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VSTEELPDIAGIAHHPDGHPRGAVVLTHGAGGSCHSPMLRLLCTAWAERGWLAIRFDMPFRRNRPSGPPS ASSADKDRAGIAEVINKARAMVDGPLLAGGHSYGGRQTSMLVAEKGPIVDVLTLFSYPLHPPGKPDRLRI EHLPDIQVPTVFTHGTSDAFGTIAELKEASVLIPGGAAIVEIAGARHDLGSKTIDVPALAIDAALTALKS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4198 | - | - | 100% (210) | hypothetical protein MAB_4198 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0429c | - | 4e-73 | 62.50% (200) | hypothetical protein Mb0429c |
| M. gilvum PYR-GCK | Mflv_0182 | - | 7e-76 | 66.18% (207) | hypothetical protein Mflv_0182 |
| M. tuberculosis H37Rv | Rv0421c | - | 4e-73 | 62.50% (200) | hypothetical protein Rv0421c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0733 | - | 2e-71 | 63.29% (207) | hypothetical protein MMAR_0733 |
| M. avium 104 | MAV_4733 | - | 5e-76 | 67.00% (203) | hypothetical protein MAV_4733 |
| M. smegmatis MC2 155 | MSMEG_0824 | - | 1e-70 | 62.93% (205) | hypothetical protein MSMEG_0824 |
| M. thermoresistible (build 8) | TH_1511 | - | 7e-68 | 59.31% (204) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3276 | - | 1e-05 | 27.42% (186) | hypothetical protein MUL_3276 |
| M. vanbaalenii PYR-1 | Mvan_0723 | - | 7e-75 | 66.01% (203) | hypothetical protein Mvan_0723 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0824|M.smegmatis_MC2_155 ------------------------------------------MARDARQT
TH_1511|M.thermoresistible__bu ------------------------------------------MS------
Mb0429c|M.bovis_AF2122/97 ------------------------------------------MN------
Rv0421c|M.tuberculosis_H37Rv ------------------------------------------MN------
MMAR_0733|M.marinum_M ------------------------------------------MN------
MAV_4733|M.avium_104 ------------------------------------------MN------
Mflv_0182|M.gilvum_PYR-GCK ------------------------------------------MTSTSPTE
Mvan_0723|M.vanbaalenii_PYR-1 ------------------------------------------MT------
MAB_4198|M.abscessus_ATCC_1997 ------------------------------------------MS------
MUL_3276|M.ulcerans_Agy99 MRQFSDRIDAGRKLGRRLEFLRGQDIVVLGLPRGGVPVAFEVAKALHAPL
MSMEG_0824|M.smegmatis_MC2_155 LEGLEAIAGVAHEPEA----DPRGVVVLTHG----AGGNRDGALLTRICD
TH_1511|M.thermoresistible__bu ---LEEIAGVAHHPTG----APAGAVVLTHG----AGGDRDSALLQRVCD
Mb0429c|M.bovis_AF2122/97 ---LDQIAGVAHQPAG----PPHGVVVLTHG----AGGSRESTLLQQVCA
Rv0421c|M.tuberculosis_H37Rv ---LDQIAGVAHQPAG----PPHGVVVLTHG----AGGSRESTLLQQVCA
MMAR_0733|M.marinum_M ---LDQIAGIAHEPVTGPGQPPNGIVILTHG----AGGNRDSLLLQQVCD
MAV_4733|M.avium_104 ---LDRIAGIAHRPDG----TPEGVVVLTHG----AGGNRDSPLLQQVCD
Mflv_0182|M.gilvum_PYR-GCK ---IDAIAGVSHHPDG----TPRGGVALTHG----AGGSRESPMLVALCD
Mvan_0723|M.vanbaalenii_PYR-1 ---LEDITGIAHRPDG----IPAGVVALTHG----AGGNRESPMLQALCE
MAB_4198|M.abscessus_ATCC_1997 TEELPDIAGIAHHPDG----HPRGAVVLTHG----AGGSCHSPMLRLLCT
MUL_3276|M.ulcerans_Agy99 DVLLVRKLGVPLHSELAFGAIGEGGVQVINSAVVHEAGLGEQEMAAVETA
: *:. .. * * : :. .* . :
MSMEG_0824|M.smegmatis_MC2_155 EWAARGWLAIRYN-----LPYR--------RRRPKGPPSGSAQA-DQEGV
TH_1511|M.thermoresistible__bu EWASRGWLAVRYN-----LPYR--------RRRPKGPPSNSAAT-DQQGV
Mb0429c|M.bovis_AF2122/97 EWTRRGWLAVRYN-----LPYR--------RRRPTGPPSGSGSG-DRAGI
Rv0421c|M.tuberculosis_H37Rv EWTRRGWLAVRYN-----LPYR--------RRRPTGPPSGSGSG-DRAGI
MMAR_0733|M.marinum_M AWAQRGWLAVRYN-----LPYR--------RRRPKGPPSGSAAT-DRAGI
MAV_4733|M.avium_104 EWAQRGWLAVRYN-----LPFR--------RRRPTGPPSGSGAA-DRAGI
Mflv_0182|M.gilvum_PYR-GCK EWARRGFLAVRYN-----LPYR--------RRRPKGPPSGSSAA-DIAGI
Mvan_0723|M.vanbaalenii_PYR-1 EWARRGWLAVRYN-----LPYR--------RRRPKGPPSGSATA-DMAGI
MAB_4198|M.abscessus_ATCC_1997 AWAERGWLAIRFD-----MPFR--------RNRPSGPPSASSADKDRAGI
MUL_3276|M.ulcerans_Agy99 QWAELQRRVQRYRGDRHPIPLRGRIAVIVDDGVATGATAAAACQVARAQG
*: . *: :* * ..*..: :.
MSMEG_0824|M.smegmatis_MC2_155 AEAIAFARGLTDG--------------------PVLAGGHSYG-------
TH_1511|M.thermoresistible__bu AEAIRWAHSVTDG--------------------PVIAGGHSYG-------
Mb0429c|M.bovis_AF2122/97 VEAIQLCRGLAEG--------------------PLIAGGHSYG-------
Rv0421c|M.tuberculosis_H37Rv VEAIQLCRGLAEG--------------------PLIAGGHSYG-------
MMAR_0733|M.marinum_M VEAIELCRGLAEG--------------------PLIAGGHSYG-------
MAV_4733|M.avium_104 VEAITLCRGLADG--------------------PLIAGGHSYG-------
Mflv_0182|M.gilvum_PYR-GCK VEAVATVRALVDG--------------------PVLAGGHSYG-------
Mvan_0723|M.vanbaalenii_PYR-1 VEAVSAVRALADG--------------------PVIAGGHSYG-------
MAB_4198|M.abscessus_ATCC_1997 AEVINKARAMVDG--------------------PLLAGGHSYG-------
MUL_3276|M.ulcerans_Agy99 ASRVILAVPIGATDTAPRFTEYADEVVCLETPTPYFAVGQGYDNFTQTSD
.. : : * :* *:.*.
MSMEG_0824|M.smegmatis_MC2_155 ----------------------------------------------GRMT
TH_1511|M.thermoresistible__bu ----------------------------------------------GRMT
Mb0429c|M.bovis_AF2122/97 ----------------------------------------------GRQT
Rv0421c|M.tuberculosis_H37Rv ----------------------------------------------GRQT
MMAR_0733|M.marinum_M ----------------------------------------------GRQT
MAV_4733|M.avium_104 ----------------------------------------------GRQT
Mflv_0182|M.gilvum_PYR-GCK ----------------------------------------------GRMT
Mvan_0723|M.vanbaalenii_PYR-1 ----------------------------------------------GRLT
MAB_4198|M.abscessus_ATCC_1997 ----------------------------------------------GRQT
MUL_3276|M.ulcerans_Agy99 QEVVTLLDRARSEFGAGHQPPVPARRDDGVRVLAGPASVIGRLTIPDRPT
.* *
MSMEG_0824|M.smegmatis_MC2_155 SMVAAEHG------------------GMDVLTLFSYPVHPPGKPERARTE
TH_1511|M.thermoresistible__bu SMVVAGRNPEA-------------MPRLAALTLFSYPVHPPGKPERTRTD
Mb0429c|M.bovis_AF2122/97 SMVVAAGQAP-----------------VDVLTLFSYPVHPPGKPERVRTE
Rv0421c|M.tuberculosis_H37Rv SMVVAAGQAP-----------------VDVLTLFSYPVHPPGKPERVRTE
MMAR_0733|M.marinum_M SMVVAAAQAP-----------------VDVLTLFSYPVHPPGKPERARTE
MAV_4733|M.avium_104 SMVVAAGDAA-----------------VDVLTLFSYPVHPPGKPERARTE
Mflv_0182|M.gilvum_PYR-GCK SMAVADGLA------------------LDVLTLFSYPLHPPGKPERARTE
Mvan_0723|M.vanbaalenii_PYR-1 SMAVADGLR------------------VDVLTLFSYPLHPPGKPERARTE
MAB_4198|M.abscessus_ATCC_1997 SMLVAEKGP-----------------IVDVLTLFSYPLHPPGKPDRLRIE
MUL_3276|M.ulcerans_Agy99 GIVVFAHGSGSSRHSPRNRYVAEVLNQAGLATLLLDLLTPEEEHNRANVF
.: . **: : * : :* .
MSMEG_0824|M.smegmatis_MC2_155 HL-------------------------------------------PNITG
TH_1511|M.thermoresistible__bu HL-------------------------------------------RAITV
Mb0429c|M.bovis_AF2122/97 HL-------------------------------------------PGIAV
Rv0421c|M.tuberculosis_H37Rv HL-------------------------------------------PGIAV
MMAR_0733|M.marinum_M HL-------------------------------------------PDITV
MAV_4733|M.avium_104 HL-------------------------------------------PAITV
Mflv_0182|M.gilvum_PYR-GCK HL-------------------------------------------PRITV
Mvan_0723|M.vanbaalenii_PYR-1 HL-------------------------------------------PRITV
MAB_4198|M.abscessus_ATCC_1997 HL-------------------------------------------PDIQV
MUL_3276|M.ulcerans_Agy99 DIGLLARRLVDVTGWLAAQPDTTALPVGFFGASTGGGAALVAAAHPGVKV
.: :
MSMEG_0824|M.smegmatis_MC2_155 PTVFTHGSSDPFG---------------------TIGEVTAAAALINGPT
TH_1511|M.thermoresistible__bu PTVFTHGSSDPFG---------------------SLDEVRAAAALIPART
Mb0429c|M.bovis_AF2122/97 PTVFTHGTADPFG---------------------TLAQVRSAAAMVSAPT
Rv0421c|M.tuberculosis_H37Rv PTVFTHGTADPFG---------------------TLAQVRSAAAMVSAPT
MMAR_0733|M.marinum_M PTVFTHGTSDPFG---------------------TPAEVRAAAALIAAPT
MAV_4733|M.avium_104 PTVFTHGTSDPFG---------------------TPEELNAAAALVGGRT
Mflv_0182|M.gilvum_PYR-GCK PTVFTHGTADPFG---------------------TLDELRPAAALIGAPV
Mvan_0723|M.vanbaalenii_PYR-1 PTVFTHGTADPFG---------------------TLDELRSAADLVAGPT
MAB_4198|M.abscessus_ATCC_1997 PTVFTHGTSDAFG---------------------TIAELKEASVLIPGGA
MUL_3276|M.ulcerans_Agy99 QAVVSRGGRPDLAGDALREVHAPTLPIVGGRDEAVLELNRQAQAAIPAPC
:*.::* :. * : .
MSMEG_0824|M.smegmatis_MC2_155 EVVAIDGARHDLA--SKTHNVPALAVDAALRMLDIV--
TH_1511|M.thermoresistible__bu EVVAVAGARHDLG--SRDIDVAAAAVTAALQLVA----
Mb0429c|M.bovis_AF2122/97 EVVEITGARHDLG--SKTLDVARLAVDAALRLSAGQIA
Rv0421c|M.tuberculosis_H37Rv EVVEITGARHDLG--SKTLDVARLAVDAALRLSAGQIA
MMAR_0733|M.marinum_M EVVEITGARHDLG--SKTLDVAGLAVAAALRLLGPA--
MAV_4733|M.avium_104 AVVEIASARHDLR--SKTLNVAALAVDAALQLLGRN--
Mflv_0182|M.gilvum_PYR-GCK EIVEVTGARHDLG--SKKLDVPALAVDGALRLLG----
Mvan_0723|M.vanbaalenii_PYR-1 EIVEVTGARHDLN--SKKFDVPALAVDAALRMLG----
MAB_4198|M.abscessus_ATCC_1997 AIVEIAGARHDLG--SKTIDVPALAIDAALTALKS---
MUL_3276|M.ulcerans_Agy99 ELVVVPGATHLFEEPGALEQVATLARDWFLGHLRHH--
:* : .* * : . :*. * *