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TAGTAPRPAPATPSIDEWPLQVDKPLSAAYDPFFGPAPQGWEGTAPGTPLRRRRVRLGLFGLIPLKLHAW QVLYRSTDLHGNPETTVTTVVVPQRATADSPLLAFQSAIDAVTPKRFPSYYLQQGSFGLTQSQNEFLLVV AALTKGWVVTISDHEGPHGLWMVARQPGYHVLDGLRATIAASGDDGIPQLSWQTPVAVWGYSGGGTATAW AAELAGEYAPELNMVGALIGAPAAQPGPLVHYHCARPASGLIIPVLAAMMRAHPPAREFLERHLNRRGRR IVEKSERMTLLETVLRWPFLDFNKILDRPLEEVMDGPEITALTDEMTLGQRTPTAPVYLYHPIHDLLLPI QYTDQLAEDYIAGGAHVTYRRDRASEHIVLALAGGSDALAWLDERLTGKALPARSDVQTVFSTSLTLRAI RMFMRWQRGIIQLLSGKL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1392c | - | - | 100% (439) | hypothetical protein MAB_1392c |
| M. abscessus ATCC 19977 | MAB_4134 | - | 2e-83 | 40.62% (421) | putative lipase |
| M. abscessus ATCC 19977 | MAB_2676 | - | 1e-75 | 39.21% (380) | hypothetical protein MAB_2676 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1618c | - | 5e-85 | 41.77% (395) | hypothetical protein Mb1618c |
| M. gilvum PYR-GCK | Mflv_3621 | - | 1e-82 | 42.30% (383) | triacylglycerol lipase |
| M. tuberculosis H37Rv | Rv1592c | - | 4e-85 | 42.03% (395) | hypothetical protein Rv1592c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2389 | - | 2e-85 | 42.78% (381) | hypothetical protein MMAR_2389 |
| M. avium 104 | MAV_3194 | - | 7e-83 | 42.14% (401) | secretory lipase family protein |
| M. smegmatis MC2 155 | MSMEG_3197 | - | 8e-86 | 43.35% (376) | lipase |
| M. thermoresistible (build 8) | TH_2810 | - | 4e-83 | 40.59% (409) | PUTATIVE Triacylglycerol lipase |
| M. ulcerans Agy99 | MUL_1566 | - | 1e-85 | 42.78% (381) | hypothetical protein MUL_1566 |
| M. vanbaalenii PYR-1 | Mvan_2796 | - | 2e-82 | 42.26% (381) | triacylglycerol lipase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1618c|M.bovis_AF2122/97 ---------MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFP
Rv1592c|M.tuberculosis_H37Rv ---------MVEPGNLAGATGAEWIGRPPHEELQRKVRPLLPSDDPFYFP
MMAR_2389|M.marinum_M MPKAMKGALMVKLGSLADARAAEWIGRPPHEELQRKVRPLLPSDDPFYDP
MUL_1566|M.ulcerans_Agy99 ---------MVKLGSLADARAAGWIGRPPHEELQRKVRPLLPSDDPFYDP
MAV_3194|M.avium_104 ---------MAELGNLAGTHGAEWIARPPHEELQRKVRPLLPSDDPFYQP
MSMEG_3197|M.smegmatis_MC2_155 ----------MDLSSAAKAADAEWIGRAPHEELDRDARPGLPGEDPFYLP
Mflv_3621|M.gilvum_PYR-GCK ----------MDLGNVARSTGAEWIGQPRHEELRPRTRPVIPADDPFYEP
Mvan_2796|M.vanbaalenii_PYR-1 ----------MDLGNVARSTGAEWIGQPFHEPLRPRSRPMIPAKDDFYEP
TH_2810|M.thermoresistible__bu ----------MDLGSAAQSTGAEWIGRPTHEALR-RTRPILPERDPFYEP
MAB_1392c|M.abscessus_ATCC_199 ----------MTAGTAPRPAPAT---PSIDEWPLQVDKPLSAAYDPFFGP
.. . . * . .* :* . * *: *
Mb1618c|M.bovis_AF2122/97 -PAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRTTNMYGNPEAT
Rv1592c|M.tuberculosis_H37Rv -PAGYQHAVPGTVLRSRDVELAFMGLIPQPVTATQLLYRTTNMYGNPEAT
MMAR_2389|M.marinum_M -PAGYHHAEPGTVLRSREVELAFLGLIPQSITATQLLYRTTDMYGNPEAT
MUL_1566|M.ulcerans_Agy99 -PAGYHHAEPGTVLRSREVELAFLGLIPQSITATQLLYRTTDMYGNPEAT
MAV_3194|M.avium_104 -PLGFQHAEPGTVLRSRDVELAFLGLIPQPIKAVQLLYRTMDMNGEPEAT
MSMEG_3197|M.smegmatis_MC2_155 -PAGYHHAEPGTVLRSRDVELAFLGLVPQALHATQLLYRTTDRNGAPEAA
Mflv_3621|M.gilvum_PYR-GCK -PEGYEHARPGTVLRSRDVELAFLGLIPQKFSATQLLYRTTDLYGQPQAT
Mvan_2796|M.vanbaalenii_PYR-1 -PAGFEHARPGTVLRSRDVELAFLGVIPQKFTATQLLYRTTDLNGEAQAT
TH_2810|M.thermoresistible__bu -PPGFEHARPGTVLRSRDVELAFMGLIPQKFTATQLLYRTTGFDGRPRAT
MAB_1392c|M.abscessus_ATCC_199 APQGWEGTAPGTPLRRRRVRLGLFGLIPLKLHAWQVLYRSTDLHGNPETT
* *:. : *** ** * *.*.::*::* . * *:***: . * ..::
Mb1618c|M.bovis_AF2122/97 VTTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQ
Rv1592c|M.tuberculosis_H37Rv VTTVIVPAELAPGQTCPLLSYQCAIDAMSSRCFPSYALRRRAKALGSLTQ
MMAR_2389|M.marinum_M VTTVILPAEVAPGQTYPLLSYQCAIDAMSSRCFPSYALRRGAKAIGSLTQ
MUL_1566|M.ulcerans_Agy99 VTTVILPAEVAPGQTYPLLSYQCAIDAMSSRCFPSYALRRGAKAIGSLTQ
MAV_3194|M.avium_104 VTTVIVPADAVPGRPCPLLSYQCAIDAVSSRCFPSYALRRRAKALGSIGQ
MSMEG_3197|M.smegmatis_MC2_155 VTTVIMPPDARAG--CPIVSYQCAIDAISATCFPSYALRRHAKVTGGLAQ
Mflv_3621|M.gilvum_PYR-GCK VTTVLAPTERTDRRPLPIVSYQCAIDAVAGRCFPSYALRRGAKALGAVAQ
Mvan_2796|M.vanbaalenii_PYR-1 VTTVVVPSERTSDGPLPIVSYQCAIDAVAGRCFPSYALRRGAKALGSFAQ
TH_2810|M.thermoresistible__bu VTTVVVPAERDKNGRCPVVSYQCAIDAVTSRCFPSYALRRGARAVGALAQ
MAB_1392c|M.abscessus_ATCC_199 VTTVVVPQRATADS--PLLAFQSAIDAVTPKRFPSYYLQQGSFGL-TQSQ
****: * *::::*.****:: **** *:: : *
Mb1618c|M.bovis_AF2122/97 MELLMISAALAEGWAVSVPDHEGPKGLWGSPYEPGYRVLDGIRAALNSER
Rv1592c|M.tuberculosis_H37Rv MELLMISAALAEGWAVSVPDHEGPKGLWGSPYEPGYRVLDGIRAALNSER
MMAR_2389|M.marinum_M LELLLITAAVAEGWAVSVPDHEGVRGLWGTPYEPGYRVLDGIRAALSAER
MUL_1566|M.ulcerans_Agy99 LELLLITAAVAEGWAVSVPDHEGVRGLWGTPYEPGYRVLDGIRAALSAER
MAV_3194|M.avium_104 FELFLITAAVAEGWAVSVPDHEGLRGLWGAPYEPGYRVLDGIRAALGSER
MSMEG_3197|M.smegmatis_MC2_155 FELLLITAALAEGWAVSVPDHEGLDGMWGAPYEPGYHVLDGLRAALNSER
Mflv_3621|M.gilvum_PYR-GCK FEFLLIAAALAEGWAVSVPDHEGTTGMWGAPFEPGYHVLDGIRAAVNHRP
Mvan_2796|M.vanbaalenii_PYR-1 FEFLLVAAALAEGWAVSVPDHEGTSGMWGAPHEPGYHVLDGVRAALNHGP
TH_2810|M.thermoresistible__bu FEFLLIAAALAEGWAVSVPDHEGPDGSWGAPLEPGYHILDGLRAALGYER
MAB_1392c|M.abscessus_ATCC_199 NEFLLVVAALTKGWVVTISDHEGPHGLWMVARQPGYHVLDGLRATIAASG
*:::: **:::**.*::.**** * * . :***::***:**::
Mb1618c|M.bovis_AF2122/97 ----VGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPV
Rv1592c|M.tuberculosis_H37Rv ----VGLSPATPIGLWGYSGGGLASAWAAEACGEYAPDLDIVGAVLGSPV
MMAR_2389|M.marinum_M ----LALPQSAPIGLWGYSGGGLASAWAAEMCGEYAPELNIVGAVLGSPV
MUL_1566|M.ulcerans_Agy99 ----LALPQSAPIGLWGYSGGGLASAWAAEMCGEYAPDLNIVGAVLGSPV
MAV_3194|M.avium_104 ----LGLSPSAPIGLWGYSGGGLASAWAAETCAEYAPELNVVGAVLGSPV
MSMEG_3197|M.smegmatis_MC2_155 ----LPLTDASPIGLWGYSGGGLASGWAAEMSGSYAPELNIVGAVLGSPV
Mflv_3621|M.gilvum_PYR-GCK ----LGLAEDAPVGLWGYSGGGLASAWAAEVHDSYAPELNVVGAVLGSPV
Mvan_2796|M.vanbaalenii_PYR-1 ----LGLSPDAPVGLWGYSGGGLASAWAAEVQDAYAPELNVVGAVLGSPV
TH_2810|M.thermoresistible__bu ----LNLAVDAPVGLWGYSGGGLASAWAAEVCRDYAPDLNVVGAVLGSPV
MAB_1392c|M.abscessus_ATCC_199 DDGIPQLSWQTPVAVWGYSGGGTATAWAAELAGEYAPELNMVGALIGAPA
*. :*:.:******* *:.**** ***:*::***::*:*.
Mb1618c|M.bovis_AF2122/97 GDLGHTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLE
Rv1592c|M.tuberculosis_H37Rv GDLGHTFRRLNGTLLAGLPALVVAALQHSYPGLARVIKEHANDEGRQLLE
MMAR_2389|M.marinum_M GDLGNTFRRLNGTLLAGLPAMVVAALGHAYPGLDRVIKQHANEDGIELLE
MUL_1566|M.ulcerans_Agy99 GDLGNTFRRLNGTLLAGLPAMVVAALGHAYPGLDRVIKQHANEDGIELLE
MAV_3194|M.avium_104 GDLGNTFRRLNGSFLSGLPALVVAALAHIYPDLDRVIKEHANEEGRALLD
MSMEG_3197|M.smegmatis_MC2_155 GDLGHTFRRLNGTVFSGLPALVVAALADIYPGLNRVIAEHATTEGRKLLQ
Mflv_3621|M.gilvum_PYR-GCK GDLGHAFRRLNGSIYSGLPAMVVAALTHVYPDLNRIIQQHATVEGKAMLA
Mvan_2796|M.vanbaalenii_PYR-1 GDLGHTFRRLNGSIYAGLPALVVAALTHIYPDLHRVIQEHATEDGKVMLA
TH_2810|M.thermoresistible__bu GDLGSAFRRLNGSLYAGLPAMVVAALAHIFPEVDQIIDEHATETGKAMLQ
MAB_1392c|M.abscessus_ATCC_199 AQPGPLVHYHCARPASGLIIPVLAAMMRAHPPAREFLERHLNRRGRRIVE
.: * .: . :** *:**: .* ..: .* . * ::
Mb1618c|M.bovis_AF2122/97 QLTEMTTVDAVIRMAGRDMGDFLDEPLEDILSTPEVSHVFGDTKLGSAVP
Rv1592c|M.tuberculosis_H37Rv QLTEMTTVDAVIRMAGRDMGDFLDEPLEDILSTPEISHVFGDTKLGSAVP
MMAR_2389|M.marinum_M RLEQMTTAEAVIRMANNDLGHYLDEPLDDVLSTPEVVHVFDDIKLGAAVP
MUL_1566|M.ulcerans_Agy99 RLEQMTTAEAVIRMANNDLGHYLDEPLEDVLSTPEVVHVFDDIKLGAAVP
MAV_3194|M.avium_104 SLEKMTTVEAVIRMAGKNMGDYLDAPLEQILSTPEVTYVFDHIRLGAAVP
MSMEG_3197|M.smegmatis_MC2_155 RLHKMSTIEAVLRLARKDMDDLVDLPLEQILDSPEVTEVFDDIKLGVATP
Mflv_3621|M.gilvum_PYR-GCK RIEKMTTAHAMLSLVGKDMAHWVDRPLEEILLTPEVQHVFDSIKLGTSAP
Mvan_2796|M.vanbaalenii_PYR-1 RIEKMTTAHAMISLVGRDMAHMIDRPLEEILLSPEVQHVFDSIKLGTAAP
TH_2810|M.thermoresistible__bu RVEKMTTAHAVLRMIGMDMGKLVDQPLEEILQTPAMQRVFDRIKLGSAIP
MAB_1392c|M.abscessus_ATCC_199 KSERMTLLETVLRWPFLDFNKILDRPLEEVMDGPEITALTDEMTLGQRTP
.*: .::: :: . :* **:::: * : : . ** *
Mb1618c|M.bovis_AF2122/97 TPPVLIVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPL
Rv1592c|M.tuberculosis_H37Rv TPPVLIVQAVHDYLIDVSDIDALADSYTAGGANVTYHRDLFSEHVSLHPL
MMAR_2389|M.marinum_M APPVLIVQAVHDYLISVDDIDTLAESYSTGGARVTYHRDAFNEHMMLHPL
MUL_1566|M.ulcerans_Agy99 APPVLIVQAVHDYLISVDDIDTLAESYSTGGARVTYHRDAFNEHMMLHPL
MAV_3194|M.avium_104 TPPVLIVQAVHDYLIDVHDIDVLADAYSAGGAQVTYHRDAFNEHMMLHPL
MSMEG_3197|M.smegmatis_MC2_155 NPPVLLIQAVHDELISVSSIDELAEKYLTGGASVTYHRDLFSEHLLLHPM
Mflv_3621|M.gilvum_PYR-GCK KVPVLIVQAVHDRIISVDDIDELTETYTAGGASVTYHRDMFSEHLLLHPM
Mvan_2796|M.vanbaalenii_PYR-1 KVPLLIVQAVHDRIISVDDIDALTETYTSGGASVTYHRDMLSEHLLLHPM
TH_2810|M.thermoresistible__bu APPVLLVQACHDRIVSVDDIDTLADTYIEGGVRVTYHRDMFSEHMLLHPM
MAB_1392c|M.abscessus_ATCC_199 TAPVYLYHPIHDLLLPIQYTDQLAEDYIAGGAHVTYRRDRASEHIVLALA
*: : :. ** :: : * *:: * **. ***:** .**: *
Mb1618c|M.bovis_AF2122/97 SAPMTLRWLTDRFAGKPLTDH-RVRTTWPTIFNPMTYAGMARLAVIAAKV
Rv1592c|M.tuberculosis_H37Rv SAPMTLRWLTDRFAGKPLTDH-RVRTTWPTIFNPMTYAGMARLAVIAAKV
MMAR_2389|M.marinum_M SAPMTLRWLTDRFAGLPLTEH-VIRTTWPTMFNPMTYAGMARLAVIAAKM
MUL_1566|M.ulcerans_Agy99 SAPMTLRWLTDRFAGLPLTEH-VIRTTWPTMFNPMTYAGMARLAVTAAKM
MAV_3194|M.avium_104 SAPMTLRWLTDRFEGRPVTEH-LIRTTWPTMFNPMTYVGMARLLKIAAKV
MSMEG_3197|M.smegmatis_MC2_155 SAPMALRWLTDRFAARPLTAN-LVRSKWPTLLNPVTYVGMARLAGIAAKV
Mflv_3621|M.gilvum_PYR-GCK SAPMTLRWLRDRFAGRPISAH-IARTKWPTLLNPSTYRGMLTLGKITAKV
Mvan_2796|M.vanbaalenii_PYR-1 SAPMTLRWLRDRFAGRPLRTH-ISRTKWPTLLNPSTYRGMLTLGKITAKV
TH_2810|M.thermoresistible__bu SAPMTLRWLRDRFAGQPLKHN-LTRTKWPTMFNPSTYRGMLRLGLITAKV
MAB_1392c|M.abscessus_ATCC_199 GGSDALAWLDERLTGKALPARSDVQTVFSTSLTLRAIRMFMRWQRGIIQL
... :* ** :*: . .: . :: :.* :. : : ::
Mb1618c|M.bovis_AF2122/97 ITGRKLSRRPL---------------------------------------
Rv1592c|M.tuberculosis_H37Rv ITGRKLSRRPL---------------------------------------
MMAR_2389|M.marinum_M ITGRKIHRRPL---------------------------------------
MUL_1566|M.ulcerans_Agy99 ITGRKIHRRPL---------------------------------------
MAV_3194|M.avium_104 VTGRKIHRRPL---------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 VTGRALRRSPL---------------------------------------
Mflv_3621|M.gilvum_PYR-GCK VLGRRVERQP----------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 MLGRRVERQP----------------------------------------
TH_2810|M.thermoresistible__bu LTGRRVDRRPXXXRLHAEMIAELRWPGDPDPDSGIDIWAMELDPGQLAVL
MAB_1392c|M.abscessus_ATCC_199 LSGKL---------------------------------------------
: *:
Mb1618c|M.bovis_AF2122/97 --------------------------------------------------
Rv1592c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2389|M.marinum_M --------------------------------------------------
MUL_1566|M.ulcerans_Agy99 --------------------------------------------------
MAV_3194|M.avium_104 --------------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK -----------LSQFDL---------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 -----------LSRFDQ---------------------------------
TH_2810|M.thermoresistible__bu DILRRPDVMTALTEWDAGDALGDYTRERIRSSSALAVVTVEGREPADYLR
MAB_1392c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1618c|M.bovis_AF2122/97 --------------------------------------------------
Rv1592c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2389|M.marinum_M --------------------------------------------------
MUL_1566|M.ulcerans_Agy99 --------------------------------------------------
MAV_3194|M.avium_104 --------------------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3621|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2810|M.thermoresistible__bu GGSALEAVWIRAQQRGLAVHPVSPLFLYAHEEDELRALSPRFASSLVNLR
MAB_1392c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1618c|M.bovis_AF2122/97 -----------------------------------------
Rv1592c|M.tuberculosis_H37Rv -----------------------------------------
MMAR_2389|M.marinum_M -----------------------------------------
MUL_1566|M.ulcerans_Agy99 -----------------------------------------
MAV_3194|M.avium_104 -----------------------------------------
MSMEG_3197|M.smegmatis_MC2_155 -----------------------------------------
Mflv_3621|M.gilvum_PYR-GCK -----------------------------------------
Mvan_2796|M.vanbaalenii_PYR-1 -----------------------------------------
TH_2810|M.thermoresistible__bu REFHDLAGTRRGESQIIVFRLFEAPPASVRSRRRSGGIGVD
MAB_1392c|M.abscessus_ATCC_199 -----------------------------------------