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GTSDYLARMRVEYGSVEKDGSSDLDVDWLGPDPATGWVTLLHQWMAEAEQAGAAEPNAMVVATVDDRGRP VTRTVLCKSVDASGVSFYTNYDSEKGRQLAAAPYASATFPWYLVGRQVHVHGAVTKVSAEETADYWSKRP RGSQLGAWASQQSLPIASRAALMQQLTEVTERFADVEEIPVPPHWGGYLIAAEVVEFWQGRENRVHNRIR VCGGQVERLQP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5024 | - | - | 100% (222) | pyridoxamine 5'-phosphate oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2639 | pdxH | 9e-83 | 67.43% (218) | pyridoxamine 5'-phosphate oxidase |
| M. gilvum PYR-GCK | Mflv_1727 | - | 1e-106 | 83.33% (222) | pyridoxamine 5'-phosphate oxidase |
| M. tuberculosis H37Rv | Rv2607 | pdxH | 9e-83 | 67.43% (218) | pyridoxamine 5'-phosphate oxidase |
| M. leprae Br4923 | MLBr_02131 | pdxH | 3e-84 | 69.67% (211) | pyridoxamine 5'-phosphate oxidase |
| M. abscessus ATCC 19977 | MAB_0933 | - | 1e-84 | 69.95% (213) | pyridoxamine 5'-phosphate oxidase |
| M. marinum M | MMAR_4642 | pdxH | 8e-88 | 70.83% (216) | pyridoxamine 5'-phosphate oxidase PdxH |
| M. avium 104 | MAV_1017 | pdxH | 1e-88 | 72.04% (211) | pyridoxamine 5'-phosphate oxidase |
| M. smegmatis MC2 155 | MSMEG_5675 | pdxH | 1e-96 | 77.78% (216) | pyridoxamine 5'-phosphate oxidase |
| M. thermoresistible (build 8) | TH_1808 | pdxH | 4e-90 | 70.91% (220) | PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE PDXH (PNP/PMP |
| M. ulcerans Agy99 | MUL_0257 | pdxH | 1e-67 | 73.01% (163) | pyridoxamine 5'-phosphate oxidase PdxH |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5024|M.vanbaalenii_PYR-1 ----------MGTSDYLARMRVEYGSVEKDGSSDLDVDWLGPDPATGWVT
Mflv_1727|M.gilvum_PYR-GCK ----------MATSDHLARMRVEYGSAEKDGSVDLDADWLD----IGWVA
MAB_0933|M.abscessus_ATCC_1997 ---------------MTEWLRSDYRPGEKDGSGDLDVDWL----ADGWLP
TH_1808|M.thermoresistible__bu ---VARQEHSEPDNEHLAMMRAEYGSVEKDGSADLDVDWLGPDPATGWVT
MMAR_4642|M.marinum_M --------MTGPNEQRLAAMRVEYGSPEKDASPDLDADWLG----HGWLA
MUL_0257|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02131|M.leprae_Br4923 ---------------------MEYGSVEKDGSPDLDTDWLY----DGWLT
MAV_1017|M.avium_104 ---------------------MEYGSVEKDGSPDLDVDWLD----DGWVA
MSMEG_5675|M.smegmatis_MC2_155 MGIPDDPAGSAPENFDLATMRVEY--VEKDGCGDLDVDWLGDDPATGWLT
Mb2639|M.bovis_AF2122/97 --MDDDAQMVAIDKDQLARMRGEYG-PEKDGCGDLDFDWLD----DGWLT
Rv2607|M.tuberculosis_H37Rv --MDDDAQMVAIDKDQLARMRGEYG-PEKDGCGDLDFDWLD----DGWLT
Mvan_5024|M.vanbaalenii_PYR-1 LLHQWMAEAEQAGAAEPNAMVVATVDDRGRPVTRTVLCKSVDASGVSFYT
Mflv_1727|M.gilvum_PYR-GCK LLNQWMTEAHDAGVAEPNAMVVATIDGEGRPVTRTVLCKSVDESGISFYT
MAB_0933|M.abscessus_ATCC_1997 LLHKWFDLAVASGIPEPNAMVLATVDD-GRPVTRTVLCKGFDAAGVTFFS
TH_1808|M.thermoresistible__bu LLRRWLADAERAGVAEPNAMVLGTVDARGWPATRSVLCKNIDTDGLTFFT
MMAR_4642|M.marinum_M LVRKWIDDAEHAGIAEPNAMVLATVS-QGRPVSRSVLCKAVDEAGITFFT
MUL_0257|M.ulcerans_Agy99 -------------------MVLATVS-EGLPVSRSVLCKAVDEAGITFFT
MLBr_02131|M.leprae_Br4923 LFCKWIDDAERAGVAEPNAMVLATVA-NGRPVSRSVLCKGADEAGIIFFT
MAV_1017|M.avium_104 LLRKWIDDAERAGVAEPNAMVLATVTPDGRPASRTVLCKSLDETGITFFT
MSMEG_5675|M.smegmatis_MC2_155 LLQTWINDAWKAGLPDANAMVVGTVDADGRPVTRSVLCKSVDPDGITFYT
Mb2639|M.bovis_AF2122/97 LLRRWLNDAQRAGVSEPNAMVLATVA-DGKPVTRSVLCKILDESGVAFFT
Rv2607|M.tuberculosis_H37Rv LLRRWLNDAQRAGVSEPNAMVLATVA-DGKPVTRSVLCKILDESGVAFFT
**:.*: * *.:*:**** * *: *::
Mvan_5024|M.vanbaalenii_PYR-1 NYDSEKGRQLAAAPYASATFPWYLVGRQVHVHGAVTKVSAEETADYWSKR
Mflv_1727|M.gilvum_PYR-GCK NYDSDKGAQLAARPYASATFPWYLLGRQVHVRGRVTKVSAEETADYWSKR
MAB_0933|M.abscessus_ATCC_1997 NYDSAKGRQLAATPYASVTFPWYALGRQVHVRGRVTKVDPAQTADYWTNR
TH_1808|M.thermoresistible__bu NYGSAKAADLAATPRASVTFPWYALGRQVHIRGPVTKVSPEVTGDYWVKR
MMAR_4642|M.marinum_M SYDSAKGADLAETPYASVTFPWYQLGRQVHVRGPVSRVAAQVTEDYWSLR
MUL_0257|M.ulcerans_Agy99 SYDSAKGADLAETPYASVTFPWYQLGRQVHVRGPVSRVAAQVTEDYWSLR
MLBr_02131|M.leprae_Br4923 NYDSDKGDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDYWSKR
MAV_1017|M.avium_104 NYDSAKADDLAATPYAAVTFPWYQLGRQVHLRGPVSKVTAQVTEDYWSKR
MSMEG_5675|M.smegmatis_MC2_155 NYDSAKGEHLAVNAYASATFPWYQLGRQVHVRGAVTKVSAEETAEYWSKR
Mb2639|M.bovis_AF2122/97 SYTSAKGEQLAVTPYASATFPWYQLGRQAHVQGPVSKVSTEEIFTYWSMR
Rv2607|M.tuberculosis_H37Rv SYTSAKGEQLAVTPYASATFPWYQLGRQAHVQGPVSKVSTEEIFTYWSMR
.* * *. .** . *:.***** :***.*::* *: * . ** *
Mvan_5024|M.vanbaalenii_PYR-1 PRGSQLGAWASQQSLPIASRAALMQQLTEVTERFADVEEIPVPPHWGGYL
Mflv_1727|M.gilvum_PYR-GCK PRGSQLGAWASQQSRPIASRAALMQQLADVTARFADVDEVPVPPHWGGYL
MAB_0933|M.abscessus_ATCC_1997 PRGSQLGAWASQQSAPIESREALLAQLGDVTQRFAGLDQIPVPPQWGGYV
TH_1808|M.thermoresistible__bu PRGSQLGAWASQQSRPIESRAALLARLAEVTERFDGVD-VPVPPDWGGYR
MMAR_4642|M.marinum_M PRGSQLGAWASHQSQPIASRAALLDKLAQVTARFADVERIPVPPNWGGYL
MUL_0257|M.ulcerans_Agy99 PRGSQLGAWASHQSQPIASRAALLYKLAQVTARFADVERIPVPPNWGGYL
MLBr_02131|M.leprae_Br4923 PRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFADSELIPLPPNWGGYL
MAV_1017|M.avium_104 PRGSQLGAWASQQSRPIASRAALLEQLAQVTARFADHERVPVPPGWGGYL
MSMEG_5675|M.smegmatis_MC2_155 PRGSQLGAWASQQSRPIASRAALLEQLAEVTERFADLDEVPVPPNWGGYR
Mb2639|M.bovis_AF2122/97 PRGAQLGAWASQQSRPVGSRAQLDNQLAEVTRRFADQDQIPVPPGWGGYR
Rv2607|M.tuberculosis_H37Rv PRGAQLGAWASQQSRPVGSRAQLDNQLAEVTRRFADQDQIPVPPGWGGYR
***:*******:** *: ** * :* :** ** . : :*:** ****
Mvan_5024|M.vanbaalenii_PYR-1 IAAEVVEFWQGRENRVHNRIRV-CGGQVERLQP
Mflv_1727|M.gilvum_PYR-GCK IAAEVVEFWQGRENRVHNRIRV-RDGAVERLQP
MAB_0933|M.abscessus_ATCC_1997 IAPETVEFWQGRENRVHNRIVV-TDGRVERLQP
TH_1808|M.thermoresistible__bu ITAETVEFWQGRENRLHNRIVVGADGTVRRLQP
MMAR_4642|M.marinum_M IAAEVVEFWQGRENRVHNRIRV-SGAQIERLQP
MUL_0257|M.ulcerans_Agy99 IAAEVVEFWQGRENRVHNRIRV-SGTQIERLQP
MLBr_02131|M.leprae_Br4923 IVPEVVEFWQGRENRVHNRIRV-TGGCIERLQP
MAV_1017|M.avium_104 IAADVVEFWQGRENRLHNRIRV-TGNRVERLQP
MSMEG_5675|M.smegmatis_MC2_155 IAPEVVEFWQGRENRVHNRIRV-TGGRVERLQP
Mb2639|M.bovis_AF2122/97 IAPEIVEFWQGRENRMHNRIRV-ANGRLERLQP
Rv2607|M.tuberculosis_H37Rv IAPEIVEFWQGRENRMHNRIRV-ANGRLERLQP
*..: **********:**** * . :.****