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M. tuberculosis H37Rv Rv0421c (-)

annotation: hypothetical protein Rv0421c
coordinates: 507132 - 507761
length: 209

NLDQIAGVAHQPAGPPHGVVVLTHGAGGSRESTLLQQVCAEWTRRGWLAVRYNLPYRRRRPTGPPSGSGS
GDRAGIVEAIQLCRGLAEGPLIAGGHSYGGRQTSMVVAAGQAPVDVLTLFSYPVHPPGKPERVRTEHLPG
IAVPTVFTHGTADPFGTLAQVRSAAAMVSAPTEVVEITGARHDLGSKTLDVARLAVDAALRLSAGQIA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0421c--100% (209)hypothetical protein Rv0421c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0429c-1e-119100.00% (209) hypothetical protein Mb0429c
M. gilvum PYR-GCKMflv_0182-8e-8372.64% (201) hypothetical protein Mflv_0182
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4198-5e-7362.50% (200) hypothetical protein MAB_4198
M. marinum MMMAR_0733-5e-9882.61% (207) hypothetical protein MMAR_0733
M. avium 104MAV_4733-9e-9480.30% (203) hypothetical protein MAV_4733
M. smegmatis MC2 155MSMEG_0824-3e-8068.66% (201) hypothetical protein MSMEG_0824
M. thermoresistible (build 8)TH_1511-8e-7866.19% (210) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0723-4e-8573.40% (203) hypothetical protein Mvan_0723

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0182|M.gilvum_PYR-GCK          MTSTSPTE---IDAIAGVSHHPDG----TPRGGVALTHGAGGSRESPMLV
Mvan_0723|M.vanbaalenii_PYR-1       MT---------LEDITGIAHRPDG----IPAGVVALTHGAGGNRESPMLQ
Rv0421c|M.tuberculosis_H37Rv        MN---------LDQIAGVAHQPAG----PPHGVVVLTHGAGGSRESTLLQ
Mb0429c|M.bovis_AF2122/97           MN---------LDQIAGVAHQPAG----PPHGVVVLTHGAGGSRESTLLQ
MMAR_0733|M.marinum_M               MN---------LDQIAGIAHEPVTGPGQPPNGIVILTHGAGGNRDSLLLQ
MAV_4733|M.avium_104                MN---------LDRIAGIAHRPDG----TPEGVVVLTHGAGGNRDSPLLQ
MSMEG_0824|M.smegmatis_MC2_155      MARDARQTLEGLEAIAGVAHEPEA----DPRGVVVLTHGAGGNRDGALLT
TH_1511|M.thermoresistible__bu      MS---------LEEIAGVAHHPTG----APAGAVVLTHGAGGDRDSALLQ
MAB_4198|M.abscessus_ATCC_1997      MS------TEELPDIAGIAHHPDG----HPRGAVVLTHGAGGSCHSPMLR
                                    *          :  *:*::*.*       * * * *******. .. :* 

Mflv_0182|M.gilvum_PYR-GCK          ALCDEWARRGFLAVRYNLPYRRRRPKGPPSGSSAA-DIAGIVEAVATVRA
Mvan_0723|M.vanbaalenii_PYR-1       ALCEEWARRGWLAVRYNLPYRRRRPKGPPSGSATA-DMAGIVEAVSAVRA
Rv0421c|M.tuberculosis_H37Rv        QVCAEWTRRGWLAVRYNLPYRRRRPTGPPSGSGSG-DRAGIVEAIQLCRG
Mb0429c|M.bovis_AF2122/97           QVCAEWTRRGWLAVRYNLPYRRRRPTGPPSGSGSG-DRAGIVEAIQLCRG
MMAR_0733|M.marinum_M               QVCDAWAQRGWLAVRYNLPYRRRRPKGPPSGSAAT-DRAGIVEAIELCRG
MAV_4733|M.avium_104                QVCDEWAQRGWLAVRYNLPFRRRRPTGPPSGSGAA-DRAGIVEAITLCRG
MSMEG_0824|M.smegmatis_MC2_155      RICDEWAARGWLAIRYNLPYRRRRPKGPPSGSAQA-DQEGVAEAIAFARG
TH_1511|M.thermoresistible__bu      RVCDEWASRGWLAVRYNLPYRRRRPKGPPSNSAAT-DQQGVAEAIRWAHS
MAB_4198|M.abscessus_ATCC_1997      LLCTAWAERGWLAIRFDMPFRRNRPSGPPSASSADKDRAGIAEVINKARA
                                     :*  *: **:**:*:::*:**.**.**** *.   *  *:.*.:   :.

Mflv_0182|M.gilvum_PYR-GCK          LVDGPVLAGGHSYGGRMTSMAVADGLA-----LDVLTLFSYPLHPPGKPE
Mvan_0723|M.vanbaalenii_PYR-1       LADGPVIAGGHSYGGRLTSMAVADGLR-----VDVLTLFSYPLHPPGKPE
Rv0421c|M.tuberculosis_H37Rv        LAEGPLIAGGHSYGGRQTSMVVAAGQAP----VDVLTLFSYPVHPPGKPE
Mb0429c|M.bovis_AF2122/97           LAEGPLIAGGHSYGGRQTSMVVAAGQAP----VDVLTLFSYPVHPPGKPE
MMAR_0733|M.marinum_M               LAEGPLIAGGHSYGGRQTSMVVAAAQAP----VDVLTLFSYPVHPPGKPE
MAV_4733|M.avium_104                LADGPLIAGGHSYGGRQTSMVVAAGDAA----VDVLTLFSYPVHPPGKPE
MSMEG_0824|M.smegmatis_MC2_155      LTDGPVLAGGHSYGGRMTSMVAAEHG-----GMDVLTLFSYPVHPPGKPE
TH_1511|M.thermoresistible__bu      VTDGPVIAGGHSYGGRMTSMVVAGRNPEAMPRLAALTLFSYPVHPPGKPE
MAB_4198|M.abscessus_ATCC_1997      MVDGPLLAGGHSYGGRQTSMLVAEKGP----IVDVLTLFSYPLHPPGKPD
                                    :.:**::********* *** .*         : .*******:******:

Mflv_0182|M.gilvum_PYR-GCK          RARTEHLPRITVPTVFTHGTADPFGTLDELRPAAALIGAPVEIVEVTGAR
Mvan_0723|M.vanbaalenii_PYR-1       RARTEHLPRITVPTVFTHGTADPFGTLDELRSAADLVAGPTEIVEVTGAR
Rv0421c|M.tuberculosis_H37Rv        RVRTEHLPGIAVPTVFTHGTADPFGTLAQVRSAAAMVSAPTEVVEITGAR
Mb0429c|M.bovis_AF2122/97           RVRTEHLPGIAVPTVFTHGTADPFGTLAQVRSAAAMVSAPTEVVEITGAR
MMAR_0733|M.marinum_M               RARTEHLPDITVPTVFTHGTSDPFGTPAEVRAAAALIAAPTEVVEITGAR
MAV_4733|M.avium_104                RARTEHLPAITVPTVFTHGTSDPFGTPEELNAAAALVGGRTAVVEIASAR
MSMEG_0824|M.smegmatis_MC2_155      RARTEHLPNITGPTVFTHGSSDPFGTIGEVTAAAALINGPTEVVAIDGAR
TH_1511|M.thermoresistible__bu      RTRTDHLRAITVPTVFTHGSSDPFGSLDEVRAAAALIPARTEVVAVAGAR
MAB_4198|M.abscessus_ATCC_1997      RLRIEHLPDIQVPTVFTHGTSDAFGTIAELKEASVLIPGGAAIVEIAGAR
                                    * * :**  *  *******::*.**:  ::  *: :: . . :* : .**

Mflv_0182|M.gilvum_PYR-GCK          HDLGSKKLDVPALAVDGALRLLG----
Mvan_0723|M.vanbaalenii_PYR-1       HDLNSKKFDVPALAVDAALRMLG----
Rv0421c|M.tuberculosis_H37Rv        HDLGSKTLDVARLAVDAALRLSAGQIA
Mb0429c|M.bovis_AF2122/97           HDLGSKTLDVARLAVDAALRLSAGQIA
MMAR_0733|M.marinum_M               HDLGSKTLDVAGLAVAAALRLLGPA--
MAV_4733|M.avium_104                HDLRSKTLNVAALAVDAALQLLGRN--
MSMEG_0824|M.smegmatis_MC2_155      HDLASKTHNVPALAVDAALRMLDIV--
TH_1511|M.thermoresistible__bu      HDLGSRDIDVAAAAVTAALQLVA----
MAB_4198|M.abscessus_ATCC_1997      HDLGSKTIDVPALAIDAALTALKS---
                                    *** *:  :*.  *: .**