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GKSPYAVLGGAALAGVGAAVAGIAGSAAALRSPAVLRRLNKWAAHRLTDEQRADRHAAILPTPIPGPSFY SDPGDLAGRVNGEVIRQQYVRPRLPVPGASVQRFMVRSTNTAGDAVPVTATLIEPKRPWRGPGARPVVVR NQPINSLGLKAAPSYRIARGMYVDVPPLAPLLLARNYAVLIPDHEGPRMAYSAGVMAAHAVLDAVRGMHG MRADLVDAPMVMDGYSGGAIATVWAAQEQPTYAPELRFSGAVAGGTPTDYALLYRSMNGALGSGLFAAAT IGQAREYPSMVELFGDFAFYMSTLVKDLPQPALAAAGVARIDLDVLAAVPAPFDSDIAQDVIAANKPGAA APNMPILLYHGSRDRFLGDQFIPEQGVTELVGSWRSKGAMVDYLPVPGEHMIAAGWAMPRVLRWMRDVLG D*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4707c | - | - | 100% (422) | putative lipase |
| M. abscessus ATCC 19977 | MAB_3282c | - | e-150 | 63.95% (405) | lipase |
| M. abscessus ATCC 19977 | MAB_2676 | - | 1e-22 | 26.79% (418) | hypothetical protein MAB_2676 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1618c | - | 6e-26 | 27.51% (378) | hypothetical protein Mb1618c |
| M. gilvum PYR-GCK | Mflv_3621 | - | 3e-29 | 28.61% (388) | triacylglycerol lipase |
| M. tuberculosis H37Rv | Rv1592c | - | 6e-26 | 27.51% (378) | hypothetical protein Rv1592c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2389 | - | 8e-25 | 28.19% (376) | hypothetical protein MMAR_2389 |
| M. avium 104 | MAV_3194 | - | 4e-23 | 27.20% (397) | secretory lipase family protein |
| M. smegmatis MC2 155 | MSMEG_3197 | - | 8e-28 | 30.40% (375) | lipase |
| M. thermoresistible (build 8) | TH_2810 | - | 4e-29 | 29.58% (382) | PUTATIVE Triacylglycerol lipase |
| M. ulcerans Agy99 | MUL_1566 | - | 3e-24 | 27.66% (376) | hypothetical protein MUL_1566 |
| M. vanbaalenii PYR-1 | Mvan_2796 | - | 5e-31 | 29.08% (368) | triacylglycerol lipase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1618c|M.bovis_AF2122/97 ---------MVEPGNLAGATGAEWIG------------------------
Rv1592c|M.tuberculosis_H37Rv ---------MVEPGNLAGATGAEWIG------------------------
MMAR_2389|M.marinum_M MPKAMKGALMVKLGSLADARAAEWIG------------------------
MUL_1566|M.ulcerans_Agy99 ---------MVKLGSLADARAAGWIG------------------------
MAV_3194|M.avium_104 ---------MAELGNLAGTHGAEWIA------------------------
MSMEG_3197|M.smegmatis_MC2_155 ----------MDLSSAAKAADAEWIG------------------------
Mflv_3621|M.gilvum_PYR-GCK ----------MDLGNVARSTGAEWIG------------------------
Mvan_2796|M.vanbaalenii_PYR-1 ----------MDLGNVARSTGAEWIG------------------------
TH_2810|M.thermoresistible__bu ----------MDLGSAAQSTGAEWIG------------------------
MAB_4707c|M.abscessus_ATCC_199 ----MGKSPYAVLGGAALAGVGAAVAGIAGSAAALRSPAVLRRLNKWAAH
.. * : . :.
Mb1618c|M.bovis_AF2122/97 RPPHEELQRKVRPLLPSDDP---FYFPPAGYQHAVPGTVLRSRDVELAFM
Rv1592c|M.tuberculosis_H37Rv RPPHEELQRKVRPLLPSDDP---FYFPPAGYQHAVPGTVLRSRDVELAFM
MMAR_2389|M.marinum_M RPPHEELQRKVRPLLPSDDP---FYDPPAGYHHAEPGTVLRSREVELAFL
MUL_1566|M.ulcerans_Agy99 RPPHEELQRKVRPLLPSDDP---FYDPPAGYHHAEPGTVLRSREVELAFL
MAV_3194|M.avium_104 RPPHEELQRKVRPLLPSDDP---FYQPPLGFQHAEPGTVLRSRDVELAFL
MSMEG_3197|M.smegmatis_MC2_155 RAPHEELDRDARPGLPGEDP---FYLPPAGYHHAEPGTVLRSRDVELAFL
Mflv_3621|M.gilvum_PYR-GCK QPRHEELRPRTRPVIPADDP---FYEPPEGYEHARPGTVLRSRDVELAFL
Mvan_2796|M.vanbaalenii_PYR-1 QPFHEPLRPRSRPMIPAKDD---FYEPPAGFEHARPGTVLRSRDVELAFL
TH_2810|M.thermoresistible__bu RPTHEALR-RTRPILPERDP---FYEPPPGFEHARPGTVLRSRDVELAFM
MAB_4707c|M.abscessus_ATCC_199 RLTDEQRADRHAAILPTPIPGPSFYSDPGDLAGRVNGEVIRQQYVRPRLP
: .* . :* ** * . * *:*.: *. :
Mb1618c|M.bovis_AF2122/97 GLIPQPVTATQLLYRTTNMYGNPEATVTTVIVPAE-LAPGQTCPLLSYQC
Rv1592c|M.tuberculosis_H37Rv GLIPQPVTATQLLYRTTNMYGNPEATVTTVIVPAE-LAPGQTCPLLSYQC
MMAR_2389|M.marinum_M GLIPQSITATQLLYRTTDMYGNPEATVTTVILPAE-VAPGQTYPLLSYQC
MUL_1566|M.ulcerans_Agy99 GLIPQSITATQLLYRTTDMYGNPEATVTTVILPAE-VAPGQTYPLLSYQC
MAV_3194|M.avium_104 GLIPQPIKAVQLLYRTMDMNGEPEATVTTVIVPAD-AVPGRPCPLLSYQC
MSMEG_3197|M.smegmatis_MC2_155 GLVPQALHATQLLYRTTDRNGAPEAAVTTVIMPPD-ARAG--CPIVSYQC
Mflv_3621|M.gilvum_PYR-GCK GLIPQKFSATQLLYRTTDLYGQPQATVTTVLAPTE-RTDRRPLPIVSYQC
Mvan_2796|M.vanbaalenii_PYR-1 GVIPQKFTATQLLYRTTDLNGEAQATVTTVVVPSE-RTSDGPLPIVSYQC
TH_2810|M.thermoresistible__bu GLIPQKFTATQLLYRTTGFDGRPRATVTTVVVPAE-RDKNGRCPVVSYQC
MAB_4707c|M.abscessus_ATCC_199 ---VPGASVQRFMVRSTNTAGDAVPVTATLIEPKRPWRGPGARPVVVRNQ
. ::: *: . * . ...:*:: * *:: :
Mb1618c|M.bovis_AF2122/97 AIDAMSSRCFPSYALRRRAKALGSLTQMELLMISAALAEGWAVSVPDHEG
Rv1592c|M.tuberculosis_H37Rv AIDAMSSRCFPSYALRRRAKALGSLTQMELLMISAALAEGWAVSVPDHEG
MMAR_2389|M.marinum_M AIDAMSSRCFPSYALRRGAKAIGSLTQLELLLITAAVAEGWAVSVPDHEG
MUL_1566|M.ulcerans_Agy99 AIDAMSSRCFPSYALRRGAKAIGSLTQLELLLITAAVAEGWAVSVPDHEG
MAV_3194|M.avium_104 AIDAVSSRCFPSYALRRRAKALGSIGQFELFLITAAVAEGWAVSVPDHEG
MSMEG_3197|M.smegmatis_MC2_155 AIDAISATCFPSYALRRHAKVTGGLAQFELLLITAALAEGWAVSVPDHEG
Mflv_3621|M.gilvum_PYR-GCK AIDAVAGRCFPSYALRRGAKALGAVAQFEFLLIAAALAEGWAVSVPDHEG
Mvan_2796|M.vanbaalenii_PYR-1 AIDAVAGRCFPSYALRRGAKALGSFAQFEFLLVAAALAEGWAVSVPDHEG
TH_2810|M.thermoresistible__bu AIDAVTSRCFPSYALRRGARAVGALAQFEFLLIAAALAEGWAVSVPDHEG
MAB_4707c|M.abscessus_ATCC_199 PINSLGLKAAPSYRIARGMYVD------VPPLAPLLLARNYAVLIPDHEG
.*::: . *** : * . : . :*..:** :*****
Mb1618c|M.bovis_AF2122/97 PKGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAW
Rv1592c|M.tuberculosis_H37Rv PKGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAW
MMAR_2389|M.marinum_M VRGLWGTPYEPGYRVLDGIRAALSAERLALPQSAPIGLWGYSGGGLASAW
MUL_1566|M.ulcerans_Agy99 VRGLWGTPYEPGYRVLDGIRAALSAERLALPQSAPIGLWGYSGGGLASAW
MAV_3194|M.avium_104 LRGLWGAPYEPGYRVLDGIRAALGSERLGLSPSAPIGLWGYSGGGLASAW
MSMEG_3197|M.smegmatis_MC2_155 LDGMWGAPYEPGYHVLDGLRAALNSERLPLTDASPIGLWGYSGGGLASGW
Mflv_3621|M.gilvum_PYR-GCK TTGMWGAPFEPGYHVLDGIRAAVNHRPLGLAEDAPVGLWGYSGGGLASAW
Mvan_2796|M.vanbaalenii_PYR-1 TSGMWGAPHEPGYHVLDGVRAALNHGPLGLSPDAPVGLWGYSGGGLASAW
TH_2810|M.thermoresistible__bu PDGSWGAPLEPGYHILDGLRAALGYERLNLAVDAPVGLWGYSGGGLASAW
MAB_4707c|M.abscessus_ATCC_199 PRMAYSAGVMAAHAVLDAVRGMHGMR--ADLVDAPMVMDGYSGGAIATVW
:.: ..: :**.:*. . :*: : *****.:*: *
Mb1618c|M.bovis_AF2122/97 AAEACGEYAPDLDIVGAVLGSPVGDLGHTFRRLNGTLLAGLPALVVAALQ
Rv1592c|M.tuberculosis_H37Rv AAEACGEYAPDLDIVGAVLGSPVGDLGHTFRRLNGTLLAGLPALVVAALQ
MMAR_2389|M.marinum_M AAEMCGEYAPELNIVGAVLGSPVGDLGNTFRRLNGTLLAGLPAMVVAALG
MUL_1566|M.ulcerans_Agy99 AAEMCGEYAPDLNIVGAVLGSPVGDLGNTFRRLNGTLLAGLPAMVVAALG
MAV_3194|M.avium_104 AAETCAEYAPELNVVGAVLGSPVGDLGNTFRRLNGSFLSGLPALVVAALA
MSMEG_3197|M.smegmatis_MC2_155 AAEMSGSYAPELNIVGAVLGSPVGDLGHTFRRLNGTVFSGLPALVVAALA
Mflv_3621|M.gilvum_PYR-GCK AAEVHDSYAPELNVVGAVLGSPVGDLGHAFRRLNGSIYSGLPAMVVAALT
Mvan_2796|M.vanbaalenii_PYR-1 AAEVQDAYAPELNVVGAVLGSPVGDLGHTFRRLNGSIYAGLPALVVAALT
TH_2810|M.thermoresistible__bu AAEVCRDYAPDLNVVGAVLGSPVGDLGSAFRRLNGSLYAGLPAMVVAALA
MAB_4707c|M.abscessus_ATCC_199 AAQEQPTYAPELRFSGAVAGGTPTDYALLYRSMNGALGSGLFAAATIGQA
**: ***:* . *** *.. * . :* :**:. :** * .. .
Mb1618c|M.bovis_AF2122/97 HSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGDFLDEPL
Rv1592c|M.tuberculosis_H37Rv HSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAGRDMGDFLDEPL
MMAR_2389|M.marinum_M HAYPGLDRVIKQHANEDGIELLERLEQMTTAEAVIRMANNDLGHYLDEPL
MUL_1566|M.ulcerans_Agy99 HAYPGLDRVIKQHANEDGIELLERLEQMTTAEAVIRMANNDLGHYLDEPL
MAV_3194|M.avium_104 HIYPDLDRVIKEHANEEGRALLDSLEKMTTVEAVIRMAGKNMGDYLDAPL
MSMEG_3197|M.smegmatis_MC2_155 DIYPGLNRVIAEHATTEGRKLLQRLHKMSTIEAVLRLARKDMDDLVDLPL
Mflv_3621|M.gilvum_PYR-GCK HVYPDLNRIIQQHATVEGKAMLARIEKMTTAHAMLSLVGKDMAHWVDRPL
Mvan_2796|M.vanbaalenii_PYR-1 HIYPDLHRVIQEHATEDGKVMLARIEKMTTAHAMISLVGRDMAHMIDRPL
TH_2810|M.thermoresistible__bu HIFPEVDQIIDEHATETGKAMLQRVEKMTTAHAVLRMIGMDMGKLVDQPL
MAB_4707c|M.abscessus_ATCC_199 REYPSMVELFGDFAFYMS-TLVKDLPQPALAAAGVARIDLDVLAAVPAPF
:* : .:: :.* . :: : : : * : :: : *:
Mb1618c|M.bovis_AF2122/97 EDILSTPEVSHVFGDTKLGSAVPTPPVLIVQAVHD-----YLIDVSDIDA
Rv1592c|M.tuberculosis_H37Rv EDILSTPEISHVFGDTKLGSAVPTPPVLIVQAVHD-----YLIDVSDIDA
MMAR_2389|M.marinum_M DDVLSTPEVVHVFDDIKLGAAVPAPPVLIVQAVHD-----YLISVDDIDT
MUL_1566|M.ulcerans_Agy99 EDVLSTPEVVHVFDDIKLGAAVPAPPVLIVQAVHD-----YLISVDDIDT
MAV_3194|M.avium_104 EQILSTPEVTYVFDHIRLGAAVPTPPVLIVQAVHD-----YLIDVHDIDV
MSMEG_3197|M.smegmatis_MC2_155 EQILDSPEVTEVFDDIKLGVATPNPPVLLIQAVHD-----ELISVSSIDE
Mflv_3621|M.gilvum_PYR-GCK EEILLTPEVQHVFDSIKLGTSAPKVPVLIVQAVHD-----RIISVDDIDE
Mvan_2796|M.vanbaalenii_PYR-1 EEILLSPEVQHVFDSIKLGTAAPKVPLLIVQAVHD-----RIISVDDIDA
TH_2810|M.thermoresistible__bu EEILQTPAMQRVFDRIKLGSAIPAPPVLLVQACHD-----RIVSVDDIDT
MAB_4707c|M.abscessus_ATCC_199 DSDIA----QDVIAANKPGAAAPNMPILLYHGSRDRFLGDQFIPEQGVTE
:. : *: : * : * *:*: :. :* :: .:
Mb1618c|M.bovis_AF2122/97 LADSYTAGGANVTYHRDLFSEHVSLHPLSAPMTLRWLTDRFAGKPLTDHR
Rv1592c|M.tuberculosis_H37Rv LADSYTAGGANVTYHRDLFSEHVSLHPLSAPMTLRWLTDRFAGKPLTDHR
MMAR_2389|M.marinum_M LAESYSTGGARVTYHRDAFNEHMMLHPLSAPMTLRWLTDRFAGLPLTEHV
MUL_1566|M.ulcerans_Agy99 LAESYSTGGARVTYHRDAFNEHMMLHPLSAPMTLRWLTDRFAGLPLTEHV
MAV_3194|M.avium_104 LADAYSAGGAQVTYHRDAFNEHMMLHPLSAPMTLRWLTDRFEGRPVTEHL
MSMEG_3197|M.smegmatis_MC2_155 LAEKYLTGGASVTYHRDLFSEHLLLHPMSAPMALRWLTDRFAARPLTANL
Mflv_3621|M.gilvum_PYR-GCK LTETYTAGGASVTYHRDMFSEHLLLHPMSAPMTLRWLRDRFAGRPISAHI
Mvan_2796|M.vanbaalenii_PYR-1 LTETYTSGGASVTYHRDMLSEHLLLHPMSAPMTLRWLRDRFAGRPLRTHI
TH_2810|M.thermoresistible__bu LADTYIEGGVRVTYHRDMFSEHMLLHPMSAPMTLRWLRDRFAGQPLKHNL
MAB_4707c|M.abscessus_ATCC_199 LVGSWRSKGAMVDYLP-VPGEHMIAAGWAMPRVLRWMRDVLGD-------
*. : *. * * .**: : * .***: * :
Mb1618c|M.bovis_AF2122/97 VRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL------------
Rv1592c|M.tuberculosis_H37Rv VRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRRPL------------
MMAR_2389|M.marinum_M IRTTWPTMFNPMTYAGMARLAVIAAKMITGRKIHRRPL------------
MUL_1566|M.ulcerans_Agy99 IRTTWPTMFNPMTYAGMARLAVTAAKMITGRKIHRRPL------------
MAV_3194|M.avium_104 IRTTWPTMFNPMTYVGMARLLKIAAKVVTGRKIHRRPL------------
MSMEG_3197|M.smegmatis_MC2_155 VRSKWPTLLNPVTYVGMARLAGIAAKVVTGRALRRSPL------------
Mflv_3621|M.gilvum_PYR-GCK ARTKWPTLLNPSTYRGMLTLGKITAKVVLGRRVERQP-------------
Mvan_2796|M.vanbaalenii_PYR-1 SRTKWPTLLNPSTYRGMLTLGKITAKVMLGRRVERQP-------------
TH_2810|M.thermoresistible__bu TRTKWPTMFNPSTYRGMLRLGLITAKVLTGRRVDRRPXXXRLHAEMIAEL
MAB_4707c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1618c|M.bovis_AF2122/97 --------------------------------------------------
Rv1592c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2389|M.marinum_M --------------------------------------------------
MUL_1566|M.ulcerans_Agy99 --------------------------------------------------
MAV_3194|M.avium_104 --------------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK --------------------------------------LSQFDL------
Mvan_2796|M.vanbaalenii_PYR-1 --------------------------------------LSRFDQ------
TH_2810|M.thermoresistible__bu RWPGDPDPDSGIDIWAMELDPGQLAVLDILRRPDVMTALTEWDAGDALGD
MAB_4707c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1618c|M.bovis_AF2122/97 --------------------------------------------------
Rv1592c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2389|M.marinum_M --------------------------------------------------
MUL_1566|M.ulcerans_Agy99 --------------------------------------------------
MAV_3194|M.avium_104 --------------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2810|M.thermoresistible__bu YTRERIRSSSALAVVTVEGREPADYLRGGSALEAVWIRAQQRGLAVHPVS
MAB_4707c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1618c|M.bovis_AF2122/97 --------------------------------------------------
Rv1592c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2389|M.marinum_M --------------------------------------------------
MUL_1566|M.ulcerans_Agy99 --------------------------------------------------
MAV_3194|M.avium_104 --------------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2810|M.thermoresistible__bu PLFLYAHEEDELRALSPRFASSLVNLRREFHDLAGTRRGESQIIVFRLFE
MAB_4707c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1618c|M.bovis_AF2122/97 ------------------
Rv1592c|M.tuberculosis_H37Rv ------------------
MMAR_2389|M.marinum_M ------------------
MUL_1566|M.ulcerans_Agy99 ------------------
MAV_3194|M.avium_104 ------------------
MSMEG_3197|M.smegmatis_MC2_155 ------------------
Mflv_3621|M.gilvum_PYR-GCK ------------------
Mvan_2796|M.vanbaalenii_PYR-1 ------------------
TH_2810|M.thermoresistible__bu APPASVRSRRRSGGIGVD
MAB_4707c|M.abscessus_ATCC_199 ------------------