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VTYDVIIRDGLWFDGTGSAPQTRTLGIRDGMVATVSAGPLDETGCAQVIDAAGKWVMPGFIDVHTHYDAE VLLDPGLRESVRHGVTTVLLGNCSLSTVYAGAEDAADLFSRVEAVPRQFVLGALSAAKSERAWSNAAEYI TAIDSLPLGPNVSSLLGHSDLRATVLGLERATDASVRPSEAELGRMATLLDEALDAGMLGMSGMDSAIDK LDGERFRSRALPSTFATWRERRRLIKVLRKRGRILQSAPNVDKPASALLFFLASSRILNRRKGVRMSLLV SADSKSMPMAVRTFGLGARLLNKLLAASVRFQHLPVPFELYSDGIDLPVFEEFGAGTAALHLREQVQRNQ LLADESYRSEFRREFDRTKLGPSLWHKDFHDAVIVECPDESLIGKSFGAIADERGLHPLDAFLDVLVENG ERNVRWTTVVANHRPKQLNKLAAEPGVHMGFSDAGAHLRNMAFYNFPLRLLKRTWDAERAGKPFLSLQQA VYRLTGELAEWFGVDAGTLREGDRADFVVIDPAHLDESVDGYHEAQVPFYGGLSRMVNRNDATVIATGVA GAVVFGTGQFRDGYGQTVRSGRYLRAGQRYTAASVSA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2043 | - | - | 100% (597) | D-amino acid aminohydrolase |
| M. ulcerans Agy99 | MUL_1396 | - | 2e-32 | 27.75% (609) | D-amino acid aminohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2937c | - | 0.0 | 83.36% (601) | D-amino acid aminohydrolase |
| M. gilvum PYR-GCK | Mflv_3313 | - | 1e-102 | 57.89% (323) | hypothetical protein Mflv_3313 |
| M. tuberculosis H37Rv | Rv2913c | - | 0.0 | 83.36% (601) | D-amino acid aminohydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0680c | - | 0.0 | 67.52% (588) | hypothetical protein MAB_0680c |
| M. marinum M | MMAR_1795 | - | 0.0 | 99.33% (597) | D-amino acid aminohydrolase |
| M. avium 104 | MAV_3768 | - | 0.0 | 80.98% (594) | N-acyl-D-glutamate amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_6141 | - | 0.0 | 78.88% (587) | N-acyl-D-glutamate amidohydrolase |
| M. thermoresistible (build 8) | TH_3974 | - | 1e-37 | 27.52% (625) | PUTATIVE Amidohydrolase 3 |
| M. vanbaalenii PYR-1 | Mvan_3035 | - | 0.0 | 55.99% (593) | hypothetical protein Mvan_3035 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 -----MRALFDEPVTFDTIIRNGRWFDGTGAPSAVRNLGIRDGHVVSISE
MUL_2043|M.ulcerans_Agy99 -------------MTYDVIIRDGLWFDGTGSAPQTRTLGIRDGMVATVSA
MMAR_1795|M.marinum_M -------------MTYDVIIRDGLWFDGTGSAPQTRTLGIRDGVVATVSA
Mb2937c|M.bovis_AF2122/97 MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAA
Rv2913c|M.tuberculosis_H37Rv MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAA
MAV_3768|M.avium_104 -------------MPYDVIIRDGLWFDGTGGAALTRTLGIRDGVLVDVAE
MSMEG_6141|M.smegmatis_MC2_155 -------------MSYDVIVRNGLWFDGTGRPPQVRTLGIRDGVVATVSA
MAB_0680c|M.abscessus_ATCC_199 ------------MSVYDLIIRDGLWFDGTDSEPRKANLGIKEGRVATVST
TH_3974|M.thermoresistible__bu -------------MVFDLKITGGTVVDGTGADRFLGDIGIAGGTIVEVRR
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 DELDATGCP----QVIDAVGKWVLPGMLDIHTHYDIEVLGGPSLAESLRH
MUL_2043|M.ulcerans_Agy99 GPLDETGCA----QVIDAAGKWVMPGFIDVHTHYDAEVLLDPGLRESVRH
MMAR_1795|M.marinum_M GPLDETGCA----QVIDAAGKWVMPGFIDVHTHYDAEVLLDPGLRESVRH
Mb2937c|M.bovis_AF2122/97 GALDETGCP----EVVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRH
Rv2913c|M.tuberculosis_H37Rv GALDETGCP----EVVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRH
MAV_3768|M.avium_104 S-LDEAGCP----EVIDAAGKWVLPGFIDVHTHYDAEVLLDPGLRESVRH
MSMEG_6141|M.smegmatis_MC2_155 KPLDETGCP----EVIDAGGKWVVPGFIDVHTHYDAEVLLDPGLRESVRH
MAB_0680c|M.abscessus_ATCC_199 TALDETDCP----EVIDAGGKWVLPGFVDIHTHYDAEVLLNPGLDESVRH
TH_3974|M.thermoresistible__bu RGPGDPPLEGAAAETLDATGTIVAPGFVDIHTHYDGQVSWDDLLEPSSGH
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 GVTTVLLGSCSLSTVYVDGVDAGDIFGRVEAIPREHVIAAVDRHK---TW
MUL_2043|M.ulcerans_Agy99 GVTTVLLGNCSLSTVYAGAEDAADLFSRVEAVPRQFVLGALSAAKSERAW
MMAR_1795|M.marinum_M GVTTVLLGNCSLSTVYAGAEDAADLFSRVEAVPRQFVLGALSAAKSERAW
Mb2937c|M.bovis_AF2122/97 GVTTVLLGNCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQ---TW
Rv2913c|M.tuberculosis_H37Rv GVTTVLLGNCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQ---TW
MAV_3768|M.avium_104 GVTTVLLGNCSLSTVYADSQDAADLFSRVEAVPREYVYGALSSNR---TW
MSMEG_6141|M.smegmatis_MC2_155 GVTTVLLGMCSLSTVYSDAEDAADLFSRVEAVPRQFVLGALESRK---TW
MAB_0680c|M.abscessus_ATCC_199 GVTTIVLGCCSMSTVYAKPEDAADLFSRVEAVPRKHVIGALNEFQ---DW
TH_3974|M.thermoresistible__bu GVTTVVMGNCGVGFAPVRPGREEWLIELMEGV--EDIPGAALSEGISWGW
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 TTGEEYIAALESRPLGPNVAAFIGHSDMRTATMGLDRATRKDERPTGSEQ
MUL_2043|M.ulcerans_Agy99 SNAAEYITAIDSLPLGPNVSSLLGHSDLRATVLGLERATDASVRPSEAEL
MMAR_1795|M.marinum_M SNAAEYITAIDSLPLGPNVSSLLGHSDLRATVLGLERATDASVRPSEAEL
Mb2937c|M.bovis_AF2122/97 STPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDRATDDTVRPTEAEL
Rv2913c|M.tuberculosis_H37Rv STPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDRATDDTVRPTEAEL
MAV_3768|M.avium_104 STAADYVKAVDALPLGPNVGSLLGHSDLRAAVLGLDRATDATVRPTDAEL
MSMEG_6141|M.smegmatis_MC2_155 SNPAEYVAAIDALPLGPNIASLLGHSDLRASVLGLDRATTRGVVPTDDEL
MAB_0680c|M.abscessus_ATCC_199 TDPESYVKKIDALPLGPNVTSFLGHSDLRTAVMGLGRATNNWSFPTRKEL
TH_3974|M.thermoresistible__bu ESYADYLDVIGGRKLAIDVGSQIAHGTVRAYAMGERGARNEPATP--DDI
Mflv_3313|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3035|M.vanbaalenii_PYR-1 AQMERMLTEALRAGFVGMSSQQLLFDKLDGEVCRSRTLPSTYAKPRELRR
MUL_2043|M.ulcerans_Agy99 GRMATLLDEALDAGMLGMSGMDSAIDKLDGERFRSRALPSTFATWRERRR
MMAR_1795|M.marinum_M GRMATLLDEALDAGMLGMSGMDSAIDKLDGERFRSRALPSTFATWRERRR
Mb2937c|M.bovis_AF2122/97 AKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRERRK
Rv2913c|M.tuberculosis_H37Rv AKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRERRK
MAV_3768|M.avium_104 EKMAALLDEALDAGLLGMSGMDAAIDKLDGERFRSRALPSTFATWRERRK
MSMEG_6141|M.smegmatis_MC2_155 ETMADRLDAALDAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRERRR
MAB_0680c|M.abscessus_ATCC_199 DRMADMLDKALDAGMLGMSGMDAPIDKLDGDRYRSRALPSTYAWWHERWR
TH_3974|M.thermoresistible__bu AAMSRIVREAAEAGALGFSSS----RTLAHRAIDGEPVPGTFAAEDELFA
Mflv_3313|M.gilvum_PYR-GCK ------------------------------MFQS---LGIVRNPLKTSLL
Mvan_3035|M.vanbaalenii_PYR-1 LKSLLRRSG-RVLQSGPD--ITNPLNVASQVFQS---LGLVRNPLKTSLL
MUL_2043|M.ulcerans_Agy99 LIKVLRKRG-RILQSAPN--VDKPASALLFFLAS-SRILNRRKGVRMSLL
MMAR_1795|M.marinum_M LIKVLRKRG-RILQSAPN--VDKPASALLFFLAS-SRILNRRKGVRMSLL
Mb2937c|M.bovis_AF2122/97 LISVLRHRG-RILQSAPD--VDNPVSALLFFLAS-SRIFNRRKGVRMSML
Rv2913c|M.tuberculosis_H37Rv LISVLRHRG-RILQSAPD--VDNPVSALLFFLAS-SRIFNRRKGVRMSML
MAV_3768|M.avium_104 LIEVLRRRG-RILQSAPD--LDNPALALMFFLTS-SRIFGRGRGVRMSML
MSMEG_6141|M.smegmatis_MC2_155 LIKVLRKRG-RILQSAPN--VAKAQEALNFFLES-SSLFGRRRGVRMSLL
MAB_0680c|M.abscessus_ATCC_199 LINVLRKRD-RILQSAPN--INNPLTAVLFFLSTGTRFFKRRKAVPVSLL
TH_3974|M.thermoresistible__bu LGRALADGGGAVFELAPQGAAGEDIVAPGKELEWMRRLGAEIDCALSFAL
: : *
Mflv_3313|M.gilvum_PYR-GCK SAADVKS------NPVAVKLLGPLARLANR-LGGNFRWQH-LPVPFEVYA
Mvan_3035|M.vanbaalenii_PYR-1 SAADVKS------NPVAVKLLGPLARLANR-LGGNFRWQH-LPVPFEVYA
MUL_2043|M.ulcerans_Agy99 VSADSKS------MPMAVRTFGLGARLLNKLLAASVRFQH-LPVPFELYS
MMAR_1795|M.marinum_M VSADSKS------MPMAVHTFGLGARLLNKLLAASVRFQH-LPVPFELYS
Mb2937c|M.bovis_AF2122/97 VSADAKS------MPLAVHVFGLGTRVLNKLLGSQVRFQH-LPVPFELYS
Rv2913c|M.tuberculosis_H37Rv VSADAKS------MPLAVHVFGLGTRVLNKLLGSQVRFQH-LPVPFELYS
MAV_3768|M.avium_104 VSADAKS------MPLAVHTFGLGTRILNKLLRSSVRFQH-LPVPFELYS
MSMEG_6141|M.smegmatis_MC2_155 VSADAKS------SPGAARVIGMGTRLLNKTLDAKVRFQH-LPVPFELYS
MAB_0680c|M.abscessus_ATCC_199 VAADSKS------IKGANVFFSAAARIGNKVFKSNVKFQH-MPLPFTLYS
TH_3974|M.thermoresistible__bu IQVDADPNLWREQLEISAAAHEAGSRLYPQVAARPFGMLLGFPGHHAFTH
.* .. : :*: : . :* . .
Mflv_3313|M.gilvum_PYR-GCK DGIDLVIFEEFGSGAAALHLKDEVERNALLRDENYRREFRKDYD-AKFGM
Mvan_3035|M.vanbaalenii_PYR-1 DGIDLVIFEEFGSGAAALHLADEVDRNALLRDESYRRRFRKDYD-ARFGM
MUL_2043|M.ulcerans_Agy99 DGIDLPVFEEFGAGTAALHLREQVQRNQLLADESYRSEFRREFDRTKLGP
MMAR_1795|M.marinum_M DGIDLPVFEEFGAGTAALHLREQVQRNQLLADESYRREFRREFDRTKLGP
Mb2937c|M.bovis_AF2122/97 DGIDLPVFEEFGAGTAALHLRDQLQRNELLADRSYRRSFRREFDRIKLGP
Rv2913c|M.tuberculosis_H37Rv DGIDLPVFEEFGAGTAALHLRDQLQRNELLADRSYRRSFRREFDRIKLGP
MAV_3768|M.avium_104 DGIDLPVFEEFGAGTAALHLRDQLQRNELLADTDYRRRFRREFDRVKLGP
MSMEG_6141|M.smegmatis_MC2_155 DGIDLPVFEEFGAGTAALHLRDQLERNKLLADPEYRRRFRRSFDRRKLGP
MAB_0680c|M.abscessus_ATCC_199 DGIDLPVFEEFGAGTAALHIREQLDRNKLMADKEYRRKFRREFAIKKHKP
TH_3974|M.thermoresistible__bu RPTYRRLAAECDREELAARLAEPAVRAAILAEDDLPPDPDVLFD-GMFAF
: * . * :: : * :: : . :
Mflv_3313|M.gilvum_PYR-GCK RVWHRDFFDAEIVACPDPAVIGKSFGEVGRDRGGLHPVDAFLDLVLEHG-
Mvan_3035|M.vanbaalenii_PYR-1 RVWHRDFFDAQIVACPDVSVIGKSFGEVGRERGGLHPVDAFLDLVLEHG-
MUL_2043|M.ulcerans_Agy99 SLWHKDFHDAVIVECPDESLIGKSFGAIADERG-LHPLDAFLDVLVENGE
MMAR_1795|M.marinum_M SLWHKDFHDAVIVECPDESLIGKSFGAIADERG-LHPLDAFLDVLVENGE
Mb2937c|M.bovis_AF2122/97 SLWHRDFHDAVIVECPDKSLIGKSFGAIADERG-LHPLDAFLDVLVDNGE
Rv2913c|M.tuberculosis_H37Rv SLWHRDFHDAVIVECPDKSLIGKSFGAIADERG-LHPLDAFLDVLVDNGE
MAV_3768|M.avium_104 SLWHRDFHDAVIVECPDKSLIGKSFGAIADERG-LHPLDAFLDVLVENGE
MSMEG_6141|M.smegmatis_MC2_155 TLWHRDFHDATIVECPDESLIGKTFGRIADERG-IHPLDAFLDVLVDNGE
MAB_0680c|M.abscessus_ATCC_199 GLWHKDFHDAVIVECPDASLVGKTFGQIGDERG-IAPLDAFLDVLVDNGE
TH_3974|M.thermoresistible__bu AQHAVDRLYPLGDPPDYEPTPDRTVTAIAAERG-VDPLTAMYDLMLENGA
* . . .::. :. :** : *: *: *:::::*
Mflv_3313|M.gilvum_PYR-GCK NELRWRTTISNHR--PEVLRKLAADSGIQMGFSDAGAHLRNMAFYNMGLR
Mvan_3035|M.vanbaalenii_PYR-1 KGLRWRTTISNHR--PEVLRKLAADPGIQMGFSDAGAHLRNMAFYNMGLR
MUL_2043|M.ulcerans_Agy99 RNVRWTTVVANHR--PKQLNKLAAEPGVHMGFSDAGAHLRNMAFYNFPLR
MMAR_1795|M.marinum_M RNVRWTTVVANHR--PKQLNKLAAEPGVHMGFSDAGAHLRNMAFYNFPLR
Mb2937c|M.bovis_AF2122/97 RNVRWTTIVANHR--PNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLR
Rv2913c|M.tuberculosis_H37Rv RNVRWTTIVANHR--PNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLR
MAV_3768|M.avium_104 RNVRWTTTVANHR--PKQLDKLAADPSIHMGFSDAGAHLRNMAFYNFALR
MSMEG_6141|M.smegmatis_MC2_155 KNVRWTTIVANHR--PKVLDQLANDPAVHMGFSDAGAHLRNMAFYNYPLR
MAB_0680c|M.abscessus_ATCC_199 KNVRWTTTVGNHR--PKVLDEMAKDPNFQLGFSDAGAHLRNMAFYNFSLR
TH_3974|M.thermoresistible__bu GAMLLLPLYNYADGNHDAIREMLTHPAGVLGLSDGGAHCSMICDASYPTF
: . . : :: .. :*:**.*** :. .
Mflv_3313|M.gilvum_PYR-GCK LLRHVQDAVRAGRPFMTIEAAVHRLTGELADWYR-IDAGHLRLGDRADIV
Mvan_3035|M.vanbaalenii_PYR-1 LLRHVQDAARSGRPFMTVEQAVHRLTGELADWYR-IDAGHLRLGDRADLV
MUL_2043|M.ulcerans_Agy99 LLKRTWDAERAGKPFLSLQQAVYRLTGELAEWFG-VDAGTLREGDRADFV
MMAR_1795|M.marinum_M LLKRTWDAERAGKPFLSLQQAVYRLTGELAEWFG-VDAGTLREGDRADFV
Mb2937c|M.bovis_AF2122/97 LLKRARDADRAGQPFLSIERAVYRLTGELAEWFG-IGAGTLRQGDRADFA
Rv2913c|M.tuberculosis_H37Rv LLKRARDADRAGQPFLSIERAVYRLTGELAEWFG-IGAGTLRQGDRADFA
MAV_3768|M.avium_104 MLKRTRDAQAAGAPFLTIERAVHRLTGELADWFG-IDAGTLRPGDRADFV
MSMEG_6141|M.smegmatis_MC2_155 LLKRVRDAQLSGRPFLTTERAVYRLTAEVADWFG-VDAGTLREGDRADFV
MAB_0680c|M.abscessus_ATCC_199 FLKRMNDAQKAGKPVMSLGQAVHRLTGELASWFG-LDAGYLREGDRADFV
TH_3974|M.thermoresistible__bu LLTHWARDRSRGD-RLPLEYVIRKQAHDTAQLFGLTDRGTIAVGKKADLN
:* : * :. .: : : : *. : . * : *.:**:
Mflv_3313|M.gilvum_PYR-GCK ILDPERLDASLDAYAEETVDQYGGLSRMVNRNDDTVSAVFVGGRAVFNGG
Mvan_3035|M.vanbaalenii_PYR-1 IVDPERLDDTLDRYAEEPVEQYGGLSRMVNRNDDTVAAVFVGGRAVFLDG
MUL_2043|M.ulcerans_Agy99 VIDPAHLDESVDGYHEAQVPFYGGLSRMVNRNDATVIATGVAGAVVFGTG
MMAR_1795|M.marinum_M VIDPAHLDESVDGYHEAQVPFYGGLSRMVNRNDATVIATGVAGAVVFGSG
Mb2937c|M.bovis_AF2122/97 VIDPTHLDESVDGYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFRGG
Rv2913c|M.tuberculosis_H37Rv VIDPTHLDESVDGYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFRGG
MAV_3768|M.avium_104 VIDPAGLDESVDAYHEEAVPFYGGLRRMINRNDDAVVATGVGGVVVFGGS
MSMEG_6141|M.smegmatis_MC2_155 VIDPNCLNSDVDAYHEETVPFYGGLSRMVNRNDDAVVATAVNGTVVFGKG
MAB_0680c|M.abscessus_ATCC_199 IIDPEKLDGTVDAYNEAQAPFFDNLSRMVNRNDETVVATAVGGKVVFRLG
TH_3974|M.thermoresistible__bu VID---LDALTLHPPRMVYDLPAGGHRLVQG-ASGYVATIVGGVVTRRDG
::* *: . . *::: *. * * .. .
Mflv_3313|M.gilvum_PYR-GCK -----VPTPLVGEHRTGRFLRAAHRVPALPATEGVLTHAG
Mvan_3035|M.vanbaalenii_PYR-1 -----RPTPLVGAERTGRFLRAAHKAPALLAQNGALAHAG
MUL_2043|M.ulcerans_Agy99 ----QFRDGYGQTVRSGRYLRAGQRYTAAS----VSA---
MMAR_1795|M.marinum_M ----QFRDGYGQTVRSGRYLRAGQRYTAAS----VSA---
Mb2937c|M.bovis_AF2122/97 QFGGQFRDGYGQNVKSGRYLRAGELGAALS----RSA---
Rv2913c|M.tuberculosis_H37Rv QFGGQFRDGYGQNVKSGRYLRAGELGAALS----RSA---
MAV_3768|M.avium_104 HRKGEFRDGYGHTVKSGRYLRAGQRVRAKGGAPRVTA---
MSMEG_6141|M.smegmatis_MC2_155 ----EFRDGYGDTVKSGRYLRAGADSRLKT-----AV---
MAB_0680c|M.abscessus_ATCC_199 ----EFIEGYGHDLQTGRYLKAGEKLALR-----------
TH_3974|M.thermoresistible__bu ---------VDTGARPGRLVRGAR----------------
:.** ::..