For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MARPVSILDLARVAPHETVAESFAASVEIARHAETLGFHRVWYAEHHNMRSIASSATSVLIAHVATQTST IRLGAGGIMLPNHSPLQIAEQFGTLETLHPGRIDLGLGRAPGTDQVTLRALRHGPGDAEHFPQDVLELQA FLGDQSRVPGVTATPGHGTQVPLYILGSSLFGAKLAAVLGLPYGFASHFAPPALQDAVALYRREFQPSQQ LDAPYVLAGVNVIAADDEATARDQHQAALIERAKLFLHRSGGPRLTDEEALAALESPAGRQIQSMTKYFA VGTADQVGAYLEDFAQLADADELIVVPNAPDRKLQLRSLEIVAEVSGLTLRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3639 | - | - | 100% (332) | putative luciferase-like protein |
| M. abscessus ATCC 19977 | MAB_4233c | - | 5e-43 | 32.80% (372) | putative monooxygenase (luciferase-like) |
| M. abscessus ATCC 19977 | MAB_0527c | - | 2e-10 | 31.73% (104) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1971 | - | 4e-08 | 24.19% (124) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_2237 | - | 3e-55 | 40.31% (325) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3618 | - | 8e-10 | 32.69% (104) | monooxygenase |
| M. leprae Br4923 | MLBr_01106 | - | 1e-05 | 27.45% (102) | hypothetical protein MLBr_01106 |
| M. marinum M | MMAR_4179 | - | 1e-54 | 40.99% (322) | monooxygenase |
| M. avium 104 | MAV_1409 | - | 6e-54 | 38.94% (321) | alkanal monooxygenase alpha chain |
| M. smegmatis MC2 155 | MSMEG_5029 | - | 2e-58 | 41.21% (330) | alkanal monooxygenase alpha chain |
| M. thermoresistible (build 8) | TH_4411 | - | 1e-68 | 43.94% (330) | PUTATIVE putative alkanal monooxygenase alpha chain |
| M. ulcerans Agy99 | MUL_4481 | - | 2e-54 | 40.81% (321) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_4458 | - | 5e-55 | 40.43% (324) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3639|M.abscessus_ATCC_1997 -------------MARPVSILDLARVAPHETVAESFAASVEIARHAETLG
TH_4411|M.thermoresistible__bu ---------------VPLSILDLVPISEGSTARDAIAASMNSARLADQLG
MMAR_4179|M.marinum_M ---------------MRLSVLDLVPVRTDQSTRDALAATVSLAQTAERLG
MUL_4481|M.ulcerans_Agy99 ------------MGSVRLSVLDLVPVRTDQSTRDALAATVSLAQTAERLG
MAV_1409|M.avium_104 ---------------MRLSVLDLVPVRTDQTTGDALAATVALAQAADRLG
Mflv_2237|M.gilvum_PYR-GCK ---------------MRLSVLDLVPVRSDQSTGDALAATTLLAQAADRLG
Mvan_4458|M.vanbaalenii_PYR-1 --------------MMRLSVLDLVPVRSDQSTSDAIAASTLLAQTADRLG
MSMEG_5029|M.smegmatis_MC2_155 ---------------MRLSVLDLVPVRTDQTTADALAATTHLAQTADRLG
MLBr_01106|M.leprae_Br4923 MLAENILMAGGVDSIGRISVLDLVPVRTDQSSRHALVATVQLTQTANQRN
Rv3618|M.tuberculosis_H37Rv -----------MKAPLRFGVFITPFHPTGQSPTVALQYDMERVVALDRLG
Mb1971|M.bovis_AF2122/97 ---------------MEIGIFLMPAHPPERTLYDATRWDLDVIELADQLG
..:: : : : .
MAB_3639|M.abscessus_ATCC_1997 FHRVWYAEHHNMRSIASSATSVLIAHVATQTSTIRLGAGGIMLPNHSPLQ
TH_4411|M.thermoresistible__bu YHRLWFAEHHNTPNLAASATALLISQAATVTERIRVGAGGVMLPNHAPLM
MMAR_4179|M.marinum_M FTRYWVAEHHNMASVGATSPPVLIAYLAAQTTHLRLGSGGVMLPNHAPLA
MUL_4481|M.ulcerans_Agy99 FTRYWVAEHHNMASVGATSPPVLIAYLAAQTTHLRLGSGGVMLPNHAPLA
MAV_1409|M.avium_104 FTRYWVAEHHNMPSVGATSPPVLLAYLAPQTTRLRLGSGGVMLPNHAPLA
Mflv_2237|M.gilvum_PYR-GCK YTRYWVAEHHNMPAVAATSPPVLIAHLAAHTAAIRLGSGGVMLPNHAPLA
Mvan_4458|M.vanbaalenii_PYR-1 YTRYWVAEHHNMPSVAATSPPVLIAHLAAHTASMRVGSGGVMLPNHAPLA
MSMEG_5029|M.smegmatis_MC2_155 YHRFWVAEHHNMPAVAATSPPVLIAHLAAHTSQLRLGSGGVMLPNHAPLA
MLBr_01106|M.leprae_Br4923 FSSRLVVEDYSMLSVGATSPPVLITYLAVQTTRIEL------LGNLGAVS
Rv3618|M.tuberculosis_H37Rv YDEAWFGEHHSGGYELIACPEVFIAAAAERTTHIRLGTGVVSLPYHHPLM
Mb1971|M.bovis_AF2122/97 YVEAWVGEHFTVPWEPICAPDLLLAQALLRTQQIKLAPGAHLLPYHHPVE
: *... .. :::: * :.: * .:
MAB_3639|M.abscessus_ATCC_1997 IAEQFGTLETLHPGRIDLGLGR--------APGTDQVTLRALRHGPG---
TH_4411|M.thermoresistible__bu VAEQYGTLANIHGDRIDLGLGR--------APGTDMMTARALSRSSA---
MMAR_4179|M.marinum_M VAEQFALLEAAAPGRIDLGIGR--------APGSDPVTSYALRGGRSPAQ
MUL_4481|M.ulcerans_Agy99 VAEQFALLEAAAPGRIDLGIGR--------APGSDPVTSYALRGGRSPAQ
MAV_1409|M.avium_104 VAEQFALLEAAAPGRIDLGIGR--------APGSDPVTSYALRGGRG---
Mflv_2237|M.gilvum_PYR-GCK VAEQFALLEAAHPGRIDLGIGR--------APGSDPVTSLALRGAAG--R
Mvan_4458|M.vanbaalenii_PYR-1 VAEQFALLEAAHPGRIDLGIGR--------APGSDPVTSLALRGAAG--R
MSMEG_5029|M.smegmatis_MC2_155 VAEQFALLEAAHPGRIDLGIGR--------APGSDPVTSLALRGAAG--R
MLBr_01106|M.leprae_Br4923 ERASFNYTRSVSRARIDLG-------------------------------
Rv3618|M.tuberculosis_H37Rv VADRWVLLDHLTRGRVMFGTGPGALPSDAYMMGIDPVEQRRMMQESLEAI
Mb1971|M.bovis_AF2122/97 LAHRVAYFDHLAQGRFMLGVGASGIPGDWALYDVDGKNGEHREMTREALE
*. :*
MAB_3639|M.abscessus_ATCC_1997 ---DAEHFPQDVLELQAFLGDQ---SRVPG--------VTATPGHGTQVP
TH_4411|M.thermoresistible__bu ---EPQDFARNIYDLQGWFSDTGTAHSMPI--------VSAVS-AGTRVP
MMAR_4179|M.marinum_M QERDIESFPDYLDDVVALMSARGVRVPLQ----SGDYILKATPAALTQPR
MUL_4481|M.ulcerans_Agy99 QERDIESFPDYLDDVVALMSARGARVPLQ----SGDYILKATSAALTQPR
MAV_1409|M.avium_104 -DEDIQRFPDYLDDVAALMSARGVVVPLR----SGDYRLRATPAAAGEPR
Mflv_2237|M.gilvum_PYR-GCK DDRDIEAFPEYLDDVMALMSSKGVRVPLPRDLMRDNYILKATPAAASTPR
Mvan_4458|M.vanbaalenii_PYR-1 DERDIEAFPQYLDDVVALMSSKGVRVPLPRDLMRDNYILKATPAAVTEPR
MSMEG_5029|M.smegmatis_MC2_155 DDRDIEAFPQYLDDVVALMGARGVRVPLPRDLLRDNYILKATPNATSVPQ
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv LALFRAAPDERIDRHSDWFTLREAQLHIRP-------YTWPYPEIATAAM
Mb1971|M.bovis_AF2122/97 IMLRIWTEDEPWEHRGKYWNANGIAPMFEG-----LMRRHIKPYQKPHPP
MAB_3639|M.abscessus_ATCC_1997 LYILGSSLFGAKLAAVLG---LPYGFASHFAPPALQDAVALYRREFQ---
TH_4411|M.thermoresistible__bu IWVLGSTVNGAAIAAQLG---LPFAVASHFAPDQLDAALRTYREMFSTEA
MMAR_4179|M.marinum_M LWLLGSSMYSARLAAAKG---LPYVFAHHFSGKGTEEALELYRSRFV---
MUL_4481|M.ulcerans_Agy99 LWLLGSSMYSARLAAAKG---LPYVFAHHFSGKGTEEALELYRSRFV---
MAV_1409|M.avium_104 LWLLGSSMYSAHLAAAKG---LPYVFAHHFSGKGTEEALEVYRSRFR---
Mflv_2237|M.gilvum_PYR-GCK LWLLGSSMYSARLAAAKG---LPYVFAHHFAGQGTAEALALYRENFQ---
Mvan_4458|M.vanbaalenii_PYR-1 LWLLGSSMYSAQLAAAKG---LPYVFAHHFAGQGTEEALQYYRDNFR---
MSMEG_5029|M.smegmatis_MC2_155 LWLLGSSMYSAHLAAAKG---LPYVFAHHFSGHGTAEALAIYREEFQ---
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv ISPSGPRLAGALGTSLLS---LSMSVPGGYAALETAWGVVREQAAKAG--
Mb1971|M.bovis_AF2122/97 IGVTGFSAGSETLKLAGERGYIPMSLDLNTEYVATHWDAVEEGALRS---
MAB_3639|M.abscessus_ATCC_1997 PSQQLDAPYVLAGVNVIAADDEATARDQHQAALI-ERAKLFLHRSGG-PR
TH_4411|M.thermoresistible__bu PTAQIDRPRVMAGINVMVADTDEEAR--RQFTVV-EQMFLDLKHNLR-RK
MMAR_4179|M.marinum_M PSALAARPVTFLTVNAAVADTREEATALMMPNLH-MMARLRTGQPLGAVQ
MUL_4481|M.ulcerans_Agy99 PSALAARPVTFLTVNAAVADTREEATALMMPNLH-MMARLRTGQPLGPVQ
MAV_1409|M.avium_104 PSALTPEPLTFLTVNAVVAETRDEATALMLPNLQ-MMAKLRTGQPLGPVP
Mflv_2237|M.gilvum_PYR-GCK PSEQTPEPVTFLTVNAVVAESHDEAMRLVLPNLH-MMARLRTGQPLVPLD
Mvan_4458|M.vanbaalenii_PYR-1 PSDLTPEPVTFLTVNAAVAETHDDAMRLILPNLQ-MMARLRTGQPMVPID
MSMEG_5029|M.smegmatis_MC2_155 PSEAAPEPVTFLTVNAVVAETTEEAEALLLPQLQ-MMARLRTGQPLNALD
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv -RGEPDRADWRVLSIMHLSDSRDQAIDDCTYGLP-DFSRYFGAAGFVPLA
Mb1971|M.bovis_AF2122/97 -GRTPDRRDWRLVREVLVAETDEQAFRYAVDGTMGRAMREYVLPTFRMFG
MAB_3639|M.abscessus_ATCC_1997 LTDEEALAALESPAGRQIQSMTK-YFAVGTADQVGAYLEDFAQLAD----
TH_4411|M.thermoresistible__bu IQPPVDPDTLAAQGG-GNEPMLR-IKAVGSPPTVKAQLDEFVARTG----
MMAR_4179|M.marinum_M LVEEAQDARLTPEQQRIVDSGLE-RAVVGSPEEAAEQVRALGQRFG----
MUL_4481|M.ulcerans_Agy99 LVEEAQDARLTPEQQRIVDSGLE-RAVVGSPEEAAEQVRALGQRFG----
MAV_1409|M.avium_104 LVEDAEHAELTAEQRRIVDSGLR-RAVLGGPAEAAEQVRALAERFG----
Mflv_2237|M.gilvum_PYR-GCK LVEDAEALDLGPRAQAVIDGGRN-LAVAGAPAEAADQLLSLAEEFG----
Mvan_4458|M.vanbaalenii_PYR-1 LVEDAEAQVVSPRAQAVIDAGLR-QAVVGSPAEAGDQLRALAEKFG----
MSMEG_5029|M.smegmatis_MC2_155 LVEDAQTTVLTPQGDAVVADGRR-RAVVGSPTEAAEQVRALAEEFD----
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv NTVEGTQSSREFVEQYAAKG----NCCIGTPDDAIAHIEDLLHRSGGFGT
Mb1971|M.bovis_AF2122/97 MTKFYKHNPSVPDDEVTPEYLAENTFVVGSVQTVVDKLEATYDQVGG---
MAB_3639|M.abscessus_ATCC_1997 --------------------ADELIVVPNAPDRK--------LQLRSLEI
TH_4411|M.thermoresistible__bu --------------------ADELITVTYAHDPA--------VRDRSLEL
MMAR_4179|M.marinum_M --------------------VDEVMVHPVASAHRGTDPATAPARVATCEL
MUL_4481|M.ulcerans_Agy99 --------------------VDEVMVHPVASAHRGTGPATAPARVATCEL
MAV_1409|M.avium_104 --------------------VDEVMVNPVASARRGTDPATAPARVATLEL
Mflv_2237|M.gilvum_PYR-GCK --------------------VDEVMVNPVASAYRGVDPATAPAREATLEL
Mvan_4458|M.vanbaalenii_PYR-1 --------------------VDEVMVHPVASAFRGVDPATAPAREATLEL
MSMEG_5029|M.smegmatis_MC2_155 --------------------VDEVMINPVASAHRGADPRTATARDTTLEL
MLBr_01106|M.leprae_Br4923 --------------------------------------------------
Rv3618|M.tuberculosis_H37Rv LLLLGHDWAPPPATFHSYELFARAVIPYFKGQLAAPRASHEWARGKRDQL
Mb1971|M.bovis_AF2122/97 --------------------FGHLLILGFDYSDN-PGPWKESLRLLAHEV
MAB_3639|M.abscessus_ATCC_1997 VAEVSGLTLRG-------------
TH_4411|M.thermoresistible__bu LAKAWF------------------
MMAR_4179|M.marinum_M LAKELF------------------
MUL_4481|M.ulcerans_Agy99 LAKELF------------------
MAV_1409|M.avium_104 LAKELF------------------
Mflv_2237|M.gilvum_PYR-GCK LAKELF------------------
Mvan_4458|M.vanbaalenii_PYR-1 LAKEIF------------------
MSMEG_5029|M.smegmatis_MC2_155 LAKELF------------------
MLBr_01106|M.leprae_Br4923 ------------------------
Rv3618|M.tuberculosis_H37Rv IGRAGEAVVKAITEHVAEQGEAGS
Mb1971|M.bovis_AF2122/97 MPRLNARLATKPATAVV-------