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VTRPSTANGGFPNVVVTAIEATTALAADIESTWKGLLAGESGIRILEDDFVDKWDLPVRIGGHLVDDIDS HMTRIDKRRMSYVQRMSKLLARRLWDNAGTPEVDPDRFSVVIGTGLGGGEKIVETYDAMNEGGPRKVSPL AVQMIMPNGAAAVAGLELGARAGVITPVSACSSGSEAIAHAWRQIVMGDADFAVCGGVEGGIEALPIAAF SMMRAMSTRNDDPAGASRPFDKDRDGFVFGEAGVMMIIETEEHAKARGATPLARLMGAGITSDAFHMVAP AADGVRAGHAMKRAMETAGLSPKDISHVNAHATATPIGDTAEANAIRVAGVEHAAVYAPKSALGHSIGAV GALESALTVLALRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYQYAINNSFGFGGHNVALAFGRY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3756 | - | - | 100% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. vanbaalenii PYR-1 | Mvan_3757 | - | e-164 | 68.19% (415) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. vanbaalenii PYR-1 | Mvan_4950 | - | e-147 | 62.90% (407) | 3-oxoacyl-(acyl carrier protein) synthase II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2269 | kasA | 0.0 | 84.62% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. gilvum PYR-GCK | Mflv_2777 | - | 0.0 | 88.70% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. tuberculosis H37Rv | Rv2245 | kasA | 0.0 | 84.62% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. leprae Br4923 | MLBr_01655 | kasA | 0.0 | 84.13% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. abscessus ATCC 19977 | MAB_1877c | - | 0.0 | 80.34% (417) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. marinum M | MMAR_3338 | kasA | 0.0 | 84.86% (416) | 3-oxoacyl- |
| M. avium 104 | MAV_2192 | - | 0.0 | 85.10% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. smegmatis MC2 155 | MSMEG_4327 | - | 0.0 | 92.07% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. thermoresistible (build 8) | TH_3425 | - | 0.0 | 89.30% (402) | PUTATIVE beta-ketoacyl synthase |
| M. ulcerans Agy99 | MUL_1304 | kasA | 0.0 | 84.38% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3756|M.vanbaalenii_PYR-1 MTRPSTANGGFPNVVVTAIEATTALAADIESTWKGLLAGESGIRILEDDF
MSMEG_4327|M.smegmatis_MC2_155 MTRPSTANGGYPNVVVTAVTATTSIAPDIESTWKGLLAGESGIRVLEDEF
Mflv_2777|M.gilvum_PYR-GCK MTRPSTANGGFPNVVVTAVTATTSIAPDIESTWKGLLAGESGIRILEDEF
TH_3425|M.thermoresistible__bu --------------VVTAVTATTSIAPDVEGTWKGLLAGESGIHVLEDDF
Mb2269|M.bovis_AF2122/97 MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEF
Rv2245|M.tuberculosis_H37Rv MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEF
MLBr_01655|M.leprae_Br4923 MTMPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHVLEDEY
MMAR_3338|M.marinum_M MTKPSTANGGYPSVVVTAVTATTSISPDIESTWKGLLAGESGIHVLDDEY
MUL_1304|M.ulcerans_Agy99 MTKPSTANGGYPSVVVTAVTATTSISPDIESTWKGLLAGESGIHVLDDEY
MAV_2192|M.avium_104 MSKPSTANGGYPSVVVTAVTATTSIAPDVESTWKGLLAGESGIHVLEDDY
MAB_1877c|M.abscessus_ATCC_199 MTLPSTANGGFPNVVVTALAATTSIAPDIEGTWKGLIAGESGIEVLEDEF
****: ***:::.*:*.*****:******. *:*::
Mvan_3756|M.vanbaalenii_PYR-1 VDKWDLPVRIGGHLVDDIDSHMTRIDKRRMSYVQRMSKLLARRLWDNAGT
MSMEG_4327|M.smegmatis_MC2_155 VTKWDLPVRIGGHLVDNIDDHMTRLDMRRMSYVQRMSKFLSKQLWENAGA
Mflv_2777|M.gilvum_PYR-GCK VEKWDLAVKIGGHLKEPLDPLMSRLEMRRMSYVQRMSKYLGNQLWDSIGR
TH_3425|M.thermoresistible__bu IEKWDLPVRIGGHLKEAVDDHMTRIDIRRMSYVQRMAKLLSGRVWDAAGN
Mb2269|M.bovis_AF2122/97 VTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGS
Rv2245|M.tuberculosis_H37Rv VTKWDLAVKIGGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGS
MLBr_01655|M.leprae_Br4923 ITKWDLPVKIGGHLKEPVDSHMSRLDLRRMSYVQRMSKLLSGRLWESTGS
MMAR_3338|M.marinum_M LTKWDLPVKIGGHLKDPVDNHMGRLDMRRMSYVQRMAKFLSGQLWESAGS
MUL_1304|M.ulcerans_Agy99 LTKWDLPVKIGGHLKDPVDNHMGRLDIRRMSYVQRMAKFLSGQLWESAGS
MAV_2192|M.avium_104 ITKWDLPVRIGGHLKEPIDERMSRLDLRRMSYVQRLAKLLSTQLWETAGN
MAB_1877c|M.abscessus_ATCC_199 VEKFGLPVWIGGHLKEPIDNHMTRLELRRMAYVQRMALHVGRQVWQNAGS
: *:.*.* ***** : :* * *:: ***:****:. :. ::*: *
Mvan_3756|M.vanbaalenii_PYR-1 PE-VDPDRFSVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPNG
MSMEG_4327|M.smegmatis_MC2_155 PE-VDPDRFAVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPNG
Mflv_2777|M.gilvum_PYR-GCK PE-VDPDRFSVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPNG
TH_3425|M.thermoresistible__bu PE-VDPDRFSVVIGTGLGGGEKIVETYDAMNEGGPRKVSPLAVQMIMPNG
Mb2269|M.bovis_AF2122/97 PE-VDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNG
Rv2245|M.tuberculosis_H37Rv PE-VDPDRFAVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNG
MLBr_01655|M.leprae_Br4923 PE-VDPDRFTVVVGTGLGGAERIVESYDLMNAGGPRKVSPLAVQMIMPNG
MMAR_3338|M.marinum_M PE-VDPDRFTVVVGTGLGGAERIVESYDLMNEGGPRKVSPLAVQMIMPNG
MUL_1304|M.ulcerans_Agy99 PE-VDPDRFTVVVGTGLGGAERIVESYDLMNEGGPRKVSPLTVQMIMPNG
MAV_2192|M.avium_104 PE-LDPDRFSVVVGTGLGGAERIVESYDLMNEGGPRKVSPLAVQMIMPNG
MAB_1877c|M.abscessus_ATCC_199 PDDIDKDRLGVVIGTGLGGGERIVETYDTMNEHGIRKVSPLAVQMCMPNG
*: :* **: **:******.*:***:** ** * ******:*** ****
Mvan_3756|M.vanbaalenii_PYR-1 AAAVAGLELGARAGVITPVSACSSGSEAIAHAWRQIVMGDADFAVCGGVE
MSMEG_4327|M.smegmatis_MC2_155 AAAVVGLELGARAGVITPVSACSSGSEAIAHAWRQIVMGDADFAVCGGVE
Mflv_2777|M.gilvum_PYR-GCK AAAVVGLELGARAGVITPVSACSSGSEGIAHAWRQIVMGDADIAVCGGVE
TH_3425|M.thermoresistible__bu AAAVVGLQLGARAGVITPVSACASGSEAIAHGWRQIVMGDADIAVVGGVE
Mb2269|M.bovis_AF2122/97 AAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
Rv2245|M.tuberculosis_H37Rv AAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
MLBr_01655|M.leprae_Br4923 AAATVGLQLGACAGVMTPVSACSSGSEAIAHAWRQIIMGDADVAVCGGVE
MMAR_3338|M.marinum_M AAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
MUL_1304|M.ulcerans_Agy99 AAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
MAV_2192|M.avium_104 AAAVVGLQLGARAGVITPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE
MAB_1877c|M.abscessus_ATCC_199 AAAVVGLEIGARAGVITPVSACSSGSEAIAHAWRQIVMGDADMIVCGGVE
***. **::** ***:******:****.***.****:*****. * ****
Mvan_3756|M.vanbaalenii_PYR-1 GGIEALPIAAFSMMRAMSTRNDDPAGASRPFDKDRDGFVFGEAGVMMIIE
MSMEG_4327|M.smegmatis_MC2_155 GGIEALPIAAFSMMRAMSTRNDDPQGASRPFDKDRDGFVFGEAGAMMIIE
Mflv_2777|M.gilvum_PYR-GCK GGIEALPIAAFSMMRAMSTRNEDPEGASRPFDKNRDGFVFGEAGALMVIE
TH_3425|M.thermoresistible__bu GGIEALPIAAFSMMRAMSTRNDDPEGASRPFDKDRDGFVFGEAGALMVIE
Mb2269|M.bovis_AF2122/97 GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIE
Rv2245|M.tuberculosis_H37Rv GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIE
MLBr_01655|M.leprae_Br4923 GPIEALPIAAFSMMRAMSTRNDDPEGASRPFDKNRDGFVFGEAGALMLIE
MMAR_3338|M.marinum_M GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALLLIE
MUL_1304|M.ulcerans_Agy99 GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALLLIE
MAV_2192|M.avium_104 GPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIE
MAB_1877c|M.abscessus_ATCC_199 GMIEALPIAAFSMMRAMSTRNDEPEKASRPFDKDRDGFVFGEAGALMVIE
* *******************::* *******:**********.:::**
Mvan_3756|M.vanbaalenii_PYR-1 TEEHAKARGATPLARLMGAGITSDAFHMVAPAADGVRAGHAMKRAMETAG
MSMEG_4327|M.smegmatis_MC2_155 TEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGLRAGQAMKRAMETAG
Mflv_2777|M.gilvum_PYR-GCK TEEHALARGAKPLARLLGAGITSDAFHMVAPASDGQRAGSAMKRAMETAG
TH_3425|M.thermoresistible__bu TEEHAKARGAQPLARLLGAGITSDAFHMVAPASDGVRAGHAMKRAMETAG
Mb2269|M.bovis_AF2122/97 TEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAG
Rv2245|M.tuberculosis_H37Rv TEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAG
MLBr_01655|M.leprae_Br4923 TEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAG
MMAR_3338|M.marinum_M TEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGVRAGRAMQRSMELAG
MUL_1304|M.ulcerans_Agy99 TEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGVRAGRAMQRSMELAG
MAV_2192|M.avium_104 TEEHAKARGAKPLARLMGAGITSDAFHMVAPAADGVRAGRAMTRSLELAG
MAB_1877c|M.abscessus_ATCC_199 TEEHAKARGAQIIGRVMGAGITSDAYHMVAPGPDGIRAGAAMTRAIQTAG
***** **** :.*::********:*****..** *** ** *::: **
Mvan_3756|M.vanbaalenii_PYR-1 LSPKDISHVNAHATATPIGDTAEANAIRVAGVEHAAVYAPKSALGHSIGA
MSMEG_4327|M.smegmatis_MC2_155 LDPKDIDHVNAHATATPIGDTAEANALRVAGVEHAAVYAPKSALGHSIGA
Mflv_2777|M.gilvum_PYR-GCK LSPKDIDHVNAHATSTSIGDVAEANAIRVAGVEHAAVYAPKSALGHSIGA
TH_3425|M.thermoresistible__bu LSPKDIDHVNAHATGTPIGDTAEANAIRVAGVEHAPVYAPKSALGHSIGA
Mb2269|M.bovis_AF2122/97 LSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGA
Rv2245|M.tuberculosis_H37Rv LSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGA
MLBr_01655|M.leprae_Br4923 LSAKDVDHVNAHGTATPIGDSAEANAIRVAGCEQAAVYAPKSALGHSIGA
MMAR_3338|M.marinum_M LSPKDIDHVNAHGTATPIGDSAEANAIRVAGCENAAIYAPKSALGHSIGA
MUL_1304|M.ulcerans_Agy99 LSPTDIDHVNAHGTATPIGDSAEANAIRVAGFENAAIYAPKSALGHSIGA
MAV_2192|M.avium_104 LSPKDVDHVNAHGTATPIGDTAEANAIRVAGCQEAAVYAPKSALGHSIGA
MAB_1877c|M.abscessus_ATCC_199 LSPKDIDHINAHGTATPIGDVAEANAIHVAGVQHAAVYAPKSALGHSIGA
*.. *:.*:***.*.*.*** *****::*** :.*.:*************
Mvan_3756|M.vanbaalenii_PYR-1 VGALESALTVLALRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYQYAIN
MSMEG_4327|M.smegmatis_MC2_155 VGALESILTVLALRDGVIPPTLNYETPDPEIDLDIVAGEPRYGEYKYAIN
Mflv_2777|M.gilvum_PYR-GCK VGALESILTVLALRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYKYAIN
TH_3425|M.thermoresistible__bu VGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDIVAGEPRYGDYRYAIN
Mb2269|M.bovis_AF2122/97 VGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVN
Rv2245|M.tuberculosis_H37Rv VGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVN
MLBr_01655|M.leprae_Br4923 VGALESVLTVLALRDGVIPPTLNYQTPDPEIDLDIVAGEPRYGDYRYAIN
MMAR_3338|M.marinum_M VGALESALTVLSLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGEFQYAIN
MUL_1304|M.ulcerans_Agy99 VGALESALTVLSLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGEFQYAIN
MAV_2192|M.avium_104 VGALESVLTVLTLRDGVIPPTLNYETPDPEIDLDIVAGEPRYGDYQYAIN
MAB_1877c|M.abscessus_ATCC_199 VGALESVLTVLALRDGVIPPTLNLDNLDPEIDLDVVAGEPRHGDFKYAIN
****** ****:*********** :. *******:******:*:::**:*
Mvan_3756|M.vanbaalenii_PYR-1 NSFGFGGHNVALAFGRY
MSMEG_4327|M.smegmatis_MC2_155 NSFGFGGHNVALAFGRY
Mflv_2777|M.gilvum_PYR-GCK NSFGFGGHNVALAFGRY
TH_3425|M.thermoresistible__bu NSFGFGGHNVALAFGRY
Mb2269|M.bovis_AF2122/97 NSFGFGGHNVALAFGRY
Rv2245|M.tuberculosis_H37Rv NSFGFGGHNVALAFGRY
MLBr_01655|M.leprae_Br4923 NSFGFGGHNVALAFGRY
MMAR_3338|M.marinum_M NSFGFGGHNVALAFGRY
MUL_1304|M.ulcerans_Agy99 NSFGFGGHNVALAFGRY
MAV_2192|M.avium_104 NSFGFGGHNVALAFGRY
MAB_1877c|M.abscessus_ATCC_199 NSFGFGGHNVALAFGKY
***************:*