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TAIQSPVLPYTAHVQEVAERLTGAPQETVRAEFLDDAGDGTIRAVIAWPTEDIALSDICTLFEHFGLRLR RQLPLGPTGAGTYLYEFTSTATPLADSLRNVAAAVQAHGTKHFTVDPFAALILAANIGWRDTVLLRALAR FLKQAGLGMSHAYVIDNLAQRPRFVAALLDYFNARFDPMTADRDRAVTEAARVLDSHVEAATTVDEDRVL RAFATCFGALVRTSWFQVSESGGHKAHQAFMFDSAQLSLCGSVVPYREIFVDCDDMEGLHVRSGAIARGG LRFSDRPEDYRTEVLGLMKTQTVKNSPIVPTGAKGVFIRKNPEITVAQAYSVFINGLLDVTDNIADGKTV HPAHTVTYGADSNYLVVAADKGTAAFSDIANHIAAQRGFWLGDAFAAGGTTGYDHKQMGITARGAWVSVR DHLTEIGIDVDTEAVTVAGIGDCSGDVFGNGMLHSANLRLVAAFDHRHIFIDPDPDPAASHAERRRLHTQ PGSSWADYDPNLISDGGGVWPRSAKNIVLPKPAQELLSVDRQTLTPDQLVQAVLCAKVDLLWNGGIGTYV KSHRESHVDAADPANDSVRVNAEQLRARVIGEGGNLGLTQRARVDFALRGGRVNADFIDNAAGVATSDRE VNLKIALESVCRSGQLTEVQRNARLTAAENDVAATVLSGCHNQVLALGLAEAYAPRLLNRHERLIESLER HNGLNRTAEGLPSESEIAARAQDGRGLTRPEIAVLLAYSKNVVCQELLSSDIPDDPAFVSALSAYFPDSW QCGLLTDGITEHRLAREIIATQISDDLINHVGPGLIYRLEERFGVRSPEVAAAYMVTRRLFKVDSLWEHA RRGGTVGAQGRWQGLHDLQQFIEHTAGRLLRHAGGRIDIAATVERYAAHIDTLRSHLQRNAPDSWLRLRR QAVDLSETAVRLGSDVRNVAQTHLALEEALGMNWVINALESHHPANWWEAMAADALRDDITDALHRLTEF PRHVDGWQPIAPERISRLKEVVARARRDGFVDVPRAAAISAELSSLCRWAGGAGG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_0820c | - | - | 100% (1036) | NAD-glutamate dehydrogenase |
M. abscessus ATCC 19977 | MAB_1561 | - | 0.0 | 39.11% (1038) | NAD-dependent glutamate dehydrogenase |
M. abscessus ATCC 19977 | MAB_4344c | - | e-176 | 39.29% (980) | putative NAD-dependent glutamate dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2503c | gdh | 0.0 | 37.36% (1092) | NAD-dependent glutamate dehydrogenase |
M. gilvum PYR-GCK | Mflv_2569 | - | 0.0 | 38.25% (1038) | NAD-glutamate dehydrogenase |
M. tuberculosis H37Rv | Rv2476c | gdh | 0.0 | 37.36% (1092) | NAD-dependent glutamate dehydrogenase |
M. leprae Br4923 | MLBr_01249 | - | 0.0 | 36.20% (1105) | hypothetical protein MLBr_01249 |
M. marinum M | MMAR_3829 | gdh | 0.0 | 36.78% (1082) | NAD-dependent glutamate dehydrogenase Gdh |
M. avium 104 | MAV_1696 | - | 0.0 | 37.48% (1078) | NAD-glutamate dehydrogenase |
M. smegmatis MC2 155 | MSMEG_4699 | - | 0.0 | 36.90% (1122) | NAD-glutamate dehydrogenase |
M. thermoresistible (build 8) | TH_0917 | - | 1e-173 | 40.58% (892) | PROBABLE NAD-DEPENDENT GLUTAMATE DEHYDROGENASE GDH (NAD-GDH) |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_4069 | - | 0.0 | 37.91% (1100) | NAD-glutamate dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2503c|M.bovis_AF2122/97 ---------------MTIDPGAKQDVEAWTTFTASADIPDWISKAYIDSY Rv2476c|M.tuberculosis_H37Rv ---------------MTIDPGAKQDVEAWTTFTASADIPDWISKAYIDSY MMAR_3829|M.marinum_M ---------------MTIDPGAKQDVGAWTAFTQPADIPDWISQAYLDSY MAV_1696|M.avium_104 MFERIDNRRQLGAIGMTIDPRAQQDLKPWTTFTRQQDIPEWISKAYVESY MLBr_01249|M.leprae_Br4923 ---------------MTIDPGATHVAELCTTFTQGADVPDWISKAYIDSY Mflv_2569|M.gilvum_PYR-GCK ---------------MSLNPGAVN---GATG-AVGAEMVERLIPAYLATY Mvan_4069|M.vanbaalenii_PYR-1 ---------------MSLNPGAIN---GSVGPEVSSEVIDRLLPAYLATY MSMEG_4699|M.smegmatis_MC2_155 -------------------------------------MIRRLSVAFLSTY TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 -RGPRDDS--SEATKAAEASWLPASLLTPAMLGAHYRLGRHRAAGESCVA Rv2476c|M.tuberculosis_H37Rv -RGPRDDS--SEATKAAEASWLPASLLTPAMLGAHYRLGRHRAAGESCVA MMAR_3829|M.marinum_M QRRGEEDS--QASQRAAEA---AASVVTPAMLSAHYRLGQHRPIGESRVA MAV_1696|M.avium_104 RGPHSDES--GGAEAGPIDLTVPTAIVTPAMLSAHYRLGLHRPDGESRVA MLBr_01249|M.leprae_Br4923 RGSHGDVR--EAPETSRVN---PNALVTPAMLSAHYRLGQCRPNGRNCVR Mflv_2569|M.gilvum_PYR-GCK RGPHGGAPGADAAVTGPLRRH-DDGLDTTALVEAQCRLAGTRLPGATNVA Mvan_4069|M.vanbaalenii_PYR-1 RGPHGGAPGAESAVTGPLRRQGTDTVNGPALVAAHYRLGAQRSPGATRVA MSMEG_4699|M.smegmatis_MC2_155 RGPQADAPGVTS--TGPLAVAAHDDLVSDDLVAAHYRLASMRAPGETKAA TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 VYRADDPAGFGPALQVVAEHGGMLMDSVTVLLHRLGIAYAAILTPVFDVH Rv2476c|M.tuberculosis_H37Rv VYRADDPAGFGPALQVVAEHGGMLMDSVTVLLHRLGIAYAAILTPVFDVH MMAR_3829|M.marinum_M VYPADDPVGFGPALQVVTEHGSMLMDSVTVLLHRLGVGYTTIMTPVFEVH MAV_1696|M.avium_104 VYPADDPAGFGPALQVVTDHGGMLMDSVTVLLHRLGVPYTAIMTPVFDVH MLBr_01249|M.leprae_Br4923 VYPADDPAGFGPALQIVTDHGGMVMDSITVLLHRLGVTYTAMMTPVFMVL Mflv_2569|M.gilvum_PYR-GCK VYPGDEATGFGPALQIVTDNASLLMDSVTVLLHRIGVAYTAIMNPGFRVR Mvan_4069|M.vanbaalenii_PYR-1 VHAADVEGGFGPALQVVTDNAAILMDSITVLLHRIGVAYTAIMNPVFRVR MSMEG_4699|M.smegmatis_MC2_155 VYPGDAGS--GAALQIVTDQAPMLVDSVTVLLHRHGIAYTAIMNPVFRVR TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 RSPTGELLRIEPKAEGTSP-----HLGEAWMHVALSPAVDHKGLAEVERL Rv2476c|M.tuberculosis_H37Rv RSPTGELLRIEPKAEGTSP-----HLGEAWMHVALSPAVDHKGLAEVERL MMAR_3829|M.marinum_M RGPTGELQRVEPKSLDASP-----YVGEAWIHVQLSPTVEAKALAEVEQL MAV_1696|M.avium_104 RSPDGDLLSLEPKPQGAPQ-----YAGEAWIHVQLLPSVDSKGLTEAERL MLBr_01249|M.leprae_Br4923 RSPTGELLGVEPRASSTSHSIEGTWVGEVWIYIQLLPAVDSKSLAEVEQL Mflv_2569|M.gilvum_PYR-GCK RGGAGELLDVAPVSDASFSD----GVDETWVHVQLAGSVDRHALAEAEEL Mvan_4069|M.vanbaalenii_PYR-1 RGAGGELQDIAPASDATFVD----GVDETWVHVQLADSVDRRALAEAEEL MSMEG_4699|M.smegmatis_MC2_155 RGLDGELLDVRPAAEAAPGD----GADECWILVPITAAADGEALTEATRL TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 LPKVLADVQRVATDATALIATLSELAGEVESNAGGRFSAPDRQDVGELLR Rv2476c|M.tuberculosis_H37Rv LPKVLADVQRVATDATALIATLSELAGEVESNAGGRFSAPDRQDVGELLR MMAR_3829|M.marinum_M LPKVLADVQRVAKDAPAMIATLSELAVAVDSDREGHYAAPDHQEVAALLR MAV_1696|M.avium_104 LPKVLADVQQVASDASALIAVLDELAAAVEANRDNHFSAPDRDDVAALLR MLBr_01249|M.leprae_Br4923 LPRTLVDVQRVAADAAALNATLSGLAADVKTNKEGHFSASDRDDVAALLH Mflv_2569|M.gilvum_PYR-GCK LPKVLADARQVALDSTDMAAALRILAAELDGDTGRRFPSPDRKDVAALLR Mvan_4069|M.vanbaalenii_PYR-1 LPRVLADARQVALDSTGMAAALRTLAAELDSDPGRRFPSPDRKDVAALLR MSMEG_4699|M.smegmatis_MC2_155 VPGILAEARQIGLDSGAMIAALHGLANDLATDLEGHFPNAERKEVAALLR TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 WLGDGNFLLLGYQRCRVADGMVYGEGSSGMGVLRGRTGSRPRLTDDDKLL Rv2476c|M.tuberculosis_H37Rv WLGDGNFLLLGYQRCRVADGMVYGEGSSGMGVLRGRTGSRPRLTDDDKLL MMAR_3829|M.marinum_M WLGNGNFLLLGYQPCEVDDGMVLGDGSTGLGVLRARTGTRPRLTDETKLL MAV_1696|M.avium_104 WLGNGNFLLLGYQRCRVHDGLVSGDGSPGLGVLRTRTGSRPRLTDDDRLL MLBr_01249|M.leprae_Br4923 WLGNGNFLLLGYQRCRVHYGLVSCDRSTGLGVLRARTGSRPRLTDDNELL Mflv_2569|M.gilvum_PYR-GCK WLADGHFVLLGYQRCPVRDGEATVDTSSRLGVLRLRQDVLPQLTQKDELL Mvan_4069|M.vanbaalenii_PYR-1 WLADGHFVLLGYQRCPVRDGEATVDPSSRLGVLRLREDVFPQLTNKDELL MSMEG_4699|M.smegmatis_MC2_155 WLADGHFVLLGYQQCVVGDGNAEVDPASRLGVLRLRNDVLPPLTDSDDLL TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 VLAQARVGSYLRYGAYPYAIAVREYV------DGSVVEHRFVGLFSVAAM Rv2476c|M.tuberculosis_H37Rv VLAQARVGSYLRYGAYPYAIAVREYV------DGSVVEHRFVGLFSVAAM MMAR_3829|M.marinum_M VLAQARVGSYLRYGAYPYAIAIRESLG-----DGNIVEHRFVGLFTVAAM MAV_1696|M.avium_104 VLAQSVVGSYLRYGAYPYAIAVREYV------DGAVIEHRFVGLFTVAAM MLBr_01249|M.leprae_Br4923 VLAQAAVGNYLRYGAYPYAIAVREYDDG---GDGGIIEHRFVGLFTVAAM Mflv_2569|M.gilvum_PYR-GCK TLAQATIPSFLRYGAYPQIVVVREQSPERDAD---AIEHRFVGLFTVAAM Mvan_4069|M.vanbaalenii_PYR-1 TLAQATIPSFLRYGTYPQIVVVREQSGDADADDAAAIEHRFVGMFTVAAM MSMEG_4699|M.smegmatis_MC2_155 VLAQATMPSYLRYGAYPYIVVVRESPG---ASR--VIEHRFVGLFTVAAM TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 NADVLEIPTISRRVREALAMAESDPSHPGQLLLDVIQTVPRPELFTLSAQ Rv2476c|M.tuberculosis_H37Rv NADVLEIPTISRRVREALAMAESDPSHPGQLLLDVIQTVPRPELFTLSAQ MMAR_3829|M.marinum_M NADVLEIPAISHRVRDALELAGNDPSHPGQLLLDVIQTVPRPELFTLSSE MAV_1696|M.avium_104 NADVLEIPTISRRVREALAMADSDPIHPGQLLLDVIQTVPRSELFTLSSE MLBr_01249|M.leprae_Br4923 NADVLEIPSISHRVRAALAMANSDPIYPGQLLLDVIQTVPRSELFTLSAE Mflv_2569|M.gilvum_PYR-GCK NANVLEIPLVSRRVNDALAMAHRDPSHPGQLLLDIIQTIPRSELFALSAR Mvan_4069|M.vanbaalenii_PYR-1 NANVLEIPLVSRRVNDALAMAHRDPSHPGQLVLDIIQTIPRSELFALSAR MSMEG_4699|M.smegmatis_MC2_155 NANALEIPLISRRVEEALAMAHRDPSHPGQLLRDIIQTIPRPELFALSSK TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 RLLTMARAVVDLGSQRQALLFLRADRLQYFVSCLVYMPRDRYTTAVRMQF Rv2476c|M.tuberculosis_H37Rv RLLTMARAVVDLGSQRQALLFLRADRLQYFVSCLVYMPRDRYTTAVRMQF MMAR_3829|M.marinum_M QLLAMAKAVVDLGSQRRALLFLRVDRLQFFVSCLVYLPRDRYTTAVRLQI MAV_1696|M.avium_104 RLLAMAKAVVDLGPQRNALLFLRADSLQYFVSCLVYLPRDRYTTAVRLQI MLBr_01249|M.leprae_Br4923 RLFTMAKEVVDLGSGRRALLFLRADRLQYFVSCLVYVPRDRYTTGVRLQI Mflv_2569|M.gilvum_PYR-GCK GLLDMAMAVVDLGARRRTLLFMRADPLAHFVSCLVYLPRDRYTTVVRLEM Mvan_4069|M.vanbaalenii_PYR-1 GLLDMAMAVVDLGSRRRALLFMRADPLAHFVSCLVYLPRDRYTTAVRLEM MSMEG_4699|M.smegmatis_MC2_155 QLLEMALAVVDLGSRRRTLLFLRADHLAHFVSCLVYLPRDRYTTAVRLEM TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 EDILVREFGGTRLEFTARVSESPWALMHFMVRLPEVGVAGEGAAAPPVDV Rv2476c|M.tuberculosis_H37Rv EDILVREFGGTRLEFTARVSESPWALMHFMVRLPEVGVAGEGAAAPPVDV MMAR_3829|M.marinum_M EDILVREFGGTRLEFTARVSESPWALMHFMVRLPEDVATGS------IDV MAV_1696|M.avium_104 EDILVREFGGTRLEFTARVSESPWALMHFMVRLPTDDPAAK-----PVDV MLBr_01249|M.leprae_Br4923 EDILVREFGGTQVEFTARVSESPWALMHFMVRLSEGAATGS------VDV Mflv_2569|M.gilvum_PYR-GCK QDILVRELGGVSIDYAARVSESPWAVVHFTVRLPAGLRQHE------VDV Mvan_4069|M.vanbaalenii_PYR-1 QDILVRELGGVSIDYAARVSESPWAVVHFTVRMPEGSRPQD------IDV MSMEG_4699|M.smegmatis_MC2_155 QDILVRELGGAGIDYSARVSESPWAVVHFTVRLPEGTAADS------VDT TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -------------------------------------------------- Mb2503c|M.bovis_AF2122/97 SEANRIRIQGLLTEAARTWADRLIG-AAAAG--SVGQADAMHYAAAFSEA Rv2476c|M.tuberculosis_H37Rv SEANRIRIQGLLTEAARTWADRLIGAAAAAG--SVGQADAMHYAAAFSEA MMAR_3829|M.marinum_M SEANRSRIQALLSEAARTWADRLIG-AASDA--SVRHADAEHYAAAFPEA MAV_1696|M.avium_104 SEDNRVRIQGLLSEAARTWTDRLVA-AAAEG--AVGHADAEYYADAFPEV MLBr_01249|M.leprae_Br4923 SEGNRIRIQAMLSEAARTWSDRLIAAAASFSEGSVSYAEAEHYAATFSET Mflv_2569|M.gilvum_PYR-GCK SDDNEARIQDLLTEAARTWGDRLMGALPAGG--PVDHGTADHYASAFPEV Mvan_4069|M.vanbaalenii_PYR-1 SEPNESRIQDLLTEAARTWSDRLLGAVSAGG--EVDQATAEHYASAFSEV MSMEG_4699|M.smegmatis_MC2_155 SLENESRIQDLLTEATRNWGDRMISAAAAA---SISPAALEHYAHAFPED TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 --------------------------------MTAIQSPVLPYTAHVQEV Mb2503c|M.bovis_AF2122/97 YKQAVTPADAIGDIAVITELTDDSVKLVFSER---DEQGVAQLTWFLGGR Rv2476c|M.tuberculosis_H37Rv YKQAVTPADAIGDIAVITELTDDSVKLVFSER---DEQGVAQLTWFLGGR MMAR_3829|M.marinum_M YKQAVAPADAIDHIAIINELADDSVKLVFSDR---TADGVAQLTWFLGGC MAV_1696|M.avium_104 YKQAISPADAIGHIAIIKELQDNSVKLVFTD----GEDGSAQLTWFLGGR MLBr_01249|M.leprae_Br4923 YKQAVTPADAIDHIAIIKELADDSVKLVFFER---KADGFAQLTWFLGGR Mflv_2569|M.gilvum_PYR-GCK YKQANTPARALDDIAIIEELHDNTVKLVLADSDDTETSGVSDLNWYLGGQ Mvan_4069|M.vanbaalenii_PYR-1 YKQAIDPVHALADIAVIEELQDNSVKLVLADSDDTAESGVSHLNWYLGGR MSMEG_4699|M.smegmatis_MC2_155 YKQAFAPQDAIADISLIEALQDDSVKLVLAD---TAEDRVWKLTWYLGGH TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 AERLTGAPQETVRAEFLDDAGDGTIRAVIAWP----------------TE Mb2503c|M.bovis_AF2122/97 TASLSQLLPMLQSMGVVVLEERPFSVTRPDGLPVWIYQFKISPHPTIPLA Rv2476c|M.tuberculosis_H37Rv TASLSQLLPMLQSMGVVVLEERPFSVTRPDGLPVWIYQFKISPHPTIPLA MMAR_3829|M.marinum_M TASLSQLLPMLQSMGVVVLEERPFTVTRPDGLPVWIYQFKISPHPTIPKA MAV_1696|M.avium_104 TASLSQLLPMLQSMGVVVLEERPFTVTRSDGLPVWIYQFRISPHPTIELA MLBr_01249|M.leprae_Br4923 SASLSQLLPMLQSMGVVVLEERPFTVARTDGLPVWIYQFKISPHPTIPLA Mflv_2569|M.gilvum_PYR-GCK SASLSRLLPMLQSMGVVVLEERPFTVTRPDGLPVWIYQFKVSPHRGIPQA Mvan_4069|M.vanbaalenii_PYR-1 SASLSRLLPMLQSMGVVVLEERPFTVVRPDGLPVWIYQFKVSPHRGIPEA MSMEG_4699|M.smegmatis_MC2_155 SASLSELLPMLQSMGVVVLEERPFTLRRTDGLPVWIYQFKISPHPSIPHA TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 DIALSDICTLFEHFGLRLRRQLPLG---PTGAGTYLYEFTSTATP----- Mb2503c|M.bovis_AF2122/97 PTVAERAATAHRFAEAVTAIWHGRVEIDRFNELVMRAGLTWQQVVLLRAY Rv2476c|M.tuberculosis_H37Rv PTVAERAATAHRFAEAVTAIWHGRVEIDRFNELVMRAGLTWQQVVLLRAY MMAR_3829|M.marinum_M TVPAERAAAAQRFADAVTAIWQGRIEIDRFNELVMRAGLTWQQVVLLRAY MAV_1696|M.avium_104 STPDERDAMAERFADAVTAIWQGRLEVDRFNELVMRAGLRWQQVVLLRAY MLBr_01249|M.leprae_Br4923 STANERELTAKRFSDAVTAIWQGRVEIDRFNELVMRARLTWQQVVLLRAY Mflv_2569|M.gilvum_PYR-GCK PPGPERDATAERFADTVTAIWHGNAEIDRFNELVLRAGLTWQQVAVLRAY Mvan_4069|M.vanbaalenii_PYR-1 PPGPQREATAERFADAVTAIWHGNAEIDRFNELVLRAELTWQQVAVLRAY MSMEG_4699|M.smegmatis_MC2_155 PDAEAQRDTAQRFADAVTAIWHGRVEIDRFNELVMRAGLTWQQVVVLRAY TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 -----LADSLRNVAAAVQAHGTKHFTVDPFAALILAANIGWRDTVLLRAL Mb2503c|M.bovis_AF2122/97 AKYLRQAGFPYSQSYIESVLNEHPATVRSLVDLFEALFVP-VPSGSASNR Rv2476c|M.tuberculosis_H37Rv AKYLRQAGFPYSQSYIESVLNEHPATVRSLVDLFEALFVP-VPSGSASNR MMAR_3829|M.marinum_M SRYLRQAGFPYSQSYIESVLNEHPSTARSLVLLFEALFDP-RPAGSPVSP MAV_1696|M.avium_104 AKYLRQANFPYSQSYIEAVLNEHPSTARSLVALFEALFDP-DPD-SSAGR MLBr_01249|M.leprae_Br4923 AKYLRQAGFNYSQSYIESVLNEHPSTARSLVALFEALFDP-SPLSSSTNC Mflv_2569|M.gilvum_PYR-GCK AKYLKQAGFPYSQSHIASVLNDNAGTARSLVELFEALYSPVDGNPGGANR Mvan_4069|M.vanbaalenii_PYR-1 ARYLKQAGFAYSQSHIESVLNDNAGTARSLIALFEALFRPVEQGPG-ANR MSMEG_4699|M.smegmatis_MC2_155 AKYLRQAGFPYSQSHIESVLNENPHTTRSLIDLFEALFDPSQETDG--RR TH_0917|M.thermoresistible__bu -------------------------------------------------- MAB_0820c|M.abscessus_ATCC_199 ARFLKQAGLGMSHAYVIDNLAQRPRFVAALLDYFNARFDP---MTADRDR Mb2503c|M.bovis_AF2122/97 DAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTRQGSARC Rv2476c|M.tuberculosis_H37Rv DAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTRQGSARC MMAR_3829|M.marinum_M DAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVSREGSARS MAV_1696|M.avium_104 DAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTREGSARA MLBr_01249|M.leprae_Br4923 DAQAAAAAVAADIDALVSLDTDRILRAFASLVQATLRTNYFVTQKFSARS Mflv_2569|M.gilvum_PYR-GCK DAQSAAAAVAADIDALVSLDTDRVLRAFASMIQATLRTNYFVTAADSARA Mvan_4069|M.vanbaalenii_PYR-1 DAQAAAAAVAADIDALVSLDTDRVLRAFASMIQATLRTNYFITGQESARA MSMEG_4699|M.smegmatis_MC2_155 DAQGAAAAVAADIDALVSLDTDRVLRAFANLIEATLRTNYFVARPDSARA TH_0917|M.thermoresistible__bu ---------------VVSLDTDRVLRAFASLIEATLRTNYFVSRDDSDRA MAB_0820c|M.abscessus_ATCC_199 AVTEAARVLDSHVEAATTVDEDRVLRAFATCFGALVRTSWFQVSE-SGGH .::* **:*****. . * :**.:* * Mb2503c|M.bovis_AF2122/97 RDVLALKLNAQLIDELPLPRPRYEIFVYSPRVEGVHLRFGPVARGGLRWS Rv2476c|M.tuberculosis_H37Rv RDVLALKLNAQLIDELPLPRPRYEIFVYSPRVEGVHLRFGPVARGGLRWS MMAR_3829|M.marinum_M RDVLSVKLDAQLIDELPLPRPKYEIFVYSPRVEGVHLRFGPVARGGLRWS MAV_1696|M.avium_104 RNVLVIKLDAQLIDELPLPRPKYEIFVYSPRVEGVHLRFGPVARGGLRWS MLBr_01249|M.leprae_Br4923 KGVLVLKLDAQLINELPLPRPKFEIFVYSPRVEGVHLRFGAVARGGLRWS Mflv_2569|M.gilvum_PYR-GCK RNVLSFKLNPELIDELPLPRPKFEIFVYSPRVEGVHLRFGFVARGGLRWS Mvan_4069|M.vanbaalenii_PYR-1 RNVLSLKLNPQLIDELPLPRPKFEIFVYSPRVEGVHLRFGFVARGGLRWS MSMEG_4699|M.smegmatis_MC2_155 RNVLAFKLNPLVIKELPLPRPKFEIFVYSPRVEGVHLRFGFVARGGLRWS TH_0917|M.thermoresistible__bu RGVFSVKLRPALIKELPLPRPMFEIFVYSPRVEGVHLRFGHVARGGLRWS MAB_0820c|M.abscessus_ATCC_199 KAHQAFMFDSAQLSLCGSVVPYREIFVDCDDMEGLHVRSGAIARGGLRFS : . : . :. * **** . :**:*:* * :******:* Mb2503c|M.bovis_AF2122/97 DRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLPTGDPAADRD Rv2476c|M.tuberculosis_H37Rv DRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLPTGDPAADRD MMAR_3829|M.marinum_M DRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLSTGDAATDRE MAV_1696|M.avium_104 DRRDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPLPSGDGAADRD MLBr_01249|M.leprae_Br4923 DRLDDFRTEILGLVKAQAVKNAVIVPVGAKGGFVLKRPPLPTGDAAADRD Mflv_2569|M.gilvum_PYR-GCK DRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKKPPAPTGDAAADRD Mvan_4069|M.vanbaalenii_PYR-1 DRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKHPPAPTGDAAADRD MSMEG_4699|M.smegmatis_MC2_155 DRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPTLTGDAAADRE TH_0917|M.thermoresistible__bu DRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPAPTGDAAADRE MAB_0820c|M.abscessus_ATCC_199 DRPEDYRTEVLGLMKTQTVKNSPIVPTGAKGVFIRKNPEITVAQ------ ** :*:***:***:*:*:***: ***.**** *: *.* .: Mb2503c|M.bovis_AF2122/97 ATRAEGVACYQLFISGLLDVTDNVDHATASVNPPPEVVRRDGDDAYLVVA Rv2476c|M.tuberculosis_H37Rv ATRAEGVACYQLFISGLLDVTDNVDHATASVNPPPEVVRRDGDDAYLVVA MMAR_3829|M.marinum_M ATRAEGVACYQLFISGLLDVTDNVDHTTGVVSPPPEVLRRDGDDAYLVVA MAV_1696|M.avium_104 ATRAEGVACYQLFISGLLDVTDNVDHATGKVSPPPEVVRRDGDDAYLVVA MLBr_01249|M.leprae_Br4923 AMRAEGIACYQLFISGLLDITDNVDHATGKVNAPPQVVRRDSDDAYLVVA Mflv_2569|M.gilvum_PYR-GCK ATREEGVACYRLFIAGLLDITDNVDKISGDVVTPAEVVRRDGDDAYLVVA Mvan_4069|M.vanbaalenii_PYR-1 ATREEGVACYRLFIAGLLDITDNVDKVTGGIVAPADVVRRDGDDAYLVVA MSMEG_4699|M.smegmatis_MC2_155 ATRAEGVECYRLFISGLLDVTDNVDKATGAVVTPPEVVRRDGEDAYLVVA TH_0917|M.thermoresistible__bu AARAEGIACYRLFVSGLLDITDNVDKTTGAVVPPAEVVRRDGDDAYLVVA MAB_0820c|M.abscessus_ATCC_199 --------AYSVFINGLLDVTDNI--ADGKTVHPAHTVTYGADSNYLVVA .* :*: ****:***: . *...: ..:. ***** Mb2503c|M.bovis_AF2122/97 ADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITARGAWEA Rv2476c|M.tuberculosis_H37Rv ADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITARGAWEA MMAR_3829|M.marinum_M ADKGTATFSDIANEVANSYGFWLGDAFASGGSVGYDHKAMGITAKGAWEA MAV_1696|M.avium_104 ADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITARGAWEA MLBr_01249|M.leprae_Br4923 ADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGAWEA Mflv_2569|M.gilvum_PYR-GCK ADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGAWES Mvan_4069|M.vanbaalenii_PYR-1 ADKGTATFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGAWES MSMEG_4699|M.smegmatis_MC2_155 ADKGTATFSDIANEVAKSYGFWLGDAFASGGSIGYDHKAMGITAKGAWES TH_0917|M.thermoresistible__bu ADKGTATFSDIANEVAQSYGFWLGDAFASGGSVGYDHKAMGITARGAWES MAB_0820c|M.abscessus_ATCC_199 ADKGTAAFSDIANHIAAQRGFWLGDAFAAGGTTGYDHKQMGITARGAWVS ******:******.:* . *********:**: ***** *****:*** : Mb2503c|M.bovis_AF2122/97 VKRHFREIGIDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFDHRH Rv2476c|M.tuberculosis_H37Rv VKRHFREIGIDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFDHRH MMAR_3829|M.marinum_M VKRHFREMGIDTQTEDFTVVGVGDMSGDVFGNGMLLSKHIRLIAAFDHRH MAV_1696|M.avium_104 VKRHFREMGVDTQTEDFTVVGIGDMSGDVFGNGMLLSKHIRLLAAFDHRH MLBr_01249|M.leprae_Br4923 VKRHFREMGVDTQNEDFTVVGIGDMSGDVFGNGMLLSKHIRLIAAFDHRH Mflv_2569|M.gilvum_PYR-GCK VKRHFREMGIDTQSEDFTVVGVGDMSGDVFGNGMLLSEHIRLLAAFDHRH Mvan_4069|M.vanbaalenii_PYR-1 VKRHFREMGVDTQSEDFTVVGVGDMSGDVFGNGMLLSKHIRLLAAFDHRH MSMEG_4699|M.smegmatis_MC2_155 VKRHFREMGVDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLVAAFDHRD TH_0917|M.thermoresistible__bu VKRHFREMGVDTQTQDFTVVGIGDMSGDVFGNGMLLSKHIRLVAAFDHRH MAB_0820c|M.abscessus_ATCC_199 VRDHLTEIGIDVDTEAVTVAGIGDCSGDVFGNGMLHSANLRLVAAFDHRH *: *: *:*:*.:.: .**.*:** ********** * ::**:******. Mb2503c|M.bovis_AF2122/97 IFLDPNPDAAVSWAERRRMFELPRSSWGDYDRSLISEGGGVYSREQKAIP Rv2476c|M.tuberculosis_H37Rv IFLDPNPDAAVSWAERRRMFELPRSSWSDYDRSLISEGGGVYSREQKAIP MMAR_3829|M.marinum_M VFLDPNPDAAASWQERQRMFDLPRSSWDDYNKSLISEGGGVYSREQKSIP MAV_1696|M.avium_104 IFLDPNPDAAASWEERRRMFELPRSSWDDYDKSLISEGGGVYSREHKSIP MLBr_01249|M.leprae_Br4923 VFLDPDPDAAVSWAERQRMFDLPRSSWDDYNKSLISEGGGVYSREQKAIP Mflv_2569|M.gilvum_PYR-GCK IFIDPTPDAASSYAERRRLFDLPRSSWDDYDKSLISAGGGVYSREQKSIP Mvan_4069|M.vanbaalenii_PYR-1 IFIDPTPDAASSWEERKRLFELPRSSWEDYDTSLISPGGGVYSREQKSIP MSMEG_4699|M.smegmatis_MC2_155 IFLDPNPDAGRSWDERKRLFDLPRSSWADYDKSLISEGGGVYSRQQKSIP TH_0917|M.thermoresistible__bu IFLDPDPDPARSWEERKRLFELPRSSWDDYDTSVISRGGGVYSRQQKSIP MAB_0820c|M.abscessus_ATCC_199 IFIDPDPDPAASHAERRRLHTQPGSSWADYDPNLISDGGGVWPRSAKNIV :*:** **.. * **:*:. * *** **: .:** ****:.*. * * Mb2503c|M.bovis_AF2122/97 LSAQVRAVLGIDGSVDGGAAEMAPPNLIRAILRAPVDLLFNGGIGTYIKA Rv2476c|M.tuberculosis_H37Rv LSAQVRAVLGIDGSVDGGAAEMAPPNLIRAILRAPVDLLFNGGIGTYIKA MMAR_3829|M.marinum_M VSDQVRNALGIGGDVT----EMTPPNLIRAILQAPVDLLFNGGIGTYIKA MAV_1696|M.avium_104 VSPQVRDALGLDGSGGGVVTEMTPPNLIKAILQAPVDLLFNGGIGTYIKA MLBr_01249|M.leprae_Br4923 TSPQVRTALGIDGEVT----EMAPPNLIRAILQAPVDLLFNGGIGTYIKA Mflv_2569|M.gilvum_PYR-GCK ISDEARAALGIEGDAT----EMTPPALMKAILKAPADLLWNGGIGTYIKA Mvan_4069|M.vanbaalenii_PYR-1 VSAQARAALGLDDQVT----DLTPPALMKAILKAPADLLWNGGIGTYVKA MSMEG_4699|M.smegmatis_MC2_155 ISPQVRTALGLDADVE----ELTPPALIKAILKAPVDLLWNGGIGTYIKA TH_0917|M.thermoresistible__bu VSAEVRAALGLDGDVD----ALTPPAMIRAILRAPVDLLFNGGIGTYIKA MAB_0820c|M.abscessus_ATCC_199 LPKPAQELLSVDRQTL------TPDQLVQAVLCAKVDLLWNGGIGTYVKS . .: *.: . :* :::*:* * .***:*******:*: Mb2503c|M.bovis_AF2122/97 ESESDADVGDRANDPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLSGGR Rv2476c|M.tuberculosis_H37Rv ESESDADVGDRANDPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLSGGR MMAR_3829|M.marinum_M ESESDADVGDRANNPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLSGGR MAV_1696|M.avium_104 ESESDADVGDRANDPVRVNGSSVRAKVIGEGGNLGVTALGRVEFDLSGGR MLBr_01249|M.leprae_Br4923 ETESVADVGDRANDPVRVNANQVRAKVIGEGGNLGVTALGRVEFDLSGGR Mflv_2569|M.gilvum_PYR-GCK ETEADADVGDRANDPVRVNGNQVRAKVVGEGGNLGVTSLGRTEFDLCGGR Mvan_4069|M.vanbaalenii_PYR-1 ETEADADVGDRANDAVRVNGNEVRAKVIGEGGNLGVTSRGRTEFDLCGGR MSMEG_4699|M.smegmatis_MC2_155 ETEADADVGDRANDQIRVCGNQVRAKVIGEGGNLGVTALGRIEFDLAGGR TH_0917|M.thermoresistible__bu ESESDADVGDRANDPVRVNGNQVRAKVIGEGGNLGVTPLGRVEYDLAGGR MAB_0820c|M.abscessus_ATCC_199 HRESHVDAADPANDSVRVNAEQLRARVIGEGGNLGLTQRARVDFALRGGR . *: .*..* **: :** ...:**:*:*******:* .* :: * *** Mb2503c|M.bovis_AF2122/97 INTDALDNSAGVDCSDHEVNIKILIDSLVSAGTVKADERTQLLESMTDEV Rv2476c|M.tuberculosis_H37Rv INTDALDNSAGVDCSDHEVNIKILIDSLVSAGTVKADERTQLLESMTDEV MMAR_3829|M.marinum_M INTDALDNSAGVDCSDHEVNIKILIDSLVSAGKVRTDERKQLLESMTDEV MAV_1696|M.avium_104 INTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVKPQERKPLLESMTDEV MLBr_01249|M.leprae_Br4923 INTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVKVEERKHLLESMTDEV Mflv_2569|M.gilvum_PYR-GCK INTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVAEADRTELLLSMTDEV Mvan_4069|M.vanbaalenii_PYR-1 INTDAMDNSAGVDCSDHEVNIKILIDSLVTAGKVEESGRSALLSSMTDEV MSMEG_4699|M.smegmatis_MC2_155 INTDALDNSAGVDCSDHEVNIKILIDSAVTAGKVTPEERTELLLSMTDEV TH_0917|M.thermoresistible__bu INTDALDNSAGVDCSDHEVNIKILIDSLVAAGKIGADQRTDLLMSMTDEV MAB_0820c|M.abscessus_ATCC_199 VNADFIDNAAGVATSDREVNLKIALESVCRSGQLTEVQRNARLTAAENDV :*:* :**:*** **:***:** ::* :* : *. * : ::* Mb2503c|M.bovis_AF2122/97 AQLVLADNEDQNDLMGTSRANAASLLPVHAMQIKYLVAERGVNRELEALP Rv2476c|M.tuberculosis_H37Rv AQLVLADNEDQNDLMGTSRANAASLLPVHAMQIKYLVAERGVNRELEALP MMAR_3829|M.marinum_M AQLVLTDNSDQNDLMGTSRANPVSLLPVHADQIRYLVAERGISRELEALP MAV_1696|M.avium_104 AALVLTDNEDQNDLIGTSRANAPSLLPVHARQIQYLVDERGLNRELEALP MLBr_01249|M.leprae_Br4923 ARLVLTDNEDQNDLIGTSRANAANMLSVHAMQIKYLVDERGVNRELEALP Mflv_2569|M.gilvum_PYR-GCK GRLVLADNESQNDLMGTSRANAASLLNVHARMIKDFVERRGLNRELEALP Mvan_4069|M.vanbaalenii_PYR-1 GRLVLADNESQNDLMGTSRANAASLLNVHGRMIRSFVEERGLNRELEALP MSMEG_4699|M.smegmatis_MC2_155 GELVLADNRDQNDLMGTSRANAASLLSVHARMIKDLVDNRGLNRELEALP TH_0917|M.thermoresistible__bu ADMVLAHNARQNDLIGTSRANTAAMLTVHARLIDDLVENHGVNRELEALP MAB_0820c|M.abscessus_ATCC_199 AATVLSGCHNQVLALGLAEAYAPRLLNRHERLIESLERHNGLNRTAEGLP . **: * :* :.* . :* * * : ..*:.* *.** Mb2503c|M.bovis_AF2122/97 SEKEIARRSEAGIGLTSPELATLMAHVKLGLKEEVLATELPDQDVFASRL Rv2476c|M.tuberculosis_H37Rv SEKEIARRSEAGIGLTSPELATLMAHVKLGLKEEVLATELPDQDVFASRL MMAR_3829|M.marinum_M SEKEIARRSEAGIGLTSPELATLMAHVKLALKETMLTTELPDQDVFASRL MAV_1696|M.avium_104 SEKEIQRRAEAGIGLTSPELCTLMAHVKLDLKEQMLQTELTEQDVFASRL MLBr_01249|M.leprae_Br4923 SEKEIQRRSEAGIGLTSPELSTLMAHVKLALKEQMLATELPDQDVFVSRL Mflv_2569|M.gilvum_PYR-GCK SEKEILRRTEAGLGLTSPELATLMAHVKLALKDDLLAGELPDQEVFASRL Mvan_4069|M.vanbaalenii_PYR-1 SEKEIRRREEAGIGLTSPELATLMAHVKLALKDDLLAGDLPDQEVFASRL MSMEG_4699|M.smegmatis_MC2_155 SEKEIRRRADAGIGLTSPELATLMAHVKLALKDDVLASDLPDQEVFASRL TH_0917|M.thermoresistible__bu SDKEIARRSDTGVGLTSPELATVMAHVKLTLKDALLASELPDQEVFAARL MAB_0820c|M.abscessus_ATCC_199 SESEIAARAQDGRGLTRPEIAVLLAYSKNVVCQELLSSDIPDDPAFVSAL *:.** * : * *** **:..::*: * : : :* ::.:: .*.: * Mb2503c|M.bovis_AF2122/97 PRYFP-TALRERFTPEIRSHQLRREIVTTMLINDLVDTAGITYAFRIAED Rv2476c|M.tuberculosis_H37Rv PRYFP-TALRERFTPEIRSHQLRREIVTTMLINDLVDTAGITYAFRIAED MMAR_3829|M.marinum_M PSYFP-KPLRERFAPEIRSHQLRREIVTTMVINDLVDTAGITYAFRITED MAV_1696|M.avium_104 PLYFP-TPLRHRFTPEIRAHQLRREIVATMLINELVDAAGISYAFRIVED MLBr_01249|M.leprae_Br4923 PRYFP-KPLRERFTPEIRSHQLRREIVTTMLINDLVDTAGISYAFRIAED Mflv_2569|M.gilvum_PYR-GCK PSYFP-TTLRERFGPDIRSHQLRREIVTTMLVNDVVDTAGISYAYRVAED Mvan_4069|M.vanbaalenii_PYR-1 PSYFP-ATLRDQFSPEIRAHQLRREIVTTMLVNDVVDTAGISYAYRVTED MSMEG_4699|M.smegmatis_MC2_155 PYYFP-TRLREELHGEIRSHQLRREIITTMLVNDLVDTAGISYAYRITED TH_0917|M.thermoresistible__bu PSYFP-RPLRD-FTAEIRGHQLRREIVSTMLVNDLVDTAGLTYAFRVCED MAB_0820c|M.abscessus_ATCC_199 SAYFPDSWQCGLLTDGITEHRLAREIIATQISDDLINHVGPGLIYRLEER . *** : * *:* ***::* : ::::: .* :*: * Mb2503c|M.bovis_AF2122/97 VGVTPIDAVRTYVATDAIFGVGHIWRRIRAAN----LPIALSDRLT--LD Rv2476c|M.tuberculosis_H37Rv VGVTPIDAVRTYVATDAIFGVGHIWRRIRAAN----LPIALSDRLT--LD MMAR_3829|M.marinum_M VGVSPIDAVRTYMATDAIFGVSHIWRRIRAEE----LPVALSDRLT--LD MAV_1696|M.avium_104 VGVSAVDAVRTYVATDAIFGVGEIWRRIRAAN----LPVALSDRLT--LD MLBr_01249|M.leprae_Br4923 IGVGPIDAIRTYVATDAIFGVGDVLRRIRAAN----LSVVLSDRMT--LD Mflv_2569|M.gilvum_PYR-GCK VGVAPIDAVRSFAAGDAIFGFGRVWRQIREAGANGVS-VAVTDRMT--LD Mvan_4069|M.vanbaalenii_PYR-1 VGVAPVDAVRSFVAADAIFGVGRVWRQIREAGANGVP-VAVTDRMT--LD MSMEG_4699|M.smegmatis_MC2_155 VGVGPVDAVRSYVAINAIFGIGDVWRRIRAAGDAGVP-TSVTDRMT--LD TH_0917|M.thermoresistible__bu AGVEPVDAVRSFVAVDAIFRVGEIWHAIRTAGAEGVLPVAVSDRMT--LD MAB_0820c|M.abscessus_ATCC_199 FGVRSPEVAAAYMVTRRLFKVDSLWEHARRGG-----TVGAQGRWQGLHD ** . :. :: . :* .. : . * .* * Mb2503c|M.bovis_AF2122/97 TRRLIDRAGRWLLNYRPQPLAVGAEINRFAAMVKALTPRMSEWLRGDDKA Rv2476c|M.tuberculosis_H37Rv TRRLIDRAGRWLLNYRPQPLAVGAEINRFAAMVKALTPRMSEWLRGDDKA MMAR_3829|M.marinum_M TRRLIDRASRWLLNYRPQPLAVGAEINRFAAKVKALTPRMSEWLRGDDKA MAV_1696|M.avium_104 TRRLIDRAGRWLLNYRPQPLAVGAEINRFAAKVKALTPRMSEWLRGDDKA MLBr_01249|M.leprae_Br4923 TRRLIDRAGRWLLNYRPQPLAVGAEINRFAAKVKALTPRMSEWLRGDDQA Mflv_2569|M.gilvum_PYR-GCK LRRLIDRATRWLLNYRPLPLAVGAEINRFADKVAALTPSMPDWLRGDDKA Mvan_4069|M.vanbaalenii_PYR-1 LRRLIDRAARWLLNYRPQPLAVGAEINRFADKVAALTPRMPDWLRGDDKA MSMEG_4699|M.smegmatis_MC2_155 LRRLVDRAGRWLLNYRPQPLAVGAEINRFGAKVAALTPRMSEWLRGDDKA TH_0917|M.thermoresistible__bu LRRLIDRAARWLLNFRPQPLAVGAEINRFAAKVAALTPRMSEWLCGADAD MAB_0820c|M.abscessus_ATCC_199 LQQFIEHTAGRLLRHAGGRIDIAATVERYAAHIDTLR------------S ::::::: **.. : :.* ::*:. : :* Mb2503c|M.bovis_AF2122/97 IVEKTAAEFASQGVPEDLAYRVSTGLYRYSLLDIIDIADIADIDAAEVAD Rv2476c|M.tuberculosis_H37Rv IVEKTAAEFASQGVPEDLAYRVSTGLYRYSLLDIIDIADIADIDAAEVAD MMAR_3829|M.marinum_M IVEKTSEEFIAQGAPEDLAYRVAVGLYRYSLLDIIDIADIADIDAAEVAD MAV_1696|M.avium_104 IVEKEAAEFESQGAPRDLAYLVAAGLYRFSLLDIIDIGDINDIDAAEVAD MLBr_01249|M.leprae_Br4923 IVEQQATEFVSQGAPEDLAYRVAVGLYRYSLLDIIDIADITELDPAEVAD Mflv_2569|M.gilvum_PYR-GCK IVEKEAGEFSAHGVAEDVAYTVATGLYQFSLLDVIDIADIIDRDPAEVAD Mvan_4069|M.vanbaalenii_PYR-1 IVAKEAAEFSSQGVPDDVAYMVASGLYQFSLLDVIDIADIVDRDPAEVAD MSMEG_4699|M.smegmatis_MC2_155 IVSKEAGDFASHGVPEDLAYHIATGLYQYSLLDVIDIADIVDREPDEVAD TH_0917|M.thermoresistible__bu IVARRTADFVEHGASRQLAYLVSSALYQFSLLDIIDIADILDREPAEVAE MAB_0820c|M.abscessus_ATCC_199 HLQRNAPDSWLR--------------LRRQAVDLSETAVRLGSDVRNVAQ : : : : : : . :*: : . : :**: Mb2503c|M.bovis_AF2122/97 TYFALMDRLGTDGLLTAVSQLPRHDRWHSLARLAIRDDIYGALRSLCFDV Rv2476c|M.tuberculosis_H37Rv TYFALMDRLGTDGLLTAVSQLPRHDRWHSLARLAIRDDIYGALRSLCFDV MMAR_3829|M.marinum_M TYFALVDRLGADGLLTAVSELPRKDRWHSLARLAIRDDIYGALRSLCFDV MAV_1696|M.avium_104 TYFALMDRLGTDGLLTAVSELPRNDRWHSLARLAICDDIYASLRSLCFDV MLBr_01249|M.leprae_Br4923 TYFSLMDRLGTDGLLTAVSKLPQNDRWHSLARLAIRDDIYASLRSLCFDV Mflv_2569|M.gilvum_PYR-GCK AYFALMDHLGTDGLLTAVSRLSRNDRWHSLARLAIRDDIYGSLRALCFDV Mvan_4069|M.vanbaalenii_PYR-1 AYFALMDHLGTDGLLTAVSRLSRYDRWHSLARLAIRDDIYGSLRALCFDV MSMEG_4699|M.smegmatis_MC2_155 TYFALMDHLGADALLTAVSRLSRDDRWHSLARLAIRDDIYGSLRALCFDV TH_0917|M.thermoresistible__bu TYFALMGHLNADALLTAVSELPRSDRWHSLARLAIRDDIYGSLRLLTVDV MAB_0820c|M.abscessus_ATCC_199 THLALEEALGMNWVINALESHHPANWWEAMAADALRDDITDALHRLTEFP ::::* *. : ::.*:. : *.::* *: *** :*: * Mb2503c|M.bovis_AF2122/97 LAVGEPGESSEQKIAEWEHLSASRVARARRTLDDIRASGQKDLATLSVAA Rv2476c|M.tuberculosis_H37Rv LAVGEPGESSEQKIAEWEHLSASRVARARRTLDDIRASGQKDLATLSVAA MMAR_3829|M.marinum_M IAVGEPDESSEQKILEWEQLSASRVDRARRTLNEIRDSGQKDLATLSVAA MAV_1696|M.avium_104 LAVGEPDESGEEKIAEWEHLSASRVERARRTLIEIQESGAKDLATLSVAA MLBr_01249|M.leprae_Br4923 LAVGEPDESGEEKIAEWEHISASRVERARLMLAEIHASGEKDLATLSVAA Mflv_2569|M.gilvum_PYR-GCK LAVGEPDENGVEKIAEWEMTNRSRISRARRTLTELYESGEHDLATLSVAA Mvan_4069|M.vanbaalenii_PYR-1 LAVGEPDEDGVEKIAEWETTNSSRVSRARRTLAELYESGEHDLATLSVAA MSMEG_4699|M.smegmatis_MC2_155 LAVGEPDENGEEKIAEWETTNSSRVTRARRTLTEIYKDGEQDLATLSVAA TH_0917|M.thermoresistible__bu LAVGEPDESGEEKIAEWESTNSSRLRRARRTLDEIYQDDIRDLATLSVAA MAB_0820c|M.abscessus_ATCC_199 RHVDG-----------WQPIAPERISRLKEVVARARRDGFVDVPRAAAIS *. *: .*: * : : .. *:. :. : Mb2503c|M.bovis_AF2122/97 RQIRRMTRTSGRGISG Rv2476c|M.tuberculosis_H37Rv RQIRRMTRTSGRGISG MMAR_3829|M.marinum_M RQVRRMTRTSGRGISG MAV_1696|M.avium_104 RQIRRMTRTSGRGSSS MLBr_01249|M.leprae_Br4923 RQIRRMTRTSGRGSSG Mflv_2569|M.gilvum_PYR-GCK RQIRSMTRTSGTGSSG Mvan_4069|M.vanbaalenii_PYR-1 RQIRSMTRTSGTGSSG MSMEG_4699|M.smegmatis_MC2_155 RQIRSMTRTSGTGTTG TH_0917|M.thermoresistible__bu RQIRAMTRTSGTGSSA MAB_0820c|M.abscessus_ATCC_199 AELSSLCRWAG-GAGG :: : * :* * .