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M. gilvum PYR-GCK Mflv_4290 (-)

annotation: TetR family transcriptional regulator
coordinates: 4557633 - 4558373
length: 246

RRGSRARAAEETGVKVDARSERWREHRKKVRSEIVDAAFRAIDRLGPEVSLREIAEEAGTAKPKIYRHFT
DKADLFQAIGQRMRDMLWAAIFPSIDISTDPARTVVFRAVEQYVRLVDEHPNVVRFLMQGRFAEQTESAM
RALNEGRDITLAMADMFNNELKDMQLDYAAFELAGFATFGAAASATDWWLGAERDSPRRLPSEKFVDYLT
KIMVGSINGTCEVLGVKIDPDVPLHEGVTRREQVA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4290--100% (246)TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0103-8e-2130.32% (221) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_4602-1e-1831.31% (214) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3076c-1e-9668.16% (245) AsnC family transcriptional regulator
M. tuberculosis H37RvRv3050c-1e-9668.16% (245) AsnC family transcriptional regulator
M. leprae Br4923MLBr_01733-3e-9366.95% (239) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_2968-3e-4640.28% (216) TetR family transcriptional regulator
M. marinum MMMAR_1643-2e-9669.46% (239) AsnC family transcriptional regulator
M. avium 104MAV_3917-5e-9165.16% (244) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_2309-1e-11379.27% (246) transcriptional regulatory protein
M. thermoresistible (build 8)TH_1826-1e-10477.83% (230) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_1879-3e-9669.46% (239) AsnC family transcriptional regulator
M. vanbaalenii PYR-1Mvan_2056-1e-13193.90% (246) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4290|M.gilvum_PYR-GCK          -----------------------------MRRGSRARAAEETGVKVDARS
Mvan_2056|M.vanbaalenii_PYR-1       ----------------------MAGYSDRVRRGSRARAAEEPGVKVDARS
MSMEG_2309|M.smegmatis_MC2_155      -----------------------------MRRGSRSHSGG-PGVKVDARS
TH_1826|M.thermoresistible__bu      ---------------------------------------------VDARS
MMAR_1643|M.marinum_M               -----------------------------MRRISRPHPNADAGVKVDARS
MUL_1879|M.ulcerans_Agy99           -----------------------------MRRISRAHLNADAGVKVDARS
Mb3076c|M.bovis_AF2122/97           -----------------------------MVRIPRPHPSAKPGVKVDARS
Rv3050c|M.tuberculosis_H37Rv        -----------------------------MVRIPRPHPSAKPGVKVDARS
MLBr_01733|M.leprae_Br4923          MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
MAV_3917|M.avium_104                --------------------------MVRMPRPARPHSATKPGAKVDARS
MAB_2968|M.abscessus_ATCC_1997      -------------------------------------MSTAIASKAAPVA
                                                                                   . :

Mflv_4290|M.gilvum_PYR-GCK          ERWREHRKKVRSEIVDAAFRAIDRLGPEVSLREIAEEAGTAKPKIYRHFT
Mvan_2056|M.vanbaalenii_PYR-1       ERWREHRKKVRSEIVDAAFRAIDRLGPEVSLREIAEEAGTAKPKIYRHFT
MSMEG_2309|M.smegmatis_MC2_155      ERWREHRKKVRSEIVDAAFRAIDRLGPELSLREIAEEAGTAKPKIYRHFT
TH_1826|M.thermoresistible__bu      ERWREHRKKVRAEIVDAAYRAIDRLGPELSLREIAAEAGTAKPKIYRHFT
MMAR_1643|M.marinum_M               ERWREHRKKVRNEIVEAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFT
MUL_1879|M.ulcerans_Agy99           ERWREHRKKVRNEIVEAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFT
Mb3076c|M.bovis_AF2122/97           ERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAGTAKPKIYRHFT
Rv3050c|M.tuberculosis_H37Rv        ERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAGTAKPKIYRHFT
MLBr_01733|M.leprae_Br4923          ERWREHRKKVRGEIVDAAFRALDRLGPEVSVREIAEEAGTAKPKIYRHFT
MAV_3917|M.avium_104                ERWREHRKKVRNEIVDAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFH
MAB_2968|M.abscessus_ATCC_1997      ARRGDRRKVAREELLDAAFRAIDGLGATVSMDDIAREAGVAKPKLYRYFE
                                     *  ::** .* *:::**:**:* **. :*: :** ***.****:**:* 

Mflv_4290|M.gilvum_PYR-GCK          DKADLFQAIGQRMRDMLWAAIFPSIDISTDPARTVVFRAVEQYVRLVDEH
Mvan_2056|M.vanbaalenii_PYR-1       DKSDLFQAIGQRMRDMLWAAIFPSINISTDAARTVVFRAVEQYVRLVDEH
MSMEG_2309|M.smegmatis_MC2_155      DKSDLFQAIGERLRDMLWSAIFPSINLASDPAREVIRRSVEQYVRLVDEH
TH_1826|M.thermoresistible__bu      DKADLHQAIGQRLRDMLWAAIFPSIDLSADSGREIIRRSVEQYVRLVDQH
MMAR_1643|M.marinum_M               DKSDLFVAIGERLRDMLWTSIFPSINLATDSAREVIRRSVEEYVSLVDKH
MUL_1879|M.ulcerans_Agy99           DKSDLFVAIRERLRDMLWTSIFPSINLATDSAREVIRRSVEEYVSLVDKH
Mb3076c|M.bovis_AF2122/97           DKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQH
Rv3050c|M.tuberculosis_H37Rv        DKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQH
MLBr_01733|M.leprae_Br4923          DKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDKH
MAV_3917|M.avium_104                DKSDLFQAIGERLRDMLWTAIFPSIDLKTDSAREVIRRSVEEYVTLVDKH
MAB_2968|M.abscessus_ATCC_1997      DKADLHSAVLERVQDMLWSASMDRINLMTDSARDLVEHGANEYAQMISDH
                                    **:**  *:  *::****:: :  ::: :*..* :: :..::*. ::..*

Mflv_4290|M.gilvum_PYR-GCK          PNVVRFLMQGRFAEQTESAMRALNEGRDITLAMADMFNNELKDMQLDYAA
Mvan_2056|M.vanbaalenii_PYR-1       PNVVRFLMQGRFAEQSESAMRALNEGRDITLGIAEMFNNELSDMELDNAA
MSMEG_2309|M.smegmatis_MC2_155      PNVLRFLIQGRFAEQSESTMRALNEGRGITLAMADMFSHELREMELDGAA
TH_1826|M.thermoresistible__bu      PNVLRFLLQGRFADQSASAARALNEGRDITLAMADMFDNELREIELDPTA
MMAR_1643|M.marinum_M               PNVLRVFIQGRFATQSEATVRTLNEGREITLTFAEMFNNELREMELNRAA
MUL_1879|M.ulcerans_Agy99           PNVLRVFIQGRFATQSEATVRTLNEGREITLTFAEMFNNELREMELNRAA
Mb3076c|M.bovis_AF2122/97           PNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNNELREMELNRAA
Rv3050c|M.tuberculosis_H37Rv        PNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNNELREMELNRAA
MLBr_01733|M.leprae_Br4923          PNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELNRAA
MAV_3917|M.avium_104                PNVLRVFIQGRSTGTPQSTVTILNEGREITLAMADLFDNELREMELDHAA
MAB_2968|M.abscessus_ATCC_1997      PNVLRFIVHGHFINSSDGTERLVETAQQMTHDIAEILSSAIDDETVDIDD
                                    ***:*.:::*:    . .:   :: .: :*  :*:::.  : :  ::   

Mflv_4290|M.gilvum_PYR-GCK          FELAGFATFGAAASATDWWLGAERDSPRRLPSEKFVDYLTKIMVGSINGT
Mvan_2056|M.vanbaalenii_PYR-1       FELAGFATFGAAASATDWWLGAEQDSPRRLPSEKFVDYLTTIMVGSINGT
MSMEG_2309|M.smegmatis_MC2_155      IELAAFATFGAAASATDWWLGSKEDSPRRMPADEFVNHLTTIMVGSINGT
TH_1826|M.thermoresistible__bu      LELAAHAAFGSIASATDWWLGAETDSPRRMPSDQFIAHLTTITVGAINGT
MMAR_1643|M.marinum_M               FELAAFAAFGSAASATEWWLGPEPDSPRRMPHDQFVAHLTTIMMGVIVGT
MUL_1879|M.ulcerans_Agy99           FELAAFAAFGSAASATEWWLGPEPDSPRRMPHDQFVAHLTTIMMGVIVGT
Mb3076c|M.bovis_AF2122/97           LELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMMGVIVGT
Rv3050c|M.tuberculosis_H37Rv        LELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMMGVIVGT
MLBr_01733|M.leprae_Br4923          SELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVGT
MAV_3917|M.avium_104                VELAAHAAFGSAASATEWWLGPEPDSPRLMSRAQFVAHLSTIMMAVIIGT
MAB_2968|M.abscessus_ATCC_1997      ADLAVSSAAGAIGTATEWFLGPNQLRADPMPIERFVEYLTTVLSGLAASI
                                     :**  :: *: .:**:*:**.:   .  :.  .*: :*: :  .   . 

Mflv_4290|M.gilvum_PYR-GCK          CEVLGVKIDPDVPLHEGVTRREQVA-
Mvan_2056|M.vanbaalenii_PYR-1       CEVLGIKIDPDVPLHEGVKRREQVA-
MSMEG_2309|M.smegmatis_MC2_155      CELLGIRIDPDLPLHEGVQRRERAS-
TH_1826|M.thermoresistible__bu      CEMLGIKIDPDLPLHAGVRRREDVA-
MMAR_1643|M.marinum_M               AEALGIAMDPDKPIHDAVPAPTADRR
MUL_1879|M.ulcerans_Agy99           AEALGIAMDPDKPIHDAVPAPTADRR
Mb3076c|M.bovis_AF2122/97           AEALGIAVDPDQPIHDAVPNNPAVR-
Rv3050c|M.tuberculosis_H37Rv        AEALGIAVDPDQPIHDAVPNNPAVR-
MLBr_01733|M.leprae_Br4923          AETLGISMNPDRPIHDAVPLDRSAS-
MAV_3917|M.avium_104                AETLGITMNPDQPIHDAVVRKPAVS-
MAB_2968|M.abscessus_ATCC_1997      AEFNGLTLDPDQPLHLAFTRIQGGAS
                                    .*  *: ::** *:* ..