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SQTPSVEEDSPIERTAVRLLRSSVDRSYHPEVDVDWDAPDVPGLRYVPDRYISLYGTKIFERMTEEEKIR LGRLEASALASWGILAESALMHPMLKLASVSDPRSATAQYALTEVADECRHSVMFGRQINTLSDRSYNPP MIARALVGITALAPLSATIFSMMLMVEEILDRLQRQTMNDETLQPRTRAIAKIHVIEEARHISYARVALA RAVERTGRGRMALERLIVAAGAAVIPLIMVQPAVYRDAGLPPLRSAWTALRNPHYHANLRFFGERLVRVM NENDMLEGRLVQHLWRWSRMLPEDFVPQSKRTADA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1535c | - | - | 100% (316) | hypothetical protein MAB_1535c |
| M. abscessus ATCC 19977 | MAB_3921c | - | 2e-65 | 43.67% (300) | hypothetical protein MAB_3921c |
| M. abscessus ATCC 19977 | MAB_0051 | - | 4e-48 | 34.30% (309) | hypothetical protein MAB_0051 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0909 | - | 2e-17 | 26.91% (223) | hypothetical protein Mb0909 |
| M. gilvum PYR-GCK | Mflv_0937 | - | 1e-35 | 32.99% (288) | hypothetical protein Mflv_0937 |
| M. tuberculosis H37Rv | Rv0885 | - | 2e-17 | 26.91% (223) | hypothetical protein Rv0885 |
| M. leprae Br4923 | MLBr_02135 | - | 1e-17 | 24.41% (299) | putative transmembrane protein |
| M. marinum M | MMAR_4564 | - | 1e-42 | 36.21% (301) | hypothetical protein MMAR_4564 |
| M. avium 104 | MAV_1064 | - | 2e-41 | 35.86% (290) | hypothetical protein MAV_1064 |
| M. smegmatis MC2 155 | MSMEG_5549 | - | 5e-44 | 34.43% (305) | hypothetical protein MSMEG_5549 |
| M. thermoresistible (build 8) | TH_1805 | - | 1e-16 | 27.54% (207) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4424 | - | 4e-43 | 35.64% (303) | hypothetical protein MUL_4424 |
| M. vanbaalenii PYR-1 | Mvan_5032 | - | 6e-19 | 26.88% (279) | hypothetical protein Mvan_5032 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1805|M.thermoresistible__bu -----------------MEVTD---DAQYVDMLNTLSEGSVRRNFNPYID
Mvan_5032|M.vanbaalenii_PYR-1 MAVKEARTRIIRRWRRNMEIGDGPEDRAYVEKLATLSEGSVRRNFNPYTD
Mb0909|M.bovis_AF2122/97 ----MDRTRIVRRWRRNMDVAD---DAEYVEMLATLSEGSVRRNFNPYTD
Rv0885|M.tuberculosis_H37Rv ----MDRTRIVRRWRRNMDVAD---DAEYVEMLATLSEGSVRRNFNPYTD
MLBr_02135|M.leprae_Br4923 ----MARTRMVRRWRNNMEVRD---DTDYVGMLTTLSEGSVRRNFNPYTD
MMAR_4564|M.marinum_M -----------------MTTAVKPSGPGREEFSERLLRGSVKKSYEPIVD
MUL_4424|M.ulcerans_Agy99 -----------MKGRQAMTTAVKPSGPGREEFSERLLRGSVKKSYEPIVD
MAV_1064|M.avium_104 --MPSDQEDPTMTRAETIRSDARPTGPSREEFSERLLKGSVKKSYEPVVD
MSMEG_5549|M.smegmatis_MC2_155 -----------------MTTSVR-SAATRDEYAERLLKGSVKRSYAPVVD
Mflv_0937|M.gilvum_PYR-GCK ------------------MPAPSAITRDKDDVALRLLKGAAKKSYEPVVD
MAB_1535c|M.abscessus_ATCC_199 ----------------MSQTPSVEEDSPIERTAVRLLRSSVDRSYHPEVD
* ..:. :.: * *
TH_1805|M.thermoresistible__bu IDWDAPEFAVTPDDERWILPATDPLGRHPWYQAQPVKKQIEIGMWRQANV
Mvan_5032|M.vanbaalenii_PYR-1 IDWDSPEFAVTPDDERWILPDTDPFGGHPWYQSQPRQKQIEIGMWRQANV
Mb0909|M.bovis_AF2122/97 IDWESPEFAVTDNDPRWILPATDPLGRHPWYQAQSRERQIEIGMWRQANV
Rv0885|M.tuberculosis_H37Rv IDWESPEFAVTDNDPRWILPATDPLGRHPWYQAQSRERQIEIGMWRQANV
MLBr_02135|M.leprae_Br4923 IDWESPAFAVKDNDPRWILPDTDPLGRHPWYLAQPEQRKIEIGMWRQANV
MMAR_4564|M.marinum_M IDWDAP----LDPDKFYLPPRLVSLYGTEIWDEMTREQQIELSRQELVNT
MUL_4424|M.ulcerans_Agy99 IDWDAP----LDPDKFYLPPRLVSLYGTEMWDEMTREQQIELSRQELVNT
MAV_1064|M.avium_104 IDWDAP----LDPDKFFLPPRLVSLYGTPMWDEMTREQQIELSRQELVNT
MSMEG_5549|M.smegmatis_MC2_155 IEWDTP----LEPDKFFLPPKLVSLYGTPLWESMSREQQIELSRQELANT
Mflv_0937|M.gilvum_PYR-GCK IDWEAL----LADDKFFLPPQMSSLYGTDLWEQMSPQQRIDLSRHELANY
MAB_1535c|M.abscessus_ATCC_199 VDWDAP----DVPGLRYVPDRYISLYGTKIFERMTEEEKIRLGRLEASAL
::*:: . :: .: : . :.:* :. .
TH_1805|M.thermoresistible__bu AKVGLQFELILIRGLTNYAFWVPNGSPEYRYCLHETIEECNHTLMFQEMV
Mvan_5032|M.vanbaalenii_PYR-1 AKVGLHFESILIRGLMNYAFWVPNGSPEYRYCLHESVEECNHTMMFQEMV
Mb0909|M.bovis_AF2122/97 AKVGLHFESILIRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEMV
Rv0885|M.tuberculosis_H37Rv AKVGLHFESILIRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEMV
MLBr_02135|M.leprae_Br4923 AKVGLHFESILVRGLMNYTFWMPNGSPEYRYCLHECVEECNHTMMFQEMV
MMAR_4564|M.marinum_M LSAGIWFENMLNQSLLRTILHEDPTSRSTHYKLTELGDETRHMVMFGKAI
MUL_4424|M.ulcerans_Agy99 LSAGIWFENMLNQSLLRTILHEDPTSRSTHYKLTELGDETRHMVMFGKAI
MAV_1064|M.avium_104 LSAGIWFENMLNQSLLRTILHEDPTSRSTHYKLTELGDETRHMVMFGKAI
MSMEG_5549|M.smegmatis_MC2_155 LSAGIWFENILNQALLRKMMHQDPTARATHYELTELGDETRHMVMFGRAI
Mflv_0937|M.gilvum_PYR-GCK LSMGIWFENMLNQSLLRGMIYSSPTSNSTFYELTELGDEARHMLMFGKAI
MAB_1535c|M.abscessus_ATCC_199 ASWGILAESALMHPMLKLASVSDPRSATAQYALTEVADECRHSVMFGRQI
. *: * * : : . : * * * :* .* :** . :
TH_1805|M.thermoresistible__bu NRIGADVPGMPRVLRWLAPFIPQVAGPLPVPFFFGVLAGEEPIDHTQKNV
Mvan_5032|M.vanbaalenii_PYR-1 NRIGADVPGMPRLLKWLSQFIPLVAGPLPIPFFFGVLAGEEPIDHTQKNV
Mb0909|M.bovis_AF2122/97 NRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKNV
Rv0885|M.tuberculosis_H37Rv NRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKNV
MLBr_02135|M.leprae_Br4923 NRVGADVPGMPRRLRWLSPLVPLVAGPLPVAFFIGVLAGEEPIDHMQKNV
MMAR_4564|M.marinum_M ERIGAKPVRPRRLHRMVINTLPLAFQ-RGSMLWVAALIGEEIFDSLQRQM
MUL_4424|M.ulcerans_Agy99 ERIGAKPVRPRRLHRMVINTLPLAFQ-RGSMLWVAALIGEEIFDSLQRQM
MAV_1064|M.avium_104 ERVGAKPVQPKRFHRYIINALPLAFQ-RGSMLWVAALIGEEIFDSLQRQM
MSMEG_5549|M.smegmatis_MC2_155 ERIGAKPVRPRLYQRMIINTLPFFF--RGSVLWVAALIGEEIFDSLQRQM
Mflv_0937|M.gilvum_PYR-GCK RRIGVEPFWPKGRHARLVNAMPFLF--RGPMLWIAALVGEEIFDALQRRI
MAB_1535c|M.abscessus_ATCC_199 NTLSDRSYNPPMIARALVGITALAP--LSATIFSMMLMVEEILDRLQRQT
. :. : . :: * ** :* *:.
TH_1805|M.thermoresistible__bu LREGKELHPIMERVMAIHVAEEARHISFAHEFLRKRLPRLNRRQRFWLSL
Mvan_5032|M.vanbaalenii_PYR-1 LREGRSLHPIMERVMAIHVAEEARHISFAHEYLRKRVPNLNRRQRFLLSL
Mb0909|M.bovis_AF2122/97 LREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWISL
Rv0885|M.tuberculosis_H37Rv LREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWISL
MLBr_02135|M.leprae_Br4923 LREGKSLHPIMERVMAIHVAEEARHISFAHEFLRKRLTHLTKRQLFWVSL
MMAR_4564|M.marinum_M MDDPE-LQPIIQRLMRIHVTEEARHIQFARDGARKRVGEMPRVNRWFMAN
MUL_4424|M.ulcerans_Agy99 MDDPE-LQPIIQRLMRIHVTEEARHIQFARDGARKRVGEMPRVNRWFMAN
MAV_1064|M.avium_104 MDDPE-LQPIIQRLMRIHVTEEARHIQFARDGARKRVAEMPRLNRWFMAN
MSMEG_5549|M.smegmatis_MC2_155 MDDPE-LQPFVQRVMRIHVTEEARHIQFARDGLRKRTSDMGWPTRVWVSN
Mflv_0937|M.gilvum_PYR-GCK LEDGENVQPLVHRLMRIHVTEEARHIQFARDGIRRDVGRLPSRTRWTLSN
MAB_1535c|M.abscessus_ATCC_199 MNDET-LQPRTRAIAKIHVIEEARHISYARVALARAVERTGRGRMALERL
: : ::* . : *** ******.:*: :
TH_1805|M.thermoresistible__bu NVPLIMRILCQAILVPPRSFFKEFDIPREVRRELFFRAPESRQMLRDMFA
Mvan_5032|M.vanbaalenii_PYR-1 NVPIIMRVLCQAIIVPPKSFWKEFDIPRSVKKEIFFGTPEARQFLRDMFG
Mb0909|M.bovis_AF2122/97 YFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMFA
Rv0885|M.tuberculosis_H37Rv YFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMFA
MLBr_02135|M.leprae_Br4923 YYPLTMRVLCNAIMVPPKAFWQEFNIPREVKKELFFRSPESRKLLRDIFA
MMAR_4564|M.marinum_M INGLGGYFFNYLFSNP--IPYARAGLDPKRARRIARSSPHRREIQIAGFA
MUL_4424|M.ulcerans_Agy99 INGLGGYFFNYLFSNP--IPYARAGLDPKRARRIARSSPHRREIQIAGFA
MAV_1064|M.avium_104 INGLGGYFFNYLFSNP--VPYARAGLDPKRARKTARTSAHRREIQIAGFA
MSMEG_5549|M.smegmatis_MC2_155 LNGLGGLFFRHLFSHP--IQYRRAGLDGRAGRRLARASAHRHEVQVAGFA
Mflv_0937|M.gilvum_PYR-GCK LHGLGAALYLKNFTRR--GLYQRVGLDGAEAQRQARANKHFHGMLTFGFA
MAB_1535c|M.abscessus_ATCC_199 IVAAGAAVIPLIMVQP--AVYRDAGLPPLRSAWTALRNPHYHANLRFFGE
: : .: . :
TH_1805|M.thermoresistible__bu DVRALCYDTGLMNP-VARLIWRLCKIDGPPSRYRSEPQRRHVVAAAA---
Mvan_5032|M.vanbaalenii_PYR-1 DVRMLCHDTGLMNP-FAKLMWRICKIDGPPSRYRSEPARQHVVSAA----
Mb0909|M.bovis_AF2122/97 DARMLAHDTGLMNP-IARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA--
Rv0885|M.tuberculosis_H37Rv DARMLAHDTGLMNP-IARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA--
MLBr_02135|M.leprae_Br4923 DVRMLAYDTRLMETRSARLMWHICKIDGQPSRYRGEPQRQHPATTSAA--
MMAR_4564|M.marinum_M PLATFLTEVGLLG-PIARRGWKRSRFL-----------------------
MUL_4424|M.ulcerans_Agy99 SLAIFLTEVGLLG-PIARRGWKRSRFL-----------------------
MAV_1064|M.avium_104 PLAAFLTEVGLMG-PLARRGWKRSRFL-----------------------
MSMEG_5549|M.smegmatis_MC2_155 PLAAFLEEVGLMG-RIGRRMWRRSGFLPQDHTPTVRHRGIAAGTEPAIDE
Mflv_0937|M.gilvum_PYR-GCK SLAQFLEEARLMG-PVARRMWKRNHFL-----------------------
MAB_1535c|M.abscessus_ATCC_199 RLVRVMNENDMLEGRLVQHLWRWSRMLPEDFVPQSKRTADA---------
. : :: : *: :
TH_1805|M.thermoresistible__bu --------------------------------------------------
Mvan_5032|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0909|M.bovis_AF2122/97 --------------------------------------------------
Rv0885|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02135|M.leprae_Br4923 --------------------------------------------------
MMAR_4564|M.marinum_M --------------------------------------------------
MUL_4424|M.ulcerans_Agy99 --------------------------------------------------
MAV_1064|M.avium_104 --------------------------------------------------
MSMEG_5549|M.smegmatis_MC2_155 DVYDGFAVLDNGDRDSRVRVRLTGHLDPIDGRYHWQGSILDADMVAGTGP
Mflv_0937|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1535c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1805|M.thermoresistible__bu -------------------------------------
Mvan_5032|M.vanbaalenii_PYR-1 -------------------------------------
Mb0909|M.bovis_AF2122/97 -------------------------------------
Rv0885|M.tuberculosis_H37Rv -------------------------------------
MLBr_02135|M.leprae_Br4923 -------------------------------------
MMAR_4564|M.marinum_M -------------------------------------
MUL_4424|M.ulcerans_Agy99 -------------------------------------
MAV_1064|M.avium_104 -------------------------------------
MSMEG_5549|M.smegmatis_MC2_155 VRLTIGQRSADARIVERTAQSTYTIAGVGEPPFTLAE
Mflv_0937|M.gilvum_PYR-GCK -------------------------------------
MAB_1535c|M.abscessus_ATCC_199 -------------------------------------