For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
EYGSVEKDGSPDLDTDWLYDGWLTLFCKWIDDAERAGVAEPNAMVLATVANGRPVSRSVLCKGADEAGII FFTNYDSDKGDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDYWSKRPRGSQLGAWASHQSRPI ASRTALLDQLLEVTVRFADSELIPLPPNWGGYLIVPEVVEFWQGRENRVHNRIRVTGGCIERLQP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02131 | pdxH | - | 100% (206) | pyridoxamine 5'-phosphate oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2639 | pdxH | 2e-83 | 69.27% (205) | pyridoxamine 5'-phosphate oxidase |
| M. gilvum PYR-GCK | Mflv_1727 | - | 2e-85 | 70.53% (207) | pyridoxamine 5'-phosphate oxidase |
| M. tuberculosis H37Rv | Rv2607 | pdxH | 2e-83 | 69.27% (205) | pyridoxamine 5'-phosphate oxidase |
| M. abscessus ATCC 19977 | MAB_0933 | - | 9e-83 | 70.24% (205) | pyridoxamine 5'-phosphate oxidase |
| M. marinum M | MMAR_4642 | pdxH | 5e-97 | 81.07% (206) | pyridoxamine 5'-phosphate oxidase PdxH |
| M. avium 104 | MAV_1017 | pdxH | 2e-97 | 80.19% (207) | pyridoxamine 5'-phosphate oxidase |
| M. smegmatis MC2 155 | MSMEG_5675 | pdxH | 3e-82 | 70.14% (211) | pyridoxamine 5'-phosphate oxidase |
| M. thermoresistible (build 8) | TH_1808 | pdxH | 3e-78 | 69.19% (211) | PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE PDXH (PNP/PMP |
| M. ulcerans Agy99 | MUL_0257 | pdxH | 1e-73 | 80.86% (162) | pyridoxamine 5'-phosphate oxidase PdxH |
| M. vanbaalenii PYR-1 | Mvan_5024 | - | 1e-83 | 69.67% (211) | pyridoxamine 5'-phosphate oxidase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4642|M.marinum_M --------MTGPNEQRLAAMRVEYGSPEKDASPDLDADWLG----HGWLA
MUL_0257|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02131|M.leprae_Br4923 ---------------------MEYGSVEKDGSPDLDTDWLY----DGWLT
MAV_1017|M.avium_104 ---------------------MEYGSVEKDGSPDLDVDWLD----DGWVA
MAB_0933|M.abscessus_ATCC_1997 ---------------MTEWLRSDYRPGEKDGSGDLDVDWL----ADGWLP
TH_1808|M.thermoresistible__bu ---VARQEHSEPDNEHLAMMRAEYGSVEKDGSADLDVDWLGPDPATGWVT
Mflv_1727|M.gilvum_PYR-GCK ----------MATSDHLARMRVEYGSAEKDGSVDLDADWLD----IGWVA
Mvan_5024|M.vanbaalenii_PYR-1 ----------MGTSDYLARMRVEYGSVEKDGSSDLDVDWLGPDPATGWVT
MSMEG_5675|M.smegmatis_MC2_155 MGIPDDPAGSAPENFDLATMRVEY--VEKDGCGDLDVDWLGDDPATGWLT
Mb2639|M.bovis_AF2122/97 --MDDDAQMVAIDKDQLARMRGEYG-PEKDGCGDLDFDWLD----DGWLT
Rv2607|M.tuberculosis_H37Rv --MDDDAQMVAIDKDQLARMRGEYG-PEKDGCGDLDFDWLD----DGWLT
MMAR_4642|M.marinum_M LVRKWIDDAEHAGIAEPNAMVLATVS-QGRPVSRSVLCKAVDEAGITFFT
MUL_0257|M.ulcerans_Agy99 -------------------MVLATVS-EGLPVSRSVLCKAVDEAGITFFT
MLBr_02131|M.leprae_Br4923 LFCKWIDDAERAGVAEPNAMVLATVA-NGRPVSRSVLCKGADEAGIIFFT
MAV_1017|M.avium_104 LLRKWIDDAERAGVAEPNAMVLATVTPDGRPASRTVLCKSLDETGITFFT
MAB_0933|M.abscessus_ATCC_1997 LLHKWFDLAVASGIPEPNAMVLATVDD-GRPVTRTVLCKGFDAAGVTFFS
TH_1808|M.thermoresistible__bu LLRRWLADAERAGVAEPNAMVLGTVDARGWPATRSVLCKNIDTDGLTFFT
Mflv_1727|M.gilvum_PYR-GCK LLNQWMTEAHDAGVAEPNAMVVATIDGEGRPVTRTVLCKSVDESGISFYT
Mvan_5024|M.vanbaalenii_PYR-1 LLHQWMAEAEQAGAAEPNAMVVATVDDRGRPVTRTVLCKSVDASGVSFYT
MSMEG_5675|M.smegmatis_MC2_155 LLQTWINDAWKAGLPDANAMVVGTVDADGRPVTRSVLCKSVDPDGITFYT
Mb2639|M.bovis_AF2122/97 LLRRWLNDAQRAGVSEPNAMVLATVA-DGKPVTRSVLCKILDESGVAFFT
Rv2607|M.tuberculosis_H37Rv LLRRWLNDAQRAGVSEPNAMVLATVA-DGKPVTRSVLCKILDESGVAFFT
**:.*: * *.:*:**** * *: *::
MMAR_4642|M.marinum_M SYDSAKGADLAETPYASVTFPWYQLGRQVHVRGPVSRVAAQVTEDYWSLR
MUL_0257|M.ulcerans_Agy99 SYDSAKGADLAETPYASVTFPWYQLGRQVHVRGPVSRVAAQVTEDYWSLR
MLBr_02131|M.leprae_Br4923 NYDSDKGDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDYWSKR
MAV_1017|M.avium_104 NYDSAKADDLAATPYAAVTFPWYQLGRQVHLRGPVSKVTAQVTEDYWSKR
MAB_0933|M.abscessus_ATCC_1997 NYDSAKGRQLAATPYASVTFPWYALGRQVHVRGRVTKVDPAQTADYWTNR
TH_1808|M.thermoresistible__bu NYGSAKAADLAATPRASVTFPWYALGRQVHIRGPVTKVSPEVTGDYWVKR
Mflv_1727|M.gilvum_PYR-GCK NYDSDKGAQLAARPYASATFPWYLLGRQVHVRGRVTKVSAEETADYWSKR
Mvan_5024|M.vanbaalenii_PYR-1 NYDSEKGRQLAAAPYASATFPWYLVGRQVHVHGAVTKVSAEETADYWSKR
MSMEG_5675|M.smegmatis_MC2_155 NYDSAKGEHLAVNAYASATFPWYQLGRQVHVRGAVTKVSAEETAEYWSKR
Mb2639|M.bovis_AF2122/97 SYTSAKGEQLAVTPYASATFPWYQLGRQAHVQGPVSKVSTEEIFTYWSMR
Rv2607|M.tuberculosis_H37Rv SYTSAKGEQLAVTPYASATFPWYQLGRQAHVQGPVSKVSTEEIFTYWSMR
.* * *. .** . *:.***** :***.*::* *: * . ** *
MMAR_4642|M.marinum_M PRGSQLGAWASHQSQPIASRAALLDKLAQVTARFADVERIPVPPNWGGYL
MUL_0257|M.ulcerans_Agy99 PRGSQLGAWASHQSQPIASRAALLYKLAQVTARFADVERIPVPPNWGGYL
MLBr_02131|M.leprae_Br4923 PRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFADSELIPLPPNWGGYL
MAV_1017|M.avium_104 PRGSQLGAWASQQSRPIASRAALLEQLAQVTARFADHERVPVPPGWGGYL
MAB_0933|M.abscessus_ATCC_1997 PRGSQLGAWASQQSAPIESREALLAQLGDVTQRFAGLDQIPVPPQWGGYV
TH_1808|M.thermoresistible__bu PRGSQLGAWASQQSRPIESRAALLARLAEVTERFDGVD-VPVPPDWGGYR
Mflv_1727|M.gilvum_PYR-GCK PRGSQLGAWASQQSRPIASRAALMQQLADVTARFADVDEVPVPPHWGGYL
Mvan_5024|M.vanbaalenii_PYR-1 PRGSQLGAWASQQSLPIASRAALMQQLTEVTERFADVEEIPVPPHWGGYL
MSMEG_5675|M.smegmatis_MC2_155 PRGSQLGAWASQQSRPIASRAALLEQLAEVTERFADLDEVPVPPNWGGYR
Mb2639|M.bovis_AF2122/97 PRGAQLGAWASQQSRPVGSRAQLDNQLAEVTRRFADQDQIPVPPGWGGYR
Rv2607|M.tuberculosis_H37Rv PRGAQLGAWASQQSRPVGSRAQLDNQLAEVTRRFADQDQIPVPPGWGGYR
***:*******:** *: ** * :* :** ** . : :*:** ****
MMAR_4642|M.marinum_M IAAEVVEFWQGRENRVHNRIRV-SGAQIERLQP
MUL_0257|M.ulcerans_Agy99 IAAEVVEFWQGRENRVHNRIRV-SGTQIERLQP
MLBr_02131|M.leprae_Br4923 IVPEVVEFWQGRENRVHNRIRV-TGGCIERLQP
MAV_1017|M.avium_104 IAADVVEFWQGRENRLHNRIRV-TGNRVERLQP
MAB_0933|M.abscessus_ATCC_1997 IAPETVEFWQGRENRVHNRIVV-TDGRVERLQP
TH_1808|M.thermoresistible__bu ITAETVEFWQGRENRLHNRIVVGADGTVRRLQP
Mflv_1727|M.gilvum_PYR-GCK IAAEVVEFWQGRENRVHNRIRV-RDGAVERLQP
Mvan_5024|M.vanbaalenii_PYR-1 IAAEVVEFWQGRENRVHNRIRV-CGGQVERLQP
MSMEG_5675|M.smegmatis_MC2_155 IAPEVVEFWQGRENRVHNRIRV-TGGRVERLQP
Mb2639|M.bovis_AF2122/97 IAPEIVEFWQGRENRMHNRIRV-ANGRLERLQP
Rv2607|M.tuberculosis_H37Rv IAPEIVEFWQGRENRMHNRIRV-ANGRLERLQP
*..: **********:**** * . :.****