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MSIAESANASVRTGPAPSSKTREFARAILSGTAVHPEEIPAGRAYTTLRDLATHPGLRDVTDVLIPGSAP DTVDFLPLARLVNAAELPAIRAAIDSVLPSGKFTSGPHVDAFEDEIATYLGIDHVIGASSGTDAMTAVLL ALGAGPGTEVILPANSFAATENAVFLTGARPVLVDTRADDHLLDPTEVEAAITSRTVAVLPVHLYGAFAD IHALTEVTSRHGIPVVEDGCQGIGLDGLGHHSDAAILSFNPYKNLGAVGKAGAVATRLPGLARRVTELLY HGFAAGQKNVKAAGYGLNSRLDNLQAAVLRARLDWLGENNLARSILARRYVDGLADLAESGLLRLPHWDT DHVWHLFTVEVTKHDRDKVTESLRAAGVATDLYYPVLTHRHRVPLVADLFEGVRLPRTEAAHARMFQLPL YPTLTLAEQDRVIGVLHDVLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2610 | - | - | 100% (441) | putative aminotransferase |
| M. abscessus ATCC 19977 | MAB_2687c | - | 3e-08 | 29.55% (176) | 8-amino-7-oxononanoate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1542c | - | 2e-23 | 29.91% (331) | TDP-4-oxo-6-deoxy-D-glucose transaminase |
| M. gilvum PYR-GCK | Mflv_3628 | - | 2e-06 | 29.77% (131) | 8-amino-7-oxononanoate synthase |
| M. tuberculosis H37Rv | Rv1504c | - | 2e-18 | 38.85% (139) | hypothetical protein Rv1504c |
| M. leprae Br4923 | MLBr_01217 | bioF | 6e-05 | 30.77% (130) | 8-amino-7-oxononanoate synthase |
| M. marinum M | MMAR_2320 | wecE | 8e-22 | 31.12% (331) | pyridoxal phosphate-dependent enzyme, WecE |
| M. avium 104 | MAV_3205 | bioF | 4e-06 | 31.82% (132) | 8-amino-7-oxononanoate synthase |
| M. smegmatis MC2 155 | MSMEG_3189 | bioF | 1e-08 | 32.09% (134) | 8-amino-7-oxononanoate synthase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2789 | - | 3e-08 | 32.33% (133) | 8-amino-7-oxononanoate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01217|M.leprae_Br4923 MKVPIETSPLAWLEAVEQQRRGAGLRRSLRPRSAVATELDLASNDYLGL-
MAV_3205|M.avium_104 MKAPIEVSPLAWLDAVEQQRRAAGLRRSLRPRPPVATELDLASNDYLGL-
Mflv_3628|M.gilvum_PYR-GCK -MTRAGLSPLAWLDEVETQRRAAGLRRSLRARPPVGTVLDLASNDYLGL-
Mvan_2789|M.vanbaalenii_PYR-1 -MTRVSLSPLAWLDEVETQRRAAGLRRTVRTRPPVGAELDLASNDYLGL-
MSMEG_3189|M.smegmatis_MC2_155 -MTRAGLSPLAWLADIEQRRRAEGLRRELRVRPPVAAELDLASNDYLGL-
Mb1542c|M.bovis_AF2122/97 -MSDHKVP----FNRPYMTGRELAYIAEAHSCGHLAGDGPFTRRSHAWL-
Rv1504c|M.tuberculosis_H37Rv -MSDHKVP----FNRPYMTGRELAYIAEAHSCGHLAGDGPFTRRSHAWL-
MMAR_2320|M.marinum_M -MVEHKIP----FNRPYMTGQELNYIAEAHSCGHLAGDGPFTYRCHAWL-
MAB_2610|M.abscessus_ATCC_1997 -MSIAESANASVRTGPAPSSKTREFARAILSGTAVHPEEIPAGRAYTTLR
. : : : . : *
MLBr_01217|M.leprae_Br4923 --SQHPDVIDGGVAALRV--------------------------------
MAV_3205|M.avium_104 --SQHPDVIDGGVAALRL--------------------------------
Mflv_3628|M.gilvum_PYR-GCK --SQHPRVIDGGVAALRT--------------------------------
Mvan_2789|M.vanbaalenii_PYR-1 --SQHPRVIDGGVSALRT--------------------------------
MSMEG_3189|M.smegmatis_MC2_155 --SQHPDVLDGGVEALRT--------------------------------
Mb1542c|M.bovis_AF2122/97 --EQQTGCRK---ALLTP--------------------------------
Rv1504c|M.tuberculosis_H37Rv --EQQTGCRK---ALLTP--------------------------------
MMAR_2320|M.marinum_M --EQQTGCRK---ALLTP--------------------------------
MAB_2610|M.abscessus_ATCC_1997 DLATHPGLRDVTDVLIPGSAPDTVDFLPLARLVNAAELPAIRAAIDSVLP
:. . :
MLBr_01217|M.leprae_Br4923 ------------------------------WGAGATGSRLVTGDTILHHE
MAV_3205|M.avium_104 ------------------------------WGAGATGSRLVTGDTELHQQ
Mflv_3628|M.gilvum_PYR-GCK ------------------------------WGAGATGSRLVTGNTELHEQ
Mvan_2789|M.vanbaalenii_PYR-1 ------------------------------WGAGSTGSRLVTGNTELHEA
MSMEG_3189|M.smegmatis_MC2_155 ------------------------------WGGGAGGSRLVTGNTELHEA
Mb1542c|M.bovis_AF2122/97 ------------------------------SCTAALEMMALLLDIEEGDE
Rv1504c|M.tuberculosis_H37Rv ------------------------------SCTAALEMMALLLDIEEGDE
MMAR_2320|M.marinum_M ------------------------------SCTAALEMMALLLEIEEGDE
MAB_2610|M.abscessus_ATCC_1997 SGKFTSGPHVDAFEDEIATYLGIDHVIGASSGTDAMTAVLLALGAGPGTE
: :
MLBr_01217|M.leprae_Br4923 LECELAEFVGACVGLLFSSGYAANLGAVVGLSGPGSLIVSDAYSHAS---
MAV_3205|M.avium_104 FESELADYVGAASGLLFSSGYAANLGAVVGLSGRGALVVSDAYSHAS---
Mflv_3628|M.gilvum_PYR-GCK FEDALASFVGADSALVFSSGYTANLGAVVALSGPGSLLVSDAYTHAS---
Mvan_2789|M.vanbaalenii_PYR-1 FEDVLAAFVGAESALVFSSGYTANLGAVVALSGPGSLLVSDANTHAS---
MSMEG_3189|M.smegmatis_MC2_155 FEHQLASFLGAESALVFSSGYTANLGALVALSGPGSLIVSDALSHAS---
Mb1542c|M.bovis_AF2122/97 VILPSYTFVSTANAFVLRGGVPVFVDIRPDTLNIDETRIVDAITPRTKAI
Rv1504c|M.tuberculosis_H37Rv VILPSYTFVSTANAFVLRGGVPVFVDIRPDTLNIDETRIVDAITPRTKAI
MMAR_2320|M.marinum_M VILPSFTFVSTANAFVLRGGVPVFVDIRPDTLNVDETLIEAAITPRTRAI
MAB_2610|M.abscessus_ATCC_1997 VILPANSFAATENAVFLTGARPVLVDTRADDHLLDPTEVEAAITSRTVAV
. : .: ...: .. .. :. . : * : :
MLBr_01217|M.leprae_Br4923 -----LVDACRLSRARVVVTPHCDVDAVDTALRSCHEERAVVVTESVFSA
MAV_3205|M.avium_104 -----LVDACRLSRARVVVTPHRDVDAVLAALADRDEERAVVITESVFST
Mflv_3628|M.gilvum_PYR-GCK -----LVDACRLSRARVVVTPHNDVAAVARALATRDEERAVVVTDSVFSA
Mvan_2789|M.vanbaalenii_PYR-1 -----LVDACRLSRARVVVTPHNDTAAVEQALATRSEARAVVVTDSVFSA
MSMEG_3189|M.smegmatis_MC2_155 -----LVDACRLSRARVVVSPHRDVDAVDAALAARTEERAVVVTESVFSA
Mb1542c|M.bovis_AF2122/97 VPVHYAGVACEMDAIMKIATHHNLAVVEDAAQGAMASYRGRALGS--IGD
Rv1504c|M.tuberculosis_H37Rv VPVHYAGVACEMDAIMKIATHHNLAVVEDAAQGAMASYRGRALGS--IGD
MMAR_2320|M.marinum_M VPVHYAGVACEMDTIMSIARRHKLAVVEDAAQGTMAYYRGRALGS--IGD
MAB_2610|M.abscessus_ATCC_1997 LPVHLYGAFADIHALTEVTSRHGIPVVEDGCQGIGLDG----LGHHSDAA
. : :. * . . : .
MLBr_01217|M.leprae_Br4923 DGVLAPVSELHDVCRRHGALLLVDEAHGLGVRG-GGRGLVYEVGLAGAPD
MAV_3205|M.avium_104 DGALAPLRELHEVCRRHRALLIVDEAHGLGVRG-GGRGLVFEAGLAGAPD
Mflv_3628|M.gilvum_PYR-GCK DGDLAPLRELHDACRRHGALMIVDEAHGLGVRGDRGRGLLDEVGLAGAPD
Mvan_2789|M.vanbaalenii_PYR-1 DGDLAPLRALHTACRKHGALLIVDEAHGLGVRGDGGRGLLDEVGLAGAPD
MSMEG_3189|M.smegmatis_MC2_155 DGDLAPLRDLHAVCRRHGALLLVDEAHGLGVRGTRGQGLLHEVGLAGAPD
Mb1542c|M.bovis_AF2122/97 LGALSFHETKNVISGEGGALLVNSEDFLLRAEILREKGTNRSRFLRNEVD
Rv1504c|M.tuberculosis_H37Rv LGALSFHETKNVISGEGGALLVNS--------------------------
MMAR_2320|M.marinum_M LGALSFHETKNVISGEGGALLVNSEEYIYRAEILRDKGTNRSRFLRKEVD
MAB_2610|M.abscessus_ATCC_1997 ILSFNPYKNLGAVG-KAGAVATRLPGLARRVTELLYHGFAAGQKNVKAAG
: . *:
MLBr_01217|M.leprae_Br4923 VVITTTMSKALGS--QGGAVLGSSAVRAHLINTARPFIFDTGLAPAAVGA
MAV_3205|M.avium_104 VVMTTTLSKALGS--QGGAVLGPAAVRAHLIDAARTFIFDTGLAPAAVGA
Mflv_3628|M.gilvum_PYR-GCK VVMTTTLSKALGS--QGGVVLGPAAVRDHLIDAARPFIFDTGLAPAAVGA
Mvan_2789|M.vanbaalenii_PYR-1 LVMTTTLSKALGS--QGGVVLGPAAVRAHLIDTARPFIFDTGLAPAAVGA
MSMEG_3189|M.smegmatis_MC2_155 IVMTTTLSKALGS--QGGAVLGPEAVRAHLIDTARSFIFDTGLAPAAVGA
Mb1542c|M.bovis_AF2122/97 KYTWQDKGSSYLPSELVAAFLWAQFEEAERITRIRLDLWNRYHESFESLE
Rv1504c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2320|M.marinum_M KYTWQDKGSSYLSSELIAAFLWAQFEDAERITRSRLDLWNYYHAGFESLE
MAB_2610|M.abscessus_ATCC_1997 YGLNSRLDN------LQAAVLRARLDWLGENNLARSILARRYVDGLADLA
MLBr_01217|M.leprae_Br4923 ARAALQILKAETWRPEAVLQHARTLAKICDLSELPQSAVVSVVLGDPEVA
MAV_3205|M.avium_104 ARAALGVLRAEPWRVGAVLRHAGVLAEVCRVREVPQSAVVSVILGDPDVA
Mflv_3628|M.gilvum_PYR-GCK AHAALQVLVEEPWRAQRVLDHATTLAQICGVADVPSSAVVSVILGEPEVA
Mvan_2789|M.vanbaalenii_PYR-1 AFAALQVLIDEPWRAQRVLDHAATLASICDVTEVPSSAVVSVILGEPEVA
MSMEG_3189|M.smegmatis_MC2_155 ASAALRVLDAEPQRARAVLDRAAELATIAGVTEAPVSAVVSVILGDPEIA
Mb1542c|M.bovis_AF2122/97 QRGLLRRPIIPQGCSHNAHMYYVLLAPSADREEVLARLTSKGIGAVFHYV
Rv1504c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2320|M.marinum_M QRGLLRRPIIPEGCSHNAHMYYVLLAPGTDRAGVLAALAKEDINAVFHYV
MAB_2610|M.abscessus_ATCC_1997 ESGLLRLPHWDTDHVWHLFTVEVTKHDRDKVTESLRAAGVATDLYYPVLT
MLBr_01217|M.leprae_Br4923 LAAAIACLDAGVRVGCFRPPTVPAGTSRLRLTAHASLDSAKLEVARRVLT
MAV_3205|M.avium_104 VAAATACLDAGVRVGCFRPPTVPAGTSRLRLTARASLDDAELEVARRVLT
Mflv_3628|M.gilvum_PYR-GCK LAAAMGCLERGVRVGCFRPPTVPAGTSRLRLTARASLSDDEMALAREVLT
Mvan_2789|M.vanbaalenii_PYR-1 FAAAAACLDRGVRVGCFRPPTVPAGTSRLRLTARASLSEDEMTLARRVLT
MSMEG_3189|M.smegmatis_MC2_155 VGAAAACLDRGVRVGCFRPPTVPAGTSRLRLAARASLTDDEMALARQVLT
Mb1542c|M.bovis_AF2122/97 PLHDSPAGRRYGRTNGNLTVTNDVASRLIRLPMWVGLQEVDQSRVVEALT
Rv1504c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2320|M.marinum_M PLHDSPAGRRYGRTSGDLTVTNDSSSRLIRLPMWVGLQEADQNRVVDALT
MAB_2610|M.abscessus_ATCC_1997 HRHRVPLVADLFEG-VRLPRTEAAHARMFQLPLYPTLTLAEQDRVIGVLH
MLBr_01217|M.leprae_Br4923 DVLGGCCVARR
MAV_3205|M.avium_104 DVLAGLG----
Mflv_3628|M.gilvum_PYR-GCK DVLSRA-----
Mvan_2789|M.vanbaalenii_PYR-1 EVLSPR-----
MSMEG_3189|M.smegmatis_MC2_155 DVLATARA---
Mb1542c|M.bovis_AF2122/97 RILTLRA----
Rv1504c|M.tuberculosis_H37Rv -----------
MMAR_2320|M.marinum_M RILTFGA----
MAB_2610|M.abscessus_ATCC_1997 DVLG-------