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MSVTASPQAPSAAHIARIYKTHLSGGRATLGDIFGGHIETSSDGAWLTTAEGTRFLNAGGYGVALAGYRH PVVVDHIRRQLDQHPVASRMFYEPAAAEAAAALAAVTPKGLDRIHFACSGAEATEAAMKLARLNGCRRFI SMTGGYHGKTLGALSLTAREVFQAPFRPLLPGVSHVPYGDLAALRTELAMSTARACVIVEPVQGEAGVII PPDGYLAGLRAVCDEYGALLVADEIQTGLGRLGQWWGVDRERVIPDILLSGKMLGGGVMPVSAAITTTEC FRQLDRDPYLHTSTFSTSPLGMAAVSGALRVIAEERLVERAAELGQILLDRISSASAQWFGPDQVQVRGQ GLLIGIEFTDASIVGDLLIELISNNIIVNHSLNSDHVLRLTPPAVITDDDVEFLVQGYLNAIEQVAIRAK AALPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2279 | - | - | 100% (425) | ornithine aminotransferase |
| M. abscessus ATCC 19977 | MAB_2339 | argD | 9e-61 | 38.06% (381) | acetylornithine aminotransferase |
| M. abscessus ATCC 19977 | MAB_3841 | - | 4e-51 | 31.92% (401) | ornithine aminotransferase RocD1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1683 | argD | 1e-57 | 36.98% (384) | acetylornithine aminotransferase |
| M. gilvum PYR-GCK | Mflv_3527 | argD | 3e-60 | 38.16% (380) | acetylornithine aminotransferase |
| M. tuberculosis H37Rv | Rv1655 | argD | 1e-57 | 36.98% (384) | acetylornithine aminotransferase |
| M. leprae Br4923 | MLBr_01409 | argD | 3e-57 | 37.06% (367) | acetylornithine aminotransferase |
| M. marinum M | MMAR_2465 | argD | 6e-59 | 37.33% (367) | acetylornithine aminotransferase ArgD |
| M. avium 104 | MAV_3115 | argD | 5e-57 | 35.16% (401) | acetylornithine aminotransferase |
| M. smegmatis MC2 155 | MSMEG_3773 | argD | 1e-59 | 38.15% (367) | acetylornithine aminotransferase |
| M. thermoresistible (build 8) | TH_3529 | - | 4e-57 | 37.24% (384) | PUTATIVE aminotransferase |
| M. ulcerans Agy99 | MUL_1647 | argD | 7e-59 | 36.53% (386) | acetylornithine aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_3146 | - | 4e-59 | 38.10% (378) | aminotransferase class-III |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1683|M.bovis_AF2122/97 --MTGASTTTATMRQRWQAVMMNNY-GTPPIA--------LASGDGAVVT
Rv1655|M.tuberculosis_H37Rv --MTGASTTTATMRQRWQAVMMNNY-GTPPIA--------LASGDGAVVT
MLBr_01409|M.leprae_Br4923 --MTPTQTNTATMQQRWETVMMNNY-GTPPIV--------LASGNGAVVT
MAV_3115|M.avium_104 -----MVTNTDALRRRWEAVMMHNY-GTPPVA--------LASGEGAVVT
MMAR_2465|M.marinum_M ------MTHTEDTRARWEAVMMNNY-GTPPVA--------LASGEGAVVT
MUL_1647|M.ulcerans_Agy99 ------MTHTEDTRARWEAVMMNNY-GTPPVA--------LASGEGAVVT
Mflv_3527|M.gilvum_PYR-GCK ----MTGEHRPGLLDRWSAVMMNNY-GTPPLA--------LASGQGAVVT
MSMEG_3773|M.smegmatis_MC2_155 ----------MTLQSRWEAVMMNNY-GTPPLS--------LVSGEGAVVT
TH_3529|M.thermoresistible__bu ---VSGSKGRHTLLDRWQGVMMNNY-GTPPLA--------LVSGDGAVVT
Mvan_3146|M.vanbaalenii_PYR-1 MYPTMSGVEIESYRDRFVRHLSQTVPGRKEFV--------VAEARGCTVT
MAB_2279|M.abscessus_ATCC_1997 --MSVTASPQAPSAAHIARIYKTHLSGGRATLGDIFGGHIETSSDGAWLT
: * ... *. :*
Mb1683|M.bovis_AF2122/97 DVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHT--SNLYATEP
Rv1655|M.tuberculosis_H37Rv DVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHT--SNLYATEP
MLBr_01409|M.leprae_Br4923 DVDSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLGHT--SNLYATEP
MAV_3115|M.avium_104 DVDGNTYLDLLGGIAVNVLGHRHPAIIEAVTKQLSTLGHT--SNLYATEP
MMAR_2465|M.marinum_M DVDGKNYVDLLGGIAVNILGHRHPAVIEAVTQQMSTLGHT--SNLYATEP
MUL_1647|M.ulcerans_Agy99 DVDGKNYVDLLGGIAVNILGHRHPAVIEAVTQQMSTLGHT--SNLYATEP
Mflv_3527|M.gilvum_PYR-GCK DADGKSYIDLLGGIAVNVLGHRHPAVIEAVTRQMNTLGHT--SNLYATEP
MSMEG_3773|M.smegmatis_MC2_155 DADGREYLDLLGGIAVNLLGHRHPAVIEAVTTQLDTLGHT--SNLYATEP
TH_3529|M.thermoresistible__bu DADGKSYLDLLGGIAVNILGHRHPAVIEAVTRQLNTLGHT--SNLYATEP
Mvan_3146|M.vanbaalenii_PYR-1 TADGRSYLDMTSGIGVANVGHCHPRVVEAIQAQAARYAHVNVYGRFVVPE
MAB_2279|M.abscessus_ATCC_1997 TAEGTRFLN-AGGYGVALAGYRHPVVVDHIRRQLDQHPVA--SRMFYEPA
.:. ::: .* .* *: ** ::: : * . :
Mb1683|M.bovis_AF2122/97 GIALAEELVALLGADQR--------------TRVFFCNSGAEANEAAFKL
Rv1655|M.tuberculosis_H37Rv GIALAEELVALLGADQR--------------TRVFFCNSGAEANEAAFKL
MLBr_01409|M.leprae_Br4923 SITLAEELVALLGADTQ--------------TRVFFCNSGTEANELAFKL
MAV_3115|M.avium_104 SLALAEELVALLGAGHEPAGHESGGTESAGTARVFFCNSGTEANEVAFKL
MMAR_2465|M.marinum_M TIALAEELVTLLGAEAP--------------ARVFFCNSGTEANEAAFKL
MUL_1647|M.ulcerans_Agy99 TNALAEELVTLLGAEAP--------------ARVFFCNSGTEANEAAFKL
Mflv_3527|M.gilvum_PYR-GCK GVALAEALVDLLGVPAK----------------VFFCNSGTEANEVAFKI
MSMEG_3773|M.smegmatis_MC2_155 GIALAEALVGQLGTQAR----------------VFFCNSGTEANEVAFKI
TH_3529|M.thermoresistible__bu GVALAEALVGHLGAPAR----------------VFFCNSGAEANEVAFKI
Mvan_3146|M.vanbaalenii_PYR-1 QVELVERLTGAAGAGFD---------------MAYLTSSGAESTECAMKL
MAB_2279|M.abscessus_ATCC_1997 AAEAAAALAAVTPKGLD---------------RIHFACSGAEATEAAMKL
. *. .: **:*:.* *:*:
Mb1683|M.bovis_AF2122/97 SR-LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYG
Rv1655|M.tuberculosis_H37Rv SR-LTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYG
MLBr_01409|M.leprae_Br4923 SR-LTGRTKLVAAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYG
MAV_3115|M.avium_104 SR-LTGRTKLVAAQEAFHGRTMGSLALTGQPSKQAPFAPLPGDVTHVPYG
MMAR_2465|M.marinum_M SR-LTGRTKLVAAQEGFHGRTMGSLALTGQPAKQAPFEPLPGYVTHVPYG
MUL_1647|M.ulcerans_Agy99 SR-LTGRTKLVAAQEGFHGRTMGSLALTGQPAKQAPFEPLPGYVTHVPYG
Mflv_3527|M.gilvum_PYR-GCK TR-LTGRTKLVAAQGAFHGRTMGSLALTGQPAKQAPFEPLPGDVTHVPYG
MSMEG_3773|M.smegmatis_MC2_155 TR-LTGKTKIVAAEGAFHGRTMGSLALTGQPSKQAPFEPLPGNVMHVPYG
TH_3529|M.thermoresistible__bu SR-LTGRTKVVAAEGGFHGRTMGALALTGQPSKREPFEPLPGDVIHVPYG
Mvan_3146|M.vanbaalenii_PYR-1 ARKHTGRPKFVAFERAYHGRTLGALSVSWREEWRAPFEPLLDEVMFVPYD
MAB_2279|M.abscessus_ATCC_1997 AR-LNGCRRFISMTGGYHGKTLGALSLTAREVFQAPFRPLLPGVSHVPYG
:* .* :.:: .:**:*:*:*::: : : .* ** * .* *.
Mb1683|M.bovis_AF2122/97 DVDAL--AAAVDDHTAAVFLEPIMGESGVVVPPAGYLAAARDITARRGAL
Rv1655|M.tuberculosis_H37Rv DVDAL--AAAVDDHTAAVFLEPIMGESGVVVPPAGYLAAARDITARRGAL
MLBr_01409|M.leprae_Br4923 QVDAL--AAAVDNDTAAVFLEPIMGESGVIVPPEGYLAAARDITTRHGAL
MAV_3115|M.avium_104 DTEAL--AAAVDDGTAAVFLEPIMGESGVVVPPEGYLAAARDITARHGAL
MMAR_2465|M.marinum_M DIDAL--AAAVDDETAAVFLEPIMGESGVVVPPEGYLLAAREITARHGAL
MUL_1647|M.ulcerans_Agy99 DIDAL--AAAVDDETAAVFLEPIMGESGVVVPPEGYLLAAREITARHGAL
Mflv_3527|M.gilvum_PYR-GCK DVDAL--RAVVDSETAAVFLEPIMGEGGVVVPPAGYLVAAREITAEHGAL
MSMEG_3773|M.smegmatis_MC2_155 DVAAL--EAAVDDQTAAVFLEPIMGEGGVVVPPAGYLVAAREITSKHGAL
TH_3529|M.thermoresistible__bu DAGAL--ERAVDDTTAAVFLEPIMGEGGVVVPPAGYLAAAREVTARHGAL
Mvan_3146|M.vanbaalenii_PYR-1 SLTAA--AAAVDDRTAAVIVEPIQGEGGIRVPSDDFLPGLRELCDATGAL
MAB_2279|M.abscessus_ATCC_1997 DLAALRTELAMSTARACVIVEPVQGEAGVIIPPDGYLAGLRAVCDEYGAL
. * .:. *.*::**: **.*: :*. .:* . * : ***
Mb1683|M.bovis_AF2122/97 LVLDEVQTGMGRTGAFFAHQHDGITPDVVTLAKGLGGG-LPIGACLAVGP
Rv1655|M.tuberculosis_H37Rv LVLDEVQTGMGRTGAFFAHQHDGITPDVVTLAKGLGGG-LPIGACLAVGP
MLBr_01409|M.leprae_Br4923 LVIDEVQTGIGRTGAFFAHQHDSITPDVVTLAKGLGGG-LPIGAFLATGP
MAV_3115|M.avium_104 LVLDEVQTGMGRTGTFFAHQHDGITPDVVTLAKGLGGG-LPIGACLAVGP
MMAR_2465|M.marinum_M LVLDEVQTGIGRTGAFYAHQHDGITPDVVTLAKGLGGG-LPIGACLAIGP
MUL_1647|M.ulcerans_Agy99 LVLDEVQTGIGRTGAFYAHQHDGITPDVVTLAKGLGGG-LPIGACLAIGP
Mflv_3527|M.gilvum_PYR-GCK LILDEVQTGVGRTGAFFAHRHDGITPDVVTLAKGLGGG-LPIGACLAIGD
MSMEG_3773|M.smegmatis_MC2_155 LVLDEVQTGVGRTGAFFAHQHDGIVPDVVTMAKGLGGG-LPIGACLAVGA
TH_3529|M.thermoresistible__bu LVLDEVQTGIGRTGTFFAHQHDGITPDVVTLAKGLGGG-LPIGACLAVGP
Mvan_3146|M.vanbaalenii_PYR-1 LIVDEVQGGMGRSGRWFAHQHTDVRPDIITMAKAVGGG-LPLGAVLASAE
MAB_2279|M.abscessus_ATCC_1997 LVADEIQTGLGRLGQWWGVDRERVIPDILLSGKMLGGGVMPVSAAITTTE
*: **:* *:** * ::. : : **:: .* :*** :*:.* ::
Mb1683|M.bovis_AF2122/97 -AAELLTPGL-HGSTFGGNPVCAAAALAVLRVLASDGLVRRAEVLGKSLR
Rv1655|M.tuberculosis_H37Rv -AAELLTPGL-HGSTFGGNPVCAAAALAVLRVLASDGLVRRAEVLGKSLR
MLBr_01409|M.leprae_Br4923 -AAELLTLGL-HGSTFGGNPVCTAAALAVLRVLATQGLVRRAEVLGDSMR
MAV_3115|M.avium_104 -AADLLTPGL-HGSTFGGNPVCAAAALAVLRVLASENLVRHAEVLGKSLH
MMAR_2465|M.marinum_M -AAELLTPGL-HGSTFGGNPVCAAAALAVLRVVASEGLVRRAETLGKTFK
MUL_1647|M.ulcerans_Agy99 -AAELLTPGL-HGSTFGGNPVCAAAALAVLRVVASEGLVCRAETLGKTFK
Mflv_3527|M.gilvum_PYR-GCK -TAELLTPGL-HGSTFGGNPVCTAAALAVLKVLADDGLVERADILGKTIA
MSMEG_3773|M.smegmatis_MC2_155 -TGDLLTPGL-HGSTFGGNPVCTAAGLAVLKTLAAEDLVARAGVLGKTLS
TH_3529|M.thermoresistible__bu -AGDLLTPGM-HGSTFGGNPVCTAAAVAVLGALAEGDLINRADVLGKKLS
Mvan_3146|M.vanbaalenii_PYR-1 LFATFVDPPLSHLTTMGGNPVACAAGIAAFDVIADG-LLDRVVEAGEYLR
MAB_2279|M.abscessus_ATCC_1997 CFRQLDRDPYLHTSTFSTSPLGMAAVSGALRVIAEERLVERAAELGQILL
: * :*:. .*: ** ..: .:* *: :. *. :
Mb1683|M.bovis_AF2122/97 HGIEALG----HPLIDHVRGRGLLLGIALTAPHAKDAEATARDAG-YLVN
Rv1655|M.tuberculosis_H37Rv HGIEALG----HPLIDHVRGRGLLLGIALTAPHAKDAEATARDAG-YLVN
MLBr_01409|M.leprae_Br4923 IGIESLS----HPLIDQVRGRGLLLGIVLTAPRAKDIEKAARDAG-FLVN
MAV_3115|M.avium_104 QGIEGLG----HPLVDHVRGRGLLCGVVLTAPRAKDAEAAAREAG-FLVN
MMAR_2465|M.marinum_M QGVESLS----HPLIDHVRGRGLLLGIVLAGPHAKAAEVAAREAG-YLVN
MUL_1647|M.ulcerans_Agy99 QGVESLS----HPLIDHVRGRGLLLGIVLAGPHAKAAEVAAREVG-YLVN
Mflv_3527|M.gilvum_PYR-GCK HGIEALN----HPLVDHVRGLGLLRGIVLTADAAKSVEAEARDAG-FLVN
MSMEG_3773|M.smegmatis_MC2_155 HGIEELG----HPLVDKVRGKGLLQGIVLTVPSAKAVETAARDAG-FLVN
TH_3529|M.thermoresistible__bu HGIEELR----HPLVDHVRGRGLLCGVVLNAPQAKAAEAAARDAG-FLVN
Mvan_3146|M.vanbaalenii_PYR-1 TGLAALCD-EFAGLLVDVRGRGLWCAIELSVD-ANPVVARMQQLG-VLVG
MAB_2279|M.abscessus_ATCC_1997 DRISSASAQWFGPDQVQVRGQGLLIGIEFTDASIVGDLLIELISNNIIVN
: .*** ** .: : . :*.
Mb1683|M.bovis_AF2122/97 AAAP--DVIRLAPPLIIAEAQLDGFVAALPAILDRAVGAP------
Rv1655|M.tuberculosis_H37Rv AAAP--DVIRLAPPLIIAEAQLDGFVAALPAILDRAVGAP------
MLBr_01409|M.leprae_Br4923 ATAP--EVIRLAPPLIITESQIDSFITALPGILDASIAELGKKA--
MAV_3115|M.avium_104 AAAP--GVIRLAPPLIVTEAQIDGFIAALPGILDRAAA--------
MMAR_2465|M.marinum_M GAAP--NVVRLAPPLVITEPQLEGFVAALPGILDTAGASA------
MUL_1647|M.ulcerans_Agy99 GAAP--NVVRLAPPLVITEPQLEGFVAALPGILDNAGASA------
Mflv_3527|M.gilvum_PYR-GCK AAAA--DVIRLAPPLVITDAEVESFLAALPRILDKAAQS-------
MSMEG_3773|M.smegmatis_MC2_155 AAAP--EVVRLAPPLIITEGQIEAFITALPAVLDTAAEDS------
TH_3529|M.thermoresistible__bu AAAP--EVIRLAPPLIITETQIDEFLAALPGVLDTAKEAS------
Mvan_3146|M.vanbaalenii_PYR-1 SVLNQSGTVRIMPPLVISDAEIDTFVGVLRTVLGEVAS--------
MAB_2279|M.abscessus_ATCC_1997 HSLNSDHVLRLTPPAVITDDDVEFLVQGYLNAIEQVAIRAKAALPG
.:*: ** :::: ::: :: :