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MKGRQAMTTAVKPSGPGREEFSERLLRGSVKKSYEPIVDIDWDAPLDPDKFYLPPRLVSLYGTEMWDEMT REQQIELSRQELVNTLSAGIWFENMLNQSLLRTILHEDPTSRSTHYKLTELGDETRHMVMFGKAIERIGA KPVRPRRLHRMVINTLPLAFQRGSMLWVAALIGEEIFDSLQRQMMDDPELQPIIQRLMRIHVTEEARHIQ FARDGARKRVGEMPRVNRWFMANINGLGGYFFNYLFSNPIPYARAGLDPKRARRIARSSPHRREIQIAGF ASLAIFLTEVGLLGPIARRGWKRSRFL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4424 | - | - | 100% (307) | hypothetical protein MUL_4424 |
| M. ulcerans Agy99 | MUL_0265 | - | 9e-24 | 30.22% (225) | hypothetical protein MUL_0265 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0909 | - | 7e-29 | 30.30% (297) | hypothetical protein Mb0909 |
| M. gilvum PYR-GCK | Mflv_0937 | - | 1e-95 | 57.39% (291) | hypothetical protein Mflv_0937 |
| M. tuberculosis H37Rv | Rv0885 | - | 7e-29 | 30.30% (297) | hypothetical protein Rv0885 |
| M. leprae Br4923 | MLBr_02135 | - | 8e-24 | 31.92% (213) | putative transmembrane protein |
| M. abscessus ATCC 19977 | MAB_1035c | - | 1e-100 | 59.59% (292) | hypothetical protein MAB_1035c |
| M. marinum M | MMAR_4564 | - | 1e-174 | 99.00% (301) | hypothetical protein MMAR_4564 |
| M. avium 104 | MAV_1064 | - | 1e-162 | 88.60% (307) | hypothetical protein MAV_1064 |
| M. smegmatis MC2 155 | MSMEG_5549 | - | 1e-127 | 72.09% (301) | hypothetical protein MSMEG_5549 |
| M. thermoresistible (build 8) | TH_1805 | - | 2e-27 | 31.31% (297) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_5032 | - | 1e-26 | 29.32% (307) | hypothetical protein Mvan_5032 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4424|M.ulcerans_Agy99 -----------MKGRQAMTTAVKPSGPGREEFSERLLRGSVKKSYEPIVD
MMAR_4564|M.marinum_M -----------------MTTAVKPSGPGREEFSERLLRGSVKKSYEPIVD
MAV_1064|M.avium_104 --MPSDQEDPTMTRAETIRSDARPTGPSREEFSERLLKGSVKKSYEPVVD
MSMEG_5549|M.smegmatis_MC2_155 -----------------MTTSVR-SAATRDEYAERLLKGSVKRSYAPVVD
MAB_1035c|M.abscessus_ATCC_199 --------------MTATLNNGPARTPNREEYSDRLLKGTVRRSYQPMVD
Mflv_0937|M.gilvum_PYR-GCK ------------------MPAPSAITRDKDDVALRLLKGAAKKSYEPVVD
Mb0909|M.bovis_AF2122/97 ----MDRTRIVRRWRRNMDVAD---DAEYVEMLATLSEGSVRRNFNPYTD
Rv0885|M.tuberculosis_H37Rv ----MDRTRIVRRWRRNMDVAD---DAEYVEMLATLSEGSVRRNFNPYTD
MLBr_02135|M.leprae_Br4923 ----MARTRMVRRWRNNMEVRD---DTDYVGMLTTLSEGSVRRNFNPYTD
TH_1805|M.thermoresistible__bu -----------------MEVTD---DAQYVDMLNTLSEGSVRRNFNPYID
Mvan_5032|M.vanbaalenii_PYR-1 MAVKEARTRIIRRWRRNMEIGDGPEDRAYVEKLATLSEGSVRRNFNPYTD
* .*:.::.: * *
MUL_4424|M.ulcerans_Agy99 IDWDAP----LDPDKFYLPPRLVSLYGTEMWDEMTREQQIELSRQELVNT
MMAR_4564|M.marinum_M IDWDAP----LDPDKFYLPPRLVSLYGTEIWDEMTREQQIELSRQELVNT
MAV_1064|M.avium_104 IDWDAP----LDPDKFFLPPRLVSLYGTPMWDEMTREQQIELSRQELVNT
MSMEG_5549|M.smegmatis_MC2_155 IEWDTP----LEPDKFFLPPKLVSLYGTPLWESMSREQQIELSRQELANT
MAB_1035c|M.abscessus_ATCC_199 LDWDAP----LDPDKYYLPPKVVSLYGTEVWNRMSRAEQIELSRHEMVNL
Mflv_0937|M.gilvum_PYR-GCK IDWEAL----LADDKFFLPPQMSSLYGTDLWEQMSPQQRIDLSRHELANY
Mb0909|M.bovis_AF2122/97 IDWESPEFAVTDNDPRWILPATDPLGRHPWYQAQSRERQIEIGMWRQANV
Rv0885|M.tuberculosis_H37Rv IDWESPEFAVTDNDPRWILPATDPLGRHPWYQAQSRERQIEIGMWRQANV
MLBr_02135|M.leprae_Br4923 IDWESPAFAVKDNDPRWILPDTDPLGRHPWYLAQPEQRKIEIGMWRQANV
TH_1805|M.thermoresistible__bu IDWDAPEFAVTPDDERWILPATDPLGRHPWYQAQPVKKQIEIGMWRQANV
Mvan_5032|M.vanbaalenii_PYR-1 IDWDSPEFAVTPDDERWILPDTDPFGGHPWYQSQPRQKQIEIGMWRQANV
::*:: * :: * .: : . .:*::. . .*
MUL_4424|M.ulcerans_Agy99 LSAGIWFENMLNQSLLRTILHEDPTSRSTHYKLTELGDETRHMVMFGKAI
MMAR_4564|M.marinum_M LSAGIWFENMLNQSLLRTILHEDPTSRSTHYKLTELGDETRHMVMFGKAI
MAV_1064|M.avium_104 LSAGIWFENMLNQSLLRTILHEDPTSRSTHYKLTELGDETRHMVMFGKAI
MSMEG_5549|M.smegmatis_MC2_155 LSAGIWFENILNQALLRKMMHQDPTARATHYELTELGDETRHMVMFGRAI
MAB_1035c|M.abscessus_ATCC_199 LSTGIWFENMLNQGLLRVMMHANPVSSETLYSLAEIGDETRHMTMFAKAI
Mflv_0937|M.gilvum_PYR-GCK LSMGIWFENMLNQSLLRGMIYSSPTSNSTFYELTELGDEARHMLMFGKAI
Mb0909|M.bovis_AF2122/97 AKVGLHFESILIRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEMV
Rv0885|M.tuberculosis_H37Rv AKVGLHFESILIRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEMV
MLBr_02135|M.leprae_Br4923 AKVGLHFESILVRGLMNYTFWMPNGSPEYRYCLHECVEECNHTMMFQEMV
TH_1805|M.thermoresistible__bu AKVGLQFELILIRGLTNYAFWVPNGSPEYRYCLHETIEECNHTLMFQEMV
Mvan_5032|M.vanbaalenii_PYR-1 AKVGLHFESILIRGLMNYAFWVPNGSPEYRYCLHESVEECNHTMMFQEMV
. *: ** :* :.* . : : * * * :* .* ** . :
MUL_4424|M.ulcerans_Agy99 ERIGAKPVRPRRLHRMVINTLPLAFQ-RGSMLWVAALIGEEIFDSLQRQM
MMAR_4564|M.marinum_M ERIGAKPVRPRRLHRMVINTLPLAFQ-RGSMLWVAALIGEEIFDSLQRQM
MAV_1064|M.avium_104 ERVGAKPVQPKRFHRYIINALPLAFQ-RGSMLWVAALIGEEIFDSLQRQM
MSMEG_5549|M.smegmatis_MC2_155 ERIGAKPVRPRLYQRMIINTLPFFF--RGSVLWVAALIGEEIFDSLQRQM
MAB_1035c|M.abscessus_ATCC_199 EKTGLPPYRMPWYQRVMANLLPLAL--KGPVLWVAALIGEEIFDALQREI
Mflv_0937|M.gilvum_PYR-GCK RRIGVEPFWPKGRHARLVNAMPFLF--RGPMLWIAALVGEEIFDALQRRI
Mb0909|M.bovis_AF2122/97 NRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKNV
Rv0885|M.tuberculosis_H37Rv NRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKNV
MLBr_02135|M.leprae_Br4923 NRVGADVPGMPRRLRWLSPLVPLVAGPLPVAFFIGVLAGEEPIDHMQKNV
TH_1805|M.thermoresistible__bu NRIGADVPGMPRVLRWLAPFIPQVAGPLPVPFFFGVLAGEEPIDHTQKNV
Mvan_5032|M.vanbaalenii_PYR-1 NRIGADVPGMPRLLKWLSQFIPLVAGPLPIPFFFGVLAGEEPIDHTQKNV
.: * : :* ::...* *** :* *:.:
MUL_4424|M.ulcerans_Agy99 MDDPE-LQPIIQRLMRIHVTEEARHIQFARDGARKRVGEMPRVNRWFMAN
MMAR_4564|M.marinum_M MDDPE-LQPIIQRLMRIHVTEEARHIQFARDGARKRVGEMPRVNRWFMAN
MAV_1064|M.avium_104 MDDPE-LQPIIQRLMRIHVTEEARHIQFARDGARKRVAEMPRLNRWFMAN
MSMEG_5549|M.smegmatis_MC2_155 MDDPE-LQPFVQRVMRIHVTEEARHIQFARDGLRKRTSDMGWPTRVWVSN
MAB_1035c|M.abscessus_ATCC_199 MDDPE-LQPLVQRLMRIHVTEEARHIQFARDGIRQRLDRTPTRVKVILRL
Mflv_0937|M.gilvum_PYR-GCK LEDGENVQPLVHRLMRIHVTEEARHIQFARDGIRRDVGRLPSRTRWTLSN
Mb0909|M.bovis_AF2122/97 LREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWISL
Rv0885|M.tuberculosis_H37Rv LREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWISL
MLBr_02135|M.leprae_Br4923 LREGKSLHPIMERVMAIHVAEEARHISFAHEFLRKRLTHLTKRQLFWVSL
TH_1805|M.thermoresistible__bu LREGKELHPIMERVMAIHVAEEARHISFAHEFLRKRLPRLNRRQRFWLSL
Mvan_5032|M.vanbaalenii_PYR-1 LREGRSLHPIMERVMAIHVAEEARHISFAHEYLRKRVPNLNRRQRFLLSL
: : . ::*::.*:* ***:******.**:: *: :
MUL_4424|M.ulcerans_Agy99 INGLGGYFFNYLFSNP--IPYARAGLDPKRARRIARSSPHRREIQIAGFA
MMAR_4564|M.marinum_M INGLGGYFFNYLFSNP--IPYARAGLDPKRARRIARSSPHRREIQIAGFA
MAV_1064|M.avium_104 INGLGGYFFNYLFSNP--VPYARAGLDPKRARKTARTSAHRREIQIAGFA
MSMEG_5549|M.smegmatis_MC2_155 LNGLGGLFFRHLFSHP--IQYRRAGLDGRAGRRLARASAHRHEVQVAGFA
MAB_1035c|M.abscessus_ATCC_199 TNGLGGPIFRYLLTNK--KMYEAVGLPGRETMRLARSNPAFQEASQTGFA
Mflv_0937|M.gilvum_PYR-GCK LHGLGAALYLKNFTRR--GLYQRVGLDGAEAQRQARANKHFHGMLTFGFA
Mb0909|M.bovis_AF2122/97 YFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMFA
Rv0885|M.tuberculosis_H37Rv YFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMFA
MLBr_02135|M.leprae_Br4923 YYPLTMRVLCNAIMVPPKAFWQEFNIPREVKKELFFRSPESRKLLRDIFA
TH_1805|M.thermoresistible__bu NVPLIMRILCQAILVPPRSFFKEFDIPREVRRELFFRAPESRQMLRDMFA
Mvan_5032|M.vanbaalenii_PYR-1 NVPIIMRVLCQAIIVPPKSFWKEFDIPRSVKKEIFFGTPEARQFLRDMFG
: : : .: . : *.
MUL_4424|M.ulcerans_Agy99 SLAIFLTEVGLLGP-IARRGWKRSRFL-----------------------
MMAR_4564|M.marinum_M PLATFLTEVGLLGP-IARRGWKRSRFL-----------------------
MAV_1064|M.avium_104 PLAAFLTEVGLMGP-LARRGWKRSRFL-----------------------
MSMEG_5549|M.smegmatis_MC2_155 PLAAFLEEVGLMGR-IGRRMWRRSGFLPQDHTPTVRHRGIAAGTEPAIDE
MAB_1035c|M.abscessus_ATCC_199 PLYKFLEETGLMGR-LSRRMWRRTGFVA----------------------
Mflv_0937|M.gilvum_PYR-GCK SLAQFLEEARLMGP-VARRMWKRNHFL-----------------------
Mb0909|M.bovis_AF2122/97 DARMLAHDTGLMNP-IARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA--
Rv0885|M.tuberculosis_H37Rv DARMLAHDTGLMNP-IARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA--
MLBr_02135|M.leprae_Br4923 DVRMLAYDTRLMETRSARLMWHICKIDGQPSRYRGEPQRQHPATTSAA--
TH_1805|M.thermoresistible__bu DVRALCYDTGLMNP-VARLIWRLCKIDGPPSRYRSEPQRRHVVAAAA---
Mvan_5032|M.vanbaalenii_PYR-1 DVRMLCHDTGLMNP-FAKLMWRICKIDGPPSRYRSEPARQHVVSAA----
: :. *: .: *: :
MUL_4424|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4564|M.marinum_M --------------------------------------------------
MAV_1064|M.avium_104 --------------------------------------------------
MSMEG_5549|M.smegmatis_MC2_155 DVYDGFAVLDNGDRDSRVRVRLTGHLDPIDGRYHWQGSILDADMVAGTGP
MAB_1035c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0937|M.gilvum_PYR-GCK --------------------------------------------------
Mb0909|M.bovis_AF2122/97 --------------------------------------------------
Rv0885|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02135|M.leprae_Br4923 --------------------------------------------------
TH_1805|M.thermoresistible__bu --------------------------------------------------
Mvan_5032|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4424|M.ulcerans_Agy99 -------------------------------------
MMAR_4564|M.marinum_M -------------------------------------
MAV_1064|M.avium_104 -------------------------------------
MSMEG_5549|M.smegmatis_MC2_155 VRLTIGQRSADARIVERTAQSTYTIAGVGEPPFTLAE
MAB_1035c|M.abscessus_ATCC_199 -------------------------------------
Mflv_0937|M.gilvum_PYR-GCK -------------------------------------
Mb0909|M.bovis_AF2122/97 -------------------------------------
Rv0885|M.tuberculosis_H37Rv -------------------------------------
MLBr_02135|M.leprae_Br4923 -------------------------------------
TH_1805|M.thermoresistible__bu -------------------------------------
Mvan_5032|M.vanbaalenii_PYR-1 -------------------------------------