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LRCPRTGLRCRSGKGGAMSDVNQPRHGNRVLVTGLGVVCGLGMNWQSMWDGLVNGRSAIQAWSPPDVPNF PVGYAAPVDDQAFTALFPDFGAPMEKRTRFGLAAAQQALEDGGVTNAAALARVGVSIASEMPERESGELL SAYVDGVVDWKRVHEQQIGLDRSHAPLATGDALATEIATRSGLAGPTLNLNTACAGATHALGHGFRMIRR GETDAVIAGGAVSPLNLPIMTSLYLLGAPSTSKLYGDRLCRAFDRDRSGMVTAEGAAMVLLESESSALAR GAHVYGEVAGFGSSLDAYQVTAPHPQGGGSVLAMQRALADAGVAPSEVGYVSAHGTSTPLSDAAETAAIK EVFRTGEHYRSLMVSSIKTMLGHMLAAAGAQQLISTVLSLRDGIIPPTLNLENPDPACDLDYVPGQARKA DIEVAINNSLGFGGLNAALVVRRYDN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2030 | - | - | 100% (446) | 3-oxoacyl-(Acyl-carrier-protein) synthase II KasA |
| M. abscessus ATCC 19977 | MAB_1877c | - | 2e-56 | 33.64% (428) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. abscessus ATCC 19977 | MAB_2028 | - | 1e-54 | 33.26% (436) | 3-oxoacyl-(Acyl-carrier-protein) synthase II KasB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2269 | kasA | 1e-52 | 32.28% (443) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. gilvum PYR-GCK | Mflv_1799 | - | 2e-54 | 34.53% (417) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. tuberculosis H37Rv | Rv2245 | kasA | 1e-52 | 32.28% (443) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. leprae Br4923 | MLBr_01655 | kasA | 5e-49 | 37.24% (290) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. marinum M | MMAR_3338 | kasA | 1e-51 | 38.35% (279) | 3-oxoacyl- |
| M. avium 104 | MAV_2192 | - | 6e-52 | 39.07% (279) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. smegmatis MC2 155 | MSMEG_4328 | - | 4e-51 | 33.25% (418) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. thermoresistible (build 8) | TH_2837 | - | 7e-52 | 33.18% (425) | PUTATIVE beta-ketoacyl synthase |
| M. ulcerans Agy99 | MUL_1304 | kasA | 1e-52 | 38.35% (279) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. vanbaalenii PYR-1 | Mvan_4950 | - | 2e-52 | 34.05% (420) | 3-oxoacyl-(acyl carrier protein) synthase II |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3338|M.marinum_M ----------------MTKPSTANGGYPSVVVTAVTATTSISPDIESTWK
MUL_1304|M.ulcerans_Agy99 ----------------MTKPSTANGGYPSVVVTAVTATTSISPDIESTWK
MAV_2192|M.avium_104 ----------------MSKPSTANGGYPSVVVTAVTATTSIAPDVESTWK
Mb2269|M.bovis_AF2122/97 ----------------MSQPSTANGGFPSVVVTAVTATTSISPDIESTWK
Rv2245|M.tuberculosis_H37Rv ----------------MSQPSTANGGFPSVVVTAVTATTSISPDIESTWK
MLBr_01655|M.leprae_Br4923 ----------------MTMPSTANGGFPSVVVTAVTATTSISPDIESTWK
Mflv_1799|M.gilvum_PYR-GCK -----------------------MGKFPDVVVTGVAMTTALGTDAESTWQ
Mvan_4950|M.vanbaalenii_PYR-1 -----------------------MSRFPDVVVTGVAMTTALGTDVESTWQ
MSMEG_4328|M.smegmatis_MC2_155 -----------------MAALSTGNGLPNVVVTGVAMTTALATDAESTWK
TH_2837|M.thermoresistible__bu -----------------------------VVVTGVAMTTALATDAEGTWK
MAB_2030|M.abscessus_ATCC_1997 MRCPRTGLRCRSGKGGAMSDVNQPRHGNRVLVTGLGVVCGLGMNWQSMWD
*:**.: . .:. : :. *.
MMAR_3338|M.marinum_M GLLAGESGIHVLDDEYLTKWDLPVKIGGHLKDPVDNHMGRLDMRRMSYVQ
MUL_1304|M.ulcerans_Agy99 GLLAGESGIHVLDDEYLTKWDLPVKIGGHLKDPVDNHMGRLDIRRMSYVQ
MAV_2192|M.avium_104 GLLAGESGIHVLEDDYITKWDLPVRIGGHLKEPIDERMSRLDLRRMSYVQ
Mb2269|M.bovis_AF2122/97 GLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQ
Rv2245|M.tuberculosis_H37Rv GLLAGESGIHALEDEFVTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQ
MLBr_01655|M.leprae_Br4923 GLLAGESGIHVLEDEYITKWDLPVKIGGHLKEPVDSHMSRLDLRRMSYVQ
Mflv_1799|M.gilvum_PYR-GCK ALLEGRSGIRVLQDSFIEEFDLPVRIGGHLLETFDEQLTPEENYNLSYVQ
Mvan_4950|M.vanbaalenii_PYR-1 ALLEGRSGIRRLEDSFIEEFDLPVRIGGHLLETFDEQLTPEENWELSYVQ
MSMEG_4328|M.smegmatis_MC2_155 KLLDGQSGIRTLTDPFVEEYNLPVRIGGHLLEEFDSELTRVELRRLSYLQ
TH_2837|M.thermoresistible__bu KLLDGQSGIRLLEDDFIEKYDLPVRIGGHLLEDFDSELTRVELRRLSYLQ
MAB_2030|M.abscessus_ATCC_1997 GLVNGRSAIQAWSPPDVP--NFPVGYAAPVDDQAFTALFPDFGAPMEKRT
*: *.*.*: : ::.* .. : : : :.
MMAR_3338|M.marinum_M RMAKFLSGQLWESAGSP-EVDPDRFTVVVGTGLG----GAERIVESYDLM
MUL_1304|M.ulcerans_Agy99 RMAKFLSGQLWESAGSP-EVDPDRFTVVVGTGLG----GAERIVESYDLM
MAV_2192|M.avium_104 RLAKLLSTQLWETAGNP-ELDPDRFSVVVGTGLG----GAERIVESYDLM
Mb2269|M.bovis_AF2122/97 RMGKLLGGQLWESAGSP-EVDPDRFAVVVGTGLG----GAERIVESYDLM
Rv2245|M.tuberculosis_H37Rv RMGKLLGGQLWESAGSP-EVDPDRFAVVVGTGLG----GAERIVESYDLM
MLBr_01655|M.leprae_Br4923 RMSKLLSGRLWESTGSP-EVDPDRFTVVVGTGLG----GAERIVESYDLM
Mflv_1799|M.gilvum_PYR-GCK RMAVVLGRRVWEHAGSP-DVDPNRLAVSIGTGMG----GIEELLFAYENL
Mvan_4950|M.vanbaalenii_PYR-1 RMAVVLGRRVWENAGSP-DVDPNRLTVSIGTGMG----GIEELAFAYDHL
MSMEG_4328|M.smegmatis_MC2_155 KMATVLGRRVWANAGSP-EVDARRLMVSMGTGLG----STEELVFAYDGM
TH_2837|M.thermoresistible__bu KMSTVLSRRVWENAGSP-EVDPRRLMVSIGTGMG----STEELVFSYDDM
MAB_2030|M.abscessus_ATCC_1997 RFGLAAAQQALEDGGVTNAAALARVGVSIASEMPERESGELLSAYVDGVV
::. . : * . *. * :.: : . :
MMAR_3338|M.marinum_M NEGGPRKVSPLAVQMIMPNGAAAVVGLQLGARAGVITPVS----ACSSGS
MUL_1304|M.ulcerans_Agy99 NEGGPRKVSPLTVQMIMPNGAAAVVGLQLGARAGVITPVS----ACSSGS
MAV_2192|M.avium_104 NEGGPRKVSPLAVQMIMPNGAAAVVGLQLGARAGVITPVS----ACSSGS
Mb2269|M.bovis_AF2122/97 NAGGPRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVS----ACSSGS
Rv2245|M.tuberculosis_H37Rv NAGGPRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVS----ACSSGS
MLBr_01655|M.leprae_Br4923 NAGGPRKVSPLAVQMIMPNGAAATVGLQLGACAGVMTPVS----ACSSGS
Mflv_1799|M.gilvum_PYR-GCK RGARFDEVNPTAVQQYAPSGPSSAVALERHARAGVLAPVS----ACASGS
Mvan_4950|M.vanbaalenii_PYR-1 REHHLELVNPTVVQQYAPSGPSSAVALERHARAGILAPVS----ACASGS
MSMEG_4328|M.smegmatis_MC2_155 RSKGLRAVSPLVVQMYMPNGAAAAIGLERQAKAGVCTSIS----ACASGS
TH_2837|M.thermoresistible__bu RAKGLKAVSPLAVQKYMPNAAAAAVGLERKARAGVITPVS----ACASGS
MAB_2030|M.abscessus_ATCC_1997 DWKRVHEQQIGLDRSHAPLATGDALATEIATRSGLAGPTLNLNTACAGAT
. : * ... .:. : : :*: . **:..:
MMAR_3338|M.marinum_M EAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMR-AMSTRNDEPE
MUL_1304|M.ulcerans_Agy99 EAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMR-AMSTRNDEPE
MAV_2192|M.avium_104 EAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMR-AMSTRNDEPE
Mb2269|M.bovis_AF2122/97 EAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMR-AMSTRNDEPE
Rv2245|M.tuberculosis_H37Rv EAIAHAWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMR-AMSTRNDEPE
MLBr_01655|M.leprae_Br4923 EAIAHAWRQIIMGDADVAVCGGVEGPIEALPIAAFSMMR-AMSTRNDDPE
Mflv_1799|M.gilvum_PYR-GCK EGVAQAWRQIIFGEADIAICGGVEARIEAVPIAGFAQMRIVMSTNNDDPE
Mvan_4950|M.vanbaalenii_PYR-1 EGIAQAWRHIIFGEADIAICGGVEARIEAVPIAGFAQMRIVMSTNNDDPP
MSMEG_4328|M.smegmatis_MC2_155 EAIANAWRNIVLGEADIAICGGVETKIEAVPIAGFAQMRIVLSNSNDDPE
TH_2837|M.thermoresistible__bu EGIAHAWRNIVLGEADIAICGGVETKIEAVPIAGFAQMRIVLSTTNDDPP
MAB_2030|M.abscessus_ATCC_1997 HALGHGFRMIRRGETDAVIAGGAVSPLNLPIMTSLYLLG-APSTSKLYGD
..:.:.:* * *::* .:.**. :: ::.: : . *. :
MMAR_3338|M.marinum_M RASRPFDKDRDGFVFGEAGALLLIETEEHAKARGAKPLARLMGAGITSDA
MUL_1304|M.ulcerans_Agy99 RASRPFDKDRDGFVFGEAGALLLIETEEHAKARGAKPLARLMGAGITSDA
MAV_2192|M.avium_104 RASRPFDKDRDGFVFGEAGALMLIETEEHAKARGAKPLARLMGAGITSDA
Mb2269|M.bovis_AF2122/97 RASRPFDKDRDGFVFGEAGALMLIETEEHAKARGAKPLARLLGAGITSDA
Rv2245|M.tuberculosis_H37Rv RASRPFDKDRDGFVFGEAGALMLIETEEHAKARGAKPLARLLGAGITSDA
MLBr_01655|M.leprae_Br4923 GASRPFDKNRDGFVFGEAGALMLIETEEHAKARGAKPLARLLGAGITSDA
Mflv_1799|M.gilvum_PYR-GCK GACRPFDRDRDGFVFGEGGALLVIETEAHAKARGAKILGRLMGASITSDG
Mvan_4950|M.vanbaalenii_PYR-1 GACRPFDRDRDGFVFGEGGALLVIETAEHARARGAKVLGRLMGASITSDG
MSMEG_4328|M.smegmatis_MC2_155 GACKPFDKDRNGFVFGEAGALMVIETEEHAKARGANILGRLMGASVTSDG
TH_2837|M.thermoresistible__bu GACKPFDKDRNGFVFGEAGALMVIETEEHAKARGANILGRLMGASITSDG
MAB_2030|M.abscessus_ATCC_1997 RLCRAFDRDRSGMVTAEGAAMVLLESESSALARGAHVYGEVAGFGSSLDA
.:.**::*.*:* .*..*::::*: * ****: ..: * . : *.
MMAR_3338|M.marinum_M FHMVAPAADGVRAGRAMQRSMELAGLSPKDIDHVNAHGTATPIGDSAEAN
MUL_1304|M.ulcerans_Agy99 FHMVAPAADGVRAGRAMQRSMELAGLSPTDIDHVNAHGTATPIGDSAEAN
MAV_2192|M.avium_104 FHMVAPAADGVRAGRAMTRSLELAGLSPKDVDHVNAHGTATPIGDTAEAN
Mb2269|M.bovis_AF2122/97 FHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDAAEAN
Rv2245|M.tuberculosis_H37Rv FHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDAAEAN
MLBr_01655|M.leprae_Br4923 FHMVAPAADGVRAGRAMTRSLELAGLSAKDVDHVNAHGTATPIGDSAEAN
Mflv_1799|M.gilvum_PYR-GCK FHMVAPDPNGERAGYAMSHAVELAGLASADIDHVNAHATGTTVGDVAEGI
Mvan_4950|M.vanbaalenii_PYR-1 FHMVAPDPNGKRAGYAMSHAVELAGLSATDIDHVNAHATGTTVGDVAEGV
MSMEG_4328|M.smegmatis_MC2_155 YHIVAPDPNGEQAGYAMTRAIELAGLKPTDIDHVNAHATGTNVGDVAESK
TH_2837|M.thermoresistible__bu YHIVAPDPNGEQAGWAMTRAIELAGLQPSDIDHVNAHATGTTVGDVAEGK
MAB_2030|M.abscessus_ATCC_1997 YQVTAPHPQGGGSVLAMQRALADAGVAPSEVGYVSAHGTSTPLSDAAETA
:::.** .:* : ** ::: **: . ::.:*.**.*.* :.* **
MMAR_3338|M.marinum_M AIR-VAGCEN----AAIYAPKSALGHSIGAVGALESALTVLSLRDGVIPP
MUL_1304|M.ulcerans_Agy99 AIR-VAGFEN----AAIYAPKSALGHSIGAVGALESALTVLSLRDGVIPP
MAV_2192|M.avium_104 AIR-VAGCQE----AAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPP
Mb2269|M.bovis_AF2122/97 AIR-VAGCDQ----AAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPP
Rv2245|M.tuberculosis_H37Rv AIR-VAGCDQ----AAVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPP
MLBr_01655|M.leprae_Br4923 AIR-VAGCEQ----AAVYAPKSALGHSIGAVGALESVLTVLALRDGVIPP
Mflv_1799|M.gilvum_PYR-GCK AINKALGGHK----PAVYAPKGALGHSVGAVGAVESILTLFALRDGVIPP
Mvan_4950|M.vanbaalenii_PYR-1 AINYALGGHK----PAVYAPKGALGHSVGAVGAVESILTLLALRDGVIPA
MSMEG_4328|M.smegmatis_MC2_155 AINNAMGGHK----PAVYAPKGALGHSVGAVGAVESILTVLALRDGIIPP
TH_2837|M.thermoresistible__bu AINNAMKGHR----PAVYAPKAALGHSVGAVGAVESILTVFALRDGVIPP
MAB_2030|M.abscessus_ATCC_1997 AIKEVFRTGEHYRSLMVSSIKTMLGHMLAAAGAQQLISTVLSLRDGIIPP
**. . . : : * *** :.*.** : *:::****:**.
MMAR_3338|M.marinum_M TLNYETPDPEIDLDVVAGEPRYGEFQYAINNSFGFGGHNVALAFGRY--
MUL_1304|M.ulcerans_Agy99 TLNYETPDPEIDLDVVAGEPRYGEFQYAINNSFGFGGHNVALAFGRY--
MAV_2192|M.avium_104 TLNYETPDPEIDLDIVAGEPRYGDYQYAINNSFGFGGHNVALAFGRY--
Mb2269|M.bovis_AF2122/97 TLNYETPDPEIDLDVVAGEPRYGDYRYAVNNSFGFGGHNVALAFGRY--
Rv2245|M.tuberculosis_H37Rv TLNYETPDPEIDLDVVAGEPRYGDYRYAVNNSFGFGGHNVALAFGRY--
MLBr_01655|M.leprae_Br4923 TLNYQTPDPEIDLDIVAGEPRYGDYRYAINNSFGFGGHNVALAFGRY--
Mflv_1799|M.gilvum_PYR-GCK TRNLRNLDPEIDLDVVAGEPRRGRYEYAINNSFGFGGHNVSLVFGRA--
Mvan_4950|M.vanbaalenii_PYR-1 TRNLKNLDPEIDLDVVAGEPRHGDFKYAINNSFGFGGHNVSLVFGRP--
MSMEG_4328|M.smegmatis_MC2_155 TRNLNNLDPEIDLDVVAGEPRQGDYKYAINNSFGFGGHNVALAFGKY--
TH_2837|M.thermoresistible__bu TLNLKNQDPEIDLDVVAGEPRTGDFKYAINNSFGFGGHNVALAFGKY--
MAB_2030|M.abscessus_ATCC_1997 TLNLENPDPACDLDYVPGQARKADIEVAINNSLGFGGLNAALVVRRYDN
* * .. ** *** *.*:.* . . *:***:**** *.:*.. :