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VTTTPEFAPFGFFTHYATVDADLLRTVESLGFDTAWLGGSPPADLPWIDPLLSATERIRIVTAIVNIWSA PAQQAAQSWQRIQQAHPGRFILGIGAGHPEIDSGVAYKPYSGLVEYLDVLDQAGVPQEGRALAALAEKSL KLAAQRSALAHPYLTPPSHTRWARELLGPDAVIVPEQKVVLTTDADEARTLGRQALDLYLGLTNYLTMLE RFAGSTDDLVKPGSDKLVDTLIAYGTPEQIAARLQEHRDAGATQVAIQVLGDPADRAKTLGVLARELGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3245 | - | - | 100% (279) | hypothetical protein MAB_3245 |
| M. abscessus ATCC 19977 | MAB_3778 | - | 6e-75 | 54.92% (244) | hypothetical protein MAB_3778 |
| M. abscessus ATCC 19977 | MAB_0995 | - | 2e-27 | 34.11% (258) | hypothetical protein MAB_0995 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3492 | - | 1e-75 | 52.73% (275) | hypothetical protein Mb3492 |
| M. gilvum PYR-GCK | Mflv_5005 | - | 7e-77 | 51.75% (286) | hypothetical protein Mflv_5005 |
| M. tuberculosis H37Rv | Rv3463 | - | 1e-75 | 52.73% (275) | hypothetical protein Rv3463 |
| M. leprae Br4923 | MLBr_00348 | - | 1e-06 | 29.09% (110) | putative coenzyme F420-dependent oxidoreductase |
| M. marinum M | MMAR_1083 | - | 3e-77 | 52.16% (278) | hypothetical protein MMAR_1083 |
| M. avium 104 | MAV_4404 | - | 2e-76 | 51.27% (275) | hypothetical protein MAV_4404 |
| M. smegmatis MC2 155 | MSMEG_4141 | - | 4e-76 | 52.35% (277) | hypothetical protein MSMEG_4141 |
| M. thermoresistible (build 8) | TH_0027 | - | 5e-73 | 50.96% (261) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0842 | - | 2e-75 | 51.62% (277) | hypothetical protein MUL_0842 |
| M. vanbaalenii PYR-1 | Mvan_1368 | - | 1e-76 | 51.99% (277) | hypothetical protein Mvan_1368 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4404|M.avium_104 -------------MTQAAGKPDLGRFGSFG-----RGVTPQQAKDIEALG
MUL_0842|M.ulcerans_Agy99 MPAPETDSDARSSASPAAGKPNLGRFGSFG-----RGVTPAQARDIEALG
Mb3492|M.bovis_AF2122/97 --------MTNCAAGKPSSGPNLGRFGSFG-----RGVTPQQATEIEALG
Rv3463|M.tuberculosis_H37Rv --------MTNCAAGKPSSGPNLGRFGSFG-----RGVTPQQATEIEALG
Mflv_5005|M.gilvum_PYR-GCK ---------------MSDVTPDLGRFGSFG-----RGVTPEQAQQIEALG
Mvan_1368|M.vanbaalenii_PYR-1 ---------------MTDTKPDLGRFGSFG-----RGVTPQQAKDIEALG
MSMEG_4141|M.smegmatis_MC2_155 ---MYRNILGAGPVDQTMTGLTLGTFGVFGRFQQWKQVTAAQLSDIEALG
MMAR_1083|M.marinum_M ------------MTNAVSLKPELGRFGVWLGSR---SITPELAGQIESLG
TH_0027|M.thermoresistible__bu ------------MTDAVSLKPDLGRFGVWTGG----PIPRELAAEIEKLG
MAB_3245|M.abscessus_ATCC_1997 ----------------MTTTPEFAPFGFFTHY---ATVDADLLRTVESLG
MLBr_00348|M.leprae_Br4923 ---------MVERANAMKLGLQLGYWAAQP-----PGNAAELVAAAEGAG
:. :. * *
MAV_4404|M.avium_104 YGAVWVGGSP-PAELAWVEPLLEATTTLQVATGIVNIWTAPAGPVAESFH
MUL_0842|M.ulcerans_Agy99 YGAVWVGGSP-PAELAWVEPILAATTTLQVATGIVNIWSAPAKPVAESFH
Mb3492|M.bovis_AF2122/97 YGAVWVGGSP-PAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFH
Rv3463|M.tuberculosis_H37Rv YGAVWVGGSP-PAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFH
Mflv_5005|M.gilvum_PYR-GCK YGAVWVGGSP-PAELDWVEPLLAATTTLQVATGIVNIWTADAGPVAESFH
Mvan_1368|M.vanbaalenii_PYR-1 YGAVWVGGSP-PAELDWVEPLLDATTTLQVATGIVNIWTAAAGPVAESFH
MSMEG_4141|M.smegmatis_MC2_155 YGAIWAGGSP-PAELDWIESILEPTKTLKVATGIVNIWSAAAGPVAESFH
MMAR_1083|M.marinum_M YGAAWIGASP-DADLAWVEPALEQTTSLQLATGIVNIWSAPADEVAASYQ
TH_0027|M.thermoresistible__bu YRALWVGGSP-AAELDFVEPILEATETLQVATGIVNIWTAPARTVAQSFH
MAB_3245|M.abscessus_ATCC_1997 FDTAWLGGSP-PADLPWIDPLLSATERIRIVTAIVNIWSAPAQQAAQSWQ
MLBr_00348|M.leprae_Br4923 FDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAAL
: : : * : : * : : *.:*:: : . * :
MAV_4404|M.avium_104 RIEAAYPGRFLLGIGVGHPEAHTEYR-----KPYDALADYLTRLDQYGVP
MUL_0842|M.ulcerans_Agy99 RIEAAYPGRFLLGIGVGHPEAITEYHST--GNAVDALIEYLNRLDDYGVP
Mb3492|M.bovis_AF2122/97 RIEAAYPGRFLLGIGVGHAEMISEYR-----KPYNALVEYLDRLDDYGVP
Rv3463|M.tuberculosis_H37Rv RIEAAYPGRFLLGIGVGHAEMISEYR-----KPYNALVEYLDRLDDYGVP
Mflv_5005|M.gilvum_PYR-GCK RIESAHPGRFLLGIGVGHPEAHQQYR-----RPIDALVEYLDKLDEYGVP
Mvan_1368|M.vanbaalenii_PYR-1 RIEAAHPGRFLLGIGVGHPEAHQEYV-----KPLDALTDYLDKLDEYGVP
MSMEG_4141|M.smegmatis_MC2_155 RIEKAHPGRFLLGIGAGHPELIAQYK-----KPYDALNEYLAELDEYGVP
MMAR_1083|M.marinum_M RIESAHPGRFLLGVGVGHPEHTQEYQ-----KPYDALVAYLDDLDKAMVP
TH_0027|M.thermoresistible__bu RIEKAYPGRFVLGLGVGHPEATEEYA-----KPYEAMVTYLDVLDEATVP
MAB_3245|M.abscessus_ATCC_1997 RIQQAHPGRFILGIGAGHPEIDSGVAY----KPYSGLVEYLDVLDQAGVP
MLBr_00348|M.leprae_Br4923 TLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAR
:: **.:**:*.. .: .. . *: : . .
MAV_4404|M.avium_104 AG------------------------------------RRVVAALGPRVL
MUL_0842|M.ulcerans_Agy99 AN------------------------------------RRVVAALGPRVL
Mb3492|M.bovis_AF2122/97 AN------------------------------------RRVVAALGPRVL
Rv3463|M.tuberculosis_H37Rv AN------------------------------------RRVVAALGPRVL
Mflv_5005|M.gilvum_PYR-GCK RG------------------------------------RRVVAALGPKVL
Mvan_1368|M.vanbaalenii_PYR-1 RG------------------------------------RRVVAALGPKVL
MSMEG_4141|M.smegmatis_MC2_155 RD------------------------------------QRVVAALGPQVL
MMAR_1083|M.marinum_M DS------------------------------------RRVLAALGPRML
TH_0027|M.thermoresistible__bu TS------------------------------------RRVLAALGPRML
MAB_3245|M.abscessus_ATCC_1997 QE------------------------------------GRALAALAEKSL
MLBr_00348|M.leprae_Br4923 EAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNV
:.* . : :
MAV_4404|M.avium_104 RLSAERSAGAHPYLTTPEHTARARELIGPSAFLAPEHKVVLTTDAE----
MUL_0842|M.ulcerans_Agy99 RLAARRSAGAHPYLTTPEHTGAARELIGPSAFLAPEHKVVLTTDAQ----
Mb3492|M.bovis_AF2122/97 GLSARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHKVVLTTDSA----
Rv3463|M.tuberculosis_H37Rv GLSARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHKVVLTTDSA----
Mflv_5005|M.gilvum_PYR-GCK KLSADRAAGAHPYLTTPEHTARARELIGPEAFLAPEHKVVLTTDERSREE
Mvan_1368|M.vanbaalenii_PYR-1 QLSATRAAGAHPYLTTPEHTARARELIGPEALLAPEHKVVLTTDAK----
MSMEG_4141|M.smegmatis_MC2_155 KLAARRSAGAHPYLTTPQHTAQARALVGPDALIAPAHKVVLNTDAA----
MMAR_1083|M.marinum_M RLAAQRSAGAHPYLTTPEHTGTARQLVGNTVFLAPEHKVVLTTDAA----
TH_0027|M.thermoresistible__bu QLAAQRSAGAHPYLTTPQHTGQARNRIGPSVFLAPEHKVVLDTDAA----
MAB_3245|M.abscessus_ATCC_1997 KLAAQRSALAHPYLTPPSHTRWARELLGPDAVIVPEQKVVLTTDAD----
MLBr_00348|M.leprae_Br4923 ALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICAS--
*:* . * : .* : . :. . :: :
MAV_4404|M.avium_104 ------HARAVGRKALDIYFNLANYRNNWKRLGFTDDEITRPGSDRLVDA
MUL_0842|M.ulcerans_Agy99 ------RARAVGRKALDIYLNLANYLNSWKRLGFSERDIARPGSDRLVDA
Mb3492|M.bovis_AF2122/97 ------RARTVGRQALDMYFNLANYRNNWKRLGFTDDEVSRPGSDRLVDA
Rv3463|M.tuberculosis_H37Rv ------RARTVGRQALDMYFNLANYRNNWKRLGFTDDEVSRPGSDRLVDA
Mflv_5005|M.gilvum_PYR-GCK HVTDPDRAREVGRKALEIYLDLANYLNSWKRLGFSDEDVAKPGSDRLVDA
Mvan_1368|M.vanbaalenii_PYR-1 ------QAREVGRKALDIYLNLANYLNNWKRLGFGDQDVAKPGSDRLVDA
MSMEG_4141|M.smegmatis_MC2_155 ------QARAIGREALAPYLKGTNYVNSWKRLGFTDSDVADPGSDALIDA
MMAR_1083|M.marinum_M ------QARAVGRKFIDFYLGLSNYVNNWLKLGFTEDDVRKPGSDRLIDA
TH_0027|M.thermoresistible__bu ------AAREIGRQTIGFYLRLRNYVNNWKQLGFTDDDIAEPGSDELIDA
MAB_3245|M.abscessus_ATCC_1997 ------EARTLGRQALDLYLGLTNYLTMLERFAGSTDDLVKPGSDKLVDT
MLBr_00348|M.leprae_Br4923 AQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDE
* . : :: * ::*
MAV_4404|M.avium_104 LVAYG---SVDRIAARLREHLDAG------ADHVPVQVLTKDENLVS--A
MUL_0842|M.ulcerans_Agy99 VVAYG---TPAAIAARLNEHLQAG------ADHVPVQVLTKSENLVP--A
Mb3492|M.bovis_AF2122/97 VVAYG---TPDAIAARLNEHLLAG------ADHVPIQVLTEDDNLVS--A
Rv3463|M.tuberculosis_H37Rv VVAYG---TPDAIAARLNEHLLAG------ADHVPIQVLTEDDNLVS--A
Mflv_5005|M.gilvum_PYR-GCK VVAYG---TAEQIAARLREHLDAG------ADHVPVQVLTGSDKLVP--A
Mvan_1368|M.vanbaalenii_PYR-1 VVAYG---TVDAIAARLTEHLDAG------ADHVPVQVLTGSEKLVP--A
MSMEG_4141|M.smegmatis_MC2_155 LVAYG---KTDAIAARLNEHLAAG------ATHVSVQVLTEPEELIP--S
MMAR_1083|M.marinum_M LVAYG---TPDQIARRLGEHLEAG------ADHVAIQVLRPSREDKPMAA
TH_0027|M.thermoresistible__bu MVAHG---TAEQVADALREHLDRG------ADHVAIQVLGGRERLLPTLX
MAB_3245|M.abscessus_ATCC_1997 LIAYG---TPEQIAARLQEHRDAG------ATQVAIQVLGDPADRAK--T
MLBr_00348|M.leprae_Br4923 VTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMM
: * * : :. . . * *:
MAV_4404|M.avium_104 LAELAGP-----LGLKPS----------------------
MUL_0842|M.ulcerans_Agy99 LAELAGP-----LGLAGA----------------------
Mb3492|M.bovis_AF2122/97 LTELAKP-----LRLT------------------------
Rv3463|M.tuberculosis_H37Rv LTELAKP-----LRLT------------------------
Mflv_5005|M.gilvum_PYR-GCK LAELAGP-----LGLESTEEQR------------------
Mvan_1368|M.vanbaalenii_PYR-1 LAELAGP-----LGLQRKG---------------------
MSMEG_4141|M.smegmatis_MC2_155 LTALAGP-----LGLT------------------------
MMAR_1083|M.marinum_M LTELSG-----ALGLTR-----------------------
TH_0027|M.thermoresistible__bu XSPRCGPNWGRCTSWSRARVWWTSPRSPRSAGRPGSGSSM
MAB_3245|M.abscessus_ATCC_1997 LGVLARE-----LGL-------------------------
MLBr_00348|M.leprae_Br4923 VSASSVEQVRDLAGLF------------------------
.