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TTIDQPRALHEAGASSVRGKSVGDREKTAQRLLRSAAERAYDGEVDIDWDAPPVPGLYWATPRRTSLYGT KLWDKLTQEQRIELTRHELGSILSFGIYVETGLSAMLWRQVVEQNGGATDHGRYALTEVSEEARHSTMFG RLVNKMGVEPYTYPKFATRVIRLLGLVPLGPSGLGGLLLVEEVLDRAQRETMMDETVQPHARQLMKIHVL EEARHITYAREELVRQIAERGPVSNAIHRAIFALAVIGIYPVLFNPKAYRAVGIHPLRGFFAFLTSPHYR ENATWVSEPLMRFMHEIGFLDGKFTGRLLRMSRAMPEDILAEIKAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3921c | - | - | 100% (327) | hypothetical protein MAB_3921c |
| M. abscessus ATCC 19977 | MAB_0051 | - | 1e-67 | 42.09% (316) | hypothetical protein MAB_0051 |
| M. abscessus ATCC 19977 | MAB_1535c | - | 2e-65 | 43.67% (300) | hypothetical protein MAB_1535c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0909 | - | 2e-16 | 28.08% (203) | hypothetical protein Mb0909 |
| M. gilvum PYR-GCK | Mflv_0937 | - | 3e-38 | 41.35% (208) | hypothetical protein Mflv_0937 |
| M. tuberculosis H37Rv | Rv0885 | - | 2e-16 | 28.08% (203) | hypothetical protein Rv0885 |
| M. leprae Br4923 | MLBr_02135 | - | 7e-16 | 30.43% (207) | putative transmembrane protein |
| M. marinum M | MMAR_4564 | - | 8e-45 | 37.55% (277) | hypothetical protein MMAR_4564 |
| M. avium 104 | MAV_1064 | - | 1e-44 | 36.82% (277) | hypothetical protein MAV_1064 |
| M. smegmatis MC2 155 | MSMEG_5549 | - | 9e-44 | 33.22% (307) | hypothetical protein MSMEG_5549 |
| M. thermoresistible (build 8) | TH_1805 | - | 3e-14 | 27.09% (203) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4424 | - | 6e-44 | 36.43% (291) | hypothetical protein MUL_4424 |
| M. vanbaalenii PYR-1 | Mvan_5032 | - | 2e-16 | 27.51% (229) | hypothetical protein Mvan_5032 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1805|M.thermoresistible__bu -----------------MEVTD---DAQYVDMLNTLSEGSVRRNFNPYID
Mvan_5032|M.vanbaalenii_PYR-1 MAVKEARTRIIRRWRRNMEIGDGPEDRAYVEKLATLSEGSVRRNFNPYTD
Mb0909|M.bovis_AF2122/97 ----MDRTRIVRRWRRNMDVAD---DAEYVEMLATLSEGSVRRNFNPYTD
Rv0885|M.tuberculosis_H37Rv ----MDRTRIVRRWRRNMDVAD---DAEYVEMLATLSEGSVRRNFNPYTD
MLBr_02135|M.leprae_Br4923 ----MARTRMVRRWRNNMEVRD---DTDYVGMLTTLSEGSVRRNFNPYTD
MMAR_4564|M.marinum_M -----------------MTTAVKPSGPGREEFSERLLRGSVKKSYEPIVD
MUL_4424|M.ulcerans_Agy99 -----------MKGRQAMTTAVKPSGPGREEFSERLLRGSVKKSYEPIVD
MAV_1064|M.avium_104 --MPSDQEDPTMTRAETIRSDARPTGPSREEFSERLLKGSVKKSYEPVVD
MSMEG_5549|M.smegmatis_MC2_155 -----------------MTTSVR-SAATRDEYAERLLKGSVKRSYAPVVD
Mflv_0937|M.gilvum_PYR-GCK ------------------MPAPSAITRDKDDVALRLLKGAAKKSYEPVVD
MAB_3921c|M.abscessus_ATCC_199 ---MTTIDQPRALHEAGASSVRGKSVGDREKTAQRLLRSAAERAYDGEVD
* ..:..: : *
TH_1805|M.thermoresistible__bu IDWDAPEFAVTPDDERWILPATDPLGRHPWYQAQPVKKQIEIGMWRQANV
Mvan_5032|M.vanbaalenii_PYR-1 IDWDSPEFAVTPDDERWILPDTDPFGGHPWYQSQPRQKQIEIGMWRQANV
Mb0909|M.bovis_AF2122/97 IDWESPEFAVTDNDPRWILPATDPLGRHPWYQAQSRERQIEIGMWRQANV
Rv0885|M.tuberculosis_H37Rv IDWESPEFAVTDNDPRWILPATDPLGRHPWYQAQSRERQIEIGMWRQANV
MLBr_02135|M.leprae_Br4923 IDWESPAFAVKDNDPRWILPDTDPLGRHPWYLAQPEQRKIEIGMWRQANV
MMAR_4564|M.marinum_M IDWDAP----LDPDKFYLPPRLVSLYGTEIWDEMTREQQIELSRQELVNT
MUL_4424|M.ulcerans_Agy99 IDWDAP----LDPDKFYLPPRLVSLYGTEMWDEMTREQQIELSRQELVNT
MAV_1064|M.avium_104 IDWDAP----LDPDKFFLPPRLVSLYGTPMWDEMTREQQIELSRQELVNT
MSMEG_5549|M.smegmatis_MC2_155 IEWDTP----LEPDKFFLPPKLVSLYGTPLWESMSREQQIELSRQELANT
Mflv_0937|M.gilvum_PYR-GCK IDWEAL----LADDKFFLPPQMSSLYGTDLWEQMSPQQRIDLSRHELANY
MAB_3921c|M.abscessus_ATCC_199 IDWDAP----PVPGLYWATPRRTSLYGTKLWDKLTQEQRIELTRHELGSI
*:*:: . : * .: : . :::*:: . .
TH_1805|M.thermoresistible__bu AKVGLQFELILIRGLTNYAFWVPN-GSPEYRYCLHETIEECNHTLMFQEM
Mvan_5032|M.vanbaalenii_PYR-1 AKVGLHFESILIRGLMNYAFWVPN-GSPEYRYCLHESVEECNHTMMFQEM
Mb0909|M.bovis_AF2122/97 AKVGLHFESILIRGLMNYTFWMPN-GSPEYRYCLHESVEECNHTMMFQEM
Rv0885|M.tuberculosis_H37Rv AKVGLHFESILIRGLMNYTFWMPN-GSPEYRYCLHESVEECNHTMMFQEM
MLBr_02135|M.leprae_Br4923 AKVGLHFESILVRGLMNYTFWMPN-GSPEYRYCLHECVEECNHTMMFQEM
MMAR_4564|M.marinum_M LSAGIWFENMLNQSLLRTILHEDP-TSRSTHYKLTELGDETRHMVMFGKA
MUL_4424|M.ulcerans_Agy99 LSAGIWFENMLNQSLLRTILHEDP-TSRSTHYKLTELGDETRHMVMFGKA
MAV_1064|M.avium_104 LSAGIWFENMLNQSLLRTILHEDP-TSRSTHYKLTELGDETRHMVMFGKA
MSMEG_5549|M.smegmatis_MC2_155 LSAGIWFENILNQALLRKMMHQDP-TARATHYELTELGDETRHMVMFGRA
Mflv_0937|M.gilvum_PYR-GCK LSMGIWFENMLNQSLLRGMIYSSP-TSNSTFYELTELGDEARHMLMFGKA
MAB_3921c|M.abscessus_ATCC_199 LSFGIYVETGLSAMLWRQVVEQNGGATDHGRYALTEVSEEARHSTMFGRL
. *: .* * * . . : * * * :* .* ** .
TH_1805|M.thermoresistible__bu VNRIGADVPGMPRVLRWLAPFIPQVAGPLPVPFFFGVLAGEEPIDHTQKN
Mvan_5032|M.vanbaalenii_PYR-1 VNRIGADVPGMPRLLKWLSQFIPLVAGPLPIPFFFGVLAGEEPIDHTQKN
Mb0909|M.bovis_AF2122/97 VNRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKN
Rv0885|M.tuberculosis_H37Rv VNRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKN
MLBr_02135|M.leprae_Br4923 VNRVGADVPGMPRRLRWLSPLVPLVAGPLPVAFFIGVLAGEEPIDHMQKN
MMAR_4564|M.marinum_M IERIGAKPVRPRRLHRMVINTLPLAFQ-RGSMLWVAALIGEEIFDSLQRQ
MUL_4424|M.ulcerans_Agy99 IERIGAKPVRPRRLHRMVINTLPLAFQ-RGSMLWVAALIGEEIFDSLQRQ
MAV_1064|M.avium_104 IERVGAKPVQPKRFHRYIINALPLAFQ-RGSMLWVAALIGEEIFDSLQRQ
MSMEG_5549|M.smegmatis_MC2_155 IERIGAKPVRPRLYQRMIINTLPFFF--RGSVLWVAALIGEEIFDSLQRQ
Mflv_0937|M.gilvum_PYR-GCK IRRIGVEPFWPKGRHARLVNAMPFLF--RGPMLWIAALVGEEIFDALQRR
MAB_3921c|M.abscessus_ATCC_199 VNKMGVEPYTYPKFATRVIRLLGLVP--LGPSGLGGLLLVEEVLDRAQRE
:.::*.. : : . * ** :* *:.
TH_1805|M.thermoresistible__bu VLREGKELHPIMERVMAIHVAEEARHISFAHEFLRKRLPRLNRRQRFWLS
Mvan_5032|M.vanbaalenii_PYR-1 VLREGRSLHPIMERVMAIHVAEEARHISFAHEYLRKRVPNLNRRQRFLLS
Mb0909|M.bovis_AF2122/97 VLREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWIS
Rv0885|M.tuberculosis_H37Rv VLREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWIS
MLBr_02135|M.leprae_Br4923 VLREGKSLHPIMERVMAIHVAEEARHISFAHEFLRKRLTHLTKRQLFWVS
MMAR_4564|M.marinum_M MMDDPE-LQPIIQRLMRIHVTEEARHIQFARDGARKRVGEMPRVNRWFMA
MUL_4424|M.ulcerans_Agy99 MMDDPE-LQPIIQRLMRIHVTEEARHIQFARDGARKRVGEMPRVNRWFMA
MAV_1064|M.avium_104 MMDDPE-LQPIIQRLMRIHVTEEARHIQFARDGARKRVAEMPRLNRWFMA
MSMEG_5549|M.smegmatis_MC2_155 MMDDPE-LQPFVQRVMRIHVTEEARHIQFARDGLRKRTSDMGWPTRVWVS
Mflv_0937|M.gilvum_PYR-GCK ILEDGENVQPLVHRLMRIHVTEEARHIQFARDGIRRDVGRLPSRTRWTLS
MAB_3921c|M.abscessus_ATCC_199 TMMDET-VQPHARQLMKIHVLEEARHITYAREELVRQIAERGPVSNAIHR
: : ::* .::* *** ****** :*:: :
TH_1805|M.thermoresistible__bu LNVPLIMRILCQAILVPPRSFFKEFDIPREVRRELFFRAPESRQMLRDMF
Mvan_5032|M.vanbaalenii_PYR-1 LNVPIIMRVLCQAIIVPPKSFWKEFDIPRSVKKEIFFGTPEARQFLRDMF
Mb0909|M.bovis_AF2122/97 LYFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMF
Rv0885|M.tuberculosis_H37Rv LYFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMF
MLBr_02135|M.leprae_Br4923 LYYPLTMRVLCNAIMVPPKAFWQEFNIPREVKKELFFRSPESRKLLRDIF
MMAR_4564|M.marinum_M NINGLGGYFFNYLFSNP--IPYARAGLDPKRARRIARSSPHRREIQIAGF
MUL_4424|M.ulcerans_Agy99 NINGLGGYFFNYLFSNP--IPYARAGLDPKRARRIARSSPHRREIQIAGF
MAV_1064|M.avium_104 NINGLGGYFFNYLFSNP--VPYARAGLDPKRARKTARTSAHRREIQIAGF
MSMEG_5549|M.smegmatis_MC2_155 NLNGLGGLFFRHLFSHP--IQYRRAGLDGRAGRRLARASAHRHEVQVAGF
Mflv_0937|M.gilvum_PYR-GCK NLHGLGAALYLKNFTRR--GLYQRVGLDGAEAQRQARANKHFHGMLTFGF
MAB_3921c|M.abscessus_ATCC_199 AIFALAVIGIYPVLFNP--KAYRAVGIHPLRGFFAFLTSPHYRENATWVS
: : : .: . :
TH_1805|M.thermoresistible__bu ADVRALCYDTGLMNP-VARLIWRLCKIDGPPSRYRSEPQRRHVVAAAA--
Mvan_5032|M.vanbaalenii_PYR-1 GDVRMLCHDTGLMNP-FAKLMWRICKIDGPPSRYRSEPARQHVVSAA---
Mb0909|M.bovis_AF2122/97 ADARMLAHDTGLMNP-IARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA-
Rv0885|M.tuberculosis_H37Rv ADARMLAHDTGLMNP-IARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA-
MLBr_02135|M.leprae_Br4923 ADVRMLAYDTRLMETRSARLMWHICKIDGQPSRYRGEPQRQHPATTSAA-
MMAR_4564|M.marinum_M APLATFLTEVGLLG-PIARRGWKRSRFL----------------------
MUL_4424|M.ulcerans_Agy99 ASLAIFLTEVGLLG-PIARRGWKRSRFL----------------------
MAV_1064|M.avium_104 APLAAFLTEVGLMG-PLARRGWKRSRFL----------------------
MSMEG_5549|M.smegmatis_MC2_155 APLAAFLEEVGLMG-RIGRRMWRRSGFLPQDHTPTVRHRGIAAGTEPAID
Mflv_0937|M.gilvum_PYR-GCK ASLAQFLEEARLMG-PVARRMWKRNHFL----------------------
MAB_3921c|M.abscessus_ATCC_199 EPLMRFMHEIGFLDGKFTGRLLRMSRAMPEDILAEIKAR-----------
: : :: :
TH_1805|M.thermoresistible__bu --------------------------------------------------
Mvan_5032|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0909|M.bovis_AF2122/97 --------------------------------------------------
Rv0885|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02135|M.leprae_Br4923 --------------------------------------------------
MMAR_4564|M.marinum_M --------------------------------------------------
MUL_4424|M.ulcerans_Agy99 --------------------------------------------------
MAV_1064|M.avium_104 --------------------------------------------------
MSMEG_5549|M.smegmatis_MC2_155 EDVYDGFAVLDNGDRDSRVRVRLTGHLDPIDGRYHWQGSILDADMVAGTG
Mflv_0937|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3921c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1805|M.thermoresistible__bu --------------------------------------
Mvan_5032|M.vanbaalenii_PYR-1 --------------------------------------
Mb0909|M.bovis_AF2122/97 --------------------------------------
Rv0885|M.tuberculosis_H37Rv --------------------------------------
MLBr_02135|M.leprae_Br4923 --------------------------------------
MMAR_4564|M.marinum_M --------------------------------------
MUL_4424|M.ulcerans_Agy99 --------------------------------------
MAV_1064|M.avium_104 --------------------------------------
MSMEG_5549|M.smegmatis_MC2_155 PVRLTIGQRSADARIVERTAQSTYTIAGVGEPPFTLAE
Mflv_0937|M.gilvum_PYR-GCK --------------------------------------
MAB_3921c|M.abscessus_ATCC_199 --------------------------------------