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M. thermoresistible (build 8) TH_1808 (pdxH)

annotation: PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE PDXH (PNP/PMP OXIDASE) (PYRIDOXINEPHOSPHATE OXIDASE) (PNPOX) (PYRIDOXINE 5'-PHOSPHATE OXIDASE)
coordinates: 3538208 - 3538897
length: 230

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_1808 pdxH - 100% (230) PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE PDXH (PNP/PMP OXIDASE) (PYRIDOXINEPHOSPHATE OXIDASE) (PNPOX) (PYRIDOXINE 5'-PHOSPHATE OXIDASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2639 pdxH 1e-76 66.06% (221) pyridoxamine 5'-phosphate oxidase
M. gilvum PYR-GCK Mflv_1727 - 2e-84 68.64% (220) pyridoxamine 5'-phosphate oxidase
M. tuberculosis H37Rv Rv2607 pdxH 1e-76 66.06% (221) pyridoxamine 5'-phosphate oxidase
M. leprae Br4923 MLBr_02131 pdxH 2e-78 69.19% (211) pyridoxamine 5'-phosphate oxidase
M. abscessus ATCC 19977 MAB_0933 - 2e-79 68.22% (214) pyridoxamine 5'-phosphate oxidase
M. marinum M MMAR_4642 pdxH 2e-81 66.22% (222) pyridoxamine 5'-phosphate oxidase PdxH
M. avium 104 MAV_1017 pdxH 3e-84 73.46% (211) pyridoxamine 5'-phosphate oxidase
M. smegmatis MC2 155 MSMEG_5675 pdxH 3e-87 70.54% (224) pyridoxamine 5'-phosphate oxidase
M. ulcerans Agy99 MUL_0257 pdxH 8e-60 68.29% (164) pyridoxamine 5'-phosphate oxidase PdxH
M. vanbaalenii PYR-1 Mvan_5024 - 7e-90 70.91% (220) pyridoxamine 5'-phosphate oxidase

CLUSTAL 2.0.9 multiple sequence alignment


TH_1808|M.thermoresistible__bu      ---VARQEHSEPDNEHLAMMRAEYGSVEKDGSADLDVDWLGPDPATGWVT
MAB_0933|M.abscessus_ATCC_1997      ---------------MTEWLRSDYRPGEKDGSGDLDVDWL----ADGWLP
MMAR_4642|M.marinum_M               --------MTGPNEQRLAAMRVEYGSPEKDASPDLDADWLG----HGWLA
MUL_0257|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02131|M.leprae_Br4923          ---------------------MEYGSVEKDGSPDLDTDWLY----DGWLT
MAV_1017|M.avium_104                ---------------------MEYGSVEKDGSPDLDVDWLD----DGWVA
Mflv_1727|M.gilvum_PYR-GCK          ----------MATSDHLARMRVEYGSAEKDGSVDLDADWLD----IGWVA
Mvan_5024|M.vanbaalenii_PYR-1       ----------MGTSDYLARMRVEYGSVEKDGSSDLDVDWLGPDPATGWVT
MSMEG_5675|M.smegmatis_MC2_155      MGIPDDPAGSAPENFDLATMRVEY--VEKDGCGDLDVDWLGDDPATGWLT
Mb2639|M.bovis_AF2122/97            --MDDDAQMVAIDKDQLARMRGEYG-PEKDGCGDLDFDWLD----DGWLT
Rv2607|M.tuberculosis_H37Rv         --MDDDAQMVAIDKDQLARMRGEYG-PEKDGCGDLDFDWLD----DGWLT
                                                                                      

TH_1808|M.thermoresistible__bu      LLRRWLADAERAGVAEPNAMVLGTVDARGWPATRSVLCKNIDTDGLTFFT
MAB_0933|M.abscessus_ATCC_1997      LLHKWFDLAVASGIPEPNAMVLATVDD-GRPVTRTVLCKGFDAAGVTFFS
MMAR_4642|M.marinum_M               LVRKWIDDAEHAGIAEPNAMVLATVS-QGRPVSRSVLCKAVDEAGITFFT
MUL_0257|M.ulcerans_Agy99           -------------------MVLATVS-EGLPVSRSVLCKAVDEAGITFFT
MLBr_02131|M.leprae_Br4923          LFCKWIDDAERAGVAEPNAMVLATVA-NGRPVSRSVLCKGADEAGIIFFT
MAV_1017|M.avium_104                LLRKWIDDAERAGVAEPNAMVLATVTPDGRPASRTVLCKSLDETGITFFT
Mflv_1727|M.gilvum_PYR-GCK          LLNQWMTEAHDAGVAEPNAMVVATIDGEGRPVTRTVLCKSVDESGISFYT
Mvan_5024|M.vanbaalenii_PYR-1       LLHQWMAEAEQAGAAEPNAMVVATVDDRGRPVTRTVLCKSVDASGVSFYT
MSMEG_5675|M.smegmatis_MC2_155      LLQTWINDAWKAGLPDANAMVVGTVDADGRPVTRSVLCKSVDPDGITFYT
Mb2639|M.bovis_AF2122/97            LLRRWLNDAQRAGVSEPNAMVLATVA-DGKPVTRSVLCKILDESGVAFFT
Rv2607|M.tuberculosis_H37Rv         LLRRWLNDAQRAGVSEPNAMVLATVA-DGKPVTRSVLCKILDESGVAFFT
                                                       **:.*:   * *.:*:****  *  *: *::

TH_1808|M.thermoresistible__bu      NYGSAKAADLAATPRASVTFPWYALGRQVHIRGPVTKVSPEVTGDYWVKR
MAB_0933|M.abscessus_ATCC_1997      NYDSAKGRQLAATPYASVTFPWYALGRQVHVRGRVTKVDPAQTADYWTNR
MMAR_4642|M.marinum_M               SYDSAKGADLAETPYASVTFPWYQLGRQVHVRGPVSRVAAQVTEDYWSLR
MUL_0257|M.ulcerans_Agy99           SYDSAKGADLAETPYASVTFPWYQLGRQVHVRGPVSRVAAQVTEDYWSLR
MLBr_02131|M.leprae_Br4923          NYDSDKGDDLAATPYASVTFPWYQLGRQVHIRGPVSTVDPQVSEDYWSKR
MAV_1017|M.avium_104                NYDSAKADDLAATPYAAVTFPWYQLGRQVHLRGPVSKVTAQVTEDYWSKR
Mflv_1727|M.gilvum_PYR-GCK          NYDSDKGAQLAARPYASATFPWYLLGRQVHVRGRVTKVSAEETADYWSKR
Mvan_5024|M.vanbaalenii_PYR-1       NYDSEKGRQLAAAPYASATFPWYLVGRQVHVHGAVTKVSAEETADYWSKR
MSMEG_5675|M.smegmatis_MC2_155      NYDSAKGEHLAVNAYASATFPWYQLGRQVHVRGAVTKVSAEETAEYWSKR
Mb2639|M.bovis_AF2122/97            SYTSAKGEQLAVTPYASATFPWYQLGRQAHVQGPVSKVSTEEIFTYWSMR
Rv2607|M.tuberculosis_H37Rv         SYTSAKGEQLAVTPYASATFPWYQLGRQAHVQGPVSKVSTEEIFTYWSMR
                                    .* * *. .**  . *:.***** :***.*::* *: * .     **  *

TH_1808|M.thermoresistible__bu      PRGSQLGAWASQQSRPIESRAALLARLAEVTERFDGVD-VPVPPDWGGYR
MAB_0933|M.abscessus_ATCC_1997      PRGSQLGAWASQQSAPIESREALLAQLGDVTQRFAGLDQIPVPPQWGGYV
MMAR_4642|M.marinum_M               PRGSQLGAWASHQSQPIASRAALLDKLAQVTARFADVERIPVPPNWGGYL
MUL_0257|M.ulcerans_Agy99           PRGSQLGAWASHQSQPIASRAALLYKLAQVTARFADVERIPVPPNWGGYL
MLBr_02131|M.leprae_Br4923          PRGSQLGAWASHQSRPIASRTALLDQLLEVTVRFADSELIPLPPNWGGYL
MAV_1017|M.avium_104                PRGSQLGAWASQQSRPIASRAALLEQLAQVTARFADHERVPVPPGWGGYL
Mflv_1727|M.gilvum_PYR-GCK          PRGSQLGAWASQQSRPIASRAALMQQLADVTARFADVDEVPVPPHWGGYL
Mvan_5024|M.vanbaalenii_PYR-1       PRGSQLGAWASQQSLPIASRAALMQQLTEVTERFADVEEIPVPPHWGGYL
MSMEG_5675|M.smegmatis_MC2_155      PRGSQLGAWASQQSRPIASRAALLEQLAEVTERFADLDEVPVPPNWGGYR
Mb2639|M.bovis_AF2122/97            PRGAQLGAWASQQSRPVGSRAQLDNQLAEVTRRFADQDQIPVPPGWGGYR
Rv2607|M.tuberculosis_H37Rv         PRGAQLGAWASQQSRPVGSRAQLDNQLAEVTRRFADQDQIPVPPGWGGYR
                                    ***:*******:** *: **  *  :* :** ** . : :*:** **** 

TH_1808|M.thermoresistible__bu      ITAETVEFWQGRENRLHNRIVVGADGTVRRLQP
MAB_0933|M.abscessus_ATCC_1997      IAPETVEFWQGRENRVHNRIVV-TDGRVERLQP
MMAR_4642|M.marinum_M               IAAEVVEFWQGRENRVHNRIRV-SGAQIERLQP
MUL_0257|M.ulcerans_Agy99           IAAEVVEFWQGRENRVHNRIRV-SGTQIERLQP
MLBr_02131|M.leprae_Br4923          IVPEVVEFWQGRENRVHNRIRV-TGGCIERLQP
MAV_1017|M.avium_104                IAADVVEFWQGRENRLHNRIRV-TGNRVERLQP
Mflv_1727|M.gilvum_PYR-GCK          IAAEVVEFWQGRENRVHNRIRV-RDGAVERLQP
Mvan_5024|M.vanbaalenii_PYR-1       IAAEVVEFWQGRENRVHNRIRV-CGGQVERLQP
MSMEG_5675|M.smegmatis_MC2_155      IAPEVVEFWQGRENRVHNRIRV-TGGRVERLQP
Mb2639|M.bovis_AF2122/97            IAPEIVEFWQGRENRMHNRIRV-ANGRLERLQP
Rv2607|M.tuberculosis_H37Rv         IAPEIVEFWQGRENRMHNRIRV-ANGRLERLQP
                                    *..: **********:**** *  .  :.****

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_1808	pdxH	-	100% (230)	PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE PDXH (PNP/PMP OXIDASE) (PYRIDOXINEPHOSPHATE OXIDASE) (PNPOX) (PYRIDOXINE 5'-PHOSPHATE OXIDASE)