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SIEARHTEGAAKLSEHRAGAAPSRGAIMLVDTDPQIAAGLSEQAAQIGISTLWCRDGADALLHIGAEPPD VLVLAAHTDIINAAQITAAVRGRWQLPILIGAAPATDLIARKALAAGASAVITRPYDINAISPFVLGSEE QPGSGPAVYIAGPIQVDRRGHETRVRDRDVQLTVRELELLVFLIEQHGRVASSEEISRAVWGRPSDTNTV AVHVRRLREKLGDDPEHGEYIRTIRGAGYRLAPSISS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4848c | - | - | 100% (248) | putative response regulator |
| M. abscessus ATCC 19977 | MAB_4047c | - | 7e-22 | 27.23% (224) | sensory transduction protein RegX3 |
| M. abscessus ATCC 19977 | MAB_3250c | - | 4e-20 | 26.61% (218) | transcriptional regulatory protein KdpE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0501 | regX3 | 3e-20 | 25.11% (223) | two component sensory transduction protein RegX3 |
| M. gilvum PYR-GCK | Mflv_0082 | - | 6e-21 | 25.89% (224) | two component transcriptional regulator |
| M. tuberculosis H37Rv | Rv0491 | regX3 | 3e-20 | 25.11% (223) | two component sensory transduction protein RegX3 |
| M. leprae Br4923 | MLBr_00773 | mtrA | 3e-19 | 27.80% (223) | putative two-component response regulator |
| M. marinum M | MMAR_0816 | regX3 | 6e-20 | 25.11% (223) | two-component sensory transduction protein RegX3 |
| M. avium 104 | MAV_4660 | - | 3e-20 | 25.11% (223) | DNA-binding response regulator |
| M. smegmatis MC2 155 | MSMEG_1874 | mtrA | 5e-21 | 28.25% (223) | DNA-binding response regulator MtrA |
| M. thermoresistible (build 8) | TH_4312 | - | 8e-22 | 27.23% (224) | PUTATIVE two component transcriptional regulator, winged helix |
| M. ulcerans Agy99 | MUL_4560 | regX3 | 4e-20 | 25.11% (223) | two component sensory transduction protein RegX3 |
| M. vanbaalenii PYR-1 | Mvan_0831 | - | 1e-21 | 26.79% (224) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0501|M.bovis_AF2122/97 -----------------------MTS-VLIVEDEESLADPLAFLLRKEGF
Rv0491|M.tuberculosis_H37Rv -----------------------MTS-VLIVEDEESLADPLAFLLRKEGF
MAV_4660|M.avium_104 -----------------------MTS-VLIVEDEESLADPLAFLLRKEGF
MMAR_0816|M.marinum_M -----------------------MTS-VLIVEDEESLADPLAFLLRKEGF
MUL_4560|M.ulcerans_Agy99 -----------------------MTS-VLIVEDEESLADPLAFLLRKEGF
Mflv_0082|M.gilvum_PYR-GCK -----------------------MTS-VLIVEDEESLADPLAFLLRKEGF
Mvan_0831|M.vanbaalenii_PYR-1 -----------------------MTS-VLIVEDEESLADPLAFLLRKEGF
TH_4312|M.thermoresistible__bu -----------------------MTS-VLIVEDEESLADPLAFLLRKEGF
MLBr_00773|M.leprae_Br4923 --------------------MDIMRQRILVVDDDASLAEMLTIVLRGEGF
MSMEG_1874|M.smegmatis_MC2_155 --------------------MDTMRQRILVVDDDPSLAEMLTIVLRGEGF
MAB_4848c|M.abscessus_ATCC_199 MSIEARHTEGAAKLSEHRAGAAPSRGAIMLVDTDPQIAAGLSEQAAQIGI
:::*: : .:* *: *:
Mb0501|M.bovis_AF2122/97 EATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVI
Rv0491|M.tuberculosis_H37Rv EATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVI
MAV_4660|M.avium_104 EATVVTDGSAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVI
MMAR_0816|M.marinum_M EATVVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVI
MUL_4560|M.ulcerans_Agy99 EATVVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVI
Mflv_0082|M.gilvum_PYR-GCK ETTVVTDGPSALAEFERAGADIVLLDLMLPGMSGTDVCKQLRSRSSVPVI
Mvan_0831|M.vanbaalenii_PYR-1 EATVVADGPSALAEFERAGADIVLLDLMLPGMSGTDVCKQLRSRSSVPVI
TH_4312|M.thermoresistible__bu ETTIVTDGPSALAEFERSGADIILLDLMLPGMSGTDVCRRLRAKSKVPVI
MLBr_00773|M.leprae_Br4923 DTAVIGDGTQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIV
MSMEG_1874|M.smegmatis_MC2_155 DTAVIGDGSQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIV
MAB_4848c|M.abscessus_ATCC_199 STLWCRDGADALLHIGAEPPDVLVLAAHTDIINAAQITAAVRGRWQLPIL
.: **. ** . .*:::* :.. :: :*. :*::
Mb0501|M.bovis_AF2122/97 MVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSE
Rv0491|M.tuberculosis_H37Rv MVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSE
MAV_4660|M.avium_104 MVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSE
MMAR_0816|M.marinum_M MVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSE
MUL_4560|M.ulcerans_Agy99 MVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSE
Mflv_0082|M.gilvum_PYR-GCK MVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGADADDLG
Mvan_0831|M.vanbaalenii_PYR-1 MVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGSDADDAG
TH_4312|M.thermoresistible__bu MVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGSDLDGAD
MLBr_00773|M.leprae_Br4923 MLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRNDD-----
MSMEG_1874|M.smegmatis_MC2_155 MLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARLRRNED-----
MAB_4848c|M.abscessus_ATCC_199 IGAAPATDLIARKALAAGASAVITRPYDINAISPFVLGSEEQPGS-----
: :* : .* **. : :*:. . : . : . .: .
Mb0501|M.bovis_AF2122/97 MSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTR
Rv0491|M.tuberculosis_H37Rv MSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTR
MAV_4660|M.avium_104 ISDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTR
MMAR_0816|M.marinum_M VSDGVLESGPVRMDVERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTR
MUL_4560|M.ulcerans_Agy99 VSDGVLESGPVRMDVERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTR
Mflv_0082|M.gilvum_PYR-GCK VADGVLEAGPVRMDVERHVVSVNGAPITLPLKEFDLLEYLMRNSGRVLTR
Mvan_0831|M.vanbaalenii_PYR-1 IGDGVLEAGPVRMDVERHVVSVNGQSITLPLKEFDLLEYLMRNSGRVLTR
TH_4312|M.thermoresistible__bu VDDSVLEAGPVRMDVDRHVVTVRGEPITLPLKEFELLEYLLRNSGRVLTR
MLBr_00773|M.leprae_Br4923 EPAEMLSIADVDIDVPAHKVTRNGEHISLTPLEFDLLVALARKPRQVFTR
MSMEG_1874|M.smegmatis_MC2_155 EPAEMLSIGDVEIDVPAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTR
MAB_4848c|M.abscessus_ATCC_199 -GPAVYIAGPIQVDRRGHETRVRDRDVQLTVRELELLVFLIEQHGRVASS
: . : :* * . .. : *. *::** * .: :* :
Mb0501|M.bovis_AF2122/97 GQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKL
Rv0491|M.tuberculosis_H37Rv GQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKL
MAV_4660|M.avium_104 GQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKL
MMAR_0816|M.marinum_M GQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKL
MUL_4560|M.ulcerans_Agy99 GQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKL
Mflv_0082|M.gilvum_PYR-GCK GQLIDRVWGADYVGDTKTLDVHVKRLRSKIESDPANPVHLVTVRGLGYKL
Mvan_0831|M.vanbaalenii_PYR-1 GQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKL
TH_4312|M.thermoresistible__bu GQLIDRVWGADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKL
MLBr_00773|M.leprae_Br4923 DVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKA
MSMEG_1874|M.smegmatis_MC2_155 DVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKA
MAB_4848c|M.abscessus_ATCC_199 EEISRAVWGR--PSDTNTVAVHVRRLREKLGDDPEHGEYIRTIRGAGYRL
: *** .**. : ***:*** *: ** : : *:** **:
Mb0501|M.bovis_AF2122/97 EG----
Rv0491|M.tuberculosis_H37Rv EG----
MAV_4660|M.avium_104 EG----
MMAR_0816|M.marinum_M EG----
MUL_4560|M.ulcerans_Agy99 EG----
Mflv_0082|M.gilvum_PYR-GCK EG----
Mvan_0831|M.vanbaalenii_PYR-1 EG----
TH_4312|M.thermoresistible__bu EG----
MLBr_00773|M.leprae_Br4923 GPP---
MSMEG_1874|M.smegmatis_MC2_155 GPP---
MAB_4848c|M.abscessus_ATCC_199 APSISS