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M. abscessus ATCC 19977 MAB_2014c (-)

annotation: putative transcriptional regulator, ArsR
coordinates: 2013918 - 2014262
length: 114

TAVIDDDLWAAVGDPTRLRVFDLILTHGMATATTLSDRLPVTRQAVTKHLSVLDKAGLVHATTHGREKQY
RADAEQVARIAEQLTAVGAAWDRRLARIKLIAESLSSAQKAED*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2014c--100% (114)putative transcriptional regulator, ArsR
M. abscessus ATCC 19977MAB_3862-5e-0933.98% (103) ArsR family transcriptional regulator
M. abscessus ATCC 19977MAB_4139-8e-0930.61% (98) ArsR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0591-7e-1038.82% (85) ArsR family transcriptional regulator
M. gilvum PYR-GCKMflv_2031-9e-0935.90% (78) activator of Hsp90 ATPase 1 family protein
M. tuberculosis H37RvRv0576-7e-1038.82% (85) ArsR family transcriptional regulator
M. leprae Br4923-----
M. marinum MMMAR_2816-9e-1136.00% (100) ArsR-type repressor
M. avium 104MAV_2783-5e-1135.00% (100) ArsR family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_6762-2e-0933.02% (106) transcriptional regulator
M. thermoresistible (build 8)TH_3423-5e-1435.11% (94) PUTATIVE -
M. ulcerans Agy99MUL_2937-4e-1136.00% (100) ArsR-type repressor
M. vanbaalenii PYR-1Mvan_3039-1e-0936.73% (98) regulatory protein, ArsR

CLUSTAL 2.0.9 multiple sequence alignment


Mb0591|M.bovis_AF2122/97            -------------MLEVAAEPTRRRLLQLLAP-GERTVTQLASQFTVTRS
Rv0576|M.tuberculosis_H37Rv         -------------MLEVAAEPTRRRLLQLLAP-GERTVTQLASQFTVTRS
MAB_2014c|M.abscessus_ATCC_199      -MTAVIDDD----LWAAVGDPTRLRVFDLILTHGMATATTLSDRLPVTRQ
MSMEG_6762|M.smegmatis_MC2_155      MWVTVIDEDRADALFHALADRTRRDIMRRVLA-GEQSVSALASKYDVSFA
Mvan_3039|M.vanbaalenii_PYR-1       -MVIEHDEDRADALFHALADRTRRDIMRRVLA-GEHSVSALAAKYDMSFA
MMAR_2816|M.marinum_M               ---MCTPERICDRIFVALASPVRRKLLEILTGQP-LSAGELSDRFELSRP
MUL_2937|M.ulcerans_Agy99           ---MCTPERICDRIFVALASPVRRKLLEILTGRP-LSAGELSDRFELSRP
MAV_2783|M.avium_104                ---MVVVTGV-DRVFLALANPVRRELLQLLARHP-LSAGELSERFELSRP
Mflv_2031|M.gilvum_PYR-GCK          ----------MDEVFRALADPSRRRLLDNLNARNGQSLRELCAGLDMARQ
TH_3423|M.thermoresistible__bu      ----MTATDQLHPVFHALGDPNRMRLITRLCDAGPGSTSQVAQAVSVSRQ
                                                 :  . ..  *  ::  :      :   :.    ::  

Mb0591|M.bovis_AF2122/97            AISQHLGMLAEAGLVTARKQGRERYYRLDERGVLRLR-----ALMESFWS
Rv0576|M.tuberculosis_H37Rv         AISQHLGMLAEAGLVTARKQGRERYYRLDERGVLRLR-----ALMESFWS
MAB_2014c|M.abscessus_ATCC_199      AVTKHLSVLDKAGLVHATTHGREKQYRADAEQVARIA-----EQLT----
MSMEG_6762|M.smegmatis_MC2_155      AVQKHVAVLEKAGLLTKRRRGREQLASGDVATVRSVS-----QMLA----
Mvan_3039|M.vanbaalenii_PYR-1       AVQKHVAVLDKAGLITKRRSGREQLASGDVEAVRSVA-----SMLT----
MMAR_2816|M.marinum_M               AIAEHLKVLREAGLVSDEAQGRRRIYRLTAEPLAELG-EWLHP-------
MUL_2937|M.ulcerans_Agy99           AIAEHLKVLREAGLVSDEAQGRRRIYRLTAEPLAELG-EWLHP-------
MAV_2783|M.avium_104                AVAEHLKVLREAALVADERRGRQRIYHLTAEPLAELG-EWLHP-------
Mflv_2031|M.gilvum_PYR-GCK          SVSKHLKVLEDANLVSIVWQGREKLHYLNAEPINAIADRWINH-------
TH_3423|M.thermoresistible__bu      AATKHLLILEEAGLVRSDRRGRERIWRMQPEALDDAS-EYLDR-------
                                    :  :*: :* .* *:     **.:        :                 

Mb0591|M.bovis_AF2122/97            DELDRLVADAAHYPPSQGDCAMPFEKAVVVPLDPTSTFALITQPDRLRRW
Rv0576|M.tuberculosis_H37Rv         DELDRLVADAAHYPPSQGDCAMPFEKAVVVPLDPTSTFALITQPDRLRRW
MAB_2014c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6762|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3039|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_2816|M.marinum_M               --------------------------------------------------
MUL_2937|M.ulcerans_Agy99           --------------------------------------------------
MAV_2783|M.avium_104                --------------------------------------------------
Mflv_2031|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3423|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb0591|M.bovis_AF2122/97            MAVAARIELRTGGAYRWTVTPGHSAAGTVIDVDPGKRVVFTWGWEDHGDP
Rv0576|M.tuberculosis_H37Rv         MAVAARIELRTGGAYRWTVTPGHSAAGTVIDVDPGKRVVFTWGWEDHGDP
MAB_2014c|M.abscessus_ATCC_199      ------------------------AVGAAWDRRLAR--------------
MSMEG_6762|M.smegmatis_MC2_155      ------------------------ELEQIWRGRIAR--------------
Mvan_3039|M.vanbaalenii_PYR-1       ------------------------ELEQIWRGRVSR--------------
MMAR_2816|M.marinum_M               -------------------------FEKLWRDKLSA--------------
MUL_2937|M.ulcerans_Agy99           -------------------------FEKLWREKLSA--------------
MAV_2783|M.avium_104                -------------------------FEKFWRTRLRR--------------
Mflv_2031|M.gilvum_PYR-GCK          -------------------------YDRMRAQTLAD--------------
TH_3423|M.thermoresistible__bu      -------------------------LARRWDRALGR--------------
                                                                                      

Mb0591|M.bovis_AF2122/97            PPGGSTVTITLTPVDGGTEVRLVHDGLTAQQAARHAKGWNHFLDRLVVAG
Rv0576|M.tuberculosis_H37Rv         PPGGSTVTITLTPVDGGTEVRLVHDGLTAQQAARHAKGWNHFLDRLVVAG
MAB_2014c|M.abscessus_ATCC_199      -------------------IKLIAESLSSAQKAED---------------
MSMEG_6762|M.smegmatis_MC2_155      ----------------------IDQLISSEPLKED---------------
Mvan_3039|M.vanbaalenii_PYR-1       ----------------------IDELIATDPRTENHDQEE----------
MMAR_2816|M.marinum_M               ----------------------LAETAEEQQ-------------------
MUL_2937|M.ulcerans_Agy99           ----------------------LAEAAEEQQ-------------------
MAV_2783|M.avium_104                ----------------------LAEVAEELE-------------------
Mflv_2031|M.gilvum_PYR-GCK          ----------------------LKTALERNPMADNTHSAAADFVYTTYIR
TH_3423|M.thermoresistible__bu      ----------------------LRAFVEAPEQPDPGMSE-----------
                                                          :                           

Mb0591|M.bovis_AF2122/97            QHGDAGPDEWAAAPDPLDELSCAEATLAVLQHVLRGIGASDLTRQTPCTE
Rv0576|M.tuberculosis_H37Rv         QRGDAGPDEWAAAPDPLDELSCAEATLAVLQHVLRGIGASDLTRQTPCTE
MAB_2014c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6762|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3039|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_2816|M.marinum_M               --------------------------------------------------
MUL_2937|M.ulcerans_Agy99           --------------------------------------------------
MAV_2783|M.avium_104                --------------------------------------------------
Mflv_2031|M.gilvum_PYR-GCK          TTPERLWQAVTDPAFSERYMGHGLVSDWQVGSTFAWRDGDLSITSPEQVI
TH_3423|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb0591|M.bovis_AF2122/97            YDVSQLADHLLRSLAIIGAAAGAQLAPRDVDAPLETQVADAAQAVMEAWR
Rv0576|M.tuberculosis_H37Rv         YDVSQLADHLLRSLAIIGAAAGAQLAPRDVDAPLETQVADAAQAVMEAWR
MAB_2014c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6762|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3039|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_2816|M.marinum_M               --------------------------------------------------
MUL_2937|M.ulcerans_Agy99           --------------------------------------------------
MAV_2783|M.avium_104                --------------------------------------------------
Mflv_2031|M.gilvum_PYR-GCK          LECEPYRRLAFTFHTFTKDLTTVGLSEDVIERAAAEPRSQVVFDIESVED
TH_3423|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb0591|M.bovis_AF2122/97            RRGLAGTVELNSNQVPATVPVGILCLEFLVHAWDFAIATGSQVIASEPVS
Rv0576|M.tuberculosis_H37Rv         RRGLAGTVELNSNQVPATVPVGILCLEFLVHAWDFAIATGSQVIASEPVS
MAB_2014c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6762|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3039|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_2816|M.marinum_M               --------------------------------------------------
MUL_2937|M.ulcerans_Agy99           --------------------------------------------------
MAV_2783|M.avium_104                --------------------------------------------------
Mflv_2031|M.gilvum_PYR-GCK          GRVKLTVTHTGFPSESIVRELVSGGWPSKLSDLKTHLELDRVAVGA----
TH_3423|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb0591|M.bovis_AF2122/97            EYVLAVAGKVITPATRNSAGFAAPAAVGSFAPVLDRLIAFTGRQPTAGHV
Rv0576|M.tuberculosis_H37Rv         EYVLAVAGKVITPATRNSAGFAAPAAVGSFAPVLDRLIAFTGRQPTAGHV
MAB_2014c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_6762|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3039|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_2816|M.marinum_M               --------------------------------------------------
MUL_2937|M.ulcerans_Agy99           --------------------------------------------------
MAV_2783|M.avium_104                --------------------------------------------------
Mflv_2031|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3423|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb0591|M.bovis_AF2122/97            SAT
Rv0576|M.tuberculosis_H37Rv         SAT
MAB_2014c|M.abscessus_ATCC_199      ---
MSMEG_6762|M.smegmatis_MC2_155      ---
Mvan_3039|M.vanbaalenii_PYR-1       ---
MMAR_2816|M.marinum_M               ---
MUL_2937|M.ulcerans_Agy99           ---
MAV_2783|M.avium_104                ---
Mflv_2031|M.gilvum_PYR-GCK          ---
TH_3423|M.thermoresistible__bu      ---