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ASAPLRVVTNNGEVEGFVRRGMRRFRGIPYAEPPVGPLRLRAPRPAQPWEGVRRCKRFGAAPYQPKIFTP QKQRSEDCLTLNVVAPEQLPDGPLPVMFYIYGGGYFLGSSSSPPYEGSILARRGCVYVSANYRVGAFGAF DLSSLSDDRHVIESNLYLRDLVLALQWVRENIAAFGGDPENVTIFGESAGGSGVETLMATPAAAGLFHKA IIQSTASGLAADADSVAYDARRFAEILGATSDNAAATVLNASPRQLLRAQRKLIAEGGFPFGPSVDGNYL PKKPVESIEGGEAHRVPLIIGSNADEAKLFTKAIKVMPLSEAEQLEILGRGGPGYQERITAAYVGYPSMQ ARLRLAGDMFFTSSVWRIAQAHQHFAPVYVYQFDYAPWPVRAAGLEGSHATELLAVFGNYRGPAGPILTG SFTHRDASRVVDDVQQRWVAFARNGVPSGDWPPYRGPDWPVLVFDRELRVEQNLGGDRRTVWDGFRLSIP SRIPRAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3336c | - | - | 100% (498) | carboxylesterase LipT |
| M. abscessus ATCC 19977 | MAB_3453c | - | e-173 | 60.56% (497) | carboxylesterase LipT |
| M. abscessus ATCC 19977 | MAB_3452c | - | e-163 | 57.98% (495) | carboxylesterase LipT |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2071c | lipT | 1e-139 | 51.00% (500) | carboxylesterase LipT |
| M. gilvum PYR-GCK | Mflv_3125 | - | 1e-144 | 52.10% (499) | carboxylesterase, type B |
| M. tuberculosis H37Rv | Rv2045c | lipT | 1e-139 | 51.00% (500) | carboxylesterase LipT |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3020 | lipT | 1e-136 | 49.80% (500) | carboxylesterase, LipT |
| M. avium 104 | MAV_2466 | - | 1e-145 | 53.17% (504) | LppT protein |
| M. smegmatis MC2 155 | MSMEG_3848 | - | 1e-142 | 51.20% (500) | para-nitrobenzyl esterase |
| M. thermoresistible (build 8) | TH_0737 | lipT | 1e-147 | 53.71% (499) | Probable carboxylesterase LipT |
| M. ulcerans Agy99 | MUL_2261 | lipT | 1e-135 | 49.60% (500) | carboxylesterase, LipT |
| M. vanbaalenii PYR-1 | Mvan_3408 | - | 1e-139 | 50.50% (497) | carboxylesterase, type B |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0737|M.thermoresistible__bu -------------VMHEHRVRVQISTGTIEGFTRDGVHRWRAIPYAKPPV
Mvan_3408|M.vanbaalenii_PYR-1 --------------MHEHTVRVRTASGTVEGFTRDGVHRWRSIPYARPPV
MSMEG_3848|M.smegmatis_MC2_155 --------------MHERTVRAEISTGIIEGFTRDGVHRWRSIPYARAPI
Mb2071c|M.bovis_AF2122/97 ----MALESATVGSMHERTVRARTATGIVEGFTRDGVHRWRSIPYARAPV
Rv2045c|M.tuberculosis_H37Rv ----MALESATVGSMHERTVRARTATGIVEGFTRDGVHRWRSIPYARAPV
MMAR_3020|M.marinum_M --------------MHERTVRARTATGIVEGFTRDGVHRWRSIPYARAPI
MUL_2261|M.ulcerans_Agy99 --------------MHERTVRARTATGVVEGFTRDGVHRWRSIPYARAPI
MAV_2466|M.avium_104 --------------MHDRTVRARTATGIVEGFTRDGVHRWRSIPYARPPV
Mflv_3125|M.gilvum_PYR-GCK MVRQAGREFDTVGRMHEHTVRVKIASGTVEGFTRDGVHRWRSIPYARPPV
MAB_3336c|M.abscessus_ATCC_199 --------------MASAPLRVVTNNGEVEGFVRRGMRRFRGIPYAEPPV
* . :*. .* :***.* *::*:*.****..*:
TH_0737|M.thermoresistible__bu GPLRLRAPEPADPWPGVRHCHGFGNCAPQERKYTLIGLG----KYQPMGE
Mvan_3408|M.vanbaalenii_PYR-1 GRLRYRAPEPVQPWSGVRHCHGFLSCAPQHRRYTLIGVR----KYQPTSE
MSMEG_3848|M.smegmatis_MC2_155 GPLRLRAPQPAEPWPGVRYCHGFGFCAPQQRRYTLLGVG----KYQPTSE
Mb2071c|M.bovis_AF2122/97 GSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRYTVMGIG----RYQTRSE
Rv2045c|M.tuberculosis_H37Rv GSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRYTVMGIG----RYQTRSE
MMAR_3020|M.marinum_M GPLRFRAPRPPQPWSGVRHCHGFTHCSPQQRRYTMLGLG----KYQPMSE
MUL_2261|M.ulcerans_Agy99 GLLRFRAPRPPQPWSGVRHCHGFTHCSPQQRRYTMLGLG----KYQPMSE
MAV_2466|M.avium_104 GDLRFRAPQPAQPWSGVRHCHGFANCAPQQRRYTLLGLSGLGGRYQPMSE
Mflv_3125|M.gilvum_PYR-GCK GPLRYRAPRPVQPWPGVRYCHGFGACAPQQRMYTLLAPG----RYQPMSE
MAB_3336c|M.abscessus_ATCC_199 GPLRLRAPRPAQPWEGVRRCKRFGAAPYQPKIFTPQKQR---------SE
* ** ***.* :** *** *: * .. * : :* .*
TH_0737|M.thermoresistible__bu DCLTLNVVAPEHPPDS----PMPVLVFIHGGGYLLGSSATPIYDGAALAR
Mvan_3408|M.vanbaalenii_PYR-1 DCLTLNVVAPEGAASAGE--PLPVMFFIHGGGYILGSSATPLYDGAALAR
MSMEG_3848|M.smegmatis_MC2_155 DCLTLNVVAPEKPHDG----PLPVMFFVHGGGYVLGSSATPIYDGAALAR
Mb2071c|M.bovis_AF2122/97 DCLTLNVVTPEEPATQ----PLPVMVFIHGGGYILGSSATPIYDGAALAR
Rv2045c|M.tuberculosis_H37Rv DCLTLNVVTPEEPATQ----PLPVMVFIHGGGYILGSSATPIYDGAALAR
MMAR_3020|M.marinum_M DCLTLNVVAPEAPSHR----PLPVMVFIHGGGYILGSSATPIYDGAALAR
MUL_2261|M.ulcerans_Agy99 DCLTLNVVAPEAPTHR----PLPVMVFIHGGGYILGSSATPIYDGAALAR
MAV_2466|M.avium_104 DCLTLNVVTPEAPAEG----PLPVMVFIHGGGYFLGSSATPLYDGAALAR
Mflv_3125|M.gilvum_PYR-GCK DCLTLNVVAPADAEARAADGPLPVMVFIHGGGYLLGSSATPVYDGASLAR
MAB_3336c|M.abscessus_ATCC_199 DCLTLNVVAPEQLPDG----PLPVMFYIYGGGYFLGSSSSPPYEGSILAR
********:* *:**:.:::****.****::* *:*: ***
TH_0737|M.thermoresistible__bu RGCVYVSVNYRLGALGCMDLSSLSTRRHPIDSNLFLRDLVLALQWVRDNI
Mvan_3408|M.vanbaalenii_PYR-1 RGCVYVSVNYRLGPLGCMDLSSLSTPENPIDDNLFLRDLVMALRWVRDNV
MSMEG_3848|M.smegmatis_MC2_155 RGCVYVSVNYRLGVLGAMELSSLSTPEHPIDDNLFLRDLVLALQWVRDNI
Mb2071c|M.bovis_AF2122/97 RGCVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDLVLALRWVHDNI
Rv2045c|M.tuberculosis_H37Rv RGCVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDLVLALRWVHDNI
MMAR_3020|M.marinum_M RGCVYVSVNYRLGALGCLDLSSLSTPDIAIDGNLYLRDLVMALQWIQDNI
MUL_2261|M.ulcerans_Agy99 RGCVYVSVNYRLGALGCLDLSSLSTPDIAIDGNLYLRDLVMALQWIQDNI
MAV_2466|M.avium_104 RGCVYVSVNYRLGALGCVDFSSLSTPEIPLESNLYLRDLVLALQWVRDNI
Mflv_3125|M.gilvum_PYR-GCK KGCVYISVNYRLGALGCLELSSLSTPEAPIDDNLFLRDLVMALRWVRDNV
MAB_3336c|M.abscessus_ATCC_199 RGCVYVSANYRVGAFGAFDLSSLSDDRHVIESNLYLRDLVLALQWVRENI
:****:*.***:* :*..::**** ::.*::*****:**:*:::*:
TH_0737|M.thermoresistible__bu SVFGGDPGNVTIFGESAGAHAVATLMAVPAAKGLFSQAISQSPASGMVRS
Mvan_3408|M.vanbaalenii_PYR-1 AAFGGDPDKVTIFGESAGAHAVATLLATPQAKGLFAQAISESPASGMVRS
MSMEG_3848|M.smegmatis_MC2_155 AVFGGDPDNVTIFGESAGAHAVATLLAVPAARGLFARVISESPASGMVSS
Mb2071c|M.bovis_AF2122/97 AEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRS
Rv2045c|M.tuberculosis_H37Rv AEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRS
MMAR_3020|M.marinum_M AEFGGDPDNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRP
MUL_2261|M.ulcerans_Agy99 AEFGGDPDNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRP
MAV_2466|M.avium_104 AEFGGDPDNVTIFGESAGACITATLLAVPAAKGLFAQAISESPASGLVRS
Mflv_3125|M.gilvum_PYR-GCK AAFGGDPGNVTIFGESAGAHAVSTLVATPEAEGLFAQAIAQSPASGMISD
MAB_3336c|M.abscessus_ATCC_199 AAFGGDPENVTIFGESAGGSGVETLMATPAAAGLFHKAIIQSTASGLAAD
: ***** :*********. . **:*.* * *** :.* :*.*:*:
TH_0737|M.thermoresistible__bu ADVAAEFARRFADLLG-AGRDPAAALMAASPADLVRALDELISRGMTDMP
Mvan_3408|M.vanbaalenii_PYR-1 TEMAAKFASRFADLVANDGGDAAAALMSASPHALIAALDDLVANGFKDMP
MSMEG_3848|M.smegmatis_MC2_155 ADTAARLAGQYAGIIGHGGRDAAEALKTLSPAQLGRALEELINRGMTDMP
Mb2071c|M.bovis_AF2122/97 REVAAEFAARFANLIGARTQDAANALMQASPAQLVEAQHHLIRQGMRKRL
Rv2045c|M.tuberculosis_H37Rv REVAAEFAARFANLIGARTQDAANALMQASPAQLVEAQHHLIRQGMRKRL
MMAR_3020|M.marinum_M REIAAEFATRFARLLGARKHDAASALMRATAAQLVQTQHRLIDQGMQKRL
MUL_2261|M.ulcerans_Agy99 REIAAEFATRFARLLGARKHDAASALMRATAAQLVQTQHRLIDQGMQKRL
MAV_2466|M.avium_104 QEVAAEFANRFANLLGVRRQDAANALMQASAAQLVKTQHRLIDEGMQDRL
Mflv_3125|M.gilvum_PYR-GCK ADIAADYAQRFARQLGADGKDGARALLAARPADLVDALERLIVEGQRDLV
MAB_3336c|M.abscessus_ATCC_199 ADSVAYDARRFAEILGATSDNAAATVLNASPRQLLRAQRKLIAEG-----
: .* * ::* :. : * :: . * : *: .*
TH_0737|M.thermoresistible__bu GAFAVGPSYGDDCLPRHPVEAMRDGRAHDVPLIVGTNAEEGRLFRRFLPL
Mvan_3408|M.vanbaalenii_PYR-1 GAFPVGPTYGTEYLPKDPVEAMRDGTAHRVPLIVGTNAEEGRLFTRFLPL
MSMEG_3848|M.smegmatis_MC2_155 GAFPVGPTYGTEFLPTDPVEAMAAGSAHRVPLIVGNNAEEGRLFTRFLPL
Mb2071c|M.bovis_AF2122/97 GAFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGTNAEEGRLFTRFLGM
Rv2045c|M.tuberculosis_H37Rv GAFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGTNAEEGRLFTRFLGM
MMAR_3020|M.marinum_M GAFPIGPTFGDDCLPLDPVEAMRAGQSHKVPLIVGTNADEGRLFTRFLKM
MUL_2261|M.ulcerans_Agy99 GAFPIGPTFGDDCLPLDPVEAMRAGQSHKVPLIVGTNADEGRLFTRFLKM
MAV_2466|M.avium_104 GAFPIGPVVGDDILPTDPVEAMRRGEAHRVPLIVGTNAEEGRLFTRFLAM
Mflv_3125|M.gilvum_PYR-GCK GAFAIGPTYGTEYLPEDPVEAMRSGRAHPVPLIVGTNADEGRLFTRFLKL
MAB_3336c|M.abscessus_ATCC_199 -GFPFGPSVDGNYLPKKPVESIEGGEAHRVPLIIGSNADEAKLFTKAIKV
.*..** . : ** .***:: * * ****:*.**:*.:** : : :
TH_0737|M.thermoresistible__bu LPISEPMIEALFGDTDAEVRDRIIAAYPGYPDADACIRLGGDFAFGTAAW
Mvan_3408|M.vanbaalenii_PYR-1 LPTTEQTIEIMLGDTDAEVRNRIMSAYPDYPKPDACVQIGGDFTFSTAAW
MSMEG_3848|M.smegmatis_MC2_155 LPTNEPMIEKLFADADPEHRERILSAYPGYPDRDVCVRLGGDFAFGSATW
Mb2071c|M.bovis_AF2122/97 LPTNEPMVEELLSGMKPADRERITAAYPNYPAPSACIQLGGDFAFSSAAW
Rv2045c|M.tuberculosis_H37Rv LPTNEPMVEELLSGMKPADRERITAAYPNYPAPSACIQLGGDFAFSSAAW
MMAR_3020|M.marinum_M LPTNKAMIDELLADTEPATRERITAAYPNYPESAACIQLGGDFAFNAAAW
MUL_2261|M.ulcerans_Agy99 LPTNKAMIDELLADTEPATRERITAAYPNYPESAACIQLGGDFAFNAAAW
MAV_2466|M.avium_104 LPTNESMVEELLADAEPAVRERITAAYPDYPDRSACIQLGGDFAFGSAAW
Mflv_3125|M.gilvum_PYR-GCK LPTNEQAIEQLLSAVEPEARQRVLAAYPKYPAVDACVAFGGDFIFGSAVW
MAB_3336c|M.abscessus_ATCC_199 MPLSEAEQLEILGRGGPGYQERITAAYVGYPSMQARLRLAGDMFFTSSVW
:* .: ::. . ::*: :** ** . : :.**: * ::.*
TH_0737|M.thermoresistible__bu EISEAHSRHAPTYVYRYDYAPRMLHWSGIGATHATELLAVFGTYRTRPGR
Mvan_3408|M.vanbaalenii_PYR-1 QIGEAHSRHAPTFVYRYDYAPRPLHWSGMGATHATELLAVFDIYRTMPGA
MSMEG_3848|M.smegmatis_MC2_155 QVAEAHSRHAPTYVYRYDYAPRALRWSGLGATHAMELLAVFDTYRTRYGS
Mb2071c|M.bovis_AF2122/97 QIAEAHGANAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFGA
Rv2045c|M.tuberculosis_H37Rv QIAEAHGANAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFGA
MMAR_3020|M.marinum_M QIAEAQGAHAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFGA
MUL_2261|M.ulcerans_Agy99 QIAEAQGVHAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFGA
MAV_2466|M.avium_104 QIAEAHCAHAPTYLYRYDYAPRTLRWSGFGATHATELLAVFDVYRTRFGA
Mflv_3125|M.gilvum_PYR-GCK QIAHAHSAFAPTYVYRYDYATAALRLSGMGATHATELLAVFDVYRSRFGK
MAB_3336c|M.abscessus_ATCC_199 RIAQAHQHFAPVYVYQFDYAPWPVRAAGLEGSHATELLAVFGNYRGPAGP
.:..*: **.::*::***. :: :*: .:** **:***. ** *
TH_0737|M.thermoresistible__bu LLTLAGDWVSAQRVSSDLQRRWLAFGRTGVPGDDWPAYTAEHRPVRVFDR
Mvan_3408|M.vanbaalenii_PYR-1 LLTLAGDWRSARRVSKDVQRRWSSFSRTGVPGADWPRYSAEDRPVMVFDR
MSMEG_3848|M.smegmatis_MC2_155 MLTAMADRRSARRVSRDIQTRWRDFSRAGVPGDGWPAYRHDERAVYVFDT
Mb2071c|M.bovis_AF2122/97 LLTAAADRRAALRVSNEVQRRWRCFSQIGVPGDDWPAYTQDDRAVLVFDR
Rv2045c|M.tuberculosis_H37Rv LLTAAADRRAALRVSNEVQRRWRCFSQIGVPGDDWPAYTQDDRAVLVFDR
MMAR_3020|M.marinum_M LLTAAADRRHALRVSDEVIRRWRSFSQTGTPGEDWPAYTHTRRAVMVIDR
MUL_2261|M.ulcerans_Agy99 LLTAAADRRHALRVSDEVIRRWRSFSQTGTPGEDWPAYTHTRRAVMVIDR
MAV_2466|M.avium_104 LLTAAADRRAALRVSNQVQRRWRAFSRTGVPGEDWPRYTAADRAVLVFDR
Mflv_3125|M.gilvum_PYR-GCK LLAAGLDSRSAKKVTDDVQKRWLGFAERAVPGGDWPQYTRDERAVLVLDR
MAB_3336c|M.abscessus_ATCC_199 ILTGSFTHRDASRVVDDVQQRWVAFARNGVPSGDWPPYRGPDWPVLVFDR
:*: * :* :: ** *.. ..*. .** * .* *:*
TH_0737|M.thermoresistible__bu NPRVEYDPDAHRRQAWQGFTLTRPDRN----
Mvan_3408|M.vanbaalenii_PYR-1 HPRLEYDPHAHRRQAWEGFSLA---------
MSMEG_3848|M.smegmatis_MC2_155 RPRVEYDPDADRRLAWEGFSLAQR-------
Mb2071c|M.bovis_AF2122/97 RCRIEFDPHQHRRIAWDGFSLAN--------
Rv2045c|M.tuberculosis_H37Rv RCRIEFDPHQHRRIAWDGFSLAN--------
MMAR_3020|M.marinum_M KSRVEIDPHQHRRLAWDGFSLAR--------
MUL_2261|M.ulcerans_Agy99 KSRVEIDPHRHRRLAWDGFSLAR--------
MAV_2466|M.avium_104 KSRVEFDPHPHRRMAWDGFSLAR--------
Mflv_3125|M.gilvum_PYR-GCK RRRVEFDPHSERRQAWEGFFLATR-------
MAB_3336c|M.abscessus_ATCC_199 ELRVEQNLGGDRRTVWDGFRLSIPSRIPRAS
. *:* : .** .*:** *: