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M. leprae Br4923 MLBr_02135 (-)

annotation: putative transmembrane protein
coordinates: 2537421 - 2538446
length: 341

ARTRMVRRWRNNMEVRDDTDYVGMLTTLSEGSVRRNFNPYTDIDWESPAFAVKDNDPRWILPDTDPLGRH
PWYLAQPEQRKIEIGMWRQANVAKVGLHFESILVRGLMNYTFWMPNGSPEYRYCLHECVEECNHTMMFQE
MVNRVGADVPGMPRRLRWLSPLVPLVAGPLPVAFFIGVLAGEEPIDHMQKNVLREGKSLHPIMERVMAIH
VAEEARHISFAHEFLRKRLTHLTKRQLFWVSLYYPLTMRVLCNAIMVPPKAFWQEFNIPREVKKELFFRS
PESRKLLRDIFADVRMLAYDTRLMETRSARLMWHICKIDGQPSRYRGEPQRQHPATTSAA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02135--100% (341)putative transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0909-1e-17383.87% (341) hypothetical protein Mb0909
M. gilvum PYR-GCKMflv_1719-1e-15876.04% (338) hypothetical protein Mflv_1719
M. tuberculosis H37RvRv0885-1e-17383.87% (341) hypothetical protein Rv0885
M. abscessus ATCC 19977MAB_0929-1e-12062.85% (323) hypothetical protein MAB_0929
M. marinum MMMAR_4647-0.088.27% (341) hypothetical protein MMAR_4647
M. avium 104MAV_1013-1e-17987.20% (336) hypothetical protein MAV_1013
M. smegmatis MC2 155MSMEG_5682-1e-15175.70% (321) hypothetical protein MSMEG_5682
M. thermoresistible (build 8)TH_1805-1e-15275.84% (327) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0265-1e-18087.98% (341) hypothetical protein MUL_0265
M. vanbaalenii PYR-1Mvan_5032-1e-15676.19% (336) hypothetical protein Mvan_5032

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1719|M.gilvum_PYR-GCK          MAVKEARTRMIRRWRKNMDVTD---DAQYVETLTALSEGSVRRNFNPYTD
Mvan_5032|M.vanbaalenii_PYR-1       MAVKEARTRIIRRWRRNMEIGDGPEDRAYVEKLATLSEGSVRRNFNPYTD
Mb0909|M.bovis_AF2122/97            ----MDRTRIVRRWRRNMDVAD---DAEYVEMLATLSEGSVRRNFNPYTD
Rv0885|M.tuberculosis_H37Rv         ----MDRTRIVRRWRRNMDVAD---DAEYVEMLATLSEGSVRRNFNPYTD
MMAR_4647|M.marinum_M               ----MARTRMVRRWRRNMEVRD---DAEYVEMLATLSEGSVRRNFNPYTD
MUL_0265|M.ulcerans_Agy99           ----MARTRMVRRWRRNMEVRD---DAEYVEMLATLSEGSVRRNFNPYTD
MLBr_02135|M.leprae_Br4923          ----MARTRMVRRWRNNMEVRD---DTDYVGMLTTLSEGSVRRNFNPYTD
MAV_1013|M.avium_104                ---------MVRRWRRNMEVRD---DTDYVNMLATLSEGSVRRNFNPYTD
TH_1805|M.thermoresistible__bu      -----------------MEVTD---DAQYVDMLNTLSEGSVRRNFNPYID
MSMEG_5682|M.smegmatis_MC2_155      -----------------MDVSD---DTQYVDMLTTLSEGSVRRNFNPYQD
MAB_0929|M.abscessus_ATCC_1997      -------MSLREKLRAKKEVRG---DAKYVQVLETLSHGSTNRNFDPFID
                                                      :: .   *  **  * :**.**..***:*: *

Mflv_1719|M.gilvum_PYR-GCK          IDWDSPEFAVVPNDERWILPG-TDPIGQHPWYRAQPLERQIEIGMWRQAN
Mvan_5032|M.vanbaalenii_PYR-1       IDWDSPEFAVTPDDERWILPD-TDPFGGHPWYQSQPRQKQIEIGMWRQAN
Mb0909|M.bovis_AF2122/97            IDWESPEFAVTDNDPRWILPA-TDPLGRHPWYQAQSRERQIEIGMWRQAN
Rv0885|M.tuberculosis_H37Rv         IDWESPEFAVTDNDPRWILPA-TDPLGRHPWYQAQSRERQIEIGMWRQAN
MMAR_4647|M.marinum_M               IDWESPEFAVTDNDPRWILPA-TDPLGRHPWYQAQSEERKIKIGMWRQAN
MUL_0265|M.ulcerans_Agy99           IDWESPEFAVTDNDPRWILPA-TDPLGRHPWYQAQSEERKIKIGMWRQAN
MLBr_02135|M.leprae_Br4923          IDWESPAFAVKDNDPRWILPD-TDPLGRHPWYLAQPEQRKIEIGMWRQAN
MAV_1013|M.avium_104                IDWDSPEFAVTEDDPRWILPA-TDPLGRHPWYLAQSDERKIKIGMWRQAN
TH_1805|M.thermoresistible__bu      IDWDAPEFAVTPDDERWILPA-TDPLGRHPWYQAQPVKKQIEIGMWRQAN
MSMEG_5682|M.smegmatis_MC2_155      IDWDSPEFAVIPNDTRWVLTD-TDPLGRHPWYRAQSLERQIEIGMWRQAN
MAB_0929|M.abscessus_ATCC_1997      IDWDSPEYAVVPNDTRWVLPHRTDPLGRHPWYQSQPLEKQIEIGMWRQAN
                                    ***::* :**  :* **:*.  ***:* **** :*. :::*:********

Mflv_1719|M.gilvum_PYR-GCK          VAKVGLHFESILIRGLMNYAFWVPNGSPEYRYCLHESVEECNHTLMFQEM
Mvan_5032|M.vanbaalenii_PYR-1       VAKVGLHFESILIRGLMNYAFWVPNGSPEYRYCLHESVEECNHTMMFQEM
Mb0909|M.bovis_AF2122/97            VAKVGLHFESILIRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEM
Rv0885|M.tuberculosis_H37Rv         VAKVGLHFESILIRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEM
MMAR_4647|M.marinum_M               VAKVGLHFESILVRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEM
MUL_0265|M.ulcerans_Agy99           VAKVGLHFESILVRGLMNYTFWMPNGSPEYRYCLHESVEECNHTMMFQEM
MLBr_02135|M.leprae_Br4923          VAKVGLHFESILVRGLMNYTFWMPNGSPEYRYCLHECVEECNHTMMFQEM
MAV_1013|M.avium_104                VAKVGLHFESILIRGLMNYTFWVPNGSPEYRYCLHESVEECNHTMMFQEM
TH_1805|M.thermoresistible__bu      VAKVGLQFELILIRGLTNYAFWVPNGSPEYRYCLHETIEECNHTLMFQEM
MSMEG_5682|M.smegmatis_MC2_155      VAKVGLHFENILIRGLMEYSFWVPNGSPEYRYCLHEAVEECNHTLMFQEM
MAB_0929|M.abscessus_ATCC_1997      VAKVGLHFESILIRGLIQYAFSVPNGSPEFRYLNHESIEECNHTLMFQEM
                                    ******:** **:*** :*:* :******:**  ** :******:*****

Mflv_1719|M.gilvum_PYR-GCK          VNRIGADVPGMPRVLKWLSQFIPLAAGPLPIPFFFGVLAGEEPIDHTQKN
Mvan_5032|M.vanbaalenii_PYR-1       VNRIGADVPGMPRLLKWLSQFIPLVAGPLPIPFFFGVLAGEEPIDHTQKN
Mb0909|M.bovis_AF2122/97            VNRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKN
Rv0885|M.tuberculosis_H37Rv         VNRVGADVPGLPRRLRWVSPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKN
MMAR_4647|M.marinum_M               VNRVGADVPGMPRRLRWISPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKN
MUL_0265|M.ulcerans_Agy99           VNRVGADVLGMPRRLRWISPLVPLVAGPLPVAFFIGVLAGEEPIDHTQKN
MLBr_02135|M.leprae_Br4923          VNRVGADVPGMPRRLRWLSPLVPLVAGPLPVAFFIGVLAGEEPIDHMQKN
MAV_1013|M.avium_104                VNRVGADVPGMPRLLKWISPLIPLVAGPLPVAFFIGVLAGEEPIDHTQKN
TH_1805|M.thermoresistible__bu      VNRIGADVPGMPRVLRWLAPFIPQVAGPLPVPFFFGVLAGEEPIDHTQKN
MSMEG_5682|M.smegmatis_MC2_155      VNRIGKDVPGMPRLLRWLQPVIPLAAGPTPIPFFFGVLAGEEPIDHTQKS
MAB_0929|M.abscessus_ATCC_1997      VNRLGVDVPGMPRLLRWLSPFIPLASTVAPETFFIGVLAGEEPIDHTQKN
                                    ***:* ** *:** *:*:  .:* .:   * .**:*********** **.

Mflv_1719|M.gilvum_PYR-GCK          VLREGKSLHPIMERVMAIHVAEEARHISFAHEYLRKRVPHLNRRQKFLLS
Mvan_5032|M.vanbaalenii_PYR-1       VLREGRSLHPIMERVMAIHVAEEARHISFAHEYLRKRVPNLNRRQRFLLS
Mb0909|M.bovis_AF2122/97            VLREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWIS
Rv0885|M.tuberculosis_H37Rv         VLREGKSLHPIMERVMSIHVAEEARHISFAHEYLRKRLPRLTRMQRFWIS
MMAR_4647|M.marinum_M               VLREGKLLHPVMERVMAIHVAEEARHISFAHEFLRKRLPKLTKRQRFWIS
MUL_0265|M.ulcerans_Agy99           VLREGKLLHPVMERVMAIHVAEEARHISFAHEFLRKRLPKLTKRQRFWIS
MLBr_02135|M.leprae_Br4923          VLREGKSLHPIMERVMAIHVAEEARHISFAHEFLRKRLTHLTKRQLFWVS
MAV_1013|M.avium_104                VLREGKSLHPIMERVMAIHVAEEARHISFAHEFLRKRLPHLTKRQRFWVS
TH_1805|M.thermoresistible__bu      VLREGKELHPIMERVMAIHVAEEARHISFAHEFLRKRLPRLNRRQRFWLS
MSMEG_5682|M.smegmatis_MC2_155      VLREGRKLHPIMERVMAIHVAEEARHISFAHQYLHKRVPRLRRRQRFMLS
MAB_0929|M.abscessus_ATCC_1997      VLREGDNLHPIMRRVMEIHVAEEARHISFAHEYLHKRVPTMHWFNRFVLS
                                    *****  ***:*.*** **************::*:**:. :   : * :*

Mflv_1719|M.gilvum_PYR-GCK          LNVPIIMRVLCQAIIVPPKSFWKEFDIPRSVKKEIFFGTPEARQFLRDMF
Mvan_5032|M.vanbaalenii_PYR-1       LNVPIIMRVLCQAIIVPPKSFWKEFDIPRSVKKEIFFGTPEARQFLRDMF
Mb0909|M.bovis_AF2122/97            LYFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMF
Rv0885|M.tuberculosis_H37Rv         LYFPLTMRSLCNAIVVPPKAFWEEFDIPREVKKELFFGSPESRKWLCDMF
MMAR_4647|M.marinum_M               LYLPLTMRSLANAILVPPKEFWAEFDIPREVKKELFFRSPESRKWLRDMF
MUL_0265|M.ulcerans_Agy99           LYLPLTMRSLANAILVPPKEFWAEFDIPREVKKELFFRSPESRKWLRDMF
MLBr_02135|M.leprae_Br4923          LYYPLTMRVLCNAIMVPPKAFWQEFNIPREVKKELFFRSPESRKLLRDIF
MAV_1013|M.avium_104                LYYPLTMRLLCNAITVPPKQFWREFDIPREVKKELFFRSPESRKWLSDMF
TH_1805|M.thermoresistible__bu      LNVPLIMRILCQAILVPPRSFFKEFDIPREVRRELFFRAPESRQMLRDMF
MSMEG_5682|M.smegmatis_MC2_155      LYVPLVMRILCSAILVPPRPFWKEFDIPRSVRKEVFFRAPESRKMLRDMF
MAB_0929|M.abscessus_ATCC_1997      ISTPIIMRVLMGAIMTPPRSFFKKFGIPDDVRKEIFWKSPASRQTMSEVF
                                    :  *: ** *  ** .**: *: :*.** .*::*:*: :* :*: : ::*

Mflv_1719|M.gilvum_PYR-GCK          GDVRMLCHDTGLMNP-VAKLMWRICRIDGPPSRYRSEPARGHVVTAA---
Mvan_5032|M.vanbaalenii_PYR-1       GDVRMLCHDTGLMNP-FAKLMWRICKIDGPPSRYRSEPARQHVVSAA---
Mb0909|M.bovis_AF2122/97            ADARMLAHDTGLMNP-IARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA-
Rv0885|M.tuberculosis_H37Rv         ADARMLAHDTGLMNP-IARLVWRLCKIDGKPSRYRSEPQRQHLAAAPAA-
MMAR_4647|M.marinum_M               ADVRMLAHDTGLMQTRSARLMWRICKIDGEPSRYRSEPQRQHLAASPAA-
MUL_0265|M.ulcerans_Agy99           ADVRMLAHDTGLMQTRSARLMWRICKIDGEPSRYRSEPQRQHLAASPAA-
MLBr_02135|M.leprae_Br4923          ADVRMLAYDTRLMETRSARLMWHICKIDGQPSRYRGEPQRQHPATTSAA-
MAV_1013|M.avium_104                ADVRMLAHDTGLMENRSARLMWRLCKINGKPSRYRSEPQRQHLAAVPAA-
TH_1805|M.thermoresistible__bu      ADVRALCYDTGLMNP-VARLIWRLCKIDGPPSRYRSEPQRRHVVAAAA--
MSMEG_5682|M.smegmatis_MC2_155      SDVRMLCYDTGLMNP-VAKLVWKICKIDGPPSRYRSEPQREHLVSAA---
MAB_0929|M.abscessus_ATCC_1997      SDVRMLCRGVGMMNP-IAKLVWRVLHIDGRAARYRSEPQRGPLVNYAAPE
                                    .*.* *. .. :*:   *:*:*:: :*:* .:***.** *   .  .   

Mflv_1719|M.gilvum_PYR-GCK          ------------
Mvan_5032|M.vanbaalenii_PYR-1       ------------
Mb0909|M.bovis_AF2122/97            ------------
Rv0885|M.tuberculosis_H37Rv         ------------
MMAR_4647|M.marinum_M               ------------
MUL_0265|M.ulcerans_Agy99           ------------
MLBr_02135|M.leprae_Br4923          ------------
MAV_1013|M.avium_104                ------------
TH_1805|M.thermoresistible__bu      ------------
MSMEG_5682|M.smegmatis_MC2_155      ------------
MAB_0929|M.abscessus_ATCC_1997      AAASDSPSAVPA