For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VFQSLGIVRNPLKTSLLSAADVKSNPVAVKLLGPLARLANRLGGNFRWQHLPVPFEVYADGIDLVIFEEF GSGAAALHLKDEVERNALLRDENYRREFRKDYDAKFGMRVWHRDFFDAEIVACPDPAVIGKSFGEVGRDR GGLHPVDAFLDLVLEHGNELRWRTTISNHRPEVLRKLAADSGIQMGFSDAGAHLRNMAFYNMGLRLLRHV QDAVRAGRPFMTIEAAVHRLTGELADWYRIDAGHLRLGDRADIVILDPERLDASLDAYAEETVDQYGGLS RMVNRNDDTVSAVFVGGRAVFNGGVPTPLVGEHRTGRFLRAAHRVPALPATEGVLTHAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3313 | - | - | 100% (339) | hypothetical protein Mflv_3313 |
| M. gilvum PYR-GCK | Mflv_0136 | - | 5e-07 | 24.09% (303) | amidohydrolase 3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2937c | - | 1e-101 | 56.50% (331) | D-amino acid aminohydrolase |
| M. tuberculosis H37Rv | Rv2913c | - | 1e-101 | 56.50% (331) | D-amino acid aminohydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2605c | - | 1e-151 | 74.33% (335) | hypothetical protein MAB_2605c |
| M. marinum M | MMAR_1795 | - | 1e-103 | 58.20% (323) | D-amino acid aminohydrolase |
| M. avium 104 | MAV_2959 | - | 1e-137 | 71.34% (328) | N-acyl-D-glutamate amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_1997 | - | 1e-134 | 72.45% (323) | N-acyl-D-glutamate amidohydrolase |
| M. thermoresistible (build 8) | TH_3974 | - | 5e-06 | 26.88% (186) | PUTATIVE Amidohydrolase 3 |
| M. ulcerans Agy99 | MUL_2043 | - | 1e-102 | 57.89% (323) | D-amino acid aminohydrolase |
| M. vanbaalenii PYR-1 | Mvan_3035 | - | 1e-177 | 89.09% (339) | hypothetical protein Mvan_3035 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2937c|M.bovis_AF2122/97 MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVA-
Rv2913c|M.tuberculosis_H37Rv MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVA-
MMAR_1795|M.marinum_M -------------MTYDVIIRDGLWFDGTGSAPQTRTLGIRDGVVATVS-
MUL_2043|M.ulcerans_Agy99 -------------MTYDVIIRDGLWFDGTGSAPQTRTLGIRDGMVATVS-
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 -----MRALFDEPVTFDTIIRNGRWFDGTGAPSAVRNLGIRDGHVVSIS-
MAB_2605c|M.abscessus_ATCC_199 -------MVPCSDAQFDTVIRNGRWFDGTGAPSAIRNIGIKDGHVAAVS-
MSMEG_1997|M.smegmatis_MC2_155 -------------MTFDKVILGGRLFDGTGGPSALRNIGIRDGRVAAIT-
MAV_2959|M.avium_104 -------------MGYDTVITNGRWFDGTGGPSAMRDIGVRDGRVVTIA-
TH_3974|M.thermoresistible__bu -------------MVFDLKITGGTVVDGTGADRFLGDIGIAGGTIVEVRR
Mb2937c|M.bovis_AF2122/97 ---AGALDETGCPEVVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRH
Rv2913c|M.tuberculosis_H37Rv ---AGALDETGCPEVVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRH
MMAR_1795|M.marinum_M ---AGPLDETGCAQVIDAAGKWVMPGFIDVHTHYDAEVLLDPGLRESVRH
MUL_2043|M.ulcerans_Agy99 ---AGPLDETGCAQVIDAAGKWVMPGFIDVHTHYDAEVLLDPGLRESVRH
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 ---EDELDATGCPQVIDAVGKWVLPGMLDIHTHYDIEVLGGPSLAESLRH
MAB_2605c|M.abscessus_ATCC_199 ---ADDLDETHCPNIIDASGKWVLPGLVDIHTHYDIEVLAAPALSESVRH
MSMEG_1997|M.smegmatis_MC2_155 ---ADAVEGT---ETVDASGCWVMPGMIDIHTHYDAEVLAAPGLTESLRH
MAV_2959|M.avium_104 ---AGPLDTAG-ATVIDASGQWVIPGIIDIHTHYDVEILCEPELSESLRH
TH_3974|M.thermoresistible__bu RGPGDPPLEGAAAETLDATGTIVAPGFVDIHTHYDGQVSWDDLLEPSSGH
Mb2937c|M.bovis_AF2122/97 GVTTVLLGNCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQ---TW
Rv2913c|M.tuberculosis_H37Rv GVTTVLLGNCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQ---TW
MMAR_1795|M.marinum_M GVTTVLLGNCSLSTVYAGAEDAADLFSRVEAVPRQFVLGALSAAKSERAW
MUL_2043|M.ulcerans_Agy99 GVTTVLLGNCSLSTVYAGAEDAADLFSRVEAVPRQFVLGALSAAKSERAW
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 GVTTVLLGSCSLSTVYVDGVDAGDIFGRVEAIPREHVIAAVDRHK---TW
MAB_2605c|M.abscessus_ATCC_199 GVTTVLLGSCSLSVVHVDGVDAGDIFGRVEAIPRDHVIQVVDRYK---TW
MSMEG_1997|M.smegmatis_MC2_155 GVTSIVMGSCSLSTVHVNGSEAADLFGRVEAIPHEHVVRIVGEHK---TW
MAV_2959|M.avium_104 GVTTVLVGSCSLSTVYLDNVDAGDIFGRVEAIPRRYVIEHLKAAR---SW
TH_3974|M.thermoresistible__bu GVTTVVMGNCGVGFAPVRPGREEWLIELMEGVEDIPGAALSEGIS--WGW
Mb2937c|M.bovis_AF2122/97 STPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDRATDDTVRPTEAEL
Rv2913c|M.tuberculosis_H37Rv STPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDRATDDTVRPTEAEL
MMAR_1795|M.marinum_M SNAAEYITAIDSLPLGPNVSSLLGHSDLRATVLGLERATDASVRPSEAEL
MUL_2043|M.ulcerans_Agy99 SNAAEYITAIDSLPLGPNVSSLLGHSDLRATVLGLERATDASVRPSEAEL
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 TTGEEYIAALESRPLGPNVAAFIGHSDMRTATMGLDRATRKDERPTGSEQ
MAB_2605c|M.abscessus_ATCC_199 TNAGQYVAALESLPLGPNVAAFLGHSDIRAAAMGLDRATRKDERPTAAEQ
MSMEG_1997|M.smegmatis_MC2_155 NNAEEYIEALEARPLGPNVTAFIGHSDIRVAVMGLDRATRKDVRPTKAEQ
MAV_2959|M.avium_104 TNPKEYVAELERRNLGPNVAAFIGHSDMRAATMGLDRATRKDVRPSAAEL
TH_3974|M.thermoresistible__bu ESYADYLDVIGGRKLAIDVGSQIAHGTVRAYAMGERGARNEPATP--DDI
Mb2937c|M.bovis_AF2122/97 AKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRERRK
Rv2913c|M.tuberculosis_H37Rv AKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRERRK
MMAR_1795|M.marinum_M GRMATLLDEALDAGMLGMSGMDSAIDKLDGERFRSRALPSTFATWRERRR
MUL_2043|M.ulcerans_Agy99 GRMATLLDEALDAGMLGMSGMDSAIDKLDGERFRSRALPSTFATWRERRR
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 AQMERMLTEALRAGFVGMSSQQLLFDKLDGEVCRSRTLPSTYAKPRELRR
MAB_2605c|M.abscessus_ATCC_199 AQMDRWLTEALDAGFVGMSSQQLLFDKLDGDVCRSRTLPSTYAKPRELRR
MSMEG_1997|M.smegmatis_MC2_155 ARMEQMLTDALDTGFIGLSSQQLLFDKLDGDVCRSRTLPSTYARAKELRR
MAV_2959|M.avium_104 ARMETMLNEALDEGFVGMSSQQLLFDKLDGEVCRSRTLPSTYAAPRELRR
TH_3974|M.thermoresistible__bu AAMSRIVREAAEAGALGFSSS----RTLAHRAIDGEPVPGTFAAEDELFA
Mb2937c|M.bovis_AF2122/97 LISVLRHRG-RILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSA
Rv2913c|M.tuberculosis_H37Rv LISVLRHRG-RILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSA
MMAR_1795|M.marinum_M LIKVLRKRG-RILQSAPNVDKPASALLFFLASSRILNRRKGVRMSLLVSA
MUL_2043|M.ulcerans_Agy99 LIKVLRKRG-RILQSAPNVDKPASALLFFLASSRILNRRKGVRMSLLVSA
Mflv_3313|M.gilvum_PYR-GCK ----------------------------MFQSLGIV--RNPLKTSLLSAA
Mvan_3035|M.vanbaalenii_PYR-1 LKSLLRRSG-RVLQSGPDITNPLNVASQVFQSLGLV--RNPLKTSLLSAA
MAB_2605c|M.abscessus_ATCC_199 LKAQLRQRN-RVLQSGPDIQNPLNVLSQAVQSLGIL--RRPLSTSLLSAA
MSMEG_1997|M.smegmatis_MC2_155 LKSILRRRD-RTLQSGPDISHPHNIVSQAFQSVGIG--RPRLKTSLLAAA
MAV_2959|M.avium_104 LNAILRRRD-KILQSGPDITNPLSVLSQLMTSLGIG--RPRLKTSLLSAA
TH_3974|M.thermoresistible__bu LGRALADGGGAVFELAPQGAAGEDIVAPGKELEWMRRLGAEIDCALSFAL
: : :: :
Mb2937c|M.bovis_AF2122/97 DAKSMPLAVHVFGLGTRVLNKLLGSQVRFQHLPVPFELYSDGIDLPVFEE
Rv2913c|M.tuberculosis_H37Rv DAKSMPLAVHVFGLGTRVLNKLLGSQVRFQHLPVPFELYSDGIDLPVFEE
MMAR_1795|M.marinum_M DSKSMPMAVHTFGLGARLLNKLLAASVRFQHLPVPFELYSDGIDLPVFEE
MUL_2043|M.ulcerans_Agy99 DSKSMPMAVRTFGLGARLLNKLLAASVRFQHLPVPFELYSDGIDLPVFEE
Mflv_3313|M.gilvum_PYR-GCK DVKSNPVAVKLLGPLARLANRLGG-NFRWQHLPVPFEVYADGIDLVIFEE
Mvan_3035|M.vanbaalenii_PYR-1 DVKSNPVAVKLLGPLARLANRLGG-NFRWQHLPVPFEVYADGIDLVIFEE
MAB_2605c|M.abscessus_ATCC_199 DIKANPYAIRAMGPVASLVNKLGG-NFRWQHLPVPFEVYADGIDLVIFEE
MSMEG_1997|M.smegmatis_MC2_155 DMKSTPGGMWFTVALAAIANRLGG-DFRFQHLPVPFEVYADGIDLVIFEE
MAV_2959|M.avium_104 DIKAIPFVIHVMDRLARVVNALGG-DFRWQHLPVPFEVYADGISLVVFEE
TH_3974|M.thermoresistible__bu IQVDADPNLWREQLEISAAAHEAGSRLYPQVAARPFGMLLG---FPGHHA
: . . * . ** : . : ..
Mb2937c|M.bovis_AF2122/97 FGAGTAALHLRDQLQRNELLA--DRSYRRSFRREFDRIKLGPSLWHRDFH
Rv2913c|M.tuberculosis_H37Rv FGAGTAALHLRDQLQRNELLA--DRSYRRSFRREFDRIKLGPSLWHRDFH
MMAR_1795|M.marinum_M FGAGTAALHLREQVQRNQLLA--DESYRREFRREFDRTKLGPSLWHKDFH
MUL_2043|M.ulcerans_Agy99 FGAGTAALHLREQVQRNQLLA--DESYRSEFRREFDRTKLGPSLWHKDFH
Mflv_3313|M.gilvum_PYR-GCK FGSGAAALHLKDEVERNALLR--DENYRREFRKDYD-AKFGMRVWHRDFF
Mvan_3035|M.vanbaalenii_PYR-1 FGSGAAALHLADEVDRNALLR--DESYRRRFRKDYD-ARFGMRVWHRDFF
MAB_2605c|M.abscessus_ATCC_199 FGAGAAALHLRDEVERNELLR--DEKYRRRFRKEYE-SKFGVRVWHRDFF
MSMEG_1997|M.smegmatis_MC2_155 FGSGAAALHLKTEMERNKLLA--DEGYRRRFRKDYD-NKFGPRAWHRDFF
MAV_2959|M.avium_104 FGSGAAALHLQTEIERNRLMR--DEGYRRRFRKDYD-SRFGPRVWHRDFF
TH_3974|M.thermoresistible__bu FTHRPTYRRLAAECDREELAARLAEPAVRAAILAEDDLPPDPDVLFDGMF
* .: :* : :*: * . : . . .:.
Mb2937c|M.bovis_AF2122/97 DAVIVECPDKSLIG----------KSFGAIADERG-LHPLDAFLDVLVDN
Rv2913c|M.tuberculosis_H37Rv DAVIVECPDKSLIG----------KSFGAIADERG-LHPLDAFLDVLVDN
MMAR_1795|M.marinum_M DAVIVECPDESLIG----------KSFGAIADERG-LHPLDAFLDVLVEN
MUL_2043|M.ulcerans_Agy99 DAVIVECPDESLIG----------KSFGAIADERG-LHPLDAFLDVLVEN
Mflv_3313|M.gilvum_PYR-GCK DAEIVACPDPAVIG----------KSFGEVGRDRGGLHPVDAFLDLVLEH
Mvan_3035|M.vanbaalenii_PYR-1 DAQIVACPDVSVIG----------KSFGEVGRERGGLHPVDAFLDLVLEH
MAB_2605c|M.abscessus_ATCC_199 DAEIVSCPDKSVLG----------KSFGQVGMDRGGLHPVDAFLDLVLEH
MSMEG_1997|M.smegmatis_MC2_155 DAEIVACPDPSVIG----------KSFGDVGVERGRLHPVDAFLDLVLEH
MAV_2959|M.avium_104 DAEIVACPEQAVVG----------KSFGQVGLERGGLHPVDAFLDLVVEH
TH_3974|M.thermoresistible__bu AFAQHAVDRLYPLGDPPDYEPTPDRTVTAIAAERG-VDPLTAMYDLMLEN
:* ::. :. :** :.*: *: *:::::
Mb2937c|M.bovis_AF2122/97 GERNVRWT--TIVANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFG
Rv2913c|M.tuberculosis_H37Rv GERNVRWT--TIVANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFG
MMAR_1795|M.marinum_M GERNVRWT--TVVANHRPKQLNKLAAEPGVHMGFSDAGAHLRNMAFYNFP
MUL_2043|M.ulcerans_Agy99 GERNVRWT--TVVANHRPKQLNKLAAEPGVHMGFSDAGAHLRNMAFYNFP
Mflv_3313|M.gilvum_PYR-GCK G-NELRWR--TTISNHRPEVLRKLAADSGIQMGFSDAGAHLRNMAFYNMG
Mvan_3035|M.vanbaalenii_PYR-1 G-KGLRWR--TTISNHRPEVLRKLAADPGIQMGFSDAGAHLRNMAFYNMG
MAB_2605c|M.abscessus_ATCC_199 G-TAMRWR--TTISNHRPEVLKQLAQDPGVQIGFSDAGAHLRNMAFYNFG
MSMEG_1997|M.smegmatis_MC2_155 G-SQLRWR--TTISNHRPKALRQLAVSSGIQVGFSDAGAHLRNMAFYNSG
MAV_2959|M.avium_104 G-ERLRWR--TTISNHRPEVLRKMAQSPTVQMGFSDAGAHLRNMAFYNSG
TH_3974|M.thermoresistible__bu GAGAMLLLPLYNYADGNHDAIREMLTHPAGVLGLSDGGAHCSMICDASYP
* : :: . . :.:: . :*:**.*** :. .
Mb2937c|M.bovis_AF2122/97 LRLLKRARDADRAGQPFLSIERAVYRLTGELAEWFGI-GAGTLRQGDRAD
Rv2913c|M.tuberculosis_H37Rv LRLLKRARDADRAGQPFLSIERAVYRLTGELAEWFGI-GAGTLRQGDRAD
MMAR_1795|M.marinum_M LRLLKRTWDAERAGKPFLSLQQAVYRLTGELAEWFGV-DAGTLREGDRAD
MUL_2043|M.ulcerans_Agy99 LRLLKRTWDAERAGKPFLSLQQAVYRLTGELAEWFGV-DAGTLREGDRAD
Mflv_3313|M.gilvum_PYR-GCK LRLLRHVQDAVRAGRPFMTIEAAVHRLTGELADWYRI-DAGHLRLGDRAD
Mvan_3035|M.vanbaalenii_PYR-1 LRLLRHVQDAARSGRPFMTVEQAVHRLTGELADWYRI-DAGHLRLGDRAD
MAB_2605c|M.abscessus_ATCC_199 LRLLRHVREAQQAGRPFMTVEQAVHRLTGELADWYQI-DAGHLRIGDRAD
MSMEG_1997|M.smegmatis_MC2_155 LRLLRHVRDAG-----FMSVEDAVYRLTGELADWYHL-DAGHLRMGDWAD
MAV_2959|M.avium_104 LRLLRHAHDAQKAGKPFISMEHAVHRLTGELGRWYGI-DAGTLRVGDRAD
TH_3974|M.thermoresistible__bu TFLLTHWARDRSRGD-RLPLEYVIRKQAHDTAQLFGLTDRGTIAVGKKAD
** : :.:: .: : : : . : : . * : *. **
Mb2937c|M.bovis_AF2122/97 FAVIDPTHLDESVDGYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFR
Rv2913c|M.tuberculosis_H37Rv FAVIDPTHLDESVDGYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFR
MMAR_1795|M.marinum_M FVVIDPAHLDESVDGYHEAQVPFYGGLSRMVNRNDATVIATGVAGAVVFG
MUL_2043|M.ulcerans_Agy99 FVVIDPAHLDESVDGYHEAQVPFYGGLSRMVNRNDATVIATGVAGAVVFG
Mflv_3313|M.gilvum_PYR-GCK IVILDPERLDASLDAYAEETVDQYGGLSRMVNRNDDTVSAVFVGGRAVFN
Mvan_3035|M.vanbaalenii_PYR-1 LVIVDPERLDDTLDRYAEEPVEQYGGLSRMVNRNDDTVAAVFVGGRAVFL
MAB_2605c|M.abscessus_ATCC_199 LFVIDPEKLDATLTAYAEESVDAYGGLSRMVNRNDATVSTVLIGGQPVVV
MSMEG_1997|M.smegmatis_MC2_155 VVVIDPQHLDAGLDEYHEAPVEAFGGMQRMVNRNDRTVKTVLVAGHTVFA
MAV_2959|M.avium_104 IVVIDPARLDESLDRYAEHPVASYGGLSRMVNRNDDTVTAVLVAGKLAFG
TH_3974|M.thermoresistible__bu LNVID---LDALTLHPPRMVYDLPAGGHRLVQG-ASGYVATIVGGVVTRR
. ::* ** . .* *:*: :. :.* .
Mb2937c|M.bovis_AF2122/97 GGQFGGQFRDGYGQNVKSGRYLRAGELGAALSRSA-------
Rv2913c|M.tuberculosis_H37Rv GGQFGGQFRDGYGQNVKSGRYLRAGELGAALSRSA-------
MMAR_1795|M.marinum_M S----GQFRDGYGQTVRSGRYLRAGQRYTAASVSA-------
MUL_2043|M.ulcerans_Agy99 T----GQFRDGYGQTVRSGRYLRAGQRYTAASVSA-------
Mflv_3313|M.gilvum_PYR-GCK G----GVPTPLVGE-HRTGRFLRAAHRVPALPATEGVLTHAG
Mvan_3035|M.vanbaalenii_PYR-1 D----GRPTPLVGA-ERTGRFLRAAHKAPALLAQNGALAHAG
MAB_2605c|M.abscessus_ATCC_199 D----GQLRDLLGK-RRTGRFLPAGAKARAVPVDTAPAPH--
MSMEG_1997|M.smegmatis_MC2_155 E----GTPTELVGR-RRTGSFMRADGRPRNAPLRRESVAV--
MAV_2959|M.avium_104 S----GRAAPQLGK-QRYGQFLRAGRPSRTLVSTG-------
TH_3974|M.thermoresistible__bu D---------GVDTGARPGRLVRGAR----------------
. : * : .