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DFGVVLQCDPPAVRTVQLAKLAEAHGFSHLWTFDSHLLWQEPYVLYSQILHETRRIVVGPMVTNPATRDW TVTASLYATLNDMYGNRTICGIGRGDSAVRVTGGTPTTLATLRESIHVIRELANSRPVEYHGATMQFPWS RGSELDVWVAAYGPKALALAGQVADGFILQLADIDIARWMIGAVREAAVAAGRDPAAVRICVAAPMYVGS DRTHMRAQCRWFGGMVGNHVADIVARYGSQGDVPQTLTAYIAGRDGYDYNQHGRAGNTHAEFVSDDIVDR FCVLGTADEHIAKLSELKALGVDQFAGYLQHDNKEETLRVYGETVIPALSQHITAKSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2816c | - | - | 100% (339) | putative luciferase-like protein |
| M. abscessus ATCC 19977 | MAB_4230c | - | 4e-11 | 28.08% (203) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4166c | - | 2e-10 | 26.10% (341) | putative luciferase-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0137c | fgd2 | 8e-15 | 27.72% (267) | putative f420-dependant glucose-6-phosphate dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0211 | - | 4e-12 | 27.80% (205) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0132c | fgd2 | 5e-15 | 27.72% (267) | putative f420-dependent glucose-6-phosphate dehydrogenase |
| M. leprae Br4923 | MLBr_00269 | - | 4e-13 | 22.58% (341) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. marinum M | MMAR_4003 | - | 3e-12 | 33.33% (156) | oxidoreductase |
| M. avium 104 | MAV_5061 | - | 2e-17 | 27.96% (304) | hypothetical protein MAV_5061 |
| M. smegmatis MC2 155 | MSMEG_3554 | - | 1e-131 | 65.36% (332) | N5,N10-methylene- tetrahydromethanopterin reductase |
| M. thermoresistible (build 8) | TH_1683 | - | 1e-11 | 28.78% (205) | PROBABLE F420-DEPENDENT GLUCOSE-6-PHOSPHATE DEHYDROGENASE FGD1 |
| M. ulcerans Agy99 | MUL_3866 | - | 1e-12 | 33.97% (156) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0698 | - | 9e-12 | 27.32% (205) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2816c|M.abscessus_ATCC_199 -----------------------------------------MDFGVVLQC
MSMEG_3554|M.smegmatis_MC2_155 -----------------------------------------MHFGIVLQP
Mflv_0211|M.gilvum_PYR-GCK --------------------------------------MAELKLGYKASA
Mvan_0698|M.vanbaalenii_PYR-1 --------------------------------------MAELKLGYKASA
MLBr_00269|M.leprae_Br4923 --------------------------------------MAELRLGYKASA
TH_1683|M.thermoresistible__bu ---------------------------------------VNLKLGYKASA
Mb0137c|M.bovis_AF2122/97 MTGISRRTFGLAAGFGAIGAGGLGGGCSTRSGPTPTPEPASRGVGVVLSH
Rv0132c|M.tuberculosis_H37Rv MTGISRRTFGLAAGFGAIGAGGLGGGCSTRSGPTPTPEPASRGVGVVLSH
MMAR_4003|M.marinum_M ---------------------------------MSDRTLNELGYYLLAGA
MUL_3866|M.ulcerans_Agy99 ---------------------------------MSDRTLNELGYYLLAGA
MAV_5061|M.avium_104 -------------------------------------MVSHLPADRVDET
MAB_2816c|M.abscessus_ATCC_199 DPPAVR-TVQLAKLAEAHGFSHLWTFDSHLLWQEP-------YVLYSQIL
MSMEG_3554|M.smegmatis_MC2_155 DPPASR-VVELAVAAENRGFDYVWTFDSHLLWQEP-------YVIHSQIL
Mflv_0211|M.gilvum_PYR-GCK EQFAPRELVELAVAAEEHGMDSATVSDHFQPWRHEGGHAPFSLAWMTAVG
Mvan_0698|M.vanbaalenii_PYR-1 EQFAPRELVELAVAAEEHGMDSATVSDHFQPWRHEGGHAPFSLAWMTAVG
MLBr_00269|M.leprae_Br4923 EQFAPRELVELGVAAEAHGMDSATVSDHFQPWRHQGGHASFSLSWMTAVG
TH_1683|M.thermoresistible__bu EQFSPRELVELGVLAEAHGMDSAAVSDHFQPWRHNGGHAPFALAWMAAVG
Mb0137c|M.bovis_AF2122/97 EQFRTDRLVAHAQAAEQAGFRYVWASDHLQPWQDNEGHSMFPWLTLALVG
Rv0132c|M.tuberculosis_H37Rv EQFRTDRLVAHAQAAEQAGFRYVWASDHLQPWQDNEGHSMFPWLTLALVG
MMAR_4003|M.marinum_M GGEGPATLMDEARRGEELGLGTAFVSERWNVKEAS--------SLVGAAC
MUL_3866|M.ulcerans_Agy99 GGEGPATLMDEARRGEELGLGTAFVSERWNVKEAS--------SLVGAAC
MAV_5061|M.avium_104 GARTVAQGIEDGVAAERLGFANVYLSERWNLKEAG--------VVLGAIG
: . .* *: : .
MAB_2816c|M.abscessus_ATCC_199 HETRRIVVGPMVTNPATR-DWTVTASLYATLNDMYGNRTICGIGRGDSAV
MSMEG_3554|M.smegmatis_MC2_155 SATRNVMVGPMVTNPLSR-DVTVTASTHATLNSMFGNRTVCSIGRGDSAV
Mflv_0211|M.gilvum_PYR-GCK ERTTRLQLGTSVLTPTFRYNPAVIAQAFATMGCLYPDRIFLGVGTGEALN
Mvan_0698|M.vanbaalenii_PYR-1 ERTKRLQLGTSVLTPTFRYNPAVIAQAFATMGCLYPGRIFLGVGTGEALN
MLBr_00269|M.leprae_Br4923 ERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTGEALN
TH_1683|M.thermoresistible__bu ERTTTLALGTSVLTPTFRYNPAVIAQAFATMGCLFPGRIMLGVGTGEALN
Mb0137c|M.bovis_AF2122/97 NSTSSILFGTGVTCPIYRYHPATVAQAFASLAILNPGRVFLGLGTGKRLN
Rv0132c|M.tuberculosis_H37Rv NSTSSILFGTGVTCPIYRYHPATVAQAFASLAILNPGRVFLGLGTGERLN
MMAR_4003|M.marinum_M AVTSRMQIATAATNHNTR-HPLVTASWATTMHRLSGGRFTLGIGRGIAAI
MUL_3866|M.ulcerans_Agy99 AVTSRMQIATAATNHNTR-HPVVTASWATTMHRLSGGRFTLGIGRGIAAI
MAV_5061|M.avium_104 ARTTRVGLGTGLVSPARR-HVLHMAALGATIHAAVGPRFLLGLGRGDHAY
* : ... * . . ::: * .:* *
MAB_2816c|M.abscessus_ATCC_199 RVTGGTP-------TTLATLRESIHVIRELANSRPVE-YHGATMQFPWS-
MSMEG_3554|M.smegmatis_MC2_155 RTLSGKP-------SSLATLRAAVKVISDLGNGRPTE-INGTTVQIPWA-
Mflv_0211|M.gilvum_PYR-GCK EIATGYEGEWPEFKERYARLRESVRLMRELWLGDRVD-FEGEYYKTKGAS
Mvan_0698|M.vanbaalenii_PYR-1 EIATGYEGDWPEFKERYARLRESVRLMRDLWLGDRVD-FEGEYYKTKGAS
MLBr_00269|M.leprae_Br4923 EVATGYQGAWPEFKERFARLRESVRLMRELWRGDRVD-FDGDYYQLKGAS
TH_1683|M.thermoresistible__bu EIATGGAGEWPRFTERFARLREAVTLMRALWSGDRVD-FDGDYYTARGAS
Mb0137c|M.bovis_AF2122/97 EQAATDT--FGNYRERHDRLIEAIVLIRQLWSGERIS-FTGHYFRTDELK
Rv0132c|M.tuberculosis_H37Rv EQAATDT--FGNYRERHDRLIEAIVLIRQLWSGERIS-FTGHYFRTDELK
MMAR_4003|M.marinum_M YGAFGIP------AVTTAQMEDWAQVMRRLWKGEMIFNHDGPMGRYPVLF
MUL_3866|M.ulcerans_Agy99 YGAFGIP------AVTTAQMEDWAQVMRRLWKGEMVFNHDGPMGRYPVLF
MAV_5061|M.avium_104 LRHEGLK------TAGFAAVVDYVKIMRRLWDGEAVT-YDGPAGNYRNIK
: :: * . *
MAB_2816c|M.abscessus_ATCC_199 ----RGSELDVWVAAYG--PKALALAGQVADGFILQLAD--IDIARWMIG
MSMEG_3554|M.smegmatis_MC2_155 ----SKSTLDVYVGAYG--PRALDLCGQVADGFLLQLAD--PDITKWMIE
Mflv_0211|M.gilvum_PYR-GCK IYDVPEGGIPIYIAAGG--PQVAKYAGRAGDGFICTSGKGEELYKEKLIP
Mvan_0698|M.vanbaalenii_PYR-1 IYDVPEGGIPIYIAAGG--PQVAKYAGRAGDGFICTSGKGEELYKDKLIP
MLBr_00269|M.leprae_Br4923 IYDVPEGGVPIYIAAGG--PEVAKYAGRAGEGFVCTSGKGEELYTEKLIP
TH_1683|M.thermoresistible__bu IYDVPDDGIPVYIAAGG--PTVARYAGTAGDGFICTSGKGMDLYTQKLMP
Mb0137c|M.bovis_AF2122/97 LYDTPAMPPPIFVAASG--PQSATLAGRYGDGWIAQAR---DINDAKLLA
Rv0132c|M.tuberculosis_H37Rv LYDTPAMPPPIFVAASG--PQSATLAGRYGDGWIAQAR---DINDAKLLA
MMAR_4003|M.marinum_M LDPDFNEDIRLALVALG--PKSLALGGRVFDDVILHTYFT-PETLQRCVS
MUL_3866|M.ulcerans_Agy99 LDPDFNEDIRLALVALG--PKSLALGGRVFDDVILHTYFT-PETLQRCVS
MAV_5061|M.avium_104 LGDIYQGPAPQVLYGTFGMPKAAAAVAEAFDGVILPPMMS-PSATTASVG
: . * . :. : :
MAB_2816c|M.abscessus_ATCC_199 AVREAAVAAGRDPAAVRICVAAPMY--VGSDRTHMRAQCRWFGGMVGNHV
MSMEG_3554|M.smegmatis_MC2_155 RVKNAAADAGRNPDDIKVCVGAPAY--IGDDLEHQRDQCRWFGGMVGNHV
Mflv_0211|M.gilvum_PYR-GCK AMREGAEAAGKNPDDVDRMIEIKIS--YDTDPELALENTRFWAPLS----
Mvan_0698|M.vanbaalenii_PYR-1 AMREGAEAAGKNPDDIDRMIEIKIS--YDTDPELALENTRFWAPLS----
MLBr_00269|M.leprae_Br4923 AVLEGAAVAGRDADDIDKMIEIKMS--YDPDPEQALSNIRFWAPLS----
TH_1683|M.thermoresistible__bu AVTEGARAAGREPDQIDRMIEIKIS--YDPDPAQALENTRFWAPLS----
Mb0137c|M.bovis_AF2122/97 AFAAGAQAAGRDPTTLGKRAELFAV--VGDD-KAAARAADLWRFTA----
Rv0132c|M.tuberculosis_H37Rv AFAAGAQAAGRDPTTLGKRAELFAV--VGDD-KAAARAADLWRFTA----
MMAR_4003|M.marinum_M IVKTAADRAGRDPASVR-VWSCFAT--VGDHLPEQLRLKKTVARLATYLQ
MUL_3866|M.ulcerans_Agy99 IVKTAADRAGRDPASVR-VWSCFAT--VGDHLPEQLRLKKTVARLATYLQ
MAV_5061|M.avium_104 RLRRACEAIGRDPATLRVVQCVVTAPDLSVDETRALAHARAVTYLQAPEY
. .. *::. : . .
MAB_2816c|M.abscessus_ATCC_199 ADIVARYGSQGDVPQTLTAYIAGRDGYDYNQHGRAGNTHAEFVSDDIVDR
MSMEG_3554|M.smegmatis_MC2_155 ADIVARYGSSGAVPQALTEYIKGRVGYDYNEHGRAGNSHADFVPDEIVDR
Mflv_0211|M.gilvum_PYR-GCK --------------------LTAEQKHSIDDPMEMEKAADELPIEQVAKR
Mvan_0698|M.vanbaalenii_PYR-1 --------------------LTAEQKHSIDDPIEMEKAADALPIEQVAKR
MLBr_00269|M.leprae_Br4923 --------------------LAAEQKHSIDDPIEMEKVADALPIEQVAKR
TH_1683|M.thermoresistible__bu --------------------LTPEQKHSIDDPVEMERIADRLPIEQIARR
Mb0137c|M.bovis_AF2122/97 --------------------GAVDQ----PNPVEIQRAAESNPIEKVLAN
Rv0132c|M.tuberculosis_H37Rv --------------------GAVDQ----PNPVEIQRAAESNPIEKVLAN
MMAR_4003|M.marinum_M G-----YGDLLVHTNNWDPAVLQRFREDPVVTSVRGGIDHKATAEQIEHI
MUL_3866|M.ulcerans_Agy99 G-----YGDLLVHTNNWDPAVLQRFREDPVVTSVRGGIDHKATAEQIEHI
MAV_5061|M.avium_104 G-----AALARVNGWSLAPVERLRAAVAKVKSAGDELVDTAFHRIQLMDL
.:
MAB_2816c|M.abscessus_ATCC_199 FCVLGTADEHIA-KLSELKALGVDQFAGYLQHDNKEETLRVYGETVIPAL
MSMEG_3554|M.smegmatis_MC2_155 FCILGPAPAHIS-KLQELQKLGVDQFAIYLQHDGQDHTLAEYGRAIIPVI
Mflv_0211|M.gilvum_PYR-GCK WIVASDPDEAVA-KVADYVDYGLNHLVFHAPGHDQRRFLELFQRDLEPRL
Mvan_0698|M.vanbaalenii_PYR-1 WIVASDPDEAVA-KVKDYVDWGLNHLVFHAPGHDQRRFLELFRRDLEPRL
MLBr_00269|M.leprae_Br4923 WIVVSDPDEAVA-RVGQYVTWGLNHLVFHAPGHNQRRFLELFEKDLAPRL
TH_1683|M.thermoresistible__bu WIVASDPDQAVD-EIKQYVDAGFNHLVFHAPGSDQPRFLTLFEKDLAPRL
Mb0137c|M.bovis_AF2122/97 WAVGTDPGVHIG-AVQAVLDAG-AVPFLHFPQDDPITAIDFYRTNVLPEL
Rv0132c|M.tuberculosis_H37Rv WAVGTDPGVHIG-AVQAVLDAG-AVPFLHFPQDDPITAIDFYRTNVLPEL
MMAR_4003|M.marinum_M ATLLPDEWLEPS-ATGSAQQCVDRIRAEFGYGADAVIMHGATPDELEPVV
MUL_3866|M.ulcerans_Agy99 ATLLPDEWLEPS-ATGSAQQCVDRIRAEFGYGADAVIMHGATPDELEPVV
MAV_5061|M.avium_104 ADMVPDEWMEASCAFGTAAQCARKLQEFKRAGADEIATYGSTPSQNAGVL
: . :
MAB_2816c|M.abscessus_ATCC_199 SQHITAKSG---
MSMEG_3554|M.smegmatis_MC2_155 NRPADAILT---
Mflv_0211|M.gilvum_PYR-GCK RKLG--------
Mvan_0698|M.vanbaalenii_PYR-1 RKLG--------
MLBr_00269|M.leprae_Br4923 RRLG--------
TH_1683|M.thermoresistible__bu RSLQ--------
Mb0137c|M.bovis_AF2122/97 R-----------
Rv0132c|M.tuberculosis_H37Rv R-----------
MMAR_4003|M.marinum_M AAYRQKAQ----
MUL_3866|M.ulcerans_Agy99 AAYRQKAQ----
MAV_5061|M.avium_104 AAWSDAFAGDMR