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MADGGDARRERWARHKVRVRRRFVAAAVVSIERKGPSATVEDVVRAAHSAKPKLYRHFDDRDDLFDSVAQ AMVAAIRRRLSGAVDMDMPPRKSAQRAASGIVALVQRFPQSTRFLFEHQMVGVRGKPAPALRPDGAIPEL AGAISSFLERVNVHPSGADQLAAALIGTAATTAIWHVAQSGEPDESADRRLAETLWACVDVFLRSKGVIV DPDRALDADRVRTARAALVDLRGEGQSPSFL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1536 | - | - | 100% (241) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4026c | - | 7e-19 | 28.57% (217) | transcriptional regulatory protein TetR |
| M. abscessus ATCC 19977 | MAB_4546c | - | 2e-10 | 27.85% (219) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3076c | - | 7e-17 | 27.15% (221) | AsnC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4290 | - | 2e-19 | 27.51% (229) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3050c | - | 7e-17 | 27.15% (221) | AsnC family transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 6e-18 | 25.76% (229) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_1643 | - | 5e-17 | 24.89% (225) | AsnC family transcriptional regulator |
| M. avium 104 | MAV_3917 | - | 9e-19 | 25.45% (224) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2309 | - | 2e-19 | 26.64% (229) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1826 | - | 9e-20 | 26.82% (220) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1879 | - | 4e-17 | 24.89% (225) | AsnC family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2056 | - | 2e-17 | 26.51% (215) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1643|M.marinum_M -----------------------------MRRISRPHPNADAGVKVDARS
MUL_1879|M.ulcerans_Agy99 -----------------------------MRRISRAHLNADAGVKVDARS
Mb3076c|M.bovis_AF2122/97 -----------------------------MVRIPRPHPSAKPGVKVDARS
Rv3050c|M.tuberculosis_H37Rv -----------------------------MVRIPRPHPSAKPGVKVDARS
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
MAV_3917|M.avium_104 --------------------------MVRMPRPARPHSATKPGAKVDARS
Mflv_4290|M.gilvum_PYR-GCK -----------------------------MRRGSRARAAEETGVKVDARS
Mvan_2056|M.vanbaalenii_PYR-1 ----------------------MAGYSDRVRRGSRARAAEEPGVKVDARS
MSMEG_2309|M.smegmatis_MC2_155 -----------------------------MRRGSRSHSGG-PGVKVDARS
TH_1826|M.thermoresistible__bu ---------------------------------------------VDARS
MAB_1536|M.abscessus_ATCC_1997 -----------------------------------------MADGGDARR
***
MMAR_1643|M.marinum_M ERWREHRKKVRNEIVEAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFT
MUL_1879|M.ulcerans_Agy99 ERWREHRKKVRNEIVEAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFT
Mb3076c|M.bovis_AF2122/97 ERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAGTAKPKIYRHFT
Rv3050c|M.tuberculosis_H37Rv ERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAGTAKPKIYRHFT
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLGPEVSVREIAEEAGTAKPKIYRHFT
MAV_3917|M.avium_104 ERWREHRKKVRNEIVDAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFH
Mflv_4290|M.gilvum_PYR-GCK ERWREHRKKVRSEIVDAAFRAIDRLGPEVSLREIAEEAGTAKPKIYRHFT
Mvan_2056|M.vanbaalenii_PYR-1 ERWREHRKKVRSEIVDAAFRAIDRLGPEVSLREIAEEAGTAKPKIYRHFT
MSMEG_2309|M.smegmatis_MC2_155 ERWREHRKKVRSEIVDAAFRAIDRLGPELSLREIAEEAGTAKPKIYRHFT
TH_1826|M.thermoresistible__bu ERWREHRKKVRAEIVDAAYRAIDRLGPELSLREIAAEAGTAKPKIYRHFT
MAB_1536|M.abscessus_ATCC_1997 ERWARHKVRVRRRFVAAAVVSIERKGPSATVEDVVRAAHSAKPKLYRHFD
*** .*: :** .:* ** :::* **. ::.::. * :****:****
MMAR_1643|M.marinum_M DKSDLFVAIGERLRDMLWTSIFPSINLATDSAREVIRRSVEEYVSLVDKH
MUL_1879|M.ulcerans_Agy99 DKSDLFVAIRERLRDMLWTSIFPSINLATDSAREVIRRSVEEYVSLVDKH
Mb3076c|M.bovis_AF2122/97 DKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQH
Rv3050c|M.tuberculosis_H37Rv DKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQH
MLBr_01733|M.leprae_Br4923 DKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDKH
MAV_3917|M.avium_104 DKSDLFQAIGERLRDMLWTAIFPSIDLKTDSAREVIRRSVEEYVTLVDKH
Mflv_4290|M.gilvum_PYR-GCK DKADLFQAIGQRMRDMLWAAIFPSIDISTDPARTVVFRAVEQYVRLVDEH
Mvan_2056|M.vanbaalenii_PYR-1 DKSDLFQAIGQRMRDMLWAAIFPSINISTDAARTVVFRAVEQYVRLVDEH
MSMEG_2309|M.smegmatis_MC2_155 DKSDLFQAIGERLRDMLWSAIFPSINLASDPAREVIRRSVEQYVRLVDEH
TH_1826|M.thermoresistible__bu DKADLHQAIGQRLRDMLWAAIFPSIDLSADSGREIIRRSVEQYVRLVDQH
MAB_1536|M.abscessus_ATCC_1997 DRDDLFDSVAQAMVAAIRRRLSGAVDMDMPP-RKSAQRAASGIVALVQRF
*: ** :: : : : :::: . * *:.. * **:..
MMAR_1643|M.marinum_M PNVLRVFIQGRFATQSEATVRTLNEGREITLTFAEMFNNELREMELNRAA
MUL_1879|M.ulcerans_Agy99 PNVLRVFIQGRFATQSEATVRTLNEGREITLTFAEMFNNELREMELNRAA
Mb3076c|M.bovis_AF2122/97 PNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNNELREMELNRAA
Rv3050c|M.tuberculosis_H37Rv PNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNNELREMELNRAA
MLBr_01733|M.leprae_Br4923 PNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELNRAA
MAV_3917|M.avium_104 PNVLRVFIQGRSTGTPQSTVTILNEGREITLAMADLFDNELREMELDHAA
Mflv_4290|M.gilvum_PYR-GCK PNVVRFLMQGRFAEQTESAMRALNEGRDITLAMADMFNNELKDMQLDYAA
Mvan_2056|M.vanbaalenii_PYR-1 PNVVRFLMQGRFAEQSESAMRALNEGRDITLGIAEMFNNELSDMELDNAA
MSMEG_2309|M.smegmatis_MC2_155 PNVLRFLIQGRFAEQSESTMRALNEGRGITLAMADMFSHELREMELDGAA
TH_1826|M.thermoresistible__bu PNVLRFLLQGRFADQSASAARALNEGRDITLAMADMFDNELREIELDPTA
MAB_1536|M.abscessus_ATCC_1997 PQSTRFLFEHQMVGVRGKPAPALRPDGAIP-ELAGAISSFLERVNVHPSG
*: *.::: : . * . *. :* :. * :::. :.
MMAR_1643|M.marinum_M FELAAFAAFGSAASATEWWLGPEPDSPRRMPHDQFVAHLTTIMMGVIVGT
MUL_1879|M.ulcerans_Agy99 FELAAFAAFGSAASATEWWLGPEPDSPRRMPHDQFVAHLTTIMMGVIVGT
Mb3076c|M.bovis_AF2122/97 LELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMMGVIVGT
Rv3050c|M.tuberculosis_H37Rv LELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMMGVIVGT
MLBr_01733|M.leprae_Br4923 SELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVGT
MAV_3917|M.avium_104 VELAAHAAFGSAASATEWWLGPEPDSPRLMSRAQFVAHLSTIMMAVIIGT
Mflv_4290|M.gilvum_PYR-GCK FELAGFATFGAAASATDWWLGAERDSPRRLPSEKFVDYLTKIMVGSINGT
Mvan_2056|M.vanbaalenii_PYR-1 FELAGFATFGAAASATDWWLGAEQDSPRRLPSEKFVDYLTTIMVGSINGT
MSMEG_2309|M.smegmatis_MC2_155 IELAAFATFGAAASATDWWLGSKEDSPRRMPADEFVNHLTTIMVGSINGT
TH_1826|M.thermoresistible__bu LELAAHAAFGSIASATDWWLGAETDSPRRMPSDQFIAHLTTITVGAINGT
MAB_1536|M.abscessus_ATCC_1997 ADQLAAALIGTAATTAIWHVAQSGE-----PDESADRRLAETLWACVDVF
: . * :*: *::: * :. . : . . *: . :
MMAR_1643|M.marinum_M AEALGIAMDPDKPIHDAVPAPTADRR-------------
MUL_1879|M.ulcerans_Agy99 AEALGIAMDPDKPIHDAVPAPTADRR-------------
Mb3076c|M.bovis_AF2122/97 AEALGIAVDPDQPIHDAVPNNPAVR--------------
Rv3050c|M.tuberculosis_H37Rv AEALGIAVDPDQPIHDAVPNNPAVR--------------
MLBr_01733|M.leprae_Br4923 AETLGISMNPDRPIHDAVPLDRSAS--------------
MAV_3917|M.avium_104 AETLGITMNPDQPIHDAVVRKPAVS--------------
Mflv_4290|M.gilvum_PYR-GCK CEVLGVKIDPDVPLHEGVTRREQVA--------------
Mvan_2056|M.vanbaalenii_PYR-1 CEVLGIKIDPDVPLHEGVKRREQVA--------------
MSMEG_2309|M.smegmatis_MC2_155 CELLGIRIDPDLPLHEGVQRRERAS--------------
TH_1826|M.thermoresistible__bu CEMLGIKIDPDLPLHAGVRRREDVA--------------
MAB_1536|M.abscessus_ATCC_1997 LRSKGVIVDPDRALDADRVRTARAALVDLRGEGQSPSFL
. *: ::** .:.