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SRRIESPRRRGGNQMNDTAAIGEVALHARNVRFDFSDSPLQWIPGEPVASHALSALNFMLPAGELFFVEV FGRALPHIRDDKLREEVIGFIGQEQLHSDTHDKALLEYFSQHGIDAQPLHELTERVLATFRQQMDRLPPK LRYRVMVEGIAIIAGIEHLTATAGDWLLNFEFENYGADPVITDMFRWHGAEEVEHRSVAWDLARHVGVGR PRMMAYFIGSCATIPVGLILLSWLLARADPGVPKMSLVRWLRETNRAMKRGATLKWSVLGEGFRSFLRPG FTPESIGDTAQAVAYLAKSPAAKAAAAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4021c | - | - | 100% (309) | hypothetical protein MAB_4021c |
| M. abscessus ATCC 19977 | MAB_0089c | - | 4e-83 | 50.88% (285) | hypothetical protein MAB_0089c |
| M. abscessus ATCC 19977 | MAB_1701 | - | 5e-26 | 31.09% (267) | hypothetical protein MAB_1701 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2799c | - | 3e-52 | 38.03% (305) | hypothetical protein Mb2799c |
| M. gilvum PYR-GCK | Mflv_3425 | - | 6e-59 | 42.66% (286) | hypothetical protein Mflv_3425 |
| M. tuberculosis H37Rv | Rv2777c | - | 3e-52 | 38.03% (305) | hypothetical protein Rv2777c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1931 | - | 2e-52 | 39.58% (288) | hypothetical protein MMAR_1931 |
| M. avium 104 | MAV_3671 | - | 4e-52 | 40.28% (288) | FF domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3675 | - | 7e-60 | 43.40% (288) | metal-dependent hydrolase |
| M. thermoresistible (build 8) | TH_2221 | - | 4e-58 | 41.30% (293) | metal-dependent hydrolase |
| M. ulcerans Agy99 | MUL_2157 | - | 1e-52 | 39.58% (288) | hypothetical protein MUL_2157 |
| M. vanbaalenii PYR-1 | Mvan_3179 | - | 3e-59 | 42.56% (289) | hypothetical protein Mvan_3179 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2799c|M.bovis_AF2122/97 MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
Rv2777c|M.tuberculosis_H37Rv MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
MMAR_1931|M.marinum_M --------------------------------------------------
MUL_2157|M.ulcerans_Agy99 --------------------------------------------------
MAV_3671|M.avium_104 --------------------------------------------------
Mflv_3425|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3179|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2221|M.thermoresistible__bu --------------------------------------------------
MSMEG_3675|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4021c|M.abscessus_ATCC_199 -----------------------------------------------MSR
Mb2799c|M.bovis_AF2122/97 AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
Rv2777c|M.tuberculosis_H37Rv AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMA
MMAR_1931|M.marinum_M -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLPFHYVPNEPLP
MUL_2157|M.ulcerans_Agy99 -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLPFHYVPNEPLP
MAV_3671|M.avium_104 -MVIIDNQAAGPHDAS---VDHERLVLEARDVDFDWAQLPFHYAPGEPFA
Mflv_3425|M.gilvum_PYR-GCK -MLRPRRFSA--------EVDPGPVQIQARKVHFDVSDVPLHWIPGHPVA
Mvan_3179|M.vanbaalenii_PYR-1 -MLRPRRFDA--------EIDPGPVQIQARKVHFDVADVPLHWIPGHPVA
TH_2221|M.thermoresistible__bu -MLRPRRFAT--------EVDPGPVQIQARQVHFDVSGIPLHWIPGHPVA
MSMEG_3675|M.smegmatis_MC2_155 -MLRPLRFDH--------EIDPGPVQIQARKVHFDLSDIPLHWIPGHPVA
MAB_4021c|M.abscessus_ATCC_199 RIESPRRRGGNQMN---DTAAIGEVALHARNVRFDFSDSPLQWIPGEPVA
: : :..*.* ** : *::: *..*..
Mb2799c|M.bovis_AF2122/97 THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
Rv2777c|M.tuberculosis_H37Rv THVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MMAR_1931|M.marinum_M THVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MUL_2157|M.ulcerans_Agy99 THVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQ
MAV_3671|M.avium_104 THVLNVLHLLLPAGEQFFVEVFKQALPLIRDDQLRLDVQGFIGQEGVHSR
Mflv_3425|M.gilvum_PYR-GCK SHVVSVLNILLPAGERWFVETFNEALPLVKDPKLADDIRGFIGQEATHAD
Mvan_3179|M.vanbaalenii_PYR-1 SHVVSVLNIVLPAGERWFVQTFNEALPLVKDPKLADDIRGFIGQEATHAD
TH_2221|M.thermoresistible__bu SNLISLLNVVLPDAERWFVATFNEALPYVKDPKLADDMRGFIGQEATHAD
MSMEG_3675|M.smegmatis_MC2_155 STMVNLFNVVLPVAEHWFVDTFNEALPYVRDPKLADDMRGFIGQEATHAE
MAB_4021c|M.abscessus_ATCC_199 SHALSALNFMLPAGELFFVEVFGRALPHIRDDKLREEVIGFIGQEQLHSD
: :. ::.:** .* :** .* .:** ::* :* :: ****** *:
Mb2799c|M.bovis_AF2122/97 AHSGVVDHFDA-QGVDVTAFTNQIRWLFEKLLGE-SPRRSPRRQYSWLLE
Rv2777c|M.tuberculosis_H37Rv AHSGVVDHFDA-QGVDVTAFTNQIRWLFEKLLGE-SPRRSPRRQYSWLLE
MMAR_1931|M.marinum_M AHSGVLAHFEA-QGVDVTPYTDQIRWLFGKLLAE-KPGRNPRQRHRWLLE
MUL_2157|M.ulcerans_Agy99 AHSGVLAHFEA-QGVDVTPYTDQIRWLFGKLLAE-KPGRNPRQRHRWLLE
MAV_3671|M.avium_104 AHANVLAHFAA-RGIDLRPYTGQIEWLFGTLLGP-RPNWSPRRRQSWLLE
Mflv_3425|M.gilvum_PYR-GCK VHDQVLHDVMVRHGVDPAPILGQVDHLFGKSLAPLDDSADEARRLNHLCD
Mvan_3179|M.vanbaalenii_PYR-1 VHDQVLHEFMVSHGVNPAPILAQIEHMFTGVLAPPDETVDESRRWSHLCD
TH_2221|M.thermoresistible__bu VHEQVMYDFMVEHGVNPEPILAQIEYMFTKVLTP-STSSDPKRRFNNLCE
MSMEG_3675|M.smegmatis_MC2_155 THDKVLEEFLTAHDVHYQPILELVDHVFNTMLAP-KPATDPRRRLNDLCD
MAB_4021c|M.abscessus_ATCC_199 THDKALLEYFSQHGIDAQPLHELTERVLATFRQQ-MDRLPPKLRYRVMVE
.* .: . :.:. . :: : : :
Mb2799c|M.bovis_AF2122/97 QVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKA
Rv2777c|M.tuberculosis_H37Rv QVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKA
MMAR_1931|M.marinum_M QVSFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEHKA
MUL_2157|M.ulcerans_Agy99 QVSFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEHKA
MAV_3671|M.avium_104 QISLVSAIEHYTAILGEWILDSPAHDRIGTDPVMLDMLRWHGAEEVEHKA
Mflv_3425|M.gilvum_PYR-GCK RLWLIAAIEHYTAVMGDFALNCT-WDDHGADPTLVDLFRWHGSEEVEHRS
Mvan_3179|M.vanbaalenii_PYR-1 RLWLIAAIEHYTAVMGDFALNCT-WDDHGADPTLVDLFRWHGSEEVEHRS
TH_2221|M.thermoresistible__bu RLWLIAALEHYTAVLGDFALNCR-WDDHGAHPTMVDLYRWHGAEEVEHRN
MSMEG_3675|M.smegmatis_MC2_155 RLWLIAAIEHYTAVLGDFVLNCA-WDDHHADPTLTDLFRWHGAEEVEHRS
MAB_4021c|M.abscessus_ATCC_199 GIAIIAGIEHLTATAGDWLLNFE-FENYGADPVITDMFRWHGAEEVEHRS
: :::.:** ** *:: *: : :.*.: *: ****:*****:
Mb2799c|M.bovis_AF2122/97 VAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPGTK
Rv2777c|M.tuberculosis_H37Rv VAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPGTK
MMAR_1931|M.marinum_M VAFDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLLAPGTK
MUL_2157|M.ulcerans_Agy99 VAFDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLLAPGTK
MAV_3671|M.avium_104 VAFDTMKHLRAGYWRQVRTQLVVTPAMLLLWIRGVRFMYSRDPYLPPHTK
Mflv_3425|M.gilvum_PYR-GCK VAHDVAVYFHDSYFARIRAMTIAASMLFVFFQRVAWYLTSTDPSVDASWW
Mvan_3179|M.vanbaalenii_PYR-1 VAHDVAMYFHDSYLARIRAMSVAATMLFVFFQRTAWYLVKHDPGVDANWW
TH_2221|M.thermoresistible__bu VAHDVAVYFRDSYVDRIRAMCIAMPLMWAFFERGMWYLVKTDPSVELSWW
MSMEG_3675|M.smegmatis_MC2_155 VAHDVAVYFQDSYLARVRAMTIAATAVYMFFQRGTWAMIRKDPTVDIGWW
MAB_4021c|M.abscessus_ATCC_199 VAWDLARHVGVGRPRMMAYFIGSCATIPVGLILLSWLLARADPGVPKMSL
** * :. . : . : : ** :
Mb2799c|M.bovis_AF2122/97 PRW-RDYFKAARRGLVPGLPRLLRV-VGHYYKPGFHPSQLGGLGAAVDYL
Rv2777c|M.tuberculosis_H37Rv PRW-RDYFKAARRGLVPGLPRLLRV-VGHYYKPGFHPSQLGGLGAAVDYL
MMAR_1931|M.marinum_M PRW-RDYVRSARRGLTPGPWRLIRV-VGDYYKPGFHPSQLGGLERAVDYL
MUL_2157|M.ulcerans_Agy99 PRW-RDYVRSARRGLTPGPWRLIRV-VGDYYKPGFHPSQLGGLERAVDYL
MAV_3671|M.avium_104 PRW-RDYFRAAWRGLVPGPLRFVRA-VANYYRPGFHPSQLGGLQRAVDYL
Mflv_3425|M.gilvum_PYR-GCK KFN-RMRMRDSKLGLLPLYRRLFGANTLSYFRPGYSPEQLGSTAQAVAYL
Mvan_3179|M.vanbaalenii_PYR-1 AFN-RMRMRDSKLGLLPKYRKLFGSSTLGYFRPGYAPEQLGSTAQAVAYL
TH_2221|M.thermoresistible__bu QTQ-RQRCRDSGLGLLPKWRTLFFTNTLDYFRPGFTPEQMGSTAQAVAYL
MSMEG_3675|M.smegmatis_MC2_155 KMH-RLRMRDSKLGLLPKFSTLFGTNTLAYCRPSFTPDQMGSTAQAVAYL
MAB_4021c|M.abscessus_ATCC_199 VRWLRETNRAMKRGATLKWS-VLGEGFRSFLRPGFTPESIGDTAQAVAYL
* : * .. : :*.: *..:*. ** **
Mb2799c|M.bovis_AF2122/97 AVSPAARASH--
Rv2777c|M.tuberculosis_H37Rv AVSPAARASH--
MMAR_1931|M.marinum_M AVSPAARASH--
MUL_2157|M.ulcerans_Agy99 AVSPAARASH--
MAV_3671|M.avium_104 AVSPAARASH--
Mflv_3425|M.gilvum_PYR-GCK AASPAARAAHL-
Mvan_3179|M.vanbaalenii_PYR-1 ASSPAARAAHL-
TH_2221|M.thermoresistible__bu ASSPAARSARL-
MSMEG_3675|M.smegmatis_MC2_155 ASSPAARAAHL-
MAB_4021c|M.abscessus_ATCC_199 AKSPAAKAAAAA
* ****:::