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M. bovis AF2122 / 97 Mb1542c (-)

annotation: TDP-4-oxo-6-deoxy-D-glucose transaminase
coordinates: 1690741 - 1691889
length: 382

VSDHKVPFNRPYMTGRELAYIAEAHSCGHLAGDGPFTRRSHAWLEQQTGCRKALLTPSCTAALEMMALLL
DIEEGDEVILPSYTFVSTANAFVLRGGVPVFVDIRPDTLNIDETRIVDAITPRTKAIVPVHYAGVACEMD
AIMKIATHHNLAVVEDAAQGAMASYRGRALGSIGDLGALSFHETKNVISGEGGALLVNSEDFLLRAEILR
EKGTNRSRFLRNEVDKYTWQDKGSSYLPSELVAAFLWAQFEEAERITRIRLDLWNRYHESFESLEQRGLL
RRPIIPQGCSHNAHMYYVLLAPSADREEVLARLTSKGIGAVFHYVPLHDSPAGRRYGRTNGNLTVTNDVA
SRLIRLPMWVGLQEVDQSRVVEALTRILTLRA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1542c--100% (382)TDP-4-oxo-6-deoxy-D-glucose transaminase
M. bovis AF2122 / 97Mb3436c-5e-1028.29% (205) hypothetical protein Mb3436c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv1504c-1e-112100.00% (199) hypothetical protein Rv1504c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2610-2e-2329.91% (331) putative aminotransferase
M. marinum MMMAR_2320wecE0.086.05% (380) pyridoxal phosphate-dependent enzyme, WecE
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb1542c|M.bovis_AF2122/97           ---------------------------------MSDHKVPFNRPYMTGRE
Rv1504c|M.tuberculosis_H37Rv        ---------------------------------MSDHKVPFNRPYMTGRE
MMAR_2320|M.marinum_M               ---------------------------------MVEHKIPFNRPYMTGQE
MAB_2610|M.abscessus_ATCC_1997      MSIAESANASVRTGPAPSSKTREFARAILSGTAVHPEEIPAGRAYTTLRD
                                                                     :  .::* .*.* * ::

Mb1542c|M.bovis_AF2122/97           LAYIAEAHSCGHLAGD----------------------------------
Rv1504c|M.tuberculosis_H37Rv        LAYIAEAHSCGHLAGD----------------------------------
MMAR_2320|M.marinum_M               LNYIAEAHSCGHLAGD----------------------------------
MAB_2610|M.abscessus_ATCC_1997      LATHPGLRDVTDVLIPGSAPDTVDFLPLARLVNAAELPAIRAAIDSVLPS
                                    *   .  :.  .:                                     

Mb1542c|M.bovis_AF2122/97           -----GPFTRRSHAWLEQQTGCRKALLTPSCTAALEMMALLLDIEEGDEV
Rv1504c|M.tuberculosis_H37Rv        -----GPFTRRSHAWLEQQTGCRKALLTPSCTAALEMMALLLDIEEGDEV
MMAR_2320|M.marinum_M               -----GPFTYRCHAWLEQQTGCRKALLTPSCTAALEMMALLLEIEEGDEV
MAB_2610|M.abscessus_ATCC_1997      GKFTSGPHVDAFEDEIATYLGIDHVIGASSGTDAMTAVLLALGAGPGTEV
                                         **..   .  :    *  :.: :.* * *:  : * *    * **

Mb1542c|M.bovis_AF2122/97           ILPSYTFVSTANAFVLRGGVPVFVDIRPDTLNIDETRIVDAITPRTKAIV
Rv1504c|M.tuberculosis_H37Rv        ILPSYTFVSTANAFVLRGGVPVFVDIRPDTLNIDETRIVDAITPRTKAIV
MMAR_2320|M.marinum_M               ILPSFTFVSTANAFVLRGGVPVFVDIRPDTLNVDETLIEAAITPRTRAIV
MAB_2610|M.abscessus_ATCC_1997      ILPANSFAATENAVFLTGARPVLVDTRADDHLLDPTEVEAAITSRTVAVL
                                    ***: :*.:* **..* *. **:** *.*   :* * :  ***.** *::

Mb1542c|M.bovis_AF2122/97           PVHYAGVACEMDAIMKIATHHNLAVVEDAAQGAMASYRGRALGSIGDLGA
Rv1504c|M.tuberculosis_H37Rv        PVHYAGVACEMDAIMKIATHHNLAVVEDAAQGAMASYRGRALGSIGDLGA
MMAR_2320|M.marinum_M               PVHYAGVACEMDTIMSIARRHKLAVVEDAAQGTMAYYRGRALGSIGDLGA
MAB_2610|M.abscessus_ATCC_1997      PVHLYGAFADIHALTEVTSRHGIPVVEDGCQGIGLDG----LGHHSDAAI
                                    ***  *. .::.:: .:: :* :.****..**         **  .* . 

Mb1542c|M.bovis_AF2122/97           LSFHETKNV-ISGEGGALLVNSEDFLLRAEILREKGTNRSRFLRNEVDKY
Rv1504c|M.tuberculosis_H37Rv        LSFHETKNV-ISGEGGALLVNS----------------------------
MMAR_2320|M.marinum_M               LSFHETKNV-ISGEGGALLVNSEEYIYRAEILRDKGTNRSRFLRKEVDKY
MAB_2610|M.abscessus_ATCC_1997      LSFNPYKNLGAVGKAGAVATRLPGLARRVTELLYHG------FAAGQKNV
                                    ***:  **:   *:.**: ..                             

Mb1542c|M.bovis_AF2122/97           TWQDKGSSYLPSELVAAFLWAQFEEAERITRIRLDLWNRYHESFESLEQR
Rv1504c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2320|M.marinum_M               TWQDKGSSYLSSELIAAFLWAQFEDAERITRSRLDLWNYYHAGFESLEQR
MAB_2610|M.abscessus_ATCC_1997      KAAGYGLNSRLDNLQAAVLRARLDWLGENNLARSILARRYVDGLADLAES
                                                                                      

Mb1542c|M.bovis_AF2122/97           GLLRRPIIPQGCSHNAHMYYVLLAPSADREEVLARLTSKGIGAVFHYVPL
Rv1504c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2320|M.marinum_M               GLLRRPIIPEGCSHNAHMYYVLLAPGTDRAGVLAALAKEDINAVFHYVPL
MAB_2610|M.abscessus_ATCC_1997      GLLR---LPHWDTDHVWHLFTVEVTKHDRDKVTESLRAAGVATDLYYPVL
                                                                                      

Mb1542c|M.bovis_AF2122/97           HDSPAGRRYGRTNG--NLTVTNDVASRLIRLPMWVGLQEVDQSRVVEALT
Rv1504c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_2320|M.marinum_M               HDSPAGRRYGRTSG--DLTVTNDSSSRLIRLPMWVGLQEADQNRVVDALT
MAB_2610|M.abscessus_ATCC_1997      THRHRVPLVADLFEGVRLPRTEAAHARMFQLPLYPTLTLAEQDRVIGVLH
                                                                                      

Mb1542c|M.bovis_AF2122/97           RILTLRA
Rv1504c|M.tuberculosis_H37Rv        -------
MMAR_2320|M.marinum_M               RILTFGA
MAB_2610|M.abscessus_ATCC_1997      DVLG---