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M. abscessus ATCC 19977 MAB_4344c (-)

annotation: putative NAD-dependent glutamate dehydrogenase
coordinates: 4423715 - 4427026
length: 1103

ITTSSCGVVLPAGYIGEAERYPEVDTATLDLLAADGFEFRIRRGDNGQLRVTLYTAEGTVSLERVLSLLA
SCDLDVVSQVAMTIRRPDALLCTVHEFEAEPKHEPAVNLWNDDSTYRPMTAAMSAMWAGWVEVDRLAVLT
VSAGLSWQDTALLRAYGRFLRHTVVPLSQNRIHAVLLSHPEVSAALVELFHRQFDPALCSSDDVRAKRVD
QQLARVKEQLEQVSGLDAHRTLNAYLTLISATSRTNYYLSGGLGPDRNHISLKFRSEEIEELPRPRPPRE
IFVYSPEVEGVHIRFGQIARGGVRWSDRLDDYRTEVLGLAKAQSVKNAVIVPAGAKGGFVVRRPPSPTGN
LQADHRAHEQAGRRCYRQFITGLLEITDNLSADGEPSHPGDVVCRDGFDPYLVVAADKGTATFADVANEI
AAEHEYWLGDAFASGGSVGYDHKKMGITAKGAWVSVRRHLSEMEIDVDRDSFAVAGIGDMSGDVFGNAML
LSRSLALVAAFDHRHVFIDPAPDVERSWHERRRLFELPGSSWADYAPHAISAGGGVWPRDIKSIPVSDQM
RAVLGLGPEVSVLTPPAMIQAILSAPVDLLFNGGIGTYVKSSGESHLAAGDKANDIVRVDANALRCRVIA
EGGNLGLTSLARIEYARSGGRINTDALDNSAGVDCSDREVNIKILLGGAIQDGPGASSDRSQFLASLTDE
VSRLVLRDNAGQNRLLGEARSHAHLQIDVHGRMINDLVARRGLDRELEALPGPEELGVLAAEGKGLTSPE
LATLLAHAKLDLKAGLTQCGAFAGPVFSDLMAGYFPVRLADVVAVDVHPLRNEILATELVNDIFEMGGIT
YAHRLWEETGATPEDILRAFVVVTEVFDIRQLWDDIVAEQARPAVEYSMIAEVRRLLDRASRWFLANRQQ
PLAVDAEIARFRDHIRKHSGLVSDLLCGNELAAMRLIREEFVTKGIGDSTAKRLADGLYRYSLLDIIEVA
SETGLTVEMVASTYFTLSDRLDIDRWLIAVSALPRRDRWHTLARLTLREDLYRSVRLLTRDVVTEAAVGG
NADRLIAEWERDNWAHVQRAGARLEELAGKASHDVASLSVAARYVRSMANLS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4344c--100% (1103)putative NAD-dependent glutamate dehydrogenase
M. abscessus ATCC 19977MAB_1561-0.049.22% (1085) NAD-dependent glutamate dehydrogenase
M. abscessus ATCC 19977MAB_0820c-e-17639.10% (982) NAD-glutamate dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2503cgdh0.048.10% (1106) NAD-dependent glutamate dehydrogenase
M. gilvum PYR-GCKMflv_2569-0.048.37% (1102) NAD-glutamate dehydrogenase
M. tuberculosis H37RvRv2476cgdh0.048.10% (1106) NAD-dependent glutamate dehydrogenase
M. leprae Br4923MLBr_01249-0.048.83% (1067) hypothetical protein MLBr_01249
M. marinum MMMAR_3829gdh0.049.53% (1066) NAD-dependent glutamate dehydrogenase Gdh
M. avium 104MAV_1696-0.048.01% (1106) NAD-glutamate dehydrogenase
M. smegmatis MC2 155MSMEG_4699-0.048.01% (1131) NAD-glutamate dehydrogenase
M. thermoresistible (build 8)TH_0917-0.054.00% (887) PROBABLE NAD-DEPENDENT GLUTAMATE DEHYDROGENASE GDH (NAD-GDH)
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4069-0.049.17% (1090) NAD-glutamate dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2503c|M.bovis_AF2122/97           ---------------MTIDPGAKQDVEAWTTFTASADIPDWISKAYIDSY
Rv2476c|M.tuberculosis_H37Rv        ---------------MTIDPGAKQDVEAWTTFTASADIPDWISKAYIDSY
MMAR_3829|M.marinum_M               ---------------MTIDPGAKQDVGAWTAFTQPADIPDWISQAYLDSY
MAV_1696|M.avium_104                MFERIDNRRQLGAIGMTIDPRAQQDLKPWTTFTRQQDIPEWISKAYVESY
MLBr_01249|M.leprae_Br4923          ---------------MTIDPGATHVAELCTTFTQGADVPDWISKAYIDSY
Mflv_2569|M.gilvum_PYR-GCK          ---------------MSLNPGAVN---GATG-AVGAEMVERLIPAYLATY
Mvan_4069|M.vanbaalenii_PYR-1       ---------------MSLNPGAIN---GSVGPEVSSEVIDRLLPAYLATY
MSMEG_4699|M.smegmatis_MC2_155      -------------------------------------MIRRLSVAFLSTY
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           -RGPRDDS--SEATKAAEASWLPASLLTPAMLGAHYRLGRHRAAGESCVA
Rv2476c|M.tuberculosis_H37Rv        -RGPRDDS--SEATKAAEASWLPASLLTPAMLGAHYRLGRHRAAGESCVA
MMAR_3829|M.marinum_M               QRRGEEDS--QASQRAAEA---AASVVTPAMLSAHYRLGQHRPIGESRVA
MAV_1696|M.avium_104                RGPHSDES--GGAEAGPIDLTVPTAIVTPAMLSAHYRLGLHRPDGESRVA
MLBr_01249|M.leprae_Br4923          RGSHGDVR--EAPETSRVN---PNALVTPAMLSAHYRLGQCRPNGRNCVR
Mflv_2569|M.gilvum_PYR-GCK          RGPHGGAPGADAAVTGPLRRH-DDGLDTTALVEAQCRLAGTRLPGATNVA
Mvan_4069|M.vanbaalenii_PYR-1       RGPHGGAPGAESAVTGPLRRQGTDTVNGPALVAAHYRLGAQRSPGATRVA
MSMEG_4699|M.smegmatis_MC2_155      RGPQADAPGVTS--TGPLAVAAHDDLVSDDLVAAHYRLASMRAPGETKAA
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           VYRADDPAGFGPALQVVAEHGGMLMDSVTVLLHRLGIAYAAILTPVFDVH
Rv2476c|M.tuberculosis_H37Rv        VYRADDPAGFGPALQVVAEHGGMLMDSVTVLLHRLGIAYAAILTPVFDVH
MMAR_3829|M.marinum_M               VYPADDPVGFGPALQVVTEHGSMLMDSVTVLLHRLGVGYTTIMTPVFEVH
MAV_1696|M.avium_104                VYPADDPAGFGPALQVVTDHGGMLMDSVTVLLHRLGVPYTAIMTPVFDVH
MLBr_01249|M.leprae_Br4923          VYPADDPAGFGPALQIVTDHGGMVMDSITVLLHRLGVTYTAMMTPVFMVL
Mflv_2569|M.gilvum_PYR-GCK          VYPGDEATGFGPALQIVTDNASLLMDSVTVLLHRIGVAYTAIMNPGFRVR
Mvan_4069|M.vanbaalenii_PYR-1       VHAADVEGGFGPALQVVTDNAAILMDSITVLLHRIGVAYTAIMNPVFRVR
MSMEG_4699|M.smegmatis_MC2_155      VYPGDAGS--GAALQIVTDQAPMLVDSVTVLLHRHGIAYTAIMNPVFRVR
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           RSPTGELLRIEPKAEGTSP-----HLGEAWMHVALSPAVDHKGLAEVERL
Rv2476c|M.tuberculosis_H37Rv        RSPTGELLRIEPKAEGTSP-----HLGEAWMHVALSPAVDHKGLAEVERL
MMAR_3829|M.marinum_M               RGPTGELQRVEPKSLDASP-----YVGEAWIHVQLSPTVEAKALAEVEQL
MAV_1696|M.avium_104                RSPDGDLLSLEPKPQGAPQ-----YAGEAWIHVQLLPSVDSKGLTEAERL
MLBr_01249|M.leprae_Br4923          RSPTGELLGVEPRASSTSHSIEGTWVGEVWIYIQLLPAVDSKSLAEVEQL
Mflv_2569|M.gilvum_PYR-GCK          RGGAGELLDVAPVSDASFSD----GVDETWVHVQLAGSVDRHALAEAEEL
Mvan_4069|M.vanbaalenii_PYR-1       RGAGGELQDIAPASDATFVD----GVDETWVHVQLADSVDRRALAEAEEL
MSMEG_4699|M.smegmatis_MC2_155      RGLDGELLDVRPAAEAAPGD----GADECWILVPITAAADGEALTEATRL
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           LPKVLADVQRVATDATALIATLSELAGEVESNAGGRFSAPDRQDVGELLR
Rv2476c|M.tuberculosis_H37Rv        LPKVLADVQRVATDATALIATLSELAGEVESNAGGRFSAPDRQDVGELLR
MMAR_3829|M.marinum_M               LPKVLADVQRVAKDAPAMIATLSELAVAVDSDREGHYAAPDHQEVAALLR
MAV_1696|M.avium_104                LPKVLADVQQVASDASALIAVLDELAAAVEANRDNHFSAPDRDDVAALLR
MLBr_01249|M.leprae_Br4923          LPRTLVDVQRVAADAAALNATLSGLAADVKTNKEGHFSASDRDDVAALLH
Mflv_2569|M.gilvum_PYR-GCK          LPKVLADARQVALDSTDMAAALRILAAELDGDTGRRFPSPDRKDVAALLR
Mvan_4069|M.vanbaalenii_PYR-1       LPRVLADARQVALDSTGMAAALRTLAAELDSDPGRRFPSPDRKDVAALLR
MSMEG_4699|M.smegmatis_MC2_155      VPGILAEARQIGLDSGAMIAALHGLANDLATDLEGHFPNAERKEVAALLR
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           WLGDGNFLLLGYQRCRVADGMVYGEGSSGMGVLRGRTGSRPRLTDDDKLL
Rv2476c|M.tuberculosis_H37Rv        WLGDGNFLLLGYQRCRVADGMVYGEGSSGMGVLRGRTGSRPRLTDDDKLL
MMAR_3829|M.marinum_M               WLGNGNFLLLGYQPCEVDDGMVLGDGSTGLGVLRARTGTRPRLTDETKLL
MAV_1696|M.avium_104                WLGNGNFLLLGYQRCRVHDGLVSGDGSPGLGVLRTRTGSRPRLTDDDRLL
MLBr_01249|M.leprae_Br4923          WLGNGNFLLLGYQRCRVHYGLVSCDRSTGLGVLRARTGSRPRLTDDNELL
Mflv_2569|M.gilvum_PYR-GCK          WLADGHFVLLGYQRCPVRDGEATVDTSSRLGVLRLRQDVLPQLTQKDELL
Mvan_4069|M.vanbaalenii_PYR-1       WLADGHFVLLGYQRCPVRDGEATVDPSSRLGVLRLREDVFPQLTNKDELL
MSMEG_4699|M.smegmatis_MC2_155      WLADGHFVLLGYQQCVVGDGNAEVDPASRLGVLRLRNDVLPPLTDSDDLL
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           VLAQARVGSYLRYGAYPYAIAVREYV------DGSVVEHRFVGLFSVAAM
Rv2476c|M.tuberculosis_H37Rv        VLAQARVGSYLRYGAYPYAIAVREYV------DGSVVEHRFVGLFSVAAM
MMAR_3829|M.marinum_M               VLAQARVGSYLRYGAYPYAIAIRESLG-----DGNIVEHRFVGLFTVAAM
MAV_1696|M.avium_104                VLAQSVVGSYLRYGAYPYAIAVREYV------DGAVIEHRFVGLFTVAAM
MLBr_01249|M.leprae_Br4923          VLAQAAVGNYLRYGAYPYAIAVREYDDG---GDGGIIEHRFVGLFTVAAM
Mflv_2569|M.gilvum_PYR-GCK          TLAQATIPSFLRYGAYPQIVVVREQSPERDAD---AIEHRFVGLFTVAAM
Mvan_4069|M.vanbaalenii_PYR-1       TLAQATIPSFLRYGTYPQIVVVREQSGDADADDAAAIEHRFVGMFTVAAM
MSMEG_4699|M.smegmatis_MC2_155      VLAQATMPSYLRYGAYPYIVVVRESPG---ASR--VIEHRFVGLFTVAAM
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           NADVLEIPTISRRVREALAMAESDPSHPGQLLLDVIQTVPRPELFTLSAQ
Rv2476c|M.tuberculosis_H37Rv        NADVLEIPTISRRVREALAMAESDPSHPGQLLLDVIQTVPRPELFTLSAQ
MMAR_3829|M.marinum_M               NADVLEIPAISHRVRDALELAGNDPSHPGQLLLDVIQTVPRPELFTLSSE
MAV_1696|M.avium_104                NADVLEIPTISRRVREALAMADSDPIHPGQLLLDVIQTVPRSELFTLSSE
MLBr_01249|M.leprae_Br4923          NADVLEIPSISHRVRAALAMANSDPIYPGQLLLDVIQTVPRSELFTLSAE
Mflv_2569|M.gilvum_PYR-GCK          NANVLEIPLVSRRVNDALAMAHRDPSHPGQLLLDIIQTIPRSELFALSAR
Mvan_4069|M.vanbaalenii_PYR-1       NANVLEIPLVSRRVNDALAMAHRDPSHPGQLVLDIIQTIPRSELFALSAR
MSMEG_4699|M.smegmatis_MC2_155      NANALEIPLISRRVEEALAMAHRDPSHPGQLLRDIIQTIPRPELFALSSK
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           RLLTMARAVVDLGSQRQALLFLRADRLQYFVSCLVYMPRDRYTTAVRMQF
Rv2476c|M.tuberculosis_H37Rv        RLLTMARAVVDLGSQRQALLFLRADRLQYFVSCLVYMPRDRYTTAVRMQF
MMAR_3829|M.marinum_M               QLLAMAKAVVDLGSQRRALLFLRVDRLQFFVSCLVYLPRDRYTTAVRLQI
MAV_1696|M.avium_104                RLLAMAKAVVDLGPQRNALLFLRADSLQYFVSCLVYLPRDRYTTAVRLQI
MLBr_01249|M.leprae_Br4923          RLFTMAKEVVDLGSGRRALLFLRADRLQYFVSCLVYVPRDRYTTGVRLQI
Mflv_2569|M.gilvum_PYR-GCK          GLLDMAMAVVDLGARRRTLLFMRADPLAHFVSCLVYLPRDRYTTVVRLEM
Mvan_4069|M.vanbaalenii_PYR-1       GLLDMAMAVVDLGSRRRALLFMRADPLAHFVSCLVYLPRDRYTTAVRLEM
MSMEG_4699|M.smegmatis_MC2_155      QLLEMALAVVDLGSRRRTLLFLRADHLAHFVSCLVYLPRDRYTTAVRLEM
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------MITTSSCGVVLP------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           EDILVREFGGTRLEFTARVSESPWALMHFMVRLPEVGVAGEGAAAPPVDV
Rv2476c|M.tuberculosis_H37Rv        EDILVREFGGTRLEFTARVSESPWALMHFMVRLPEVGVAGEGAAAPPVDV
MMAR_3829|M.marinum_M               EDILVREFGGTRLEFTARVSESPWALMHFMVRLPEDVATGS------IDV
MAV_1696|M.avium_104                EDILVREFGGTRLEFTARVSESPWALMHFMVRLPTDDPAAK-----PVDV
MLBr_01249|M.leprae_Br4923          EDILVREFGGTQVEFTARVSESPWALMHFMVRLSEGAATGS------VDV
Mflv_2569|M.gilvum_PYR-GCK          QDILVRELGGVSIDYAARVSESPWAVVHFTVRLPAGLRQHE------VDV
Mvan_4069|M.vanbaalenii_PYR-1       QDILVRELGGVSIDYAARVSESPWAVVHFTVRMPEGSRPQD------IDV
MSMEG_4699|M.smegmatis_MC2_155      QDILVRELGGAGIDYSARVSESPWAVVHFTVRLPEGTAADS------VDT
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb2503c|M.bovis_AF2122/97           SEANRIRIQGLLTEAARTWADRLIG-AAAAG--SVGQADAMHYAAAFSEA
Rv2476c|M.tuberculosis_H37Rv        SEANRIRIQGLLTEAARTWADRLIGAAAAAG--SVGQADAMHYAAAFSEA
MMAR_3829|M.marinum_M               SEANRSRIQALLSEAARTWADRLIG-AASDA--SVRHADAEHYAAAFPEA
MAV_1696|M.avium_104                SEDNRVRIQGLLSEAARTWTDRLVA-AAAEG--AVGHADAEYYADAFPEV
MLBr_01249|M.leprae_Br4923          SEGNRIRIQAMLSEAARTWSDRLIAAAASFSEGSVSYAEAEHYAATFSET
Mflv_2569|M.gilvum_PYR-GCK          SDDNEARIQDLLTEAARTWGDRLMGALPAGG--PVDHGTADHYASAFPEV
Mvan_4069|M.vanbaalenii_PYR-1       SEPNESRIQDLLTEAARTWSDRLLGAVSAGG--EVDQATAEHYASAFSEV
MSMEG_4699|M.smegmatis_MC2_155      SLENESRIQDLLTEATRNWGDRMISAAAAA---SISPAALEHYAHAFPED
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      --------AGYIGEAER-----------------------------YPEV
                                                                                      

Mb2503c|M.bovis_AF2122/97           YKQAVTPADAIGDIAVITELTDDSVKLVFSER---DEQGVAQLTWFLGGR
Rv2476c|M.tuberculosis_H37Rv        YKQAVTPADAIGDIAVITELTDDSVKLVFSER---DEQGVAQLTWFLGGR
MMAR_3829|M.marinum_M               YKQAVAPADAIDHIAIINELADDSVKLVFSDR---TADGVAQLTWFLGGC
MAV_1696|M.avium_104                YKQAISPADAIGHIAIIKELQDNSVKLVFTD----GEDGSAQLTWFLGGR
MLBr_01249|M.leprae_Br4923          YKQAVTPADAIDHIAIIKELADDSVKLVFFER---KADGFAQLTWFLGGR
Mflv_2569|M.gilvum_PYR-GCK          YKQANTPARALDDIAIIEELHDNTVKLVLADSDDTETSGVSDLNWYLGGQ
Mvan_4069|M.vanbaalenii_PYR-1       YKQAIDPVHALADIAVIEELQDNSVKLVLADSDDTAESGVSHLNWYLGGR
MSMEG_4699|M.smegmatis_MC2_155      YKQAFAPQDAIADISLIEALQDDSVKLVLAD---TAEDRVWKLTWYLGGH
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      ------------DTATLDLLAADGFEFRIRRG----DNGQLRVTLYTAEG
                                                                                      

Mb2503c|M.bovis_AF2122/97           TASLSQLLPMLQSMGVVVLEERPFSVTRPDGLPVWIYQFKISPHPTIPLA
Rv2476c|M.tuberculosis_H37Rv        TASLSQLLPMLQSMGVVVLEERPFSVTRPDGLPVWIYQFKISPHPTIPLA
MMAR_3829|M.marinum_M               TASLSQLLPMLQSMGVVVLEERPFTVTRPDGLPVWIYQFKISPHPTIPKA
MAV_1696|M.avium_104                TASLSQLLPMLQSMGVVVLEERPFTVTRSDGLPVWIYQFRISPHPTIELA
MLBr_01249|M.leprae_Br4923          SASLSQLLPMLQSMGVVVLEERPFTVARTDGLPVWIYQFKISPHPTIPLA
Mflv_2569|M.gilvum_PYR-GCK          SASLSRLLPMLQSMGVVVLEERPFTVTRPDGLPVWIYQFKVSPHRGIPQA
Mvan_4069|M.vanbaalenii_PYR-1       SASLSRLLPMLQSMGVVVLEERPFTVVRPDGLPVWIYQFKVSPHRGIPEA
MSMEG_4699|M.smegmatis_MC2_155      SASLSELLPMLQSMGVVVLEERPFTLRRTDGLPVWIYQFKISPHPSIPHA
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      TVSLERVLSLLASCDLDVVSQVAMTIRRPDALLCTVHEFEAEPKHEP--A
                                                                                      

Mb2503c|M.bovis_AF2122/97           PTVAERAATAHRFAEAVTAIWHGRVEIDRFNELVMRAGLTWQQVVLLRAY
Rv2476c|M.tuberculosis_H37Rv        PTVAERAATAHRFAEAVTAIWHGRVEIDRFNELVMRAGLTWQQVVLLRAY
MMAR_3829|M.marinum_M               TVPAERAAAAQRFADAVTAIWQGRIEIDRFNELVMRAGLTWQQVVLLRAY
MAV_1696|M.avium_104                STPDERDAMAERFADAVTAIWQGRLEVDRFNELVMRAGLRWQQVVLLRAY
MLBr_01249|M.leprae_Br4923          STANERELTAKRFSDAVTAIWQGRVEIDRFNELVMRARLTWQQVVLLRAY
Mflv_2569|M.gilvum_PYR-GCK          PPGPERDATAERFADTVTAIWHGNAEIDRFNELVLRAGLTWQQVAVLRAY
Mvan_4069|M.vanbaalenii_PYR-1       PPGPQREATAERFADAVTAIWHGNAEIDRFNELVLRAELTWQQVAVLRAY
MSMEG_4699|M.smegmatis_MC2_155      PDAEAQRDTAQRFADAVTAIWHGRVEIDRFNELVMRAGLTWQQVVVLRAY
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      VNLWNDDSTYRPMTAAMSAMWAGWVEVDRLAVLTVSAGLSWQDTALLRAY
                                                                                      

Mb2503c|M.bovis_AF2122/97           AKYLRQAGFPYSQSYIESVLNEHPATVRSLVDLFEALFVP--VPSGSASN
Rv2476c|M.tuberculosis_H37Rv        AKYLRQAGFPYSQSYIESVLNEHPATVRSLVDLFEALFVP--VPSGSASN
MMAR_3829|M.marinum_M               SRYLRQAGFPYSQSYIESVLNEHPSTARSLVLLFEALFDP--RPAGSPVS
MAV_1696|M.avium_104                AKYLRQANFPYSQSYIEAVLNEHPSTARSLVALFEALFDP--DPD-SSAG
MLBr_01249|M.leprae_Br4923          AKYLRQAGFNYSQSYIESVLNEHPSTARSLVALFEALFDP--SPLSSSTN
Mflv_2569|M.gilvum_PYR-GCK          AKYLKQAGFPYSQSHIASVLNDNAGTARSLVELFEALYSPV-DGNPGGAN
Mvan_4069|M.vanbaalenii_PYR-1       ARYLKQAGFAYSQSHIESVLNDNAGTARSLIALFEALFRPV-EQGPG-AN
MSMEG_4699|M.smegmatis_MC2_155      AKYLRQAGFPYSQSHIESVLNENPHTTRSLIDLFEALFDPS-QETDG--R
TH_0917|M.thermoresistible__bu      --------------------------------------------------
MAB_4344c|M.abscessus_ATCC_199      GRFLRHTVVPLSQNRIHAVLLSHPEVSAALVELFHRQFDPALCSSDDVRA
                                                                                      

Mb2503c|M.bovis_AF2122/97           RDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTRQGSAR
Rv2476c|M.tuberculosis_H37Rv        RDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTRQGSAR
MMAR_3829|M.marinum_M               PDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVSREGSAR
MAV_1696|M.avium_104                RDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTREGSAR
MLBr_01249|M.leprae_Br4923          CDAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTQKFSAR
Mflv_2569|M.gilvum_PYR-GCK          RDAQSAAAAVAADIDALVSLDTDRVLRAFASMIQATLRTNYFVTAADSAR
Mvan_4069|M.vanbaalenii_PYR-1       RDAQAAAAAVAADIDALVSLDTDRVLRAFASMIQATLRTNYFITGQESAR
MSMEG_4699|M.smegmatis_MC2_155      RDAQGAAAAVAADIDALVSLDTDRVLRAFANLIEATLRTNYFVARPDSAR
TH_0917|M.thermoresistible__bu      ----------------VVSLDTDRVLRAFASLIEATLRTNYFVSRDDSDR
MAB_4344c|M.abscessus_ATCC_199      KRVDQQLARVKEQLEQVSGLDAHRTLNAYLTLISATSRTNYYLSG-GLGP
                                                    : .**:.* *.*: .::.** ****:::      

Mb2503c|M.bovis_AF2122/97           CRDVLALKLNAQLIDELPLPRPRYEIFVYSPRVEGVHLRFGPVARGGLRW
Rv2476c|M.tuberculosis_H37Rv        CRDVLALKLNAQLIDELPLPRPRYEIFVYSPRVEGVHLRFGPVARGGLRW
MMAR_3829|M.marinum_M               SRDVLSVKLDAQLIDELPLPRPKYEIFVYSPRVEGVHLRFGPVARGGLRW
MAV_1696|M.avium_104                ARNVLVIKLDAQLIDELPLPRPKYEIFVYSPRVEGVHLRFGPVARGGLRW
MLBr_01249|M.leprae_Br4923          SKGVLVLKLDAQLINELPLPRPKFEIFVYSPRVEGVHLRFGAVARGGLRW
Mflv_2569|M.gilvum_PYR-GCK          ARNVLSFKLNPELIDELPLPRPKFEIFVYSPRVEGVHLRFGFVARGGLRW
Mvan_4069|M.vanbaalenii_PYR-1       ARNVLSLKLNPQLIDELPLPRPKFEIFVYSPRVEGVHLRFGFVARGGLRW
MSMEG_4699|M.smegmatis_MC2_155      ARNVLAFKLNPLVIKELPLPRPKFEIFVYSPRVEGVHLRFGFVARGGLRW
TH_0917|M.thermoresistible__bu      ARGVFSVKLRPALIKELPLPRPMFEIFVYSPRVEGVHLRFGHVARGGLRW
MAB_4344c|M.abscessus_ATCC_199      DRNHISLKFRSEEIEELPRPRPPREIFVYSPEVEGVHIRFGQIARGGVRW
                                     :. : .*: .  *.*** ***  *******.*****:*** :****:**

Mb2503c|M.bovis_AF2122/97           SDRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLPTGDPAADR
Rv2476c|M.tuberculosis_H37Rv        SDRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLPTGDPAADR
MMAR_3829|M.marinum_M               SDRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLSTGDAATDR
MAV_1696|M.avium_104                SDRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLPSGDGAADR
MLBr_01249|M.leprae_Br4923          SDRLDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVLKRPPLPTGDAAADR
Mflv_2569|M.gilvum_PYR-GCK          SDRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKKPPAPTGDAAADR
Mvan_4069|M.vanbaalenii_PYR-1       SDRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKHPPAPTGDAAADR
MSMEG_4699|M.smegmatis_MC2_155      SDRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPTLTGDAAADR
TH_0917|M.thermoresistible__bu      SDRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPAPTGDAAADR
MAB_4344c|M.abscessus_ATCC_199      SDRLDDYRTEVLGLAKAQSVKNAVIVPAGAKGGFVVRRPPSPTGNLQADH
                                    *** :*:***:***.***:********.*******:::**  :*:  :*:

Mb2503c|M.bovis_AF2122/97           DATRAEGVACYQLFISGLLDVTDNVDHATASVNPPPEVVRRDGDDAYLVV
Rv2476c|M.tuberculosis_H37Rv        DATRAEGVACYQLFISGLLDVTDNVDHATASVNPPPEVVRRDGDDAYLVV
MMAR_3829|M.marinum_M               EATRAEGVACYQLFISGLLDVTDNVDHTTGVVSPPPEVLRRDGDDAYLVV
MAV_1696|M.avium_104                DATRAEGVACYQLFISGLLDVTDNVDHATGKVSPPPEVVRRDGDDAYLVV
MLBr_01249|M.leprae_Br4923          DAMRAEGIACYQLFISGLLDITDNVDHATGKVNAPPQVVRRDSDDAYLVV
Mflv_2569|M.gilvum_PYR-GCK          DATREEGVACYRLFIAGLLDITDNVDKISGDVVTPAEVVRRDGDDAYLVV
Mvan_4069|M.vanbaalenii_PYR-1       DATREEGVACYRLFIAGLLDITDNVDKVTGGIVAPADVVRRDGDDAYLVV
MSMEG_4699|M.smegmatis_MC2_155      EATRAEGVECYRLFISGLLDVTDNVDKATGAVVTPPEVVRRDGEDAYLVV
TH_0917|M.thermoresistible__bu      EAARAEGIACYRLFVSGLLDITDNVDKTTGAVVPPAEVVRRDGDDAYLVV
MAB_4344c|M.abscessus_ATCC_199      RAHEQAGRRCYRQFITGLLEITDNLS-ADGEPSHPGDVVCRDGFDPYLVV
                                     * .  *  **: *::***::***:.   .    * :*: **. *.****

Mb2503c|M.bovis_AF2122/97           AADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITARGAWE
Rv2476c|M.tuberculosis_H37Rv        AADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITARGAWE
MMAR_3829|M.marinum_M               AADKGTATFSDIANEVANSYGFWLGDAFASGGSVGYDHKAMGITAKGAWE
MAV_1696|M.avium_104                AADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITARGAWE
MLBr_01249|M.leprae_Br4923          AADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGAWE
Mflv_2569|M.gilvum_PYR-GCK          AADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGAWE
Mvan_4069|M.vanbaalenii_PYR-1       AADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGAWE
MSMEG_4699|M.smegmatis_MC2_155      AADKGTATFSDIANEVAKSYGFWLGDAFASGGSIGYDHKAMGITAKGAWE
TH_0917|M.thermoresistible__bu      AADKGTATFSDIANEVAQSYGFWLGDAFASGGSVGYDHKAMGITARGAWE
MAB_4344c|M.abscessus_ATCC_199      AADKGTATFADVANEIAAEHEYWLGDAFASGGSVGYDHKKMGITAKGAWV
                                    *********:*:**::* .: :***********:***** *****:*** 

Mb2503c|M.bovis_AF2122/97           AVKRHFREIGIDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFDHR
Rv2476c|M.tuberculosis_H37Rv        AVKRHFREIGIDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFDHR
MMAR_3829|M.marinum_M               AVKRHFREMGIDTQTEDFTVVGVGDMSGDVFGNGMLLSKHIRLIAAFDHR
MAV_1696|M.avium_104                AVKRHFREMGVDTQTEDFTVVGIGDMSGDVFGNGMLLSKHIRLLAAFDHR
MLBr_01249|M.leprae_Br4923          AVKRHFREMGVDTQNEDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFDHR
Mflv_2569|M.gilvum_PYR-GCK          SVKRHFREMGIDTQSEDFTVVGVGDMSGDVFGNGMLLSEHIRLLAAFDHR
Mvan_4069|M.vanbaalenii_PYR-1       SVKRHFREMGVDTQSEDFTVVGVGDMSGDVFGNGMLLSKHIRLLAAFDHR
MSMEG_4699|M.smegmatis_MC2_155      SVKRHFREMGVDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLVAAFDHR
TH_0917|M.thermoresistible__bu      SVKRHFREMGVDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLVAAFDHR
MAB_4344c|M.abscessus_ATCC_199      SVRRHLSEMEIDVDRDSFAVAGIGDMSGDVFGNAMLLSRSLALVAAFDHR
                                    :*:**: *: :*.: :.*:*.*:**********.****. : *:******

Mb2503c|M.bovis_AF2122/97           HIFLDPNPDAAVSWAERRRMFELPRSSWGDYDRSLISEGGGVYSREQKAI
Rv2476c|M.tuberculosis_H37Rv        HIFLDPNPDAAVSWAERRRMFELPRSSWSDYDRSLISEGGGVYSREQKAI
MMAR_3829|M.marinum_M               HVFLDPNPDAAASWQERQRMFDLPRSSWDDYNKSLISEGGGVYSREQKSI
MAV_1696|M.avium_104                HIFLDPNPDAAASWEERRRMFELPRSSWDDYDKSLISEGGGVYSREHKSI
MLBr_01249|M.leprae_Br4923          HVFLDPDPDAAVSWAERQRMFDLPRSSWDDYNKSLISEGGGVYSREQKAI
Mflv_2569|M.gilvum_PYR-GCK          HIFIDPTPDAASSYAERRRLFDLPRSSWDDYDKSLISAGGGVYSREQKSI
Mvan_4069|M.vanbaalenii_PYR-1       HIFIDPTPDAASSWEERKRLFELPRSSWEDYDTSLISPGGGVYSREQKSI
MSMEG_4699|M.smegmatis_MC2_155      DIFLDPNPDAGRSWDERKRLFDLPRSSWADYDKSLISEGGGVYSRQQKSI
TH_0917|M.thermoresistible__bu      HIFLDPDPDPARSWEERKRLFELPRSSWDDYDTSVISRGGGVYSRQQKSI
MAB_4344c|M.abscessus_ATCC_199      HVFIDPAPDVERSWHERRRLFELPGSSWADYAPHAISAGGGVWPRDIKSI
                                    .:*:** **   *: **:*:*:** *** **    ** ****:.*: *:*

Mb2503c|M.bovis_AF2122/97           PLSAQVRAVLGIDGSVDGGAAEMAPPNLIRAILRAPVDLLFNGGIGTYIK
Rv2476c|M.tuberculosis_H37Rv        PLSAQVRAVLGIDGSVDGGAAEMAPPNLIRAILRAPVDLLFNGGIGTYIK
MMAR_3829|M.marinum_M               PVSDQVRNALGIGGDVT----EMTPPNLIRAILQAPVDLLFNGGIGTYIK
MAV_1696|M.avium_104                PVSPQVRDALGLDGSGGGVVTEMTPPNLIKAILQAPVDLLFNGGIGTYIK
MLBr_01249|M.leprae_Br4923          PTSPQVRTALGIDGEVT----EMAPPNLIRAILQAPVDLLFNGGIGTYIK
Mflv_2569|M.gilvum_PYR-GCK          PISDEARAALGIEGDAT----EMTPPALMKAILKAPADLLWNGGIGTYIK
Mvan_4069|M.vanbaalenii_PYR-1       PVSAQARAALGLDDQVT----DLTPPALMKAILKAPADLLWNGGIGTYVK
MSMEG_4699|M.smegmatis_MC2_155      PISPQVRTALGLDADVE----ELTPPALIKAILKAPVDLLWNGGIGTYIK
TH_0917|M.thermoresistible__bu      PVSAEVRAALGLDGDVD----ALTPPAMIRAILRAPVDLLFNGGIGTYIK
MAB_4344c|M.abscessus_ATCC_199      PVSDQMRAVLGLGPEVS----VLTPPAMIQAILSAPVDLLFNGGIGTYVK
                                    * * : * .**:  .       ::** :::*** **.***:*******:*

Mb2503c|M.bovis_AF2122/97           AESESDADVGDRANDPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLSGG
Rv2476c|M.tuberculosis_H37Rv        AESESDADVGDRANDPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLSGG
MMAR_3829|M.marinum_M               AESESDADVGDRANNPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLSGG
MAV_1696|M.avium_104                AESESDADVGDRANDPVRVNGSSVRAKVIGEGGNLGVTALGRVEFDLSGG
MLBr_01249|M.leprae_Br4923          AETESVADVGDRANDPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLSGG
Mflv_2569|M.gilvum_PYR-GCK          AETEADADVGDRANDPVRVNGNQVRAKVVGEGGNLGVTSLGRTEFDLCGG
Mvan_4069|M.vanbaalenii_PYR-1       AETEADADVGDRANDAVRVNGNEVRAKVIGEGGNLGVTSRGRTEFDLCGG
MSMEG_4699|M.smegmatis_MC2_155      AETEADADVGDRANDQIRVCGNQVRAKVIGEGGNLGVTALGRIEFDLAGG
TH_0917|M.thermoresistible__bu      AESESDADVGDRANDPVRVNGNQVRAKVIGEGGNLGVTPLGRVEYDLAGG
MAB_4344c|M.abscessus_ATCC_199      SSGESHLAAGDKANDIVRVDANALRCRVIAEGGNLGLTSLARIEYARSGG
                                    :. *:   .**:**: :** .. :*.:*:.******:*. .* *:  .**

Mb2503c|M.bovis_AF2122/97           RINTDALDNSAGVDCSDHEVNIKILIDSLVSAGTVKADERTQLLESMTDE
Rv2476c|M.tuberculosis_H37Rv        RINTDALDNSAGVDCSDHEVNIKILIDSLVSAGTVKADERTQLLESMTDE
MMAR_3829|M.marinum_M               RINTDALDNSAGVDCSDHEVNIKILIDSLVSAGKVRTDERKQLLESMTDE
MAV_1696|M.avium_104                RINTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVKPQERKPLLESMTDE
MLBr_01249|M.leprae_Br4923          RINTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVKVEERKHLLESMTDE
Mflv_2569|M.gilvum_PYR-GCK          RINTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVAEADRTELLLSMTDE
Mvan_4069|M.vanbaalenii_PYR-1       RINTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVEESGRSALLSSMTDE
MSMEG_4699|M.smegmatis_MC2_155      RINTDALDNSAGVDCSDHEVNIKILIDSAVTAGKVTPEERTELLLSMTDE
TH_0917|M.thermoresistible__bu      RINTDALDNSAGVDCSDHEVNIKILIDSLVAAGKIGADQRTDLLMSMTDE
MAB_4344c|M.abscessus_ATCC_199      RINTDALDNSAGVDCSDREVNIKILLGGAIQDGPGASSDRSQFLASLTDE
                                    ******:**********:*******:.. :  *      *. :* *:***

Mb2503c|M.bovis_AF2122/97           VAQLVLADNEDQNDLMGTSRANAASLLPVHAMQIKYLVAERGVNRELEAL
Rv2476c|M.tuberculosis_H37Rv        VAQLVLADNEDQNDLMGTSRANAASLLPVHAMQIKYLVAERGVNRELEAL
MMAR_3829|M.marinum_M               VAQLVLTDNSDQNDLMGTSRANPVSLLPVHADQIRYLVAERGISRELEAL
MAV_1696|M.avium_104                VAALVLTDNEDQNDLIGTSRANAPSLLPVHARQIQYLVDERGLNRELEAL
MLBr_01249|M.leprae_Br4923          VARLVLTDNEDQNDLIGTSRANAANMLSVHAMQIKYLVDERGVNRELEAL
Mflv_2569|M.gilvum_PYR-GCK          VGRLVLADNESQNDLMGTSRANAASLLNVHARMIKDFVERRGLNRELEAL
Mvan_4069|M.vanbaalenii_PYR-1       VGRLVLADNESQNDLMGTSRANAASLLNVHGRMIRSFVEERGLNRELEAL
MSMEG_4699|M.smegmatis_MC2_155      VGELVLADNRDQNDLMGTSRANAASLLSVHARMIKDLVDNRGLNRELEAL
TH_0917|M.thermoresistible__bu      VADMVLAHNARQNDLIGTSRANTAAMLTVHARLIDDLVENHGVNRELEAL
MAB_4344c|M.abscessus_ATCC_199      VSRLVLRDNAGQNRLLGEARSHAHLQIDVHGRMINDLVARRGLDRELEAL
                                    *. :** .*  ** *:* :*::.   : **.  *  :* .:*:.******

Mb2503c|M.bovis_AF2122/97           PSEKEIARRSEAGIGLTSPELATLMAHVKLGLKEEVLATELPDQDVFASR
Rv2476c|M.tuberculosis_H37Rv        PSEKEIARRSEAGIGLTSPELATLMAHVKLGLKEEVLATELPDQDVFASR
MMAR_3829|M.marinum_M               PSEKEIARRSEAGIGLTSPELATLMAHVKLALKETMLTTELPDQDVFASR
MAV_1696|M.avium_104                PSEKEIQRRAEAGIGLTSPELCTLMAHVKLDLKEQMLQTELTEQDVFASR
MLBr_01249|M.leprae_Br4923          PSEKEIQRRSEAGIGLTSPELSTLMAHVKLALKEQMLATELPDQDVFVSR
Mflv_2569|M.gilvum_PYR-GCK          PSEKEILRRTEAGLGLTSPELATLMAHVKLALKDDLLAGELPDQEVFASR
Mvan_4069|M.vanbaalenii_PYR-1       PSEKEIRRREEAGIGLTSPELATLMAHVKLALKDDLLAGDLPDQEVFASR
MSMEG_4699|M.smegmatis_MC2_155      PSEKEIRRRADAGIGLTSPELATLMAHVKLALKDDVLASDLPDQEVFASR
TH_0917|M.thermoresistible__bu      PSDKEIARRSDTGVGLTSPELATVMAHVKLTLKDALLASELPDQEVFAAR
MAB_4344c|M.abscessus_ATCC_199      PGPEELGVLAAEGKGLTSPELATLLAHAKLDLKAGLTQCGAFAGPVFSDL
                                    *. :*:      * *******.*::**.** **  :         **   

Mb2503c|M.bovis_AF2122/97           LPRYFPTALRERFTPEIRSHQLRREIVTTMLINDLVDTAGITYAFRIAED
Rv2476c|M.tuberculosis_H37Rv        LPRYFPTALRERFTPEIRSHQLRREIVTTMLINDLVDTAGITYAFRIAED
MMAR_3829|M.marinum_M               LPSYFPKPLRERFAPEIRSHQLRREIVTTMVINDLVDTAGITYAFRITED
MAV_1696|M.avium_104                LPLYFPTPLRHRFTPEIRAHQLRREIVATMLINELVDAAGISYAFRIVED
MLBr_01249|M.leprae_Br4923          LPRYFPKPLRERFTPEIRSHQLRREIVTTMLINDLVDTAGISYAFRIAED
Mflv_2569|M.gilvum_PYR-GCK          LPSYFPTTLRERFGPDIRSHQLRREIVTTMLVNDVVDTAGISYAYRVAED
Mvan_4069|M.vanbaalenii_PYR-1       LPSYFPATLRDQFSPEIRAHQLRREIVTTMLVNDVVDTAGISYAYRVTED
MSMEG_4699|M.smegmatis_MC2_155      LPYYFPTRLREELHGEIRSHQLRREIITTMLVNDLVDTAGISYAYRITED
TH_0917|M.thermoresistible__bu      LPSYFPRPLRD-FTAEIRGHQLRREIVSTMLVNDLVDTAGLTYAFRVCED
MAB_4344c|M.abscessus_ATCC_199      MAGYFPVRLADVVAVDV--HPLRNEILATELVNDIFEMGGITYAHRLWEE
                                    :. ***  * . .  ::  * **.**::* ::*::.: .*::**.*: *:

Mb2503c|M.bovis_AF2122/97           VGVTPIDAVRTYVATDAIFGVGHIWRRIRAANLP----IALSDRLTLDTR
Rv2476c|M.tuberculosis_H37Rv        VGVTPIDAVRTYVATDAIFGVGHIWRRIRAANLP----IALSDRLTLDTR
MMAR_3829|M.marinum_M               VGVSPIDAVRTYMATDAIFGVSHIWRRIRAEELP----VALSDRLTLDTR
MAV_1696|M.avium_104                VGVSAVDAVRTYVATDAIFGVGEIWRRIRAANLP----VALSDRLTLDTR
MLBr_01249|M.leprae_Br4923          IGVGPIDAIRTYVATDAIFGVGDVLRRIRAANLS----VVLSDRMTLDTR
Mflv_2569|M.gilvum_PYR-GCK          VGVAPIDAVRSFAAGDAIFGFGRVWRQIREAGANGVS-VAVTDRMTLDLR
Mvan_4069|M.vanbaalenii_PYR-1       VGVAPVDAVRSFVAADAIFGVGRVWRQIREAGANGVP-VAVTDRMTLDLR
MSMEG_4699|M.smegmatis_MC2_155      VGVGPVDAVRSYVAINAIFGIGDVWRRIRAAGDAGVP-TSVTDRMTLDLR
TH_0917|M.thermoresistible__bu      AGVEPVDAVRSFVAVDAIFRVGEIWHAIRTAGAEGVLPVAVSDRMTLDLR
MAB_4344c|M.abscessus_ATCC_199      TGATPEDILRAFVVVTEVFDIRQLWDDIVAEQAR----PAVEYSMIAEVR
                                     *. . * :*:: .   :* .  :   *            :   :  : *

Mb2503c|M.bovis_AF2122/97           RLIDRAGRWLLNYRPQPLAVGAEINRFAAMVKALTPRMSEWLRGDDKAIV
Rv2476c|M.tuberculosis_H37Rv        RLIDRAGRWLLNYRPQPLAVGAEINRFAAMVKALTPRMSEWLRGDDKAIV
MMAR_3829|M.marinum_M               RLIDRASRWLLNYRPQPLAVGAEINRFAAKVKALTPRMSEWLRGDDKAIV
MAV_1696|M.avium_104                RLIDRAGRWLLNYRPQPLAVGAEINRFAAKVKALTPRMSEWLRGDDKAIV
MLBr_01249|M.leprae_Br4923          RLIDRAGRWLLNYRPQPLAVGAEINRFAAKVKALTPRMSEWLRGDDQAIV
Mflv_2569|M.gilvum_PYR-GCK          RLIDRATRWLLNYRPLPLAVGAEINRFADKVAALTPSMPDWLRGDDKAIV
Mvan_4069|M.vanbaalenii_PYR-1       RLIDRAARWLLNYRPQPLAVGAEINRFADKVAALTPRMPDWLRGDDKAIV
MSMEG_4699|M.smegmatis_MC2_155      RLVDRAGRWLLNYRPQPLAVGAEINRFGAKVAALTPRMSEWLRGDDKAIV
TH_0917|M.thermoresistible__bu      RLIDRAARWLLNFRPQPLAVGAEINRFAAKVAALTPRMSEWLCGADADIV
MAB_4344c|M.abscessus_ATCC_199      RLLDRASRWFLANRQQPLAVDAEIARFRDHIRKHSGLVSDLLCGNELAAM
                                    **:*** **:*  *  ****.*** **   :   :  :.: * * :   :

Mb2503c|M.bovis_AF2122/97           EKTAAEFASQGVPEDLAYRVSTGLYRYSLLDIIDIADIADIDAAEVADTY
Rv2476c|M.tuberculosis_H37Rv        EKTAAEFASQGVPEDLAYRVSTGLYRYSLLDIIDIADIADIDAAEVADTY
MMAR_3829|M.marinum_M               EKTSEEFIAQGAPEDLAYRVAVGLYRYSLLDIIDIADIADIDAAEVADTY
MAV_1696|M.avium_104                EKEAAEFESQGAPRDLAYLVAAGLYRFSLLDIIDIGDINDIDAAEVADTY
MLBr_01249|M.leprae_Br4923          EQQATEFVSQGAPEDLAYRVAVGLYRYSLLDIIDIADITELDPAEVADTY
Mflv_2569|M.gilvum_PYR-GCK          EKEAGEFSAHGVAEDVAYTVATGLYQFSLLDVIDIADIIDRDPAEVADAY
Mvan_4069|M.vanbaalenii_PYR-1       AKEAAEFSSQGVPDDVAYMVASGLYQFSLLDVIDIADIVDRDPAEVADAY
MSMEG_4699|M.smegmatis_MC2_155      SKEAGDFASHGVPEDLAYHIATGLYQYSLLDVIDIADIVDREPDEVADTY
TH_0917|M.thermoresistible__bu      ARRTADFVEHGASRQLAYLVSSALYQFSLLDIIDIADILDREPAEVAETY
MAB_4344c|M.abscessus_ATCC_199      RLIREEFVTKGIGDSTAKRLADGLYRYSLLDIIEVASETGLTVEMVASTY
                                         :*  :*   . *  :: .**::****:*::..        **.:*

Mb2503c|M.bovis_AF2122/97           FALMDRLGTDGLLTAVSQLPRHDRWHSLARLAIRDDIYGALRSLCFDVLA
Rv2476c|M.tuberculosis_H37Rv        FALMDRLGTDGLLTAVSQLPRHDRWHSLARLAIRDDIYGALRSLCFDVLA
MMAR_3829|M.marinum_M               FALVDRLGADGLLTAVSELPRKDRWHSLARLAIRDDIYGALRSLCFDVIA
MAV_1696|M.avium_104                FALMDRLGTDGLLTAVSELPRNDRWHSLARLAICDDIYASLRSLCFDVLA
MLBr_01249|M.leprae_Br4923          FSLMDRLGTDGLLTAVSKLPQNDRWHSLARLAIRDDIYASLRSLCFDVLA
Mflv_2569|M.gilvum_PYR-GCK          FALMDHLGTDGLLTAVSRLSRNDRWHSLARLAIRDDIYGSLRALCFDVLA
Mvan_4069|M.vanbaalenii_PYR-1       FALMDHLGTDGLLTAVSRLSRYDRWHSLARLAIRDDIYGSLRALCFDVLA
MSMEG_4699|M.smegmatis_MC2_155      FALMDHLGADALLTAVSRLSRDDRWHSLARLAIRDDIYGSLRALCFDVLA
TH_0917|M.thermoresistible__bu      FALMGHLNADALLTAVSELPRSDRWHSLARLAIRDDIYGSLRLLTVDVLA
MAB_4344c|M.abscessus_ATCC_199      FTLSDRLDIDRWLIAVSALPRRDRWHTLARLTLREDLYRSVRLLTRDVVT
                                    *:* .:*. *  * *** *.: ****:****:: :*:* ::* *  **::

Mb2503c|M.bovis_AF2122/97           VGEPGESSEQKIAEWEHLSASRVARARRTLDDIRASGQKDLATLSVAARQ
Rv2476c|M.tuberculosis_H37Rv        VGEPGESSEQKIAEWEHLSASRVARARRTLDDIRASGQKDLATLSVAARQ
MMAR_3829|M.marinum_M               VGEPDESSEQKILEWEQLSASRVDRARRTLNEIRDSGQKDLATLSVAARQ
MAV_1696|M.avium_104                VGEPDESGEEKIAEWEHLSASRVERARRTLIEIQESGAKDLATLSVAARQ
MLBr_01249|M.leprae_Br4923          VGEPDESGEEKIAEWEHISASRVERARLMLAEIHASGEKDLATLSVAARQ
Mflv_2569|M.gilvum_PYR-GCK          VGEPDENGVEKIAEWEMTNRSRISRARRTLTELYESGEHDLATLSVAARQ
Mvan_4069|M.vanbaalenii_PYR-1       VGEPDEDGVEKIAEWETTNSSRVSRARRTLAELYESGEHDLATLSVAARQ
MSMEG_4699|M.smegmatis_MC2_155      VGEPDENGEEKIAEWETTNSSRVTRARRTLTEIYKDGEQDLATLSVAARQ
TH_0917|M.thermoresistible__bu      VGEPDESGEEKIAEWESTNSSRLRRARRTLDEIYQDDIRDLATLSVAARQ
MAB_4344c|M.abscessus_ATCC_199      EAAVGGNADRLIAEWERDNWAHVQRAGARLEELAGKASHDVASLSVAARY
                                     .  . .. . * ***  . ::: **   * ::  .  :*:*:****** 

Mb2503c|M.bovis_AF2122/97           IRRMTRTSGRGISG
Rv2476c|M.tuberculosis_H37Rv        IRRMTRTSGRGISG
MMAR_3829|M.marinum_M               VRRMTRTSGRGISG
MAV_1696|M.avium_104                IRRMTRTSGRGSSS
MLBr_01249|M.leprae_Br4923          IRRMTRTSGRGSSG
Mflv_2569|M.gilvum_PYR-GCK          IRSMTRTSGTGSSG
Mvan_4069|M.vanbaalenii_PYR-1       IRSMTRTSGTGSSG
MSMEG_4699|M.smegmatis_MC2_155      IRSMTRTSGTGTTG
TH_0917|M.thermoresistible__bu      IRAMTRTSGTGSSA
MAB_4344c|M.abscessus_ATCC_199      VRSMANLS------
                                    :* *:. *