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ATFDLLVRGGLVFDGTGAPGRAVDVGIRGGNVVAMAPDLPAADADQVIDAGGKWVIPGMVDVHTHYDAEV LVSPGLGESVRHGVTSVIYGNCSMSAVYADPEDVADLFARVEALPWDAVHSALKEHKDWDGPRGYRKVIE SLPLGANVATLIGHSDIRAAVMGLARATDYDERPTAGELARMRAMVTDALDAGFVGLSTDRLRFSKLEGT RFAGRQLPSTYATWREYGALYDVVRRRGAVVQSNLDVEKRPETIMHFLLSGARPWRRSLKTTLLAAFDLK SNRSVIKLLKAATGGLNPLLRSQVNFQLLAVPFHLYSDGMDLVIFEEFASGTAALDIRDQLQRVDLIKDE GYRRKFRKEMAQKYGVVAWNRDMYDTEIVGCPDESVVGKSFGQVADARGVQPVDAFLDLVSEYPGKVRWH TTIANDRTDVLNEAVKYRHFQLGNNDSGAHLRNMSFYNAGLRLLKRVKEAREAGTPFMSLEAAVHRLTGE LGEWYGLDAGRLRIGDTADIAVIDPAGLDDSLDEYHEQYMEEFGVSRQVCRNDNAIAATIVGGQQVYSYG TFVEGFGSTVKAGRFLAAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2965c | - | - | 100% (580) | hypothetical protein MAB_2965c |
| M. abscessus ATCC 19977 | MAB_0680c | - | e-162 | 51.11% (585) | hypothetical protein MAB_0680c |
| M. abscessus ATCC 19977 | MAB_2605c | - | e-161 | 51.12% (581) | hypothetical protein MAB_2605c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2937c | - | 1e-163 | 51.45% (587) | D-amino acid aminohydrolase |
| M. gilvum PYR-GCK | Mflv_3313 | - | 1e-87 | 51.90% (316) | hypothetical protein Mflv_3313 |
| M. tuberculosis H37Rv | Rv2913c | - | 1e-163 | 51.45% (587) | D-amino acid aminohydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1795 | - | 1e-160 | 51.62% (585) | D-amino acid aminohydrolase |
| M. avium 104 | MAV_3768 | - | 1e-169 | 52.23% (584) | N-acyl-D-glutamate amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_6141 | - | 1e-160 | 50.69% (582) | N-acyl-D-glutamate amidohydrolase |
| M. thermoresistible (build 8) | TH_2847 | - | 9e-34 | 26.46% (601) | PUTATIVE Amidohydrolase 3 |
| M. ulcerans Agy99 | MUL_2043 | - | 1e-160 | 51.45% (585) | D-amino acid aminohydrolase |
| M. vanbaalenii PYR-1 | Mvan_3035 | - | 1e-160 | 51.12% (581) | hypothetical protein Mvan_3035 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2937c|M.bovis_AF2122/97 MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAA
Rv2913c|M.tuberculosis_H37Rv MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAA
MMAR_1795|M.marinum_M -------------MTYDVIIRDGLWFDGTGSAPQTRTLGIRDGVVATVSA
MUL_2043|M.ulcerans_Agy99 -------------MTYDVIIRDGLWFDGTGSAPQTRTLGIRDGMVATVSA
MAV_3768|M.avium_104 -------------MPYDVIIRDGLWFDGTGGAALTRTLGIRDGVLVDVAE
MSMEG_6141|M.smegmatis_MC2_155 -------------MSYDVIVRNGLWFDGTGRPPQVRTLGIRDGVVATVSA
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 -----MRALFDEPVTFDTIIRNGRWFDGTGAPSAVRNLGIRDGHVVSISE
MAB_2965c|M.abscessus_ATCC_199 ------------MATFDLLVRGGLVFDGTGAPGRAVDVGIRGGNVVAMAP
TH_2847|M.thermoresistible__bu -------------MTFDLVIRNGTIVDGLGGEPFTGDVAVADGVIVAVGT
Mb2937c|M.bovis_AF2122/97 GALDETGCPEVVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRHGVTT
Rv2913c|M.tuberculosis_H37Rv GALDETGCPEVVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRHGVTT
MMAR_1795|M.marinum_M GPLDETGCAQVIDAAGKWVMPGFIDVHTHYDAEVLLDPGLRESVRHGVTT
MUL_2043|M.ulcerans_Agy99 GPLDETGCAQVIDAAGKWVMPGFIDVHTHYDAEVLLDPGLRESVRHGVTT
MAV_3768|M.avium_104 S-LDEAGCPEVIDAAGKWVLPGFIDVHTHYDAEVLLDPGLRESVRHGVTT
MSMEG_6141|M.smegmatis_MC2_155 KPLDETGCPEVIDAGGKWVVPGFIDVHTHYDAEVLLDPGLRESVRHGVTT
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 DELDATGCPQVIDAVGKWVLPGMLDIHTHYDIEVLGGPSLAESLRHGVTT
MAB_2965c|M.abscessus_ATCC_199 D-LPAADADQVIDAGGKWVIPGMVDVHTHYDAEVLVSPGLGESVRHGVTS
TH_2847|M.thermoresistible__bu ADGSGR---REIDATGLLVTPGFIDLHTHYDGQSIWSDRLNPSSAHGVTT
Mb2937c|M.bovis_AF2122/97 VLLGNCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQ---TWSTPA
Rv2913c|M.tuberculosis_H37Rv VLLGNCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQ---TWSTPA
MMAR_1795|M.marinum_M VLLGNCSLSTVYAGAEDAADLFSRVEAVPRQFVLGALSAAKSERAWSNAA
MUL_2043|M.ulcerans_Agy99 VLLGNCSLSTVYAGAEDAADLFSRVEAVPRQFVLGALSAAKSERAWSNAA
MAV_3768|M.avium_104 VLLGNCSLSTVYADSQDAADLFSRVEAVPREYVYGALSSNR---TWSTAA
MSMEG_6141|M.smegmatis_MC2_155 VLLGMCSLSTVYSDAEDAADLFSRVEAVPRQFVLGALESRK---TWSNPA
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 VLLGSCSLSTVYVDGVDAGDIFGRVEAIPREHVIAAVDRHK---TWTTGE
MAB_2965c|M.abscessus_ATCC_199 VIYGNCSMSAVYADPEDVADLFARVEALPWDAVHSALKEHK---DWDGPR
TH_2847|M.thermoresistible__bu ALMGNCGVGFAPCRPEDHDVLVDVMAGV--EDIPGVVMAEGLPWTWETFP
Mb2937c|M.bovis_AF2122/97 EYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDRATDDTVRPTEAELAKMA
Rv2913c|M.tuberculosis_H37Rv EYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDRATDDTVRPTEAELAKMA
MMAR_1795|M.marinum_M EYITAIDSLPLGPNVSSLLGHSDLRATVLGLERATDASVRPSEAELGRMA
MUL_2043|M.ulcerans_Agy99 EYITAIDSLPLGPNVSSLLGHSDLRATVLGLERATDASVRPSEAELGRMA
MAV_3768|M.avium_104 DYVKAVDALPLGPNVGSLLGHSDLRAAVLGLDRATDATVRPTDAELEKMA
MSMEG_6141|M.smegmatis_MC2_155 EYVAAIDALPLGPNIASLLGHSDLRASVLGLDRATTRGVVPTDDELETMA
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 EYIAALESRPLGPNVAAFIGHSDMRTATMGLDRATRKDERPTGSEQAQME
MAB_2965c|M.abscessus_ATCC_199 GYRKVIESLPLGANVATLIGHSDIRAAVMGLARATDYDERPTAGELARMR
TH_2847|M.thermoresistible__bu QYLDAVASRPRDIDVAAYLPHSPLRVYVMGRRGVDREPATP--DDLERMR
Mb2937c|M.bovis_AF2122/97 KLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRERRKLIS-
Rv2913c|M.tuberculosis_H37Rv KLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRERRKLIS-
MMAR_1795|M.marinum_M TLLDEALDAGMLGMSGMDSAIDKLDGERFRSRALPSTFATWRERRRLIK-
MUL_2043|M.ulcerans_Agy99 TLLDEALDAGMLGMSGMDSAIDKLDGERFRSRALPSTFATWRERRRLIK-
MAV_3768|M.avium_104 ALLDEALDAGLLGMSGMDAAIDKLDGERFRSRALPSTFATWRERRKLIE-
MSMEG_6141|M.smegmatis_MC2_155 DRLDAALDAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRERRRLIK-
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 RMLTEALRAGFVGMSSQQLLFDKLDGEVCRSRTLPSTYAKPRELRRLKS-
MAB_2965c|M.abscessus_ATCC_199 AMVTDALDAGFVGLSTDRLRFSKLEGTRFAGRQLPSTYATWREYGALYD-
TH_2847|M.thermoresistible__bu ALAAEAVAAGALGFASSRFALHKTES----GSPIPTYDAAQEEIAAIARG
Mb2937c|M.bovis_AF2122/97 VLRHRGRILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSADAK-
Rv2913c|M.tuberculosis_H37Rv VLRHRGRILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSADAK-
MMAR_1795|M.marinum_M VLRKRGRILQSAPNVDKPASALLFFLASSRILNRRKGVRMSLLVSADSK-
MUL_2043|M.ulcerans_Agy99 VLRKRGRILQSAPNVDKPASALLFFLASSRILNRRKGVRMSLLVSADSK-
MAV_3768|M.avium_104 VLRRRGRILQSAPDLDNPALALMFFLTSSRIFGRGRGVRMSMLVSADAK-
MSMEG_6141|M.smegmatis_MC2_155 VLRKRGRILQSAPNVAKAQEALNFFLESSSLFGRRRGVRMSLLVSADAK-
Mflv_3313|M.gilvum_PYR-GCK ------------------------MFQSLGIVRN--PLKTSLLSAADVK-
Mvan_3035|M.vanbaalenii_PYR-1 LLRRSGRVLQSGPDITNPLNVASQVFQSLGLVRN--PLKTSLLSAADVK-
MAB_2965c|M.abscessus_ATCC_199 VVRRRGAVVQSNLDVEKRPETIMHFLLS-GARPWRRSLKTTLLAAFDLK-
TH_2847|M.thermoresistible__bu VADAGGGLLQFVPDIPAGGYESVLRQVFEVGAETGLPVTFSLLTGNAGEP
: ::* . :
Mb2937c|M.bovis_AF2122/97 ---SMPLAVHVFGLGTRVLNKLLGSQVRFQHLPVPFELYSDGIDLPVFEE
Rv2913c|M.tuberculosis_H37Rv ---SMPLAVHVFGLGTRVLNKLLGSQVRFQHLPVPFELYSDGIDLPVFEE
MMAR_1795|M.marinum_M ---SMPMAVHTFGLGARLLNKLLAASVRFQHLPVPFELYSDGIDLPVFEE
MUL_2043|M.ulcerans_Agy99 ---SMPMAVRTFGLGARLLNKLLAASVRFQHLPVPFELYSDGIDLPVFEE
MAV_3768|M.avium_104 ---SMPLAVHTFGLGTRILNKLLRSSVRFQHLPVPFELYSDGIDLPVFEE
MSMEG_6141|M.smegmatis_MC2_155 ---SSPGAARVIGMGTRLLNKTLDAKVRFQHLPVPFELYSDGIDLPVFEE
Mflv_3313|M.gilvum_PYR-GCK ---SNPVAVKLLGPLARLANR-LGGNFRWQHLPVPFEVYADGIDLVIFEE
Mvan_3035|M.vanbaalenii_PYR-1 ---SNPVAVKLLGPLARLANR-LGGNFRWQHLPVPFEVYADGIDLVIFEE
MAB_2965c|M.abscessus_ATCC_199 ---SNRSVIKLLKAATGGLNPLLRSQVNFQLLAVPFHLYSDGMDLVIFEE
TH_2847|M.thermoresistible__bu TWPQALNLVEKFNAAAGGAAPAVTAQVFPRPIGMVMSLELSANPFVMYPS
. . : : : ... : : : : : .. : :: .
Mb2937c|M.bovis_AF2122/97 FGAGTAALHLRDQLQRNELLADRSYRRSFRREFDRIKLGPSLWHRDFHDA
Rv2913c|M.tuberculosis_H37Rv FGAGTAALHLRDQLQRNELLADRSYRRSFRREFDRIKLGPSLWHRDFHDA
MMAR_1795|M.marinum_M FGAGTAALHLREQVQRNQLLADESYRREFRREFDRTKLGPSLWHKDFHDA
MUL_2043|M.ulcerans_Agy99 FGAGTAALHLREQVQRNQLLADESYRSEFRREFDRTKLGPSLWHKDFHDA
MAV_3768|M.avium_104 FGAGTAALHLRDQLQRNELLADTDYRRRFRREFDRVKLGPSLWHRDFHDA
MSMEG_6141|M.smegmatis_MC2_155 FGAGTAALHLRDQLERNKLLADPEYRRRFRRSFDRRKLGPTLWHRDFHDA
Mflv_3313|M.gilvum_PYR-GCK FGSGAAALHLKDEVERNALLRDENYRREFRKDYD-AKFGMRVWHRDFFDA
Mvan_3035|M.vanbaalenii_PYR-1 FGSGAAALHLADEVDRNALLRDESYRRRFRKDYD-ARFGMRVWHRDFFDA
MAB_2965c|M.abscessus_ATCC_199 FASGTAALDIRDQLQRVDLIKDEGYRRKFRKEMA-QKYGVVAWNRDMYDT
TH_2847|M.thermoresistible__bu Y-REIAGLPLPQQVAEMRKPEVRERILNDKPAGDGHPLFFMTQAWDWIYP
: *.* : ::: . : * .
Mb2937c|M.bovis_AF2122/97 VIVECPDKSLIGKSFGAIADERG-LHPLDAFLDVLVDNGERNVRWTTI--
Rv2913c|M.tuberculosis_H37Rv VIVECPDKSLIGKSFGAIADERG-LHPLDAFLDVLVDNGERNVRWTTI--
MMAR_1795|M.marinum_M VIVECPDESLIGKSFGAIADERG-LHPLDAFLDVLVENGERNVRWTTV--
MUL_2043|M.ulcerans_Agy99 VIVECPDESLIGKSFGAIADERG-LHPLDAFLDVLVENGERNVRWTTV--
MAV_3768|M.avium_104 VIVECPDKSLIGKSFGAIADERG-LHPLDAFLDVLVENGERNVRWTTT--
MSMEG_6141|M.smegmatis_MC2_155 TIVECPDESLIGKTFGRIADERG-IHPLDAFLDVLVDNGEKNVRWTTI--
Mflv_3313|M.gilvum_PYR-GCK EIVACPDPAVIGKSFGEVGRDRGGLHPVDAFLDLVLEHG-NELRWRTT--
Mvan_3035|M.vanbaalenii_PYR-1 QIVACPDVSVIGKSFGEVGRERGGLHPVDAFLDLVLEHG-KGLRWRTT--
MAB_2965c|M.abscessus_ATCC_199 EIVGCPDESVVGKSFGQVADARG-VQPVDAFLDLVSEYP-GKVRWHTT--
TH_2847|M.thermoresistible__bu LGEQPDYEPDASTSIAARARARG-VSPLEEAYDRLLDDDGHAMLLIAMGN
. ..::. . ** : *:: * : : : :
Mb2937c|M.bovis_AF2122/97 VANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLRLLKRARDADR
Rv2913c|M.tuberculosis_H37Rv VANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLRLLKRARDADR
MMAR_1795|M.marinum_M VANHRPKQLNKLAAEPGVHMGFSDAGAHLRNMAFYNFPLRLLKRTWDAER
MUL_2043|M.ulcerans_Agy99 VANHRPKQLNKLAAEPGVHMGFSDAGAHLRNMAFYNFPLRLLKRTWDAER
MAV_3768|M.avium_104 VANHRPKQLDKLAADPSIHMGFSDAGAHLRNMAFYNFALRMLKRTRDAQA
MSMEG_6141|M.smegmatis_MC2_155 VANHRPKVLDQLANDPAVHMGFSDAGAHLRNMAFYNYPLRLLKRVRDAQL
Mflv_3313|M.gilvum_PYR-GCK ISNHRPEVLRKLAADSGIQMGFSDAGAHLRNMAFYNMGLRLLRHVQDAVR
Mvan_3035|M.vanbaalenii_PYR-1 ISNHRPEVLRKLAADPGIQMGFSDAGAHLRNMAFYNMGLRLLRHVQDAAR
MAB_2965c|M.abscessus_ATCC_199 IANDRTDVLNEAVKYRHFQLGNNDSGAHLRNMSFYNAGLRLLKRVKEARE
TH_2847|M.thermoresistible__bu YENNSLDTVGQWMRRDDVVLGLGDGGAHYGMICDASYPTFLLAHWARDRA
*. . : : . :* .*.*** :. . :* :
Mb2937c|M.bovis_AF2122/97 AGQPFLSIERAVYRLTGELAEWFGIG-AGTLRQGDRADFAVIDPTHLDES
Rv2913c|M.tuberculosis_H37Rv AGQPFLSIERAVYRLTGELAEWFGIG-AGTLRQGDRADFAVIDPTHLDES
MMAR_1795|M.marinum_M AGKPFLSLQQAVYRLTGELAEWFGVD-AGTLREGDRADFVVIDPAHLDES
MUL_2043|M.ulcerans_Agy99 AGKPFLSLQQAVYRLTGELAEWFGVD-AGTLREGDRADFVVIDPAHLDES
MAV_3768|M.avium_104 AGAPFLTIERAVHRLTGELADWFGID-AGTLRPGDRADFVVIDPAGLDES
MSMEG_6141|M.smegmatis_MC2_155 SGRPFLTTERAVYRLTAEVADWFGVD-AGTLREGDRADFVVIDPNCLNSD
Mflv_3313|M.gilvum_PYR-GCK AGRPFMTIEAAVHRLTGELADWYRID-AGHLRLGDRADIVILDPERLDAS
Mvan_3035|M.vanbaalenii_PYR-1 SGRPFMTVEQAVHRLTGELADWYRID-AGHLRLGDRADLVIVDPERLDDT
MAB_2965c|M.abscessus_ATCC_199 AGTPFMSLEAAVHRLTGELGEWYGLD-AGRLRIGDTADIAVIDPAGLDDS
TH_2847|M.thermoresistible__bu SGR--LTVAEAVRALTSVPARVAGFGDRGRIAVGYKADLNVID----HAA
:* :: ** **. . .. * : * **: ::* .
Mb2937c|M.bovis_AF2122/97 VDGYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFRGGQFGGQFRDGY
Rv2913c|M.tuberculosis_H37Rv VDGYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFRGGQFGGQFRDGY
MMAR_1795|M.marinum_M VDGYHEAQVPFYGGLSRMVNRNDATVIATGVAGAVVFGS----GQFRDGY
MUL_2043|M.ulcerans_Agy99 VDGYHEAQVPFYGGLSRMVNRNDATVIATGVAGAVVFGT----GQFRDGY
MAV_3768|M.avium_104 VDAYHEEAVPFYGGLRRMINRNDDAVVATGVGGVVVFGGSHRKGEFRDGY
MSMEG_6141|M.smegmatis_MC2_155 VDAYHEETVPFYGGLSRMVNRNDDAVVATAVNGTVVFGK----GEFRDGY
Mflv_3313|M.gilvum_PYR-GCK LDAYAEETVDQYGGLSRMVNRNDDTVSAVFVGGRAVFNG----GVPTPLV
Mvan_3035|M.vanbaalenii_PYR-1 LDRYAEEPVEQYGGLSRMVNRNDDTVAAVFVGGRAVFLD----GRPTPLV
MAB_2965c|M.abscessus_ATCC_199 LDEYHEQYMEEFG-VSRQVCRNDNAIAATIVGGQQVYSY----GTFVEGF
TH_2847|M.thermoresistible__bu LRLHRPVILHDLPSGGRRLDQRADGYVATVVSGHIIAEN---------GV
: : : * : :. *. * * :
Mb2937c|M.bovis_AF2122/97 GQNVKSGRYLRAGELGAALSRSA-------
Rv2913c|M.tuberculosis_H37Rv GQNVKSGRYLRAGELGAALSRSA-------
MMAR_1795|M.marinum_M GQTVRSGRYLRAGQRYTAASVSA-------
MUL_2043|M.ulcerans_Agy99 GQTVRSGRYLRAGQRYTAASVSA-------
MAV_3768|M.avium_104 GHTVKSGRYLRAGQRVRAKGGAPRVTA---
MSMEG_6141|M.smegmatis_MC2_155 GDTVKSGRYLRAGADSRLKTAV--------
Mflv_3313|M.gilvum_PYR-GCK G-EHRTGRFLRAAHRVPALPATEGVLTHAG
Mvan_3035|M.vanbaalenii_PYR-1 G-AERTGRFLRAAHKAPALLAQNGALAHAG
MAB_2965c|M.abscessus_ATCC_199 GSTVKAGRFLAAS-----------------
TH_2847|M.thermoresistible__bu PTDARPGTLVRGRQPAPKVAG---------
:.* : .