For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VRWLDADGGRSFLRALPVLSGNAPPFDIASAPAEPLRLFIEWIEQAAQAGVQEPHAMTISTVDNAGMPRA RVLILKAIDQDGWHFAASSVSQKGRDLSANPAAALTFHWPEVVRQVRVVGAVVDDGDQVSAADFLGRPVG SRAMALTLRQSQPLVDPAEIDAEIEKAHRKLADDPELVPDEWVSYALRPAQIEFWQGSPDRKHQRLSYQW VGDGWERTQLWP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3823 | - | - | 100% (222) | pyridoxamine 5'-phosphate oxidase |
| M. abscessus ATCC 19977 | MAB_0933 | - | 8e-24 | 35.47% (172) | pyridoxamine 5'-phosphate oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2639 | pdxH | 5e-25 | 34.88% (172) | pyridoxamine 5'-phosphate oxidase |
| M. gilvum PYR-GCK | Mflv_1727 | - | 1e-25 | 35.29% (170) | pyridoxamine 5'-phosphate oxidase |
| M. tuberculosis H37Rv | Rv2607 | pdxH | 5e-25 | 34.88% (172) | pyridoxamine 5'-phosphate oxidase |
| M. leprae Br4923 | MLBr_02131 | pdxH | 6e-26 | 37.21% (172) | pyridoxamine 5'-phosphate oxidase |
| M. marinum M | MMAR_4642 | pdxH | 7e-25 | 37.21% (172) | pyridoxamine 5'-phosphate oxidase PdxH |
| M. avium 104 | MAV_1017 | pdxH | 3e-25 | 33.84% (198) | pyridoxamine 5'-phosphate oxidase |
| M. smegmatis MC2 155 | MSMEG_5675 | pdxH | 3e-25 | 36.05% (172) | pyridoxamine 5'-phosphate oxidase |
| M. thermoresistible (build 8) | TH_1808 | pdxH | 1e-25 | 35.50% (169) | PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE PDXH (PNP/PMP |
| M. ulcerans Agy99 | MUL_0257 | pdxH | 3e-19 | 35.76% (151) | pyridoxamine 5'-phosphate oxidase PdxH |
| M. vanbaalenii PYR-1 | Mvan_5024 | - | 2e-27 | 37.65% (170) | pyridoxamine 5'-phosphate oxidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2639|M.bovis_AF2122/97 MDDDAQMVAIDKD--------QLARMRGEYG-PEKDGCGDLDFDWLD---
Rv2607|M.tuberculosis_H37Rv MDDDAQMVAIDKD--------QLARMRGEYG-PEKDGCGDLDFDWLD---
Mflv_1727|M.gilvum_PYR-GCK ------MATSD----------HLARMRVEYGSAEKDGSVDLDADWLD---
Mvan_5024|M.vanbaalenii_PYR-1 ------MGTSD----------YLARMRVEYGSVEKDGSSDLDVDWLGPDP
MSMEG_5675|M.smegmatis_MC2_155 ------MGIPDDPAGSAPENFDLATMRVEY--VEKDGCGDLDVDWLGDDP
TH_1808|M.thermoresistible__bu -VARQEHSEPDNE--------HLAMMRAEYGSVEKDGSADLDVDWLGPDP
MMAR_4642|M.marinum_M ------MTGPNEQ--------RLAAMRVEYGSPEKDASPDLDADWLG---
MUL_0257|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02131|M.leprae_Br4923 ---------------------------MEYGSVEKDGSPDLDTDWLY---
MAV_1017|M.avium_104 ---------------------------MEYGSVEKDGSPDLDVDWLD---
MAB_3823|M.abscessus_ATCC_1997 ------MRWLDAD---------GGRSFLRALPVLSGNAPPFDIASAP---
Mb2639|M.bovis_AF2122/97 -DGWLTLLRRWLNDAQRAGVSEPNAMVLATVAD-GKPVTRSVLCKILDES
Rv2607|M.tuberculosis_H37Rv -DGWLTLLRRWLNDAQRAGVSEPNAMVLATVAD-GKPVTRSVLCKILDES
Mflv_1727|M.gilvum_PYR-GCK -IGWVALLNQWMTEAHDAGVAEPNAMVVATIDGEGRPVTRTVLCKSVDES
Mvan_5024|M.vanbaalenii_PYR-1 ATGWVTLLHQWMAEAEQAGAAEPNAMVVATVDDRGRPVTRTVLCKSVDAS
MSMEG_5675|M.smegmatis_MC2_155 ATGWLTLLQTWINDAWKAGLPDANAMVVGTVDADGRPVTRSVLCKSVDPD
TH_1808|M.thermoresistible__bu ATGWVTLLRRWLADAERAGVAEPNAMVLGTVDARGWPATRSVLCKNIDTD
MMAR_4642|M.marinum_M -HGWLALVRKWIDDAEHAGIAEPNAMVLATVS-QGRPVSRSVLCKAVDEA
MUL_0257|M.ulcerans_Agy99 -------------------------MVLATVS-EGLPVSRSVLCKAVDEA
MLBr_02131|M.leprae_Br4923 -DGWLTLFCKWIDDAERAGVAEPNAMVLATVA-NGRPVSRSVLCKGADEA
MAV_1017|M.avium_104 -DGWVALLRKWIDDAERAGVAEPNAMVLATVTPDGRPASRTVLCKSLDET
MAB_3823|M.abscessus_ATCC_1997 -AEPLRLFIEWIEQAAQAGVQEPHAMTISTVDNAGMPRARVLILKAIDQD
*.:.*: * * :* :: * *
Mb2639|M.bovis_AF2122/97 GVAFFTSYTSAKGEQLAVTPYASATFPWYQLGRQAHVQGPVSKVSTEEIF
Rv2607|M.tuberculosis_H37Rv GVAFFTSYTSAKGEQLAVTPYASATFPWYQLGRQAHVQGPVSKVSTEEIF
Mflv_1727|M.gilvum_PYR-GCK GISFYTNYDSDKGAQLAARPYASATFPWYLLGRQVHVRGRVTKVSAEETA
Mvan_5024|M.vanbaalenii_PYR-1 GVSFYTNYDSEKGRQLAAAPYASATFPWYLVGRQVHVHGAVTKVSAEETA
MSMEG_5675|M.smegmatis_MC2_155 GITFYTNYDSAKGEHLAVNAYASATFPWYQLGRQVHVRGAVTKVSAEETA
TH_1808|M.thermoresistible__bu GLTFFTNYGSAKAADLAATPRASVTFPWYALGRQVHIRGPVTKVSPEVTG
MMAR_4642|M.marinum_M GITFFTSYDSAKGADLAETPYASVTFPWYQLGRQVHVRGPVSRVAAQVTE
MUL_0257|M.ulcerans_Agy99 GITFFTSYDSAKGADLAETPYASVTFPWYQLGRQVHVRGPVSRVAAQVTE
MLBr_02131|M.leprae_Br4923 GIIFFTNYDSDKGDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSE
MAV_1017|M.avium_104 GITFFTNYDSAKADDLAATPYAAVTFPWYQLGRQVHLRGPVSKVTAQVTE
MAB_3823|M.abscessus_ATCC_1997 GWHFAASSVSQKGRDLSANPAAALTFHWPEVVRQVRVVGAVVDDGDQVSA
* * :. * *. .*: . *: ** * : **.:: * * :
Mb2639|M.bovis_AF2122/97 TYWSMRPRGAQLGAWASQQSRPVGSRAQLDNQLAEVTRRFADQDQIPVPP
Rv2607|M.tuberculosis_H37Rv TYWSMRPRGAQLGAWASQQSRPVGSRAQLDNQLAEVTRRFADQDQIPVPP
Mflv_1727|M.gilvum_PYR-GCK DYWSKRPRGSQLGAWASQQSRPIASRAALMQQLADVTARFADVDEVPVPP
Mvan_5024|M.vanbaalenii_PYR-1 DYWSKRPRGSQLGAWASQQSLPIASRAALMQQLTEVTERFADVEEIPVPP
MSMEG_5675|M.smegmatis_MC2_155 EYWSKRPRGSQLGAWASQQSRPIASRAALLEQLAEVTERFADLDEVPVPP
TH_1808|M.thermoresistible__bu DYWVKRPRGSQLGAWASQQSRPIESRAALLARLAEVTERFDGVD-VPVPP
MMAR_4642|M.marinum_M DYWSLRPRGSQLGAWASHQSQPIASRAALLDKLAQVTARFADVERIPVPP
MUL_0257|M.ulcerans_Agy99 DYWSLRPRGSQLGAWASHQSQPIASRAALLYKLAQVTARFADVERIPVPP
MLBr_02131|M.leprae_Br4923 DYWSKRPRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFADSELIPLPP
MAV_1017|M.avium_104 DYWSKRPRGSQLGAWASQQSRPIASRAALLEQLAQVTARFADHERVPVPP
MAB_3823|M.abscessus_ATCC_1997 ADFLGRPVGSRAMALTLRQSQPLVDPAEIDAEIEKAHRKLADDP-ELVPD
: ** *:: * : :** *: . : : .: .. :: . :*
Mb2639|M.bovis_AF2122/97 GWGGYRIAPEIVEFWQGRENRMHNRIRV--ANGRLERLQP--
Rv2607|M.tuberculosis_H37Rv GWGGYRIAPEIVEFWQGRENRMHNRIRV--ANGRLERLQP--
Mflv_1727|M.gilvum_PYR-GCK HWGGYLIAAEVVEFWQGRENRVHNRIRV--RDGAVERLQP--
Mvan_5024|M.vanbaalenii_PYR-1 HWGGYLIAAEVVEFWQGRENRVHNRIRV--CGGQVERLQP--
MSMEG_5675|M.smegmatis_MC2_155 NWGGYRIAPEVVEFWQGRENRVHNRIRV--TGGRVERLQP--
TH_1808|M.thermoresistible__bu DWGGYRITAETVEFWQGRENRLHNRIVVG-ADGTVRRLQP--
MMAR_4642|M.marinum_M NWGGYLIAAEVVEFWQGRENRVHNRIRV--SGAQIERLQP--
MUL_0257|M.ulcerans_Agy99 NWGGYLIAAEVVEFWQGRENRVHNRIRV--SGTQIERLQP--
MLBr_02131|M.leprae_Br4923 NWGGYLIVPEVVEFWQGRENRVHNRIRV--TGGCIERLQP--
MAV_1017|M.avium_104 GWGGYLIAADVVEFWQGRENRLHNRIRV--TGNRVERLQP--
MAB_3823|M.abscessus_ATCC_1997 EWVSYALRPAQIEFWQGSPDRKHQRLSYQWVGDGWERTQLWP
* .* : . :***** :* *:*: . .* *