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PVVEASSPLAWLGEVERQREAAGLRRRLRTRSAAEPEIDLASNDYLGLSRHPQVIEAGVEALRIWGAGST GSRLVTGNTELHEELEQELATFMGTESALVFSSGYTANLGAVVALSGPGTLIVSDARTHASLIDACRLSR ARVVVTPYRDTQAVAAALAQRPEERALVLTDAVFSADGALAPLAELYGVCRRHGAVLLVDEAHGLGVRGS GGRGLVAEMNLAGRDDLVVTVTLSKALGSQGGAVLGSAAVRAHLIDAARPFIFDTGLAPAAVGSALAALR LMIDEPARIRAVLAHAAALGQWCGVPDKPESAVVPVVLGDPTVAFNAARSCLEQGVRVGCFRPPSVPEGQ SLLRLTARASLTEADMERVHEVLAGVLTLARR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2687c | - | - | 100% (383) | 8-amino-7-oxononanoate synthase |
| M. abscessus ATCC 19977 | MAB_3978c | - | 8e-10 | 30.63% (222) | glutamate-1-semialdehyde aminotransferase |
| M. abscessus ATCC 19977 | MAB_2339 | argD | 1e-08 | 26.74% (273) | acetylornithine aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1596 | bioF1 | 1e-144 | 69.41% (376) | 8-amino-7-oxononanoate synthase |
| M. gilvum PYR-GCK | Mflv_3628 | - | 1e-148 | 71.39% (374) | 8-amino-7-oxononanoate synthase |
| M. tuberculosis H37Rv | Rv1569 | bioF1 | 1e-144 | 69.41% (376) | 8-amino-7-oxononanoate synthase |
| M. leprae Br4923 | MLBr_01217 | bioF | 1e-138 | 69.09% (372) | 8-amino-7-oxononanoate synthase |
| M. marinum M | MMAR_2384 | bioF1 | 1e-141 | 69.89% (372) | 8-amino-7-oxononanoate synthase BioF1 |
| M. avium 104 | MAV_3205 | bioF | 1e-141 | 70.08% (371) | 8-amino-7-oxononanoate synthase |
| M. smegmatis MC2 155 | MSMEG_3189 | bioF | 1e-144 | 69.33% (375) | 8-amino-7-oxononanoate synthase |
| M. thermoresistible (build 8) | TH_2609 | - | 1e-08 | 64.29% (42) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1560 | bioF1 | 1e-141 | 69.62% (372) | 8-amino-7-oxononanoate synthase |
| M. vanbaalenii PYR-1 | Mvan_2789 | - | 1e-148 | 72.31% (372) | 8-amino-7-oxononanoate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01217|M.leprae_Br4923 ----MKVPIETSPLAWLEAVEQQRRGAGLRRSLRPRSAVATELDLASNDY
MAV_3205|M.avium_104 ----MKAPIEVSPLAWLDAVEQQRRAAGLRRSLRPRPPVATELDLASNDY
Mb1596|M.bovis_AF2122/97 MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDY
Rv1569|M.tuberculosis_H37Rv MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDY
MMAR_2384|M.marinum_M MGAPTQIPIETSPLAWLDAVERQRRDAGLRRSLRPRPPVGTELDLASNDY
MUL_1560|M.ulcerans_Agy99 MGAPTQIPIETSPLAWLDAVERQRRDAGLRRSLRPRPPVGTELDLASNDY
Mflv_3628|M.gilvum_PYR-GCK -----MTRAGLSPLAWLDEVETQRRAAGLRRSLRARPPVGTVLDLASNDY
Mvan_2789|M.vanbaalenii_PYR-1 -----MTRVSLSPLAWLDEVETQRRAAGLRRTVRTRPPVGAELDLASNDY
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 -----MTRAGLSPLAWLADIEQRRRAEGLRRELRVRPPVAAELDLASNDY
MAB_2687c|M.abscessus_ATCC_199 ----MPVVEASSPLAWLGEVERQREAAGLRRRLRTRSAAEPEIDLASNDY
MLBr_01217|M.leprae_Br4923 LGLSQHPDVIDGGVAALRVWGAGATGSRLVTGDTILHHELECELAEFVGA
MAV_3205|M.avium_104 LGLSQHPDVIDGGVAALRLWGAGATGSRLVTGDTELHQQFESELADYVGA
Mb1596|M.bovis_AF2122/97 LGLSRHPAVIDGGVQALRIWGAGATGSRLVTGDTKLHQQFEAELAEFVGA
Rv1569|M.tuberculosis_H37Rv LGLSRHPAVIDGGVQALRIWGAGATGSRLVTGDTKLHQQFEAELAEFVGA
MMAR_2384|M.marinum_M LGLSQHPDVIEGGVQALRIWGAGATGSRLVTGDTELHQQLEAELAEYVGA
MUL_1560|M.ulcerans_Agy99 LGLSQHPDVIEGGVQALRIWGAGATGSRLVTGDTELHQQLEAELAEYVGA
Mflv_3628|M.gilvum_PYR-GCK LGLSQHPRVIDGGVAALRTWGAGATGSRLVTGNTELHEQFEDALASFVGA
Mvan_2789|M.vanbaalenii_PYR-1 LGLSQHPRVIDGGVSALRTWGAGSTGSRLVTGNTELHEAFEDVLAAFVGA
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 LGLSQHPDVLDGGVEALRTWGGGAGGSRLVTGNTELHEAFEHQLASFLGA
MAB_2687c|M.abscessus_ATCC_199 LGLSRHPQVIEAGVEALRIWGAGSTGSRLVTGNTELHEELEQELATFMGT
MLBr_01217|M.leprae_Br4923 CVGLLFSSGYAANLGAVVGLSGPGSLIVSDAYSHASLVDACRLSRARVVV
MAV_3205|M.avium_104 ASGLLFSSGYAANLGAVVGLSGRGALVVSDAYSHASLVDACRLSRARVVV
Mb1596|M.bovis_AF2122/97 AAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDACRLSRARVVV
Rv1569|M.tuberculosis_H37Rv AAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDACRLSRARVVV
MMAR_2384|M.marinum_M AAGLLFSSGYTANLGAVVGLSGPGSLLVSDAYSHASLVDACRLSRARVVV
MUL_1560|M.ulcerans_Agy99 AAGLLFSSGYTANLGAVVGLSGPGSLLVSDAYSHASLVDACRLSRARVVV
Mflv_3628|M.gilvum_PYR-GCK DSALVFSSGYTANLGAVVALSGPGSLLVSDAYTHASLVDACRLSRARVVV
Mvan_2789|M.vanbaalenii_PYR-1 ESALVFSSGYTANLGAVVALSGPGSLLVSDANTHASLVDACRLSRARVVV
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 ESALVFSSGYTANLGALVALSGPGSLIVSDALSHASLVDACRLSRARVVV
MAB_2687c|M.abscessus_ATCC_199 ESALVFSSGYTANLGAVVALSGPGTLIVSDARTHASLIDACRLSRARVVV
MLBr_01217|M.leprae_Br4923 TPHCDVDAVDTALRSCHEERAVVVTESVFSADGVLAPVSELHDVCRRHGA
MAV_3205|M.avium_104 TPHRDVDAVLAALADRDEERAVVITESVFSTDGALAPLRELHEVCRRHRA
Mb1596|M.bovis_AF2122/97 TPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGA
Rv1569|M.tuberculosis_H37Rv TPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGA
MMAR_2384|M.marinum_M TPHRDVAAVDAALASRDEQRAMVITDSVFSADGTLAPLRELLAACRRHRA
MUL_1560|M.ulcerans_Agy99 TPHRDVAAVDAALASRDEQRAMVITDSVFSADGTLAPLRELLAACRRHRA
Mflv_3628|M.gilvum_PYR-GCK TPHNDVAAVARALATRDEERAVVVTDSVFSADGDLAPLRELHDACRRHGA
Mvan_2789|M.vanbaalenii_PYR-1 TPHNDTAAVEQALATRSEARAVVVTDSVFSADGDLAPLRALHTACRKHGA
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 SPHRDVDAVDAALAARTEERAVVVTESVFSADGDLAPLRDLHAVCRRHGA
MAB_2687c|M.abscessus_ATCC_199 TPYRDTQAVAAALAQRPEERALVLTDAVFSADGALAPLAELYGVCRRHGA
MLBr_01217|M.leprae_Br4923 LLLVDEAHGLGVRG-GGRGLVYEVGLAGAPDVVITTTMSKALGSQGGAVL
MAV_3205|M.avium_104 LLIVDEAHGLGVRG-GGRGLVFEAGLAGAPDVVMTTTLSKALGSQGGAVL
Mb1596|M.bovis_AF2122/97 LLLVDEAHGLGVRG-GGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVL
Rv1569|M.tuberculosis_H37Rv LLLVDEAHGLGVRG-GGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVL
MMAR_2384|M.marinum_M LLVIDEAHGLGVRG-GGRGLLHELGLAGAPDVVLTTTLSKALGSQGGAVL
MUL_1560|M.ulcerans_Agy99 LLVIDEAHGLGVRG-GGRGLLHELGLAGAPDVVLTTTLSKALGSQGGAVL
Mflv_3628|M.gilvum_PYR-GCK LMIVDEAHGLGVRGDRGRGLLDEVGLAGAPDVVMTTTLSKALGSQGGVVL
Mvan_2789|M.vanbaalenii_PYR-1 LLIVDEAHGLGVRGDGGRGLLDEVGLAGAPDLVMTTTLSKALGSQGGVVL
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 LLLVDEAHGLGVRGTRGQGLLHEVGLAGAPDIVMTTTLSKALGSQGGAVL
MAB_2687c|M.abscessus_ATCC_199 VLLVDEAHGLGVRGSGGRGLVAEMNLAGRDDLVVTVTLSKALGSQGGAVL
MLBr_01217|M.leprae_Br4923 GSSAVRAHLINTARPFIFDTGLAPAAVGAARAALQILKAETWRPEAVLQH
MAV_3205|M.avium_104 GPAAVRAHLIDAARTFIFDTGLAPAAVGAARAALGVLRAEPWRVGAVLRH
Mb1596|M.bovis_AF2122/97 GPTPVRAHLIDAARPFIFDTGLAPAAVGAARAALRVLQAEPWRPQAVLNH
Rv1569|M.tuberculosis_H37Rv GPTPVRAHLIDAARPFIFDTGLAPAAVGAARAALRVLQAEPWRPQAVLNH
MMAR_2384|M.marinum_M GPAAVRAHLIDAARPFIFDTGLAPAAVGAARAALGVLKAEQWRPDAVLQN
MUL_1560|M.ulcerans_Agy99 GPAAVRAHLIDAARPFIFDTGLAPGAVGAARAALGVLKAEQWRPGAVLQN
Mflv_3628|M.gilvum_PYR-GCK GPAAVRDHLIDAARPFIFDTGLAPAAVGAAHAALQVLVEEPWRAQRVLDH
Mvan_2789|M.vanbaalenii_PYR-1 GPAAVRAHLIDTARPFIFDTGLAPAAVGAAFAALQVLIDEPWRAQRVLDH
TH_2609|M.thermoresistible__bu --------------------------------------------------
MSMEG_3189|M.smegmatis_MC2_155 GPEAVRAHLIDTARSFIFDTGLAPAAVGAASAALRVLDAEPQRARAVLDR
MAB_2687c|M.abscessus_ATCC_199 GSAAVRAHLIDAARPFIFDTGLAPAAVGSALAALRLMIDEPARIRAVLAH
MLBr_01217|M.leprae_Br4923 ARTLAKICDLSELPQSAVVSVVLGDPEVALAAAIACLDAGVRVGCFRPPT
MAV_3205|M.avium_104 AGVLAEVCRVREVPQSAVVSVILGDPDVAVAAATACLDAGVRVGCFRPPT
Mb1596|M.bovis_AF2122/97 AGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPT
Rv1569|M.tuberculosis_H37Rv AGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPT
MMAR_2384|M.marinum_M ARELADICDVPETPQSAVVSVLLGDPEVALAAAAACLDAGVKVGCFRPPT
MUL_1560|M.ulcerans_Agy99 ARELADICDVPETPQSAVVSVLLGDPEVALAAAAACLDAGVKVGCFRPPT
Mflv_3628|M.gilvum_PYR-GCK ATTLAQICGVADVPSSAVVSVILGEPEVALAAAMGCLERGVRVGCFRPPT
Mvan_2789|M.vanbaalenii_PYR-1 AATLASICDVTEVPSSAVVSVILGEPEVAFAAAAACLDRGVRVGCFRPPT
TH_2609|M.thermoresistible__bu ----------------------------------------VRVGCFRPPT
MSMEG_3189|M.smegmatis_MC2_155 AAELATIAGVTEAPVSAVVSVILGDPEIAVGAAAACLDRGVRVGCFRPPT
MAB_2687c|M.abscessus_ATCC_199 AAALGQWCGVPDKPESAVVPVVLGDPTVAFNAARSCLEQGVRVGCFRPPS
*:*******:
MLBr_01217|M.leprae_Br4923 VPAGTSRLRLTAHASLDSAKLEVARRVLTDVLGGCCVARR
MAV_3205|M.avium_104 VPAGTSRLRLTARASLDDAELEVARRVLTDVLAGLG----
Mb1596|M.bovis_AF2122/97 VPAGTSRLRLTARASLNAGELELARRVLTDVL---AVARR
Rv1569|M.tuberculosis_H37Rv VPAGTSRLRLTARASLNAGELELARRVLTDVL---AVARR
MMAR_2384|M.marinum_M VPAGTSRLRLTARASLSPDEMELARRVLTDVLLGPAAARR
MUL_1560|M.ulcerans_Agy99 VPAGTSRLRLTARASLSPDEMELARRVLTDVLLGPAAARR
Mflv_3628|M.gilvum_PYR-GCK VPAGTSRLRLTARASLSDDEMALAREVLTDVLSRA-----
Mvan_2789|M.vanbaalenii_PYR-1 VPAGTSRLRLTARASLSEDEMTLARRVLTEVLSPR-----
TH_2609|M.thermoresistible__bu VPAGTSRLRLTARASLTEDELALARRVFGEVLGARP----
MSMEG_3189|M.smegmatis_MC2_155 VPAGTSRLRLAARASLTDDEMALARQVLTDVLATARA---
MAB_2687c|M.abscessus_ATCC_199 VPEGQSLLRLTARASLTEADMERVHEVLAGVLTLARR---
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