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MTGTTTTLIVGAGFAGIGTAIRLLQEGTDDFVILERSNRVGGTWRDNTYPGAACDIPSLLYSYSFEPNPG WTHTYSGSAEILEYIDTIVTKYDLARFIQFDTDVTALEFDEGAGIWVADTADGKRYQARSVVMASGPLAD ASFPDIRGIDSYEGKKIHSARWDQGYDLGDKRVAVIGTGASAVQILPELVKSAASVKVFQRTPGWVLPRV NLKHPAWARSTFKQLPVSEQALRDAWFWAHEVMAVGMVWNTAATSAIQLAAKAHLRRQVKDPWLRRQLTP HFRPGCKRMLMTSDYYPALQSDNCKLISWPIATLSPNGVRTADGVEHEVDCIVFATGFDVCKRGTPFPIS GLGGRKLGDEWSQGRYAFKSVSVAGYPNLFFTFGPNSGPGHNSALVYMEAVIDYVVKAIKLLQQNDIGTL DVREDRQGRYHSEIQRRLRRTTWNSGCSSWYLTEDGYNGTMYPGFATQFMRELSRLDPRDYVITRRDDAH LRLTQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2073 | - | - | 100% (495) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4476c | - | 0.0 | 69.58% (480) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_3920c | - | e-113 | 42.44% (476) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3075c | - | 1e-113 | 44.10% (483) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4608 | - | 0.0 | 73.97% (484) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv3049c | - | 1e-113 | 44.10% (483) | monooxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 1e-24 | 23.18% (440) | putative monooxygenase |
| M. marinum M | MMAR_3139 | - | 0.0 | 83.30% (497) | monooxygenase |
| M. avium 104 | MAV_1795 | - | 0.0 | 61.17% (479) | flavin-binding monooxygenase |
| M. smegmatis MC2 155 | MSMEG_2310 | - | 1e-115 | 43.63% (479) | monooxygenase |
| M. thermoresistible (build 8) | TH_4080 | - | 1e-114 | 43.84% (479) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1880 | - | 1e-114 | 43.84% (479) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_1519 | - | 1e-177 | 62.10% (467) | FAD dependent oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3075c|M.bovis_AF2122/97 ---MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQGVD
Rv3049c|M.tuberculosis_H37Rv ---MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQGVD
MUL_1880|M.ulcerans_Agy99 MTDVVIPSTETTASGEPQAPTPPVKTRAVIIGTGFSGLGMAIALQKQGVD
TH_4080|M.thermoresistible__bu ---MTVTEPSADITPANTPTQPPVRTRALIVGTGFSGLGMAIALQRRGID
MSMEG_2310|M.smegmatis_MC2_155 ---------------MTAADQQPIRTRALVIGTGFSGLGMAIELQRRGVD
MAB_2073|M.abscessus_ATCC_1997 ---------------------MTGTTTTLIVGAGFAGIGTAIRLLQEGTD
MMAR_3139|M.marinum_M ---------------------MTDTVTTLIVGAGFAGIGTAMRMLQAGVN
Mflv_4608|M.gilvum_PYR-GCK ---------------------MSDTTTVLIVGAGFAGLGTAIRLLQQGID
MAV_1795|M.avium_104 -------------------MARDHAHAALIIGAGFTGLGAAIRLAEAGVD
Mvan_1519|M.vanbaalenii_PYR-1 ----------------------MHVHDTLIVGAGFSGLGTAIKLRQAGVD
MLBr_00065|M.leprae_Br4923 ----------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPN
.:::*:*::*:. * : :
Mb3075c|M.bovis_AF2122/97 --FVILEKADDVGGTWRDNTYPGCACDIPSHLYSFSFEPKADWKHLFSYW
Rv3049c|M.tuberculosis_H37Rv --FVILEKADDVGGTWRDNTYPGCACDIPSHLYSFSFEPKADWKHLFSYW
MUL_1880|M.ulcerans_Agy99 --FVILEKSDDVGGTWRDNSYPGCACDIPSHLYSFSFEPKPDWRNPFSYQ
TH_4080|M.thermoresistible__bu --FLMLEKADDIGGTWRDNTYPGCACDIPSHLYSFSFEPKADWRHLFSYQ
MSMEG_2310|M.smegmatis_MC2_155 --FLILEKADEIGGTWRDNTYPGCACDIPSHMYSFSFEPKADWKHMWSFQ
MAB_2073|M.abscessus_ATCC_1997 D-FVILERSNRVGGTWRDNTYPGAACDIPSLLYSYSFEPNPGWTHTYSGS
MMAR_3139|M.marinum_M D-FVILERSHRVGGTWRDNTYPGAACDIPSLLYSYSFEPNPGWTRAYSGS
Mflv_4608|M.gilvum_PYR-GCK D-FVVLERADEVGGTWRDNTYPGAACDIPSLLYSYGFEQNPDWSRAYSGS
MAV_1795|M.avium_104 D-IVILERADRVGGTWRDTTYPGASCDVPSLLYSYSFVKNPTWSRTYSPA
Mvan_1519|M.vanbaalenii_PYR-1 D-IVIVERGQRVGGTWRDNTYPGVACDIPSLLYSFSFVRNPSWSRAYPTG
MLBr_00065|M.leprae_Br4923 KSYVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADG
:::*: :**** *** .* .: * . .
Mb3075c|M.bovis_AF2122/97 DEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADG---RE
Rv3049c|M.tuberculosis_H37Rv DEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADG---RE
MUL_1880|M.ulcerans_Agy99 PEIWDYLKGVTEKYGLRRYVEFNSLVDRAYWDDEECRWHVFTSDG---RE
TH_4080|M.thermoresistible__bu DEIQEYLQGVTAKYGLRRYIHFDSLVDRAHWDDTEHRWHVFTADG---RE
MSMEG_2310|M.smegmatis_MC2_155 PEIQDYLLGVTAKYGLRRHIHFNSHVDRAHWDDEELRWHVFTKTG---QE
MAB_2073|M.abscessus_ATCC_1997 AEILEYIDTIVTKYDLARFIQFDTDVTALEFDEGAGIWVADTADG---KR
MMAR_3139|M.marinum_M AEILAYIDAIVAKYDLGRFIHFGADVSALEFDEDAGEWVVDTTGG---RR
Mflv_4608|M.gilvum_PYR-GCK AEILGYIKTMVDKYSLSRFIRFGVNVTGLEFDEESALWTAQTADG---SQ
MAV_1795|M.avium_104 PEIYRHLEDMADRFDIRRRIRFGHEVSGLAFDEDAGVWTATTKNR---KK
Mvan_1519|M.vanbaalenii_PYR-1 AEICDHIEDMADQHGLTPLIRFDTEVTGLTFDDQSGAWTVTTKRR---KQ
MLBr_00065|M.leprae_Br4923 KPILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRM
* :: . ..: :.:. * :.. * . .
Mb3075c|M.bovis_AF2122/97 YVAQFLISGAGALHIPS--FPEIAGRDEFAGPAFHSAQWDHSIDLTGKRV
Rv3049c|M.tuberculosis_H37Rv YVAQFLISGAGALHIPS--FPEIAGRDEFAGPAFHSAQWDHSIDLTGKRV
MUL_1880|M.ulcerans_Agy99 YVAQFLISGAGALHIPS--SPEIEGREEFAGPAFHSAEWDHSVDLTGKRV
TH_4080|M.thermoresistible__bu YIAQFLISCAGALHIPS--IPDFPGRDQFAGPAFHSAQWDHSVDLTGKRV
MSMEG_2310|M.smegmatis_MC2_155 YIAQFLVSGAGGLHIPQ--IPDIEGRESFAGAAFHSAQWDHSVDLRGKRV
MAB_2073|M.abscessus_ATCC_1997 YQARSVVMASGPLADAS--FPDIRGIDSYEGKKIHSARWDQGYDLGDKRV
MMAR_3139|M.marinum_M YRGRSVVMASGPLADAS--FPDIRGIESYEGKKIHSARWDHSYDMSGKRV
Mflv_4608|M.gilvum_PYR-GCK FTARTAVMASGPLANAS--LPDIRGLDTFDGHKIHSARWDHDYDMSDKRV
MAV_1795|M.avium_104 FRARTVVLASGPLSDVS--FPDIRGLDSYRGHKIHSARWDHDYDFAGKRV
Mvan_1519|M.vanbaalenii_PYR-1 FRARTVVLASGPLADHR--FPEIRGIDSYRGHKIHSASWDHDYDFTGKRV
MLBr_00065|M.leprae_Br4923 ISCSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNI
. :* * : * : : * :*. * .. * *.:
Mb3075c|M.bovis_AF2122/97 AIVGTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPR-TNEELPVSLRRA
Rv3049c|M.tuberculosis_H37Rv AIVGTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPR-TNEELPVSLRRA
MUL_1880|M.ulcerans_Agy99 AIIGAGASAIQIVPEIVEQ-VGELQLYQRTPPWVVPR-SNPEIPPALRRA
TH_4080|M.thermoresistible__bu AVIGTGASAIQIVPEIIDR-VAQLQLYQRTPAWVVPR-TNDELPAWLRRA
MSMEG_2310|M.smegmatis_MC2_155 AVIGTGASAIQIVPEIVKD-VAELHLYQRTPAWVMPR-VNNAFPQWLRNV
MAB_2073|M.abscessus_ATCC_1997 AVIGTGASAVQILPELVKS-AASVKVFQRTPGWVLPR-VNLKHPAWARST
MMAR_3139|M.marinum_M AVIGTGASAVQIVPELVQL-AASVKVFQRTPGWVLPR-VNFRHPAWARST
Mflv_4608|M.gilvum_PYR-GCK AVIGTGASAVQIIPELVKT-ARSVKVFQRTPGWVLPR-PDFSHPQWVRTA
MAV_1795|M.avium_104 AVIGTGASAIQIIPELVKQ-AGFVKVFQRTPCWVLPR-LDVATPPAVQAL
Mvan_1519|M.vanbaalenii_PYR-1 AVIGTGASAVQIVPELVKT-AAFVKVFQRTPGWVLPR-LDLPMPAAVQAL
MLBr_00065|M.leprae_Br4923 VVIGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRW
.::*:**:*: ::* : . : : **:* :::.: . . .
Mb3075c|M.bovis_AF2122/97 LRTVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKD
Rv3049c|M.tuberculosis_H37Rv LRTVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKD
MUL_1880|M.ulcerans_Agy99 MENVPGLRALARLGIYWAQEALAFGMTKRPNVLKVGEAYAKYNIRRSVKD
TH_4080|M.thermoresistible__bu LENIPGLRLALRGGIYALQEALAVGMTKYPGMLRIGHLLGKWNINRSVKD
MSMEG_2310|M.smegmatis_MC2_155 FSYVPGTRALLRAAIYWIHEGVGFAMTKEPRLLKIGEWMGRYNINRSIKD
MAB_2073|M.abscessus_ATCC_1997 FKQLPVSEQALRDAWFWAHEVMAVGMVWNTAATSAIQLAAKAHLRRQVKD
MMAR_3139|M.marinum_M FKRMPATEQALRGAWFWAHEVMAVGMVWDTAATSVIQAAAKANLRRQVKD
Mflv_4608|M.gilvum_PYR-GCK FRRLPRVQNVGRQAWFWGHELMAVGMVWDTPVTTGIQLLAKANLRRQVSD
MAV_1795|M.avium_104 FAKVPAAQELARQALYWGHEASATALVWDTPLTSLVARLGKAHLRAQVKD
Mvan_1519|M.vanbaalenii_PYR-1 FAKVPATQEIARQALYWGHEASAAALVWNTPMSGLVARLGKAHLRQQVKD
MLBr_00065|M.leprae_Br4923 LPDKYAYTAVRWKNILRQSALYGACQKWP---QRMRNILLGHVARRLPKG
: . . ..
Mb3075c|M.bovis_AF2122/97 RELRRKLTPRYRIGCKRILNS--STYYPAVADPKTELITDRIDRITHDGI
Rv3049c|M.tuberculosis_H37Rv RELRRKLTPRYRIGCKRILNS--STYYPAVADPKTELITDRIDRITHDGI
MUL_1880|M.ulcerans_Agy99 RELRRKLTPHYRIGCKRILNS--SSYYPAVANPKTRLITDRIARITRNGI
TH_4080|M.thermoresistible__bu PQLRAKLTPDYRLGCKRILNS--STYYPAVADPRTEVITESIDRITTDGI
MSMEG_2310|M.smegmatis_MC2_155 PELRRKLTPSYRAGCKRILNS--DTYYRGIADPKTQVITEGIARMTPTGI
MAB_2073|M.abscessus_ATCC_1997 PWLRRQLTPHFRPGCKRMLMT--SDYYPALQSDNCKLISWPIATLSPNGV
MMAR_3139|M.marinum_M TWLRRQLTPQFRPGCKRMLMT--NDYYPALQADNCKLVSWPIATLAPNGI
Mflv_4608|M.gilvum_PYR-GCK TWLRRQLTPNFRAGCKRMLMS--SDYYPALQRDNCKLVSWPIATLSPNGI
MAV_1795|M.avium_104 PWLRRQLTPDFRPGCKRMLVS--SDYYPALQRDNCKLIDWPIATLSPAGI
Mvan_1519|M.vanbaalenii_PYR-1 PWMRRQLTPDFTPGCKRMLIS--SDYYPALQRDNCKLIDWPIATLSPAGI
MLBr_00065|M.leprae_Br4923 YDVQKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVTDAIDRFTSTGI
:: :: * : :*: . : .: :: * :: *:
Mb3075c|M.bovis_AF2122/97 VTADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREG
Rv3049c|M.tuberculosis_H37Rv VTADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREG
MUL_1880|M.ulcerans_Agy99 VTADG----VEHQADVIVYATGFHVTDSYTYVQIKGQHGEDLVDRWNREG
TH_4080|M.thermoresistible__bu VTSDG----TERAVDVIVYATGFHVSDSYKYVQIKGLNGEDIVDRFNREG
MSMEG_2310|M.smegmatis_MC2_155 VTNDG----VEHPVDIVVYATGFHVTDSYTYVDIKGAGGEDLVDRWNREG
MAB_2073|M.abscessus_ATCC_1997 RTADG----VEHEVDCIVFATGFDVCKRGTPFPISGLGGRKLGDEWS-QG
MMAR_3139|M.marinum_M RTADG----IEHEVDCIVFATGFDVCKRGTPFPILGRDGRKLEDAWS-EG
Mflv_4608|M.gilvum_PYR-GCK RTADG----IEHELDCIVFATGFDVCKAGTPFPIRGAHGRELSDEWS-QG
MAV_1795|M.avium_104 RTSDG----IEHHLDCIVFATGYDVHLTGPPFPVTGLGGRSLAAEWA-GG
Mvan_1519|M.vanbaalenii_PYR-1 RTSDG----VEHHLDAIVFATGYDVHLSGPPFPVAGLNGRSLQQEWA-GH
MLBr_00065|M.leprae_Br4923 RLKSG----NELRADIIVTATGLNLQLFGGAVATVDGQPVDLAQTMS---
.* * :* *** .: . . .:
Mb3075c|M.bovis_AF2122/97 IGAHRGITVANMPNLFFLLGPNTG---LGHNSVVFMIESQIHYVADAIAK
Rv3049c|M.tuberculosis_H37Rv IGAHRGITVANMPNLFFLLGPNTG---LGHNSVVFMIESQIHYVADAIAK
MUL_1880|M.ulcerans_Agy99 IGAHRGIAVADVPNLFFLLGPNTG---LGHNSVVFMIESQIHYVADAIAK
TH_4080|M.thermoresistible__bu PMAHRGTAVADLPNAYLLLGPNTG---LGHNSMVYMIESQINYVIEAIKA
MSMEG_2310|M.smegmatis_MC2_155 IQAHRGVAVAGMPNLFFLLGPNTA---LGHNSVVFMIEQQIRYVGQAIAA
MAB_2073|M.abscessus_ATCC_1997 RYAFKSVSVAGYPNLFFTFGPNSG---PGHNSALVYMEAVIDYVVKAIKL
MMAR_3139|M.marinum_M RFAYKSVSVAGYPNLFFTFGPNSG---PGHNSALLYMEAAIDYIVKAIEL
Mflv_4608|M.gilvum_PYR-GCK AYAYRSVTVAGYPNLFFTFGPNSG---PGHNSALVYMEAEINYIVKAIGA
MAV_1795|M.avium_104 AQAYKSINVHGYPNLFVMTGPNSG---PGHNSLLVYIEGQLDYAVRGITT
Mvan_1519|M.vanbaalenii_PYR-1 AEAYKSASAHGYPNLFFMTGPNSG---PGHNSLLVYVEGQIAYAVDAITT
MLBr_00065|M.leprae_Br4923 ---YKGMMLSGLPNMIYTVGYTNASWTLKADLVSEFFCRLLNYMNANDFD
.:. . ** * ... : . : *
Mb3075c|M.bovis_AF2122/97 CDR--MGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGKN
Rv3049c|M.tuberculosis_H37Rv CDR--MGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGKN
MUL_1880|M.ulcerans_Agy99 CDK--RGAQALAPTRAAQDRFNEELQRRLAGSVWNSGGCSSWYLDEHGRN
TH_4080|M.thermoresistible__bu VDK--AGAQALAPTREAQDRYNAELQARLGRSVWNTGGCRSWYLDEHGNN
MSMEG_2310|M.smegmatis_MC2_155 VDK--AGAAALAPTRRAQDAFNAELQRDLSGTVFNTGGCKSWYLDEHGVN
MAB_2073|M.abscessus_ATCC_1997 LQQ--NDIGTLDVREDRQGRYHSEIQRRLRRTTWNSG-CSSWYLTEDGYN
MMAR_3139|M.marinum_M LRDQGNGVHTLDVKENSQNAYHSNIQRRLRRTTWNSG-CSSWYLTEDGYN
Mflv_4608|M.gilvum_PYR-GCK IIA--NDLSTLEVREDRQNNYHGEVQQRLGSTTWNSG-CKSWYLTNDGYN
MAV_1795|M.avium_104 ILN--DDLRYLDVREEVQRRHNEAIQRRLTKTTWMSG-CRSWYLTKDGFN
Mvan_1519|M.vanbaalenii_PYR-1 ILN--RNLRYLDVRADVQQRHNAQIQRRLTKTTWMSG-CHSWYLTADGFN
MLBr_00065|M.leprae_Br4923 TVA--VEYPGSDVEERPFMDFTPGYVLRSLDALPKQGSRTPWRLNQNYLR
. : * .* * . .
Mb3075c|M.bovis_AF2122/97 TVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN-------
Rv3049c|M.tuberculosis_H37Rv TVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN-------
MUL_1880|M.ulcerans_Agy99 TVLWCGYTWQYWLATRSVKPEEYQFFKAG-----AKSSVNG---------
TH_4080|M.thermoresistible__bu RVLWGGFTWQYRLATRTLDPAEYRFWG-----------------------
MSMEG_2310|M.smegmatis_MC2_155 RTLWSGMTWQYWKALRRLDPSEFEFLDQR---VLARS-------------
MAB_2073|M.abscessus_ATCC_1997 GTMYPGFATQFMRELSRLDPRDYVIT---RRDDAH-----------LRLT
MMAR_3139|M.marinum_M GTMYPGFATQFTRELSRLDMRDYDIT---RRDDAD-----------LKLT
Mflv_4608|M.gilvum_PYR-GCK GTMYPGFATQFKRALSKVDMGDYVTTPTTARTEHHPTEHAQNGSNVAKVA
MAV_1795|M.avium_104 GSMYPGFATQYLRQMSDFRYQDYQAVARRARTPAASSA------------
Mvan_1519|M.vanbaalenii_PYR-1 ASMYPGFATQYRRQM-QFRAEDYTAVA-----------------------
MLBr_00065|M.leprae_Br4923 DIRLIRRGKVADEGLLFAKKTTPVTV------------------------
Mb3075c|M.bovis_AF2122/97 ------------------------------------------------
Rv3049c|M.tuberculosis_H37Rv ------------------------------------------------
MUL_1880|M.ulcerans_Agy99 ------------------------------------------------
TH_4080|M.thermoresistible__bu ------------------------------------------------
MSMEG_2310|M.smegmatis_MC2_155 ------------------------------------------------
MAB_2073|M.abscessus_ATCC_1997 Q-----------------------------------------------
MMAR_3139|M.marinum_M QTR---------------------------------------------
Mflv_4608|M.gilvum_PYR-GCK QGRKAKVAQGRKSAGALPTRSDVKADILDVGVGKVPPKRAASRVRKDA
MAV_1795|M.avium_104 ------------------------------------------------
Mvan_1519|M.vanbaalenii_PYR-1 ------------------------------------------------
MLBr_00065|M.leprae_Br4923 ------------------------------------------------