_4914c |
| M. abscessus ATCC 19977 | MAB_4915c | - | 6e-38 | 38.25% (217) | hypothetical protein MAB_4915c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1297c | pknH | 9e-06 | 23.33% (180) | transmembrane serine/threonine-protein kinase H |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3576 | lppH | 3e-06 | 23.22% (211) | lipoprotein LppH |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1417 | - | 2e-05 | 23.37% (184) | serine/threonine-protein kinase PknE |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3555 | - | 6e-07 | 23.08% (221) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3880 | - | 2e-07 | 21.97% (223) | hypothetical protein Mvan_3880 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1297c|M.bovis_AF2122/97 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAE
MAV_1417|M.avium_104 MSDERSSKVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLNES
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_4914c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 FSKDPVFRERMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTD
MAV_1417|M.avium_104 FSSDPVFRERMKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTD
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_4914c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 LDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRD
MAV_1417|M.avium_104 LDSVLKRFGPLPPPRAVAIITQIASALDAAHAAGVMHRDVKPQNILVTRD
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_4914c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYA
MAV_1417|M.avium_104 DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSDAEVTYRADIYA
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_4914c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 LACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVV
MAV_1417|M.avium_104 LACVLFECLTGSAPYRADSAGVLVSAHVMDPIPAPSARRPGVPKAFDAVI
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_4914c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPGT-
MAV_1417|M.avium_104 ARGMAKKPEDRYASAGDLALAAKEALSTPDQDRAATILRRSQEAALPAAG
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv ------------------------------------------------MG
TH_3555|M.thermoresistible__bu ---------------------------------------------MTKLT
MAB_4914c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ----AAVTAQPPTMPTVTPPPIQAAPTGQPSWAPNSGPMPASGPTPTPQY
MAV_1417|M.avium_104 QRDAGASTVLAPPPAVNTRQPGSAASQAGRGWTPESGPIPAAG-QPGPPY
Mvan_3880|M.vanbaalenii_PYR-1 ----MALAGLAVSLWATACTSTVDGTAVRPDAAPSAVAG-----------
Rv3576|M.tuberculosis_H37Rv KQLAALAALVGACMLAAGCTNVVDGTAVAADKSGPLHQD-----------
TH_3555|M.thermoresistible__bu RRILGGCAAAVVVLTGAACTHSVEGSAVYAPEVPRDDLP-----------
MAB_4914c|M.abscessus_ATCC_199 -MRGAPVILLSVTVLLSSCTQAIAGDATAPVKAEKLYPVL----------
.
Mb1297c|M.bovis_AF2122/97 YQGG--GWGAPPS--GGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAIG
MAV_1417|M.avium_104 YQGGNANWAAAPAQFAGPPPWGRPPPKRRVWPIVA-AVVAVLVVIAGGVG
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_4914c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 IWIANRPKPVQP-PQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSM
MAV_1417|M.avium_104 VWLVIRPKPEPPQAAPLTSDRLGALLLSASEVNAVMGSSTMEPGKPITAT
Mvan_3880|M.vanbaalenii_PYR-1 ---------------VLTERDLDAVLLDSAEIAALLNSPDIEVTDEIDEM
Rv3576|M.tuberculosis_H37Rv ---------------PIPVSALEGLLLDLSQINAALGATSMKVWFNAKAM
TH_3555|M.thermoresistible__bu ---------------LVKIAELRDLIPTADEARTVVEAPNLIYLLAYTKP
MAB_4914c|M.abscessus_ATCC_199 ---------------PPRQAELADRLLSASDVRAAAGLPEVKTIPPVETV
* : : : . :
Mb1297c|M.bovis_AF2122/97 DSSP-VTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNY---EH
MAV_1417|M.avium_104 DSSS-VTVSVPDCQGALYTTQDPVYAGSGYSAVNGLVSSEPGDNY---DH
Mvan_3880|M.vanbaalenii_PYR-1 TDTS-ADVSNPECLGALYTAEDPVYESTGYTAVLTRLASEPGDDN---EH
Rv3576|M.tuberculosis_H37Rv WDWS-KSVADKNCLAIDGPAQEKVYAGTGWTAMRGQRLDDSIDDSKKRDH
TH_3555|M.thermoresistible__bu DSLPPDMLSEPECASAVIPNDASAYRGSGYAAVYGRLADDLRSHR-----
MAB_4914c|M.abscessus_ATCC_199 LSTA-NTVSDCAYGYSLATRQQYLSFGAARIQAYAHTVDKMRKHT-----
. . :: . : .:. .. ..
Mb1297c|M.bovis_AF2122/97 WVNQAVVAFPTADKARAFVQTSADKWKNCAG-KTVTVTNKAKTYRWTFAD
MAV_1417|M.avium_104 WVNQAVVLFPSADKAKSFLQTSLQKWKGCAG-QTVTVTNKSKTYRWTFAQ
Mvan_3880|M.vanbaalenii_PYR-1 WVEESAVLVPTAEDAEQFVERSAREWDDCAG-RQVSISDGEEWFDWELDA
Rv3576|M.tuberculosis_H37Rv YAIQAVVGFPTAHDAEEFYSSSVQSWSSCSNRRFVEVTPGQDDAAWTVAD
TH_3555|M.thermoresistible__bu -ISTGVAAFAGAQEAHEWVTQQVDRWRDCTD-RTLTISLNGQELQWKTSG
MAB_4914c|M.abscessus_ATCC_199 -VGTALIVFETASSASQQFEQFAQRMSRCDG-AHGTTSVGGASENWTLKI
. . * .* * . : *
Mb1297c|M.bovis_AF2122/97 VKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVDVNACGYQITNQAGQ-
MAV_1417|M.avium_104 VQGAPPKITLMDTQEGADGWECQRALSVANNVIVDINACGYRITDQGDQ-
Mvan_3880|M.vanbaalenii_PYR-1 VVRDGGMVSQQSTILDSIDWQCQHTVVSVSNLIIEASVCAERIHDEATT-
Rv3576|M.tuberculosis_H37Rv VVNDNGMLSSSQVQEGGDGWTCQRALTARNNVTIDIVTCAYSQPDLVAIG
TH_3555|M.thermoresistible__bu PTRAEGVHVLLRRQEG-TDYACSRGVAARSNVAADVLVCGRNPEAVNPQA
MAB_4914c|M.abscessus_ATCC_199 LHSGQDEVN-WTRTTDHSPWSCRLVARQRANYVASVMFCRIDPEDDKTEA
. : * * . *
Mb1297c|M.bovis_AF2122/97 --IAAKIVDKVNKE--
MAV_1417|M.avium_104 --IADKIVAKIDNE--
Mvan_3880|M.vanbaalenii_PYR-1 --VVAEMIAKASARTR
Rv3576|M.tuberculosis_H37Rv --IANQIAAKVAKQ--
TH_3555|M.thermoresistible__bu GKLANLMLSKIGD---
MAB_4914c|M.abscessus_ATCC_199 --MFTLLLDKLAR---
: : *