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TTSITLVAPRRFDIVDTVEAALGDARDPDNPAGFAVLAAQDRDDTFPADAIAILDRLRVAEHYVPVADGG RLADYLEVSQLIRVLARRSVTLAVAHAKTFLGAATAWIGARGEQRARLSELVRSGVPVSWGLTEREHGSD LLAGDVAVENGALSGAKWLINNATRGGAVVAIARTSVAGGPRGFDLVLVDKAALSARGAAPTYRHLPKEL THGIRGADISGIEFDGVPVDDTDVLSEPGRGLENVMKALQLTRTLCCSLSVGAAERGLHTAVSFAESREL YGRKLIELPQARRVLTDALADHLLNEVTTCAAIRSIHTLPAELSLHAAAAKYWVPTRTEALLAALRSFVG ARAVLDSDDPTAPALSRIERDHRIVSLFDGNTVVNLTTLITQFPVIGRGDLPADSAALVAAAPDADLSRL SLMSRSGSTLLRTLGDAVIQLDGHDLPDGCRRTASALAAVARDIVRAAADAPRNPAETPNASFALAERLA AAIAGAAAVHVYLAYAGTIDSPLWRDGLWLRLALPRALAGADPAAPPSGPDGDHDAAIAALESLNRSDAG FSVLANVLDDETGDRV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3578c | - | - | 100% (577) | acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3577c | - | 1e-40 | 30.37% (540) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3481 | - | 3e-16 | 22.92% (384) | acyl-CoA dehydrogenase FadE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3302c | fadE25 | 4e-17 | 23.66% (355) | acyl-CoA dehydrogenase FADE25 |
| M. gilvum PYR-GCK | Mflv_0446 | - | 4e-15 | 29.20% (250) | butyryl-CoA dehydrogenase |
| M. tuberculosis H37Rv | Rv3274c | fadE25 | 4e-17 | 23.66% (355) | acyl-CoA dehydrogenase FADE25 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 1e-17 | 24.72% (352) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_1262 | fadE25 | 9e-16 | 23.14% (350) | acyl-CoA dehydrogenase FadE25 |
| M. avium 104 | MAV_4243 | - | 8e-15 | 24.05% (262) | acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1821 | - | 1e-14 | 22.44% (352) | acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3846 | - | 1e-16 | 23.80% (353) | PUTATIVE acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_2626 | fadE25 | 4e-16 | 23.14% (350) | acyl-CoA dehydrogenase FadE25 |
| M. vanbaalenii PYR-1 | Mvan_1719 | - | 1e-16 | 22.86% (350) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1262|M.marinum_M MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
MUL_2626|M.ulcerans_Agy99 MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
Mvan_1719|M.vanbaalenii_PYR-1 MASWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
MSMEG_1821|M.smegmatis_MC2_155 MAAWGGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENARFPQE
MAV_4243|M.avium_104 MAGWAGNPDFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
Mb3302c|M.bovis_AF2122/97 MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
Rv3274c|M.tuberculosis_H37Rv MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
TH_3846|M.thermoresistible__bu MAAWSGNPSFELFQLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEE
Mflv_0446|M.gilvum_PYR-GCK MVDG----------LSSEEAMLVQTVRAFIDRDVKPTVRDVEHANTYPEA
MAB_3578c|M.abscessus_ATCC_199 MTTSITLVAPRRFDIVDTVEAALGDARDPDNPAGFAVLAAQDRDDTFPAD
*. : . * : . :. :*
MMAR_1262|M.marinum_M ALDALNASGFNAVHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
MUL_2626|M.ulcerans_Agy99 ALDALNASGFNALHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
Mvan_1719|M.vanbaalenii_PYR-1 ALDALNASGFNAVHVPEEFGGQGADSVAACIVIEEVARVDASASLIPAVN
MSMEG_1821|M.smegmatis_MC2_155 ALDALNASGFNAVHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
MAV_4243|M.avium_104 ALEALNAAGFNAVHVPEEYGGQGADSVAACIVIEEVARVDTSASLIPAVN
Mb3302c|M.bovis_AF2122/97 ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN
Rv3274c|M.tuberculosis_H37Rv ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
TH_3846|M.thermoresistible__bu ALAALNSSGFSAIHVPEEYGGQGADSVATCIVIEEVARVDCSASLIPAVN
Mflv_0446|M.gilvum_PYR-GCK WIDQMKQIGIYGLAVPESYGGTPVSTRCYVLVTQELARGWMSLAGAMGGH
MAB_3578c|M.abscessus_ATCC_199 AIAILDRLRVAEHYVPVADGGRLADYLEVSQLIRVLARRSVTLAVAHAKT
: :. . :* ** .. : . :** : : .
MMAR_1262|M.marinum_M KLGTMGLILRGSDDLKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA
MUL_2626|M.ulcerans_Agy99 KLGTMGLILRGSDELKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA
Mvan_1719|M.vanbaalenii_PYR-1 KLGTMGLILRGSDELKKKVLPSIASGEAMASYALSEREAGSDAAAMRTRA
MSMEG_1821|M.smegmatis_MC2_155 KLGTMGLILRGSDELKKQVLPQLASGAAMASYALSEREAGSDAASMRTRA
MAV_4243|M.avium_104 KLGTMGLILRGSDELKKQVLPSIADGSAMASYALSEREAGSDAASMRTRA
Mb3302c|M.bovis_AF2122/97 KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA
Rv3274c|M.tuberculosis_H37Rv KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA
MLBr_00737|M.leprae_Br4923 KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
TH_3846|M.thermoresistible__bu KLGTMGLILRGSEELKKQVLPAVASGEAMASYALSEREAGSDAASMRTRA
Mflv_0446|M.gilvum_PYR-GCK TVVAKLLTLFGTEEQKQRYLPAMATGEIRATMALTEPGGGSDLQAMGTVA
MAB_3578c|M.abscessus_ATCC_199 FLGAATAWIGARGE-QRARLSELVRSGVPVSWGLTEREHGSDLLAGDVAV
: : : . : :: *. :. .: .*:* *** : . .
MMAR_1262|M.marinum_M KADGDDWILNGTKCWITNGGKSSWYTVMAVTDPEKG--ANGISAFMVHKD
MUL_2626|M.ulcerans_Agy99 KADGDDWILNGTKCWITNGGKSSWYTVMAVTDPENG--ANGISAFVVHKD
Mvan_1719|M.vanbaalenii_PYR-1 KADGDDWILNGAKCWITNGGKSSWYTVMAVTDPDKG--ANGISAFMVHID
MSMEG_1821|M.smegmatis_MC2_155 RADGDDWVLNGTKCWITNGGKSSWYTVMAVTDPDKG--ANGISAFMVHQD
MAV_4243|M.avium_104 RADGDDWILNGAKCWITNGGKSSWYTVMAVTDPDKG--ANGISSFMVHKD
Mb3302c|M.bovis_AF2122/97 KADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRG--ANGISAFMVHKD
Rv3274c|M.tuberculosis_H37Rv KADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRG--ANGISAFMVHKD
MLBr_00737|M.leprae_Br4923 KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKG--ANGISAFIVHKD
TH_3846|M.thermoresistible__bu VADGDDWILNGSKCWITNGGKSTWYTVMAVTDPDKG--ANGISAFMVHKD
Mflv_0446|M.gilvum_PYR-GCK RRDGDDLVLSGTKTWISNARRSGLIALLCKTDPDATPKHSGISVVLVDNP
MAB_3578c|M.abscessus_ATCC_199 ENG----ALSGAKWLINNATRGGAVVAIARTSVAGG--PRGFDLVLVDKA
. *.* * *.*. :. . :. *. *:. .:*.
MMAR_1262|M.marinum_M -------DEGFVVGPKERKLGIKGSPTTELYFENCRVPGDRMIG-EPGTG
MUL_2626|M.ulcerans_Agy99 -------DEGFVVGPKERKLGIKGSPTTELYFENCRVPGDRMIG-EPGTG
Mvan_1719|M.vanbaalenii_PYR-1 -------DEGFTIGPKERKLGIKGSPTTELYFENCRIPGDRIIG-EPGTG
MSMEG_1821|M.smegmatis_MC2_155 -------DEGFSVGPKERKLGIKGSPTTELYFENCRIPGDRIIG-EPGTG
MAV_4243|M.avium_104 -------DEGFTVGPKEKKLGIKGSPTTELYFENCRIPGDRIIG-EPGTG
Mb3302c|M.bovis_AF2122/97 -------DEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIG-EPGTG
Rv3274c|M.tuberculosis_H37Rv -------DEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIG-EPGTG
MLBr_00737|M.leprae_Br4923 -------DEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIG-EPGTG
TH_3846|M.thermoresistible__bu -------DEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIG-EPGTG
Mflv_0446|M.gilvum_PYR-GCK -------TPGLTVSRDLPKLGYKGVESCELAFDACRVPASAILGGTPGKG
MAB_3578c|M.abscessus_ATCC_199 ALSARGAAPTYRHLPKELTHGIRGADISGIEFDGVPVDDTDVLS-EPGRG
. . * :* : *: : ::. ** *
MMAR_1262|M.marinum_M FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGKSISDFQAV
MUL_2626|M.ulcerans_Agy99 FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGKSISDFQAV
Mvan_1719|M.vanbaalenii_PYR-1 FKTALATLDHTRPTIGAQAVGIAQGALDASLEYVKDRKQFGKSISEFQAV
MSMEG_1821|M.smegmatis_MC2_155 FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGTSISDFQAV
MAV_4243|M.avium_104 FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGV
Mb3302c|M.bovis_AF2122/97 FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAV
Rv3274c|M.tuberculosis_H37Rv FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAV
MLBr_00737|M.leprae_Br4923 FKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSI
TH_3846|M.thermoresistible__bu FKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGV
Mflv_0446|M.gilvum_PYR-GCK FSQMMKGLETGRIQVASRALGVASAALEDALAYAQDRESFGRPIWKHQAV
MAB_3578c|M.abscessus_ATCC_199 LENVMKALQLTRTLCCSLSVGAAERGLHTAVSFAESRELYGRKLIELPQA
:. : *: * : ::* *. .*. :: :.:.*: :* :
MMAR_1262|M.marinum_M QFMLADMAMKVESARLMVYSAAARAERGESNLGFISAASKCLASDVAMEV
MUL_2626|M.ulcerans_Agy99 QFMLADMAMKVESARLMVYSAAARAERGESNLGFISAASKCLASDVAMEV
Mvan_1719|M.vanbaalenii_PYR-1 QFMLADMAMKVEAARLMVYSAAARAERGEGNLGFISAASKCLASDVAMEV
MSMEG_1821|M.smegmatis_MC2_155 QFMLADMAMKVESARLMVYHAAARAERGEKNLGFISAASKCLASDIAMEV
MAV_4243|M.avium_104 QFMLADMAMKVESARLMVYHAAARAERGESHLGFISAASKCLASDVAMEV
Mb3302c|M.bovis_AF2122/97 QFMLADMAMKVEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEV
Rv3274c|M.tuberculosis_H37Rv QFMLADMAMKVEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEV
MLBr_00737|M.leprae_Br4923 QFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEV
TH_3846|M.thermoresistible__bu QFMLADMAMKIEAARLMVYSAAARAERGEGDLGFISAASKCFASDVAMEV
Mflv_0446|M.gilvum_PYR-GCK GHYLADMATKLTAARQLTLYAADRYDSGE-RADMEAGMAKLFASEVAMEI
MAB_3578c|M.abscessus_ATCC_199 RRVLTDALADHLLNEVTTCAAIRSIHTLPAELSLHAAAAKYWVPTRTEAL
*:* . . . * . .: :. :* .. : :
MMAR_1262|M.marinum_M TTDAVQLFGG-----AGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSR
MUL_2626|M.ulcerans_Agy99 TTDAVQLFGG-----AGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSR
Mvan_1719|M.vanbaalenii_PYR-1 TTDAVQLFGG-----AGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSR
MSMEG_1821|M.smegmatis_MC2_155 TTDAVQLFGG-----AGYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSR
MAV_4243|M.avium_104 TTDAVQLFGG-----YGYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSR
Mb3302c|M.bovis_AF2122/97 TTDAVQLFGG-----AGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSR
Rv3274c|M.tuberculosis_H37Rv TTDAVQLFGG-----AGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSR
MLBr_00737|M.leprae_Br4923 TTDAVQLFGG-----AGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSR
TH_3846|M.thermoresistible__bu TTDAVQLFGG-----YGYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSR
Mflv_0446|M.gilvum_PYR-GCK ALNAVRIHGG-----YGYSTEYDVERYFRDAPLMIVGEGTNEIQRNVIAG
MAB_3578c|M.abscessus_ATCC_199 LAALRSFVGARAVLDSDDPTAPALSRIERDHRIVSLFDGNTVVNLTTLIT
: *. . . :.* ** : : :*.. :: .:
MMAR_1262|M.marinum_M ALLR----------------------------------------------
MUL_2626|M.ulcerans_Agy99 ALLR----------------------------------------------
Mvan_1719|M.vanbaalenii_PYR-1 ALLK----------------------------------------------
MSMEG_1821|M.smegmatis_MC2_155 ALLR----------------------------------------------
MAV_4243|M.avium_104 ALLR----------------------------------------------
Mb3302c|M.bovis_AF2122/97 ALLR----------------------------------------------
Rv3274c|M.tuberculosis_H37Rv ALLR----------------------------------------------
MLBr_00737|M.leprae_Br4923 ALLR----------------------------------------------
TH_3846|M.thermoresistible__bu ALLR----------------------------------------------
Mflv_0446|M.gilvum_PYR-GCK QLVARGGI------------------------------------------
MAB_3578c|M.abscessus_ATCC_199 QFPVIGRGDLPADSAALVAAAPDADLSRLSLMSRSGSTLLRTLGDAVIQL
:
MMAR_1262|M.marinum_M --------------------------------------------------
MUL_2626|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1719|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1821|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4243|M.avium_104 --------------------------------------------------
Mb3302c|M.bovis_AF2122/97 --------------------------------------------------
Rv3274c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_3846|M.thermoresistible__bu --------------------------------------------------
Mflv_0446|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3578c|M.abscessus_ATCC_199 DGHDLPDGCRRTASALAAVARDIVRAAADAPRNPAETPNASFALAERLAA
MMAR_1262|M.marinum_M --------------------------------------------------
MUL_2626|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1719|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1821|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4243|M.avium_104 --------------------------------------------------
Mb3302c|M.bovis_AF2122/97 --------------------------------------------------
Rv3274c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
TH_3846|M.thermoresistible__bu --------------------------------------------------
Mflv_0446|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3578c|M.abscessus_ATCC_199 AIAGAAAVHVYLAYAGTIDSPLWRDGLWLRLALPRALAGADPAAPPSGPD
MMAR_1262|M.marinum_M -----------------------------------
MUL_2626|M.ulcerans_Agy99 -----------------------------------
Mvan_1719|M.vanbaalenii_PYR-1 -----------------------------------
MSMEG_1821|M.smegmatis_MC2_155 -----------------------------------
MAV_4243|M.avium_104 -----------------------------------
Mb3302c|M.bovis_AF2122/97 -----------------------------------
Rv3274c|M.tuberculosis_H37Rv -----------------------------------
MLBr_00737|M.leprae_Br4923 -----------------------------------
TH_3846|M.thermoresistible__bu -----------------------------------
Mflv_0446|M.gilvum_PYR-GCK -----------------------------------
MAB_3578c|M.abscessus_ATCC_199 GDHDAAIAALESLNRSDAGFSVLANVLDDETGDRV