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MYSFGKQLAALPRSQYGPWAVIAAGDTDTATAFARHIAANGINIVLAAHGGRADAYTLTMTAGVSVRTTS PDVFNGELAAATDDIEVGLLVCITDEDAGGSRFGESDLNRLRTLYLTHRFGQRIASRGEGAVIMVKSLAA QSISNSSLTGNADSAFTTGIHDGLHQQGVEVVLLDDFVPHRPAMDADDLSLMALARLGRRRHRHCSHENE LTTPPPVLRAN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3480 | - | - | 100% (221) | putative short chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4545 | - | 2e-16 | 32.16% (199) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3509 | - | 5e-07 | 28.74% (167) | short-chain alcohol dehydrogenase |
| M. avium 104 | MAV_5238 | - | 1e-10 | 25.25% (198) | oxidoreductase, short-chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_2895 | - | 3e-13 | 31.09% (193) | short chain oxidoreductase |
| M. thermoresistible (build 8) | TH_2749 | - | 1e-09 | 28.57% (196) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2633 | - | 1e-12 | 30.30% (198) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4545|M.gilvum_PYR-GCK ---------------MTKYGPWAVIAGGSEGVGAEFAKALAEDGANLVLI
MMAR_3509|M.marinum_M -----------------------------------------------MLI
MSMEG_2895|M.smegmatis_MC2_155 ------------MPDLATYGPWAVIAGGSEGVGAEFARLLAEAGVNLVLI
TH_2749|M.thermoresistible__bu ------------VTDLTRYGPTAVIAGGSEGVGAEFARLLADAGIDLVLI
Mvan_2633|M.vanbaalenii_PYR-1 MLPDTRRGDDVTVTDLTGYGPWAVVAGGSEGVGAEFAAQLARAGVNLVLV
MAV_5238|M.avium_104 ------------MSFAARYGPWALVAGASDGVGAAFAEGLAERGVNVALL
MAB_3480|M.abscessus_ATCC_1997 ---MYSFGKQLAALPRSQYGPWAVIAAGDTDTATAFARHIAANGINIVLA
*
Mflv_4545|M.gilvum_PYR-GCK ARKPQPLDETAQECRRLG-AQVRTIALDLLDADSTSRIVDATSDVEVGLL
MMAR_3509|M.marinum_M ARAPGPLADTARRCRETG-VHVRTIAVDLVDPEAVALICSETADLEVGLL
MSMEG_2895|M.smegmatis_MC2_155 ARKPGPLQDTAQRCREIG-VDVRTVATDLLDPTAVEQITGATAGLDVGLL
TH_2749|M.thermoresistible__bu ARKPGPLEDTAADCRARG-VEVRTISADLTDPAAVHRVLAECAGLEVGLL
Mvan_2633|M.vanbaalenii_PYR-1 ARTPEPLERTAARCREFG-VQTRTLAVDLVD--ATHEVIAATADLEVGLL
MAV_5238|M.avium_104 ARRQDVLDRVAARIRARTSAQTRTLAIDLAHPGAAKAIAAATADVTIGML
MAB_3480|M.abscessus_ATCC_1997 AHGG---RADAYTLTMTAGVSVRTTSPDVFN----GELAAATDDIEVGLL
*: * . .** : *: . : .: :*:*
Mflv_4545|M.gilvum_PYR-GCK IYNAGASTCNERFLDAELSEFGKVIDLNTTRMLELTQHFGRRMAAMSRGG
MMAR_3509|M.marinum_M IYNAGANTCREQFLDAELTELGRVIDLNVTRMLELVQHFGRPMRARRRGG
MSMEG_2895|M.smegmatis_MC2_155 IYNAGASTCNEPFLDAPLDDFRKVLDLNVTRMMELVQHYARPMVARQRGG
TH_2749|M.thermoresistible__bu IYNAGANTCSEEFLDGELADFDKVLRLNIDTMLTLVQHFGRPMRERRSGG
Mvan_2633|M.vanbaalenii_PYR-1 IYNAGANTCSEEFLDADLAEFGRVVDLNVTAMMTLVQHYGRPMRERRRGG
MAV_5238|M.avium_104 VYCAGADPDFKPFLANRIEAAEAMVQRNCMVPMQLCHHYAPAMVERGAGG
MAB_3480|M.abscessus_ATCC_1997 VCITDEDAGGSRFGES---------DLNRLRTLYLTHRFGQRIASRGEGA
: :. .. . * * : * :::. : *.
Mflv_4545|M.gilvum_PYR-GCK IVLVGSLSGYMGAERHSVYAGAKAFSRVFAESLWLELREHGVDVLELVLG
MMAR_3509|M.marinum_M IVLVGSTAATYGAMRQSAYAGAKAFSRLFAESLWLELRETGVDVLELVLG
MSMEG_2895|M.smegmatis_MC2_155 VLIVGSLSGYMGADRHSVYGGAKAFSRIFAESLWLELREHNVDVVELVLG
TH_2749|M.thermoresistible__bu ILLVGSMAGYLGSARHTVYGGVKAFGRIFAESLWLELRDHGVDVLELVLG
Mvan_2633|M.vanbaalenii_PYR-1 ILLVGSMAGYLGSVRHTVYGGVKAFGRIFAEGLWLELRDHDVHVLELVLG
MAV_5238|M.avium_104 IVLFGSGAGLAGGPNMVAYGASKAFDMVFAEALWAELHDKGVDVLGLILG
MAB_3480|M.abscessus_ATCC_1997 VIMVKSLAAQSISNSSLTGNADSAFT----TGIHDGLHQQGVEVVLLDDF
:::. * :. . . . .** .: *:: .*.*: *
Mflv_4545|M.gilvum_PYR-GCK VTRTPAMERAGLN---FDAPGIIVNDPA---DVAREGLRHIADGPVFIAG
MMAR_3509|M.marinum_M VTRTPAMQRAGLN---FDAPGISVSDPA---DVAREGLDNLANGPVVIAG
MSMEG_2895|M.smegmatis_MC2_155 VTRTPAMERVGLN---FDVPGMIVNDPA---DVAAEGLANLANGPVHIAG
TH_2749|M.thermoresistible__bu VTRTPAMERAGLN---FDVPGLRVADPA---DVAREGLERLPHGPVHVAG
Mvan_2633|M.vanbaalenii_PYR-1 VTRTPAMERVGLN---FDVPGLRVSEPA---EVAAEGLRQLPHGPVHVVN
MAV_5238|M.avium_104 KTDTPALRALEYSRGQIASPDQAPSDAAAVSDVIAEAFENLGNGPTLMVG
MAB_3480|M.abscessus_ATCC_1997 VPHRPAMDADDLS------------------------LMALAR-----LG
. **: . : : .
Mflv_4545|M.gilvum_PYR-GCK GNAERAARSSA-PDRAAVVLGSHEMIKRLRGMRP--------
MMAR_3509|M.marinum_M DNAAHVHRGSG-ADRAAIVLRAHRAMQALIGSPPPPPKGDRA
MSMEG_2895|M.smegmatis_MC2_155 GNAAIAAANNA-PDRAKVVLQAHERMRRLINRGA--------
TH_2749|M.thermoresistible__bu GNAEDVARRND-PDRAKVVLGAHRFVQKLIGQA---------
Mvan_2633|M.vanbaalenii_PYR-1 GNEDDVARRND-PDRARVVLGAHRFMQKLIGGRGHR------
MAV_5238|M.avium_104 DTMRAAAQLLASLSRNQAVELFAQAAAAAMGPDD--------
MAB_3480|M.abscessus_ATCC_1997 RRRHRHCSHENELTTPPPVLRAN-------------------
*