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LRREASALLAYVADHPRIAPNRIAGMIFRTRVARRYRALATVENHDQLVAALRTVVAGTEHPLVVRNSEP ATARRHGFVFPGQGGQRPGMGRLFYDAFPSFRAEVERCADLFDKQFGRSPLSYLLDDQLPTNDSATVVQP ALFTQMVGLAALWRTVGVTPRAVVGHSQGEIAGAYVSGVMSLDDAVTVVGTRAGIADEFPADDYAMAVIA TDRDTCEELLARNSGWAELSVINSPSMVGISGQRETVHQIVEHLIEDGVFARVIPVRYPAHTSMIASIGA QIRHALTENLDAGEFTVSEIDCIGATLGTAISPEMPVDQYWFWNLRNAVRFDRAVATAAAAHVDTFVELA EHPTLQLALRENLAALGSERTACVVGTSHRNATDLGEFTANLAKIAVHDLDYNWDALRTEAPDRVSLPLR DFPNVQNNDIPLWLSYRADTSGVAVPKQPIVTPEAERRVEMGNDSRAYPRLLREAWAKVTRRSMMPPRSY AFIDGTGDAGALVEALRDSAPNFGSSARIVTGTDESGIGDADTVVIVLPSPALLDDHEAADAVARFFGNR TWWPRLSSTVTGCWLVTVGGEQAIADDGPAHPVHAAIAAGFRCMGTEHPGIAFRHLDLTSDIASPDKADN ILAALQSAGESELALRADGMYAKRVLDIDQDGDESSRVVAPAHVVITGGTGKLGQEFCEHYARMGTRQIT LISRSGETDAVTGRLDAIRRSTGAKVRALPCDVTDTAAVTALADQLRDTPADLIVHAAVDYSDTPLSEVT TNKFQDALRAKVIGISNVLDTVPRTDSCRVMLCSSLAATIGGKGQLMYAAGNRMLDVLASTRRASGLDCT SIQWGQWTVHLDLGDAGIAKLAAAGVHPMRPADALAVGMGHHHGNTLVGAFDLTQARAMLGVFGYGPLLS ELEDNGGPVAPAETTRPAPVVSENRSGHLVQLLAEVIGADHADSIDTAMPMVAMGLDSLQALEFRRRVQA ELDFELPVQDLLGGASVDHVIDALTAQSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2119c | - | - | 100% (1010) | putative polyketide synthase MbtD |
| M. abscessus ATCC 19977 | MAB_3148c | - | 1e-34 | 31.20% (359) | polyketide synthase Pks5 |
| M. abscessus ATCC 19977 | MAB_0939 | - | 3e-31 | 27.48% (535) | polyketide synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2402c | mbtD | 1e-121 | 31.38% (1023) | polyketide synthetase MBTD (polyketide synthase) |
| M. gilvum PYR-GCK | Mflv_2695 | - | 1e-128 | 32.42% (1018) | acyl transferase region |
| M. tuberculosis H37Rv | Rv2381c | mbtD | 1e-121 | 31.38% (1023) | polyketide synthetase MBTD (polyketide synthase) |
| M. leprae Br4923 | MLBr_02354 | - | 8e-35 | 30.61% (379) | polyketide synthase |
| M. marinum M | MMAR_3695 | mbtD | 0.0 | 54.17% (1008) | polyketide synthase MbtD |
| M. avium 104 | MAV_2012 | - | 1e-120 | 31.89% (1019) | MbtD protein |
| M. smegmatis MC2 155 | MSMEG_4512 | - | 1e-119 | 32.20% (1025) | polyketide synthetase mbtd |
| M. thermoresistible (build 8) | TH_3022 | - | 1e-101 | 35.36% (758) | PUTATIVE acyl transferase domain protein |
| M. ulcerans Agy99 | MUL_3638 | mbtD | 0.0 | 53.47% (1008) | polyketide synthase MbtD |
| M. vanbaalenii PYR-1 | Mvan_3846 | - | 1e-125 | 33.30% (1021) | acyl transferase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 MTSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGN
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 VTGPDSFWQLLVDGGDAISEVPPDRWDADAFYDPDPSASGRMTTKWGGFV
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 PDVDAFDAEFFGITPREAVAMDPQHRMLLEVAWESLEHAGIAPDSLSGTR
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 TAVMMGLSSWDYTIVNIERRADIDAYLSTGTPHCAAVGRISYLLGLRGPA
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 MAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSPFTAIALSKWS
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 ALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSA
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 TNQDGRSNGMTAPNALAQRDVITTALRLADITPDSVNYVETHGTGTVLGD
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 PIEFESLAATYGRGESSCALGSVKTNIGHLEAAAGVAGFIKTVLALQHAY
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 IPRNVHFTQWNPAIDASTTRLFVPTESAPWPAIPGPRRGAVSSFGLSGTN
MMAR_3695|M.marinum_M ------------MSAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAA
MUL_3638|M.ulcerans_Agy99 ------------MSAAAYRLPDGTIPVLLSADTPELLDSEATALRDHVAA
MAB_2119c|M.abscessus_ATCC_199 -----------------------------------MLRREASALLAYVAD
Mb2402c|M.bovis_AF2122/97 --------------MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLER
Rv2381c|M.tuberculosis_H37Rv --------------MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLER
TH_3022|M.thermoresistible__bu ----------MTPITRANSWPDGRIPVLLSAHAEDLLRADARALLDYLDR
MSMEG_4512|M.smegmatis_MC2_155 -------------MMTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDG
Mvan_3846|M.vanbaalenii_PYR-1 --------------MSAGRLPDGRVAVPLSAHHEALVSATARDILGHLQ-
Mflv_2695|M.gilvum_PYR-GCK ------------------MLPDGRIPVLLSAHAEELIGEDARRLLGFLD-
MAV_2012|M.avium_104 -------------MMPTHGLPDGRIPVLLSSHDPELIRRDAAAILEYLDR
MLBr_02354|M.leprae_Br4923 AHVVIEQAPDTTVPISAAVGRQYVSALVVSGKTVTRVASAAAVLADWMSG
: * : :
MMAR_3695|M.marinum_M H--PDLTPGPISAMLFRTRAARRHRALAMVRTRAELIDALQAMIDRYEHP
MUL_3638|M.ulcerans_Agy99 H--PDLTPGPISAMLFRTRAARRHRALAMVRTRAELIDALQAMIDRYEHP
MAB_2119c|M.abscessus_ATCC_199 H--PRIAPNRIAGMIFRTRVARRYRALATVENHDQLVAALRTVVAGTEHP
Mb2402c|M.bovis_AF2122/97 F--PATTVTEVARQLRKTRRVRRHRAVLRAADRLELAEGLRALAAGREHP
Rv2381c|M.tuberculosis_H37Rv F--PATTVTEVARQLRKTRRVRRHRAVLRAADRLELAEGLRALAAGREHP
TH_3022|M.thermoresistible__bu E--PAAAVXXXX------------RAVIRAADRTELADGLRAVADGAEHR
MSMEG_4512|M.smegmatis_MC2_155 R--TDTAPSDVAYTLLRTRRLRRHRAVIRAGGLDELTAGLRALADGDDHP
Mvan_3846|M.vanbaalenii_PYR-1 R--NPSEPGQVAAQLVRTRRLRRHRAIVRAGDRDELAAGLQAVADDRDHP
Mflv_2695|M.gilvum_PYR-GCK ---SAPEVDAVAATLLRVRRRNRHRAVVRAADRSELADALSALAAGQEHP
MAV_2012|M.avium_104 IGESTEATGAVAATLLRLRRVRRHRALLRAADRAELAAGLAAIARGEEHA
MLBr_02354|M.leprae_Br4923 PG-AAAPLADVAYTLNQHRVRHPKLATVIARDHADAVAGLRALAAGQPRV
* . : .* :: :
MMAR_3695|M.marinum_M ALIRTDPA--AIRRRIGYVFPGQGGQRPGMGQLFYESVPAFRAEVDRCAQ
MUL_3638|M.ulcerans_Agy99 ALIRTDPA--AIRRRIGYVFPGQGGQRPGMGQLFYESVPAFRAEVDRCAQ
MAB_2119c|M.abscessus_ATCC_199 LVVRNSEP--ATARRHGFVFPGQGGQRPGMGRLFYDAFPSFRAEVERCAD
Mb2402c|M.bovis_AF2122/97 LIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYRELPTYRTATDTCAA
Rv2381c|M.tuberculosis_H37Rv LIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYRELPTYRTATDTCAA
TH_3022|M.thermoresistible__bu LVARSDH---STAPRLAFVFPGQGSQWPGMGAAAYRQFAEYRAGVDACAA
MSMEG_4512|M.smegmatis_MC2_155 LVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR-LDDYRAEVDRCAA
Mvan_3846|M.vanbaalenii_PYR-1 LVARSAG-RAGAR--TAFVFPGQGSQWPGMGGEAYRLLPVYRAEADRLTE
Mflv_2695|M.gilvum_PYR-GCK LVSRSAEP---DAHRRAFVYPGQGNQWPAMGAEAYRTLRDYRQAADVCAA
MAV_2012|M.avium_104 LITRSAR---TTPPRIAFVFPGQGNQWQAMGADAYRRLPAYREAADRCAQ
MLBr_02354|M.leprae_Br4923 GVVGCDQH--AAGPGRVFVYSGQGSQWAGMGRQLLVDEPAFAKAVAELEP
: :*:.***.: .** : .
MMAR_3695|M.marinum_M AFEAQSCGSPRNYLLDKNFQ----DDGSAGIVQPALFTQMAALAAMWRSF
MUL_3638|M.ulcerans_Agy99 AFEAQACGSPRNYLLDKNFQ----DDGSAGIVQPALFTQMAALAAMWRSF
MAB_2119c|M.abscessus_ATCC_199 LFDKQFGRSPLSYLLDDQLP----TNDSATVVQPALFTQMVGLAALWRTV
Mb2402c|M.bovis_AF2122/97 AFAAAGVDSPLPYLIAPPGT-DERQAFCEIEIEGAQFVHAVALAEVWRSC
Rv2381c|M.tuberculosis_H37Rv AFAAAGVDSPLPYLIAPPGT-DERQAFCEIEIEGAQFVHAVALAEVWRSC
TH_3022|M.thermoresistible__bu AFTAAGAPAPLRYLTTP----DDPESFCETEVEGAQFTHAVALARMWRHH
MSMEG_4512|M.smegmatis_MC2_155 AFEAAGAASPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSH
Mvan_3846|M.vanbaalenii_PYR-1 AFLAAGLTSPLPFLTADTDG----EPVSQYDLQAAQFVHSVALAAVWRSC
Mflv_2695|M.gilvum_PYR-GCK AFTAAGAPSPLRYLTDAAAV-----TGSQVEAQAAQFTHAVALTAVWRAH
MAV_2012|M.avium_104 AFVAAGFPSPLPYLVSPDEQ-----SWTRPEIQGAQFTHAVALAEAWRCF
MLBr_02354|M.leprae_Br4923 TFVAQVGFSLEHTLAYGDEV------VGIERIQPVLVGIQLALTELWRSY
* : * : . . .*: **
MMAR_3695|M.marinum_M GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRAHAADEFAAADYAM
MUL_3638|M.ulcerans_Agy99 DIPPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRAHAADEFAAADYAM
MAB_2119c|M.abscessus_ATCC_199 GVTPRAVVGHSQGEIAGAYVSGVMSLDDAVTVVGTRAGIADEFPADDYAM
Mb2402c|M.bovis_AF2122/97 GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGR-YAV
Rv2381c|M.tuberculosis_H37Rv GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGR-YAV
TH_3022|M.thermoresistible__bu GVLPDITVGHSLGEVGAAYIAGAITLADAVSVVIARAGVVDRLPGR-YAV
MSMEG_4512|M.smegmatis_MC2_155 GVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGP-YRV
Mvan_3846|M.vanbaalenii_PYR-1 GIVPDLTVGHSLGEVAAAYVAETVTLVDAVTVLAARAAAIEAIPGD-NGV
Mflv_2695|M.gilvum_PYR-GCK GVAPDMTVGHSLGEVAAAHVAGAITLAEAAAVVIARATVLEGLADG-YRM
MAV_2012|M.avium_104 GVLPEMAIGHSLGEVAAAYVAEAISLPDAVALVVARATVVDRLTGR-YAM
MLBr_02354|M.leprae_Br4923 GVTPDAVIGHSMGEVSAAVVAGALTPEQGLRVIATRSRLMARLSGQ-GAM
.: * .:*** **:..* :: :: :. :: *: :. :
MMAR_3695|M.marinum_M AIVAADRETCEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTE
MUL_3638|M.ulcerans_Agy99 AIVAADREACEDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTE
MAB_2119c|M.abscessus_ATCC_199 AVIATDRDTCEELLARNSGWAELSVINSPSMVGISGQRETVHQIVEHLIE
Mb2402c|M.bovis_AF2122/97 AALGIGEQDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRS
Rv2381c|M.tuberculosis_H37Rv AALGIGEQDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRS
TH_3022|M.thermoresistible__bu AVLGVDADAARDVIASTPGWLELSVVNAPSSVAVSGDRDAVSAAVARVRE
MSMEG_4512|M.smegmatis_MC2_155 AVLGITPEQAAEVIAETPGWLELSVVNSPSSVAVSGETGAVAAAVRTVAA
Mvan_3846|M.vanbaalenii_PYR-1 AVLGVDATEAAELIAATGGWLELSAVNAQNSVAVSGERSAVAAIAAAARA
Mflv_2695|M.gilvum_PYR-GCK AVLGLTPEDAQSLIESVPGWLELAVVNAASSVGVSGERDAVDALLAQASS
MAV_2012|M.avium_104 AVLGAGAADAESLLATTPGWVEVSAVNGPASTVVAGDHDAVAAAVRLAQQ
MLBr_02354|M.leprae_Br4923 ALLELDADAAEALIADYP-EVTLAVYASPRQSVIAGLPESVDAVISVVAE
* : . :: ::. . ::* :*
MMAR_3695|M.marinum_M GGTFARVIRVRYPAHTSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGAT
MUL_3638|M.ulcerans_Agy99 GGTFARVIRVRYPAHTSLIHDGADKLRAAIQDQLQHPSFVDTDIDCLGAT
MAB_2119c|M.abscessus_ATCC_199 DGVFARVIPVRYPAHTSMIASIGAQIRHALTENLDAGEFTVSEIDCIGAT
Mb2402c|M.bovis_AF2122/97 SGHFARGITVGFPVHTSVLES----LRDELCEQLPDSEFMEAPVQFIGGT
Rv2381c|M.tuberculosis_H37Rv SGHFARGITVGFPVHTSVLES----LRDELCEQLPDSEFMEAPVQFIGGT
TH_3022|M.thermoresistible__bu QGRFAREITVGFPVHTSILEP----LRDDLLRNLPQAEFADSPVQFIGAA
MSMEG_4512|M.smegmatis_MC2_155 RGAFAKEIEMWFPAHTTALDG----VRADLDALLPAGRFAETPVQFIGSA
Mvan_3846|M.vanbaalenii_PYR-1 RGRFAKELAMSFPAHTTAMET----QREQLVRRLPTSVFADSPVQFVGSA
Mflv_2695|M.gilvum_PYR-GCK RGVFARSVTMAFPAHTSLLDG----LRADFVRLLAPARFQQTAIPFLGSA
MAV_2012|M.avium_104 REIFAHQLFVDYPGHTSALRP----LRAALAELTPQSAFRDSPIRFIGST
MLBr_02354|M.leprae_Br4923 QNRLARRVDVEVASHHSIIDPILPELRNALADLVPQTPIIP------IIT
:*: : : . * : : * : : :
MMAR_3695|M.marinum_M LGAPITSELPVGDYWFWNLRNIVRFDKAIAAAVQ------RDVETFVELA
MUL_3638|M.ulcerans_Agy99 LGAPITSELPVGDYCFWNLRNIVRFDKAIAAAVQ------RDVETFVELA
MAB_2119c|M.abscessus_ATCC_199 LGTAISPEMPVDQYWFWNLRNAVRFDRAVATAAA------AHVDTFVELA
Mb2402c|M.bovis_AF2122/97 TGDVVAPGTTFGDYWYANLRHTVRFDRAVESAIR------CGARAFIEIS
Rv2381c|M.tuberculosis_H37Rv TGDVVAPGTTFGDYWYANLRHTVRFDRAVESAIR------CGARAFIEIS
TH_3022|M.thermoresistible__bu TGDVVPAGTGFGPYWYGNLRHLVRFDRAFQTALR------CGARTFVELS
MSMEG_4512|M.smegmatis_MC2_155 TADVVTTGTDFADYWYTNLRTTVRFDQAVARAAR------RGARIFVELS
Mvan_3846|M.vanbaalenii_PYR-1 TGQLVRAGTEFGAYWYANLRNTIRFDQAVQTAIG------LGAGVYVELS
Mflv_2695|M.gilvum_PYR-GCK TGEAVPPETDFADYWFANLRNTVRFDRAAAAAVR------AGANLFVEMS
MAV_2012|M.avium_104 RGAEVAATTDYASYWYENLCSTVRFDLAVQCARS------CGADAFVELS
MLBr_02354|M.leprae_Br4923 TTHEHTQAVMDADYWAANLRNPVRFHQAIAQAVSGVGGFNRTCHSFIEIS
* ** :**. * * ::*::
MMAR_3695|M.marinum_M EHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAV
MUL_3638|M.ulcerans_Agy99 EHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLAQLAV
MAB_2119c|M.abscessus_ATCC_199 EHPTLQLALRENLAALGSE---RTACVVGTSHRNATDLGEFTANLAKIAV
Mb2402c|M.bovis_AF2122/97 AHPALLFAIGQNCEGAANLP-DGPAVLVGSARRGERFVDALSANIVSAAV
Rv2381c|M.tuberculosis_H37Rv AHPALLFAIGQNCEGAANLP-DGPAVLVGSARRGERFVDALSANIVSAAV
TH_3022|M.thermoresistible__bu AHPSLLFAMSELLG-------DTPATLLGSTRRDEPIAETFTANLAAAAV
MSMEG_4512|M.smegmatis_MC2_155 AHPALLFNMGELLEST------RGVVLVGSGRRDEPLPERLADNVITVAL
Mvan_3846|M.vanbaalenii_PYR-1 AHPSLLFAVEDGIERVG----AAAAVLVGSGHRDESVPDRLSANIVTAAA
Mflv_2695|M.gilvum_PYR-GCK AHPALLFSLGQSAG---------DALTVGSGRRDAPLVETLSAGIATVAA
MAV_2012|M.avium_104 AHPSLLYPLSGIID-------DESAVIVGSGHRDRPITESLSASMAAVAT
MLBr_02354|M.leprae_Br4923 PHPVLTHAITDTVGGS------GGHVVTSAMNRDLDQTLFFHAQLATVGV
** * : .: .* : : .
MMAR_3695|M.marinum_M HDLNYPWECLRAEPDGAQA-------------------------------
MUL_3638|M.ulcerans_Agy99 HDLNYPWECLRAEPDGAQA-------------------------------
MAB_2119c|M.abscessus_ATCC_199 HDLDYNWDALRTEAPDRVS-------------------------------
Mb2402c|M.bovis_AF2122/97 ADPGYPWGDLGGDPLDGD--------------------------------
Rv2381c|M.tuberculosis_H37Rv ADPGYPWGDLGGDPLDGD--------------------------------
TH_3022|M.thermoresistible__bu SDPGYDWRAVTPAGPD----------------------------------
MSMEG_4512|M.smegmatis_MC2_155 ADAGYRWRDQLGDCHA----------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 ADPAYRWGDLLTGEPE----------------------------------
Mflv_2695|M.gilvum_PYR-GCK HDAEFPWHDVIDTTRP----------------------------------
MAV_2012|M.avium_104 ADPGYRWSETVPTRNQP---------------------------------
MLBr_02354|M.leprae_Br4923 TESDSAKGRLVDLPPTPWQHSRFWVADRSAMSELAVAHPLLGVHVEMPGS
:
MMAR_3695|M.marinum_M ----------------------LPLLDFPNTRMNEIRLWLPYDEVLPRRQ
MUL_3638|M.ulcerans_Agy99 ----------------------LPMLDFPNTRMNEIRLWLPYDEVLPRRQ
MAB_2119c|M.abscessus_ATCC_199 ----------------------LPLRDFPNVQNNDIPLWLSYRADTSGVA
Mb2402c|M.bovis_AF2122/97 ----------------------VDLSGFPNAPMRAVPMWAHPEPLPP---
Rv2381c|M.tuberculosis_H37Rv ----------------------VDLSGFPNAPMRAVPMWAHPEPLPP---
TH_3022|M.thermoresistible__bu -----------------------RLTGFPNAPMRAIPMWATAAPRRIGRA
MSMEG_4512|M.smegmatis_MC2_155 -----------------------VLPDFPFAPMRAEHLWAQPDPLPP---
Mvan_3846|M.vanbaalenii_PYR-1 -----------------------PLFGFPGAPMRAEHLWAEPEPLPV---
Mflv_2695|M.gilvum_PYR-GCK -----------------------ALRGFPNAPMRSVHLWALPQPLPA---
MAV_2012|M.avium_104 -----------------------ALHGFPNAPMRATHLWAAPDRVTEAAP
MLBr_02354|M.leprae_Br4923 GDHGWQADVGTDVCPWLADHKVFGQPIMPAAAFAEIAVAAASEALGVPAG
:* . :
MMAR_3695|M.marinum_M PP------------SVSVAPAAPSVPDATADTTPARLLVEEWVRLSQ---
MUL_3638|M.ulcerans_Agy99 PP------------SVSVAPAAPSVPDATADTTPARLLVEEWVRLSQ---
MAB_2119c|M.abscessus_ATCC_199 VPKQ----------PIVTPEAERRVEMGNDSRAYPRLLREAWAKVTR---
Mb2402c|M.bovis_AF2122/97 -------------------------------VSGLTIAVERWERMVP---
Rv2381c|M.tuberculosis_H37Rv -------------------------------VSGLTIAVERWERMVP---
TH_3022|M.thermoresistible__bu GG------------------------VRGEEAPGLRIAAEVWEPVAAQ--
MSMEG_4512|M.smegmatis_MC2_155 -------------------------------VTGLTVAAEQWHQVAV---
Mvan_3846|M.vanbaalenii_PYR-1 -------------------------------APGLTVTTETWRQRRP---
Mflv_2695|M.gilvum_PYR-GCK -------------------------------PPSLTLATEAWEPHRP---
MAV_2012|M.avium_104 -------------------------------RPRLTVAVEDWRHTTS---
MLBr_02354|M.leprae_Br4923 TSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKIRVEIYSRSPRGDF
: * :
MMAR_3695|M.marinum_M ---------------RSLTPPRVVGIVDPTGACAQLATAMTAAAHQAGAT
MUL_3638|M.ulcerans_Agy99 ---------------RSLTPPRVVGIVDPTGACAQLATAMTAAAHQAGAT
MAB_2119c|M.abscessus_ATCC_199 ---------------RSMMPPRSYAFIDGTGDAGALVEALRDSAPNFGSS
Mb2402c|M.bovis_AF2122/97 -------------STPVAGRHRHLAVLDLGA-HRALAQTLCAAIDSH---
Rv2381c|M.tuberculosis_H37Rv -------------STPVAGRHRHLAVLDLGA-HRALAQTLCAAIDSH---
TH_3022|M.thermoresistible__bu ------------PGPASAATPVPVALLELGD-TGRLGGWLRELLGNR---
MSMEG_4512|M.smegmatis_MC2_155 -------------PEVSG--HHRIAVVGLDS-ECAVAGHLRDAAERI---
Mvan_3846|M.vanbaalenii_PYR-1 -------------RRVSAKVSRRVAVIESGS-GTAISRSLRQAIDRR---
Mflv_2695|M.gilvum_PYR-GCK --------------AERGLALRRTAVLDLAGPRGGLGDLLRDAVDHH---
MAV_2012|M.avium_104 ------------------PTTPTAADLGFAG-AHPMTRRLADAAAAQ---
MLBr_02354|M.leprae_Br4923 SRHATANVEHVSHNAVQPFQQAPGSSNGVTVSPADFYAVLRQTGQHHGPV
. . :
MMAR_3695|M.marinum_M ARVVNGENDGTGADVNTLVILLPETPKLD--------GRAAAAEVGGFFS
MUL_3638|M.ulcerans_Agy99 ARVVNGENDGTGADVNTLVILLPETPKLD--------GRAAAAEVGGFFS
MAB_2119c|M.abscessus_ATCC_199 ARIVTGTDESGIGDADTVVIVLPSPALLD--------DHEAADAVARFFG
Mb2402c|M.bovis_AF2122/97 ----PDTELSAARDAELILVIAPDFEHTD--------AVRAAGALADLVG
Rv2381c|M.tuberculosis_H37Rv ----PDTELSAARDAELILVIAPDFEHTD--------AVRAAGALADLVG
TH_3022|M.thermoresistible__bu ----PDVVLVGPEAAEVAVVAAPESDTAA--------PEAGVAAITELVR
MSMEG_4512|M.smegmatis_MC2_155 ----EGVEVVAPAAADTLLVVAPMISEND--------PVLAGEELGRRID
Mvan_3846|M.vanbaalenii_PYR-1 ----ADLSVAGAADADLAIVVAPTFAGAD--------AAGCVNELSGAID
Mflv_2695|M.gilvum_PYR-GCK ----PGMVSTPVHDADLVLAVAPNLGDPD--------VRESVAALTALID
MAV_2012|M.avium_104 ----GGCRVVAPGEAEIVAIVAPELDQLD--------AVAAVEQIGARED
MLBr_02354|M.leprae_Br4923 FAVLTRITRLLDGSAETEITLPDEVPRHPGYRLHPVVLDAALQSVGAAIP
.: :
MMAR_3695|M.marinum_M N-------------------------------------------------
MUL_3638|M.ulcerans_Agy99 N-------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 N-------------------------------------------------
Mb2402c|M.bovis_AF2122/97 AG------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv AG------------------------------------------------
TH_3022|M.thermoresistible__bu AG------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 EG------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 TG------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK DG------------------------------------------------
MAV_2012|M.avium_104 AG------------------------------------------------
MLBr_02354|M.leprae_Br4923 DGEVAESAEVSYLPVSFEAIRVYRDIGRHALCRARLTNLDGGTGKLGKIV
MMAR_3695|M.marinum_M ---------------------------------------------RAWWP
MUL_3638|M.ulcerans_Agy99 ---------------------------------------------RAWWP
MAB_2119c|M.abscessus_ATCC_199 ---------------------------------------------RTWWP
Mb2402c|M.bovis_AF2122/97 --------------------------------------------LLDYPM
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------LLDYPM
TH_3022|M.thermoresistible__bu --------------------------------------------GLRYPA
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------LLRYPD
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------LLGYAD
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------LLRYPD
MAV_2012|M.avium_104 --------------------------------------------LPDYRG
MLBr_02354|M.leprae_Br4923 LIDDAGYVAAEVDGIYLRRIERRVVPLPLAQKIFDAEWIESPIPASRALE
MMAR_3695|M.marinum_M GVDTGVTDCWLVTV------------------------------------
MUL_3638|M.ulcerans_Agy99 GVDTGVTDCWLVTV------------------------------------
MAB_2119c|M.abscessus_ATCC_199 RLSSTVTGCWLVTV------------------------------------
Mb2402c|M.bovis_AF2122/97 HIGARCQSVCLVTV------------------------------------
Rv2381c|M.tuberculosis_H37Rv HIGARCQSVCLVTV------------------------------------
TH_3022|M.thermoresistible__bu APGPHCRDVWLVTV------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 LLTETTRDVWLVTG------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 TFGPRCRDVWLVTV------------------------------------
Mflv_2695|M.gilvum_PYR-GCK DVGTDCRDLWLVTT------------------------------------
MAV_2012|M.avium_104 LIGPRCRAVWLLTV------------------------------------
MLBr_02354|M.leprae_Br4923 QITETARASWLVLTDWDPSIKSLTDEFIARWRSPMRRVYTANLHDESAML
*:
MMAR_3695|M.marinum_M --------------------------------------------------
MUL_3638|M.ulcerans_Agy99 --------------------------------------------------
MAB_2119c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2402c|M.bovis_AF2122/97 --------------------------------------------------
Rv2381c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4512|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2012|M.avium_104 --------------------------------------------------
MLBr_02354|M.leprae_Br4923 AAFAETAGDPEHPPIGVVIFVGGAATGLDDGLVQARDSVWSISTVVRAIV
MMAR_3695|M.marinum_M --------------GGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFR
MUL_3638|M.ulcerans_Agy99 --------------GGEAATAADGPPDPVHAAASAGFRSIGAEHPDVGFR
MAB_2119c|M.abscessus_ATCC_199 --------------GGEQAIADDGPAHPVHAAIAAGFRCMGTEHPGIAFR
Mb2402c|M.bovis_AF2122/97 --------------GAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFS
Rv2381c|M.tuberculosis_H37Rv --------------GAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFS
TH_3022|M.thermoresistible__bu --------------GAEQVHPDDPVAPV-PAAVAAMHRSLGLENPQIPFH
MSMEG_4512|M.smegmatis_MC2_155 --------------RGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFR
Mvan_3846|M.vanbaalenii_PYR-1 --------------GAENVTAEDPAPDLGQAGVAALHRCIGFEHPDQSFH
Mflv_2695|M.gilvum_PYR-GCK --------------AAEQLTG-DPTPRPAQAALAAMHRSIGFEYPDRAFR
MAV_2012|M.avium_104 --------------RAEHVDGDDDQACVAQAALAAMHRSIGFEFPDQAFG
MLBr_02354|M.leprae_Br4923 STWHGRSPRLWLIAGGGLSVQDDELGAPATAALKGLVRVLALENPDLRAT
. *. . * :. * *
MMAR_3695|M.marinum_M HLDLPAG--------ATAQDWAHPIVAALHTANEPELAYRDGAF------
MUL_3638|M.ulcerans_Agy99 HLDLPAG--------ATAQDWAHPIVAALHTANEPELAYRDGAF------
MAB_2119c|M.abscessus_ATCC_199 HLDLTSD--------IASPDKADNILAALQSAGESELALRADGM------
Mb2402c|M.bovis_AF2122/97 HLDLPS-------WDLDPVLGVSVITAVLRGFG--ETALRGSVN---GYT
Rv2381c|M.tuberculosis_H37Rv HLDLPS-------WDLDPVLGVSVITAVLRGFG--ETALRGSVN---GYT
TH_3022|M.thermoresistible__bu HLDLEQGVGSDTARDTDPAVAALLMDAVLSATGGGGLAIRTTGA---GAV
MSMEG_4512|M.smegmatis_MC2_155 QLDVPMGL--------DTEAAVTAVAAMVTGTT--DLALRCDVADGPGTT
Mvan_3846|M.vanbaalenii_PYR-1 HLDLPAG----------ATDALGAVDVMVDGAG--ELALRRDGQ------
Mflv_2695|M.gilvum_PYR-GCK HLDLPPVV-------LDEAAASAALDAVLGGGD--DLALRDIDG---MPA
MAV_2012|M.avium_104 HVDLPHR-------DVDAATAYAIIEVLLAEPA--EVALRGEQS----PR
MLBr_02354|M.leprae_Br4923 LLDLDATQD------QIAALTAELHNSASEFGGDDVIAWRGQHR------
:*: * *
MMAR_3695|M.marinum_M -YAKRIVAG-EGAVVHGAG-ACPEHVLIIGGTGNLGLEFCDHFAHRGARR
MUL_3638|M.ulcerans_Agy99 -YAKRIVAG-EGAVVHGAG-ACPEHVLIIGGTGNLGLESCDHFAHRGARR
MAB_2119c|M.abscessus_ATCC_199 -YAKRVLDIDQDGDESSRV-VAPAHVVITGGTGKLGQEFCEHYARMGTRQ
Mb2402c|M.bovis_AF2122/97 LFERTLADAPAVPNWSLDS-GVLDDVVVTGGAGAIGMHYARYLAEHGARR
Rv2381c|M.tuberculosis_H37Rv LFERTLADAPAVPNWSLDS-GVLDDVVVTGGAGAIGMHYARYLAEHGARR
TH_3022|M.thermoresistible__bu LYRRGLRDVPAPP--PLDRPGLLDEVVITGGAGAIGLHYARQLARRGAKR
MSMEG_4512|M.smegmatis_MC2_155 LWRRGMRDASAAAAPWP--TGVLDDVVITGGTGAVGLQFARRLAALGARR
Mvan_3846|M.vanbaalenii_PYR-1 VYERTLGDDTSTAPPWDLSSGTLDNVVITGGSGAIGLSFARFLAARGARR
Mflv_2695|M.gilvum_PYR-GCK VFARTEHETVTTPESWADDPGALDHVVITGGSGTVGQHYARHLAERGARR
MAV_2012|M.avium_104 RHVRTFRAHHESADRPLDD-AALEHVVITGGSGAIGLHYARYCLQRGARN
MLBr_02354|M.leprae_Br4923 -FVERLCKATLDAGKDNPVVRPGAAYIVTGGLGGLGLVVARWLVDRGAGR
. :: ** * :* . *: .
MMAR_3695|M.marinum_M ITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVS--------
MUL_3638|M.ulcerans_Agy99 ITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVS--------
MAB_2119c|M.abscessus_ATCC_199 ITLISRSGETDAVTGRLDAIRRSTGAKVRALPCDVTDTAAVT--------
Mb2402c|M.bovis_AF2122/97 IVLLSRRA---ADQATVAMLRKQHGTVIVSPPCDITDPTQLS--------
Rv2381c|M.tuberculosis_H37Rv IVLLSRRA---ADQATVAMLRKQHGTVIVSPPCDITDPTQLS--------
TH_3022|M.thermoresistible__bu IVLLSRRP---VDPAELAALAAPTGAEVLSVSCDLTDPDAVXXXXVRAVL
MSMEG_4512|M.smegmatis_MC2_155 IVLLSRNG---IEGNRVDEL--PLGVEIVAPRCDLTDIPRVR--------
Mvan_3846|M.vanbaalenii_PYR-1 IVLLSRRG---AGPAPLDN----LGAEIIAPACDLRDPRQLA--------
Mflv_2695|M.gilvum_PYR-GCK ITLLSRHG---AKGS------AAGGPGVQTVCCDVTDPVALA--------
MAV_2012|M.avium_104 LTLLSRNG---IEAAVLRELTGSHDARVSAPRCDITDRAAVT--------
MLBr_02354|M.leprae_Br4923 VVLGSRSD--PTEEQRKTLVELEARAEIVFLRGDVTSPGVAES-------
:.* ** : *: .
MMAR_3695|M.marinum_M ------------------------------RLAAQHRSTP----------
MUL_3638|M.ulcerans_Agy99 ------------------------------RLAAQHRSTP----------
MAB_2119c|M.abscessus_ATCC_199 ------------------------------ALADQLRDTP----------
Mb2402c|M.bovis_AF2122/97 ------------------------------AIAAEYGGVG----------
Rv2381c|M.tuberculosis_H37Rv ------------------------------AIAAEYGGVG----------
TH_3022|M.thermoresistible__bu TAAERAHRHGGDPREVLWQAWHRSGLQRRWLAASERGGVAGVQADRDLDA
MSMEG_4512|M.smegmatis_MC2_155 ------------------------------DVAAEFGGQG----------
Mvan_3846|M.vanbaalenii_PYR-1 ------------------------------ATVAEFAGGP----------
Mflv_2695|M.gilvum_PYR-GCK ------------------------------VAAAEFGGDG----------
MAV_2012|M.avium_104 ------------------------------EAAARYAGSG----------
MLBr_02354|M.leprae_Br4923 ------------------------------LVAAAGRAGG----------
.
MMAR_3695|M.marinum_M --------ADLIIHAAVAYASV----------EFSDITTDDADNALYAK-
MUL_3638|M.ulcerans_Agy99 --------ADLIIHAAVAYASV----------EFSDITTDDADNALYAK-
MAB_2119c|M.abscessus_ATCC_199 --------ADLIVHAAVDYSDT----------PLSEVTTNKFQDALRAK-
Mb2402c|M.bovis_AF2122/97 --------ASLIVHAAGSVISG----------TAPGVTSAAVVDNFAAK-
Rv2381c|M.tuberculosis_H37Rv --------ASLIVHAAGSVISG----------TAPGVTSAAVVDNFAAK-
TH_3022|M.thermoresistible__bu VTAFFDAAEQYVARTAGATLRGLIDHLTTLGPAAPARDQSARRDAVAVLS
MSMEG_4512|M.smegmatis_MC2_155 --------ASLIVHAAATATIA----------AGSALTGAAAQATFTAK-
Mvan_3846|M.vanbaalenii_PYR-1 --------ASLIIHAAGTATFA----------NRADITGAALADMAGAK-
Mflv_2695|M.gilvum_PYR-GCK --------ATLVIHAAGTAQFA----------EHDTLSAAAFADTAAAK-
MAV_2012|M.avium_104 --------ATLLIHTAGIAQAR----------SRTDLTGADVAAVCAAK-
MLBr_02354|M.leprae_Br4923 -------QLRGIVHGAAVIEDS----------LVFTMTRENLERVWAPK-
: : *
MMAR_3695|M.marinum_M ------------------------------VVGIGQVLDAFP--------
MUL_3638|M.ulcerans_Agy99 ------------------------------VVGIGQVLDAFP--------
MAB_2119c|M.abscessus_ATCC_199 ------------------------------VIGISNVLDTVP--------
Mb2402c|M.bovis_AF2122/97 ------------------------------VLGLAQMIELWP--------
Rv2381c|M.tuberculosis_H37Rv ------------------------------VLGLAQMIELWP--------
TH_3022|M.thermoresistible__bu AHAALDREWDLVVIAGLQDGLWPNTVPRGGVLATQQLVDVLDGVADGSDP
MSMEG_4512|M.smegmatis_MC2_155 ------------------------------LAGIENVLAAWP--------
Mvan_3846|M.vanbaalenii_PYR-1 ------------------------------IIGLEALTRTWP--------
Mflv_2695|M.gilvum_PYR-GCK ------------------------------VEGLFRIAEAWP--------
MAV_2012|M.avium_104 ------------------------------VRGLALMADVWP--------
MLBr_02354|M.leprae_Br4923 ------------------------------ATGALRMHQASVS-------
. :
MMAR_3695|M.marinum_M -------RTDGCRIVLCSSARATIGGRGQVMYAAAN----RMLDAMAHRL
MUL_3638|M.ulcerans_Agy99 -------RTDGCRIVLCSSARATIGGRGQVMYAAAN----RMLDAMAHRL
MAB_2119c|M.abscessus_ATCC_199 -------RTDSCRVMLCSSLAATIGGKGQLMYAAGN----RMLDVLASTR
Mb2402c|M.bovis_AF2122/97 -------LRPDVRTLLCSSVMGVWGGHGVVAYSAAN----RLLDVMAAQL
Rv2381c|M.tuberculosis_H37Rv -------LRPDVRTLLCSSVMGVWGGHGVVAYSAAN----RLLDVMAAQL
TH_3022|M.thermoresistible__bu VVSRRAPLLAEERRLLIAAMGRARSRLLVTAVDSDDGDESLLPSPFCAEL
MSMEG_4512|M.smegmatis_MC2_155 -------VRPDARILLCSSVSGLWGGHGHAAYAAAN----RLLDVMAERL
Mvan_3846|M.vanbaalenii_PYR-1 -------IRDDARILLCSSVTGVWGGKGVGGYAAAN----RMLDVMAARL
Mflv_2695|M.gilvum_PYR-GCK -------RRPGARMLVCSSVSGLWGGRGHAAYAAAN----RLVDVTAAQM
MAV_2012|M.avium_104 -------LRPDCRILACSSVFGVWGGYHHAAYAASN----RMLDVLATQL
MLBr_02354|M.leprae_Br4923 --------CELDWWLGFSSVASLLGSPGQAAYACAS----AWLDALVMWR
: :: . . . .
MMAR_3695|M.marinum_M RAEGLDCVSVQWG--------------------QWTVH-------FDLDA
MUL_3638|M.ulcerans_Agy99 RAEGLDCVSVQWG--------------------QWTVH-------FDLDA
MAB_2119c|M.abscessus_ATCC_199 RASGLDCTSIQWG--------------------QWTVH-------LDLGD
Mb2402c|M.bovis_AF2122/97 RAQGRHCVAVKWG--------------------LWQAPKAGEPARGIADA
Rv2381c|M.tuberculosis_H37Rv RAQGRHCVAVKWG--------------------LWQAPKAGEPARGIADA
TH_3022|M.thermoresistible__bu AALATEPEAATPAPLPAPRVLTAAALVGRLRSVVCAAPDTVDDEVRAGAA
MSMEG_4512|M.smegmatis_MC2_155 RSEGRRCTAVRWG--------------------LWPG-------AGIIDA
Mvan_3846|M.vanbaalenii_PYR-1 GADGRNCTAVRFG--------------------LWEG-------SGIVDA
Mflv_2695|M.gilvum_PYR-GCK RAEGIRCAAVRFG--------------------LFGT--------GIVDE
MAV_2012|M.avium_104 RARGLDCTAIRWG--------------------LWQD-------AGVVAG
MLBr_02354|M.leprae_Br4923 KASGLPSAVINWG--------------------PWSDVGVAQALVGSVLD
: . .
MMAR_3695|M.marinum_M SSMAQLAAIGVIPMPPAEAIALGMQRLG----------------------
MUL_3638|M.ulcerans_Agy99 SSMAQLAAIGVIPMPPAEAIALGMQRLG----------------------
MAB_2119c|M.abscessus_ATCC_199 AGIAKLAAAGVHPMRPADALAVGMGHHH----------------------
Mb2402c|M.bovis_AF2122/97 VTIARVERSGLRQMAPQQAIEASLHEF-----------------------
Rv2381c|M.tuberculosis_H37Rv VTIARVERSGLRQMAPQQAIEASLHEF-----------------------
TH_3022|M.thermoresistible__bu TQLARLAAAGVPGADPAQWYAMTPLSTGEPLWDGPGQSVTLSPSTLQTLV
MSMEG_4512|M.smegmatis_MC2_155 DEITRVERSGLRAMAPDRAVDTALQDFA----------------------
Mvan_3846|M.vanbaalenii_PYR-1 AEIARVERTGLRQMKPELAVEASLCDFP----------------------
Mflv_2695|M.gilvum_PYR-GCK ESVNLIGRSGLVPLDPDDAVAASLRDLP----------------------
MAV_2012|M.avium_104 SEIARTERSGLVAMDPRRALQASLHRYE----------------------
MLBr_02354|M.leprae_Br4923 TITPAEGIEAIDSLLAAGRTRTGVARLR----------------------
.: .
MMAR_3695|M.marinum_M ----------------------RNAIVAAFDFDRAR--------------
MUL_3638|M.ulcerans_Agy99 ----------------------RNAIVAAFNFDRAR--------------
MAB_2119c|M.abscessus_ATCC_199 ----------------------GNTLVGAFDLTQAR--------------
Mb2402c|M.bovis_AF2122/97 ---------------------TVDPLVFAADAAR----------------
Rv2381c|M.tuberculosis_H37Rv ---------------------TVDPLVFAADAAR----------------
TH_3022|M.thermoresistible__bu DCPLRWLLERHGGTDGRDVRSTVGSLVHALAAGRYRTEGQLLAELERVWD
MSMEG_4512|M.smegmatis_MC2_155 ----------------------GDPLVFSADAQR----------------
Mvan_3846|M.vanbaalenii_PYR-1 ----------------------RDPLVLAADRDR----------------
Mflv_2695|M.gilvum_PYR-GCK ----------------------GDPIVYSADRAR----------------
MAV_2012|M.avium_104 ----------------------SDPLIFDADFER----------------
MLBr_02354|M.leprae_Br4923 ----------------------ADKALVAFPEMRSIS-------------
. : :
MMAR_3695|M.marinum_M ------------------PVLETFGYGPLVS-------------------
MUL_3638|M.ulcerans_Agy99 ------------------PVLETFGYGPLVS-------------------
MAB_2119c|M.abscessus_ATCC_199 ------------------AMLGVFGYGPLLS-------------------
Mb2402c|M.bovis_AF2122/97 --------------------LQMLLDSRQ---------------------
Rv2381c|M.tuberculosis_H37Rv --------------------LQMLLDSRQ---------------------
TH_3022|M.thermoresistible__bu QLPFESRWYADNELSRHRAMLQTFMRWRERTRRELTEVAAEIAVDGVLVD
MSMEG_4512|M.smegmatis_MC2_155 --------------------LALFLGTDA---------------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------------MRMFFGEKP---------------------
Mflv_2695|M.gilvum_PYR-GCK --------------------LQIFRDDPAP--------------------
MAV_2012|M.avium_104 --------------------LQVFFESQG---------------------
MLBr_02354|M.leprae_Br4923 -------------------YFTWVVEQLAAAG------------------
: .
MMAR_3695|M.marinum_M ------------ELLS---PVS----ETAAPAEPAD--------LPGRLS
MUL_3638|M.ulcerans_Agy99 ------------ELLS---PVS----ETAAPAEPAD--------LPGRLS
MAB_2119c|M.abscessus_ATCC_199 ------------ELEDNGGPVAPAETTRPAPVVSEN--------RSGHLV
Mb2402c|M.bovis_AF2122/97 -------------FERYEGPTDPNLTIVDAVR------------------
Rv2381c|M.tuberculosis_H37Rv -------------FERYEGPTDPNLTIVDAVR------------------
TH_3022|M.thermoresistible__bu GADTTPEIRVRGRLDRLERDADGRLVVVDLKTGKSPVTKNDAQRHAQLAM
MSMEG_4512|M.smegmatis_MC2_155 -------------DTGTGREATHAAQHRDAGPPADA----EHHDTGAAVR
Mvan_3846|M.vanbaalenii_PYR-1 -------------VEKPGEADTGAGPASMAPP--------------DAVR
Mflv_2695|M.gilvum_PYR-GCK --------------PTATSPASGGDTTAVVLA------------------
MAV_2012|M.avium_104 -------------MPMPFSDTPTRDDEAAAAPAGKP--------LAEVVR
MLBr_02354|M.leprae_Br4923 ------------DLGDWVGSDTLADLDPAEAQRVVT----------ERMC
MMAR_3695|M.marinum_M NLLAAAIGAERAERIDTSVPMVALGLDSLQALELRRR----VKAEFDHEL
MUL_3638|M.ulcerans_Agy99 NLLAAAIGAERAERIDTSVPMVALGLDSLQALELRRR----VKAEFDHEL
MAB_2119c|M.abscessus_ATCC_199 QLLAEVIGADHADSIDTAMPMVAMGLDSLQALEFRRR----VQAELDFEL
Mb2402c|M.bovis_AF2122/97 TQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNR----LKRSIGATV
Rv2381c|M.tuberculosis_H37Rv TQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNR----LKRSIGATV
TH_3022|M.thermoresistible__bu YQLAVAAGLLPAGDIPGGGRLVYLGRPTGGGATEREQDPLTPETAAGWRD
MSMEG_4512|M.smegmatis_MC2_155 IALAAVLKLADTTGLDLDASLLDLGVDSLLALDLRKK----LKKTTGRSV
Mvan_3846|M.vanbaalenii_PYR-1 TQLAAVLD-VDAAALDLDSPLFDLGVDSLLALDLRKR----LKRLTGHTV
Mflv_2695|M.gilvum_PYR-GCK -ELTSVLGIEPAG-VDLDASLLDMGVDSLLALDLRKR----LRRATGRSV
MAV_2012|M.avium_104 AELAATLHLGDSVSIDPSASLIDLGVDSLLALDLRKR----LRRTVGNSV
MLBr_02354|M.leprae_Br4923 ALIAAVMGYADRSTVNPAVPLTELGLDSLMAVRIRNG----ARADFGVEP
:: . : : :* : . *. . .
MMAR_3695|M.marinum_M EVSDLLGGASIADVLAQLGSR-----------------------------
MUL_3638|M.ulcerans_Agy99 EVSDLLGGASIADVLAQLGSR-----------------------------
MAB_2119c|M.abscessus_ATCC_199 PVQDLLGGASVDHVIDALTAQSR---------------------------
Mb2402c|M.bovis_AF2122/97 SLATLMGDITGDGLVAKLEDADER-----SHTAQKVDISRD---------
Rv2381c|M.tuberculosis_H37Rv SLATLMGDITGDGLVAKLEDADER-----SHTAQKVDISRD---------
TH_3022|M.thermoresistible__bu TVAQAADATRGPRFAARINDGCAHCPVRFSCPAQAAQAGSERP-------
MSMEG_4512|M.smegmatis_MC2_155 PLATLLGGVTATELIEHLER------------PEKETFSRD---------
Mvan_3846|M.vanbaalenii_PYR-1 PLATLLGGITGADLIAGLS--------------EKVNTSSD---------
Mflv_2695|M.gilvum_PYR-GCK PLAAMLGGMTGAELITGLDD-----------EPQRNEIPA----------
MAV_2012|M.avium_104 PVARMLGGITVAELVDALRADATGGPVVPPTIQRTGAVSGAHPSKLAMLE
MLBr_02354|M.leprae_Br4923 PVTLILQGASLQDLTADVVRQLGLAGPKQALENADTVRDRVQQRAAVRRG
: . :
MMAR_3695|M.marinum_M --------------
MUL_3638|M.ulcerans_Agy99 --------------
MAB_2119c|M.abscessus_ATCC_199 --------------
Mb2402c|M.bovis_AF2122/97 --------------
Rv2381c|M.tuberculosis_H37Rv --------------
TH_3022|M.thermoresistible__bu --------------
MSMEG_4512|M.smegmatis_MC2_155 --------------
Mvan_3846|M.vanbaalenii_PYR-1 --------------
Mflv_2695|M.gilvum_PYR-GCK --------------
MAV_2012|M.avium_104 RLDS----------
MLBr_02354|M.leprae_Br4923 AVMRRRPKPDVQGG