For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SDTTAHSGLDGLDTPFLAVDLAVMDRNIERLAGRLRGTGIRLRPHAKSHKCIEIARRQIDSGAIGLTVAT VGEAEVFAEAGFIDLFIAYPLWVTAQKARRLRQVASRAALRVAVDSAAGAQQLAEHLGDLPITVVIEVDS GHHRTGVAPDQAGPVAAAARSAGLNVVGIFTFPGHGYTPGHRAEVAAQESHALDTAAASLRAQGIDPSVR SGGSTPTVGAADDTVLTEVRPGVYPFNDAQQLELDVCTLDDIALSAVTTVVHARGRTAVVDAGSKILGAD RPGWATGFGRVIDEPDARIVALSEHHATIEFPGAAPPPGTRLRVAPNHLCNAVNLVDSLVIDAADGVRHW AVAARGANT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1253c | - | - | 100% (360) | hypothetical protein MAB_1253c |
| M. abscessus ATCC 19977 | MAB_0106c | - | 1e-08 | 24.92% (333) | hypothetical protein MAB_0106c |
| M. abscessus ATCC 19977 | MAB_3885 | - | 2e-06 | 32.70% (159) | hypothetical protein MAB_3885 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1448 | - | 3e-37 | 50.30% (167) | hypothetical protein Mb1448 |
| M. gilvum PYR-GCK | Mflv_1427 | - | 2e-11 | 25.61% (367) | hypothetical protein Mflv_1427 |
| M. tuberculosis H37Rv | Rv1413 | - | 3e-37 | 50.30% (167) | hypothetical protein Rv1413 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2646 | - | 9e-08 | 28.73% (181) | hypothetical protein MMAR_2646 |
| M. avium 104 | MAV_4372 | alr | 2e-07 | 24.22% (223) | alanine racemase |
| M. smegmatis MC2 155 | MSMEG_3786 | - | 3e-10 | 24.70% (332) | D-amino acid deaminase |
| M. thermoresistible (build 8) | TH_1694 | - | 1e-05 | 27.38% (168) | ALANINE RACEMASE ALR |
| M. ulcerans Agy99 | MUL_3122 | - | 2e-07 | 26.82% (179) | hypothetical protein MUL_3122 |
| M. vanbaalenii PYR-1 | Mvan_5361 | - | 4e-16 | 26.21% (351) | hypothetical protein Mvan_5361 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1448|M.bovis_AF2122/97 --------------------------------------------------
Rv1413|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1253c|M.abscessus_ATCC_199 --------------------------------------------MSDTTA
MMAR_2646|M.marinum_M -------------------------MHEVGREQRSDEMARLDEQNRLQRY
MUL_3122|M.ulcerans_Agy99 -------------------------MHEVGREQRSDEMARLDEQNRLQRY
Mflv_1427|M.gilvum_PYR-GCK MTAPGIAPIDDAVFDAAVRDLHDRPLDWRFKGVPADWWGRTEAQIIAAGS
Mvan_5361|M.vanbaalenii_PYR-1 MTVPVNAPIDMAVYRTGVRALSDQPLDWSFKGIPARWWGRTPAQIVAQRP
MSMEG_3786|M.smegmatis_MC2_155 ------------MRTTTTRAEHLSELD---KALPSEADGLSVQEFLATRP
MAV_4372|M.avium_104 ---------------------------------------------MAVTP
TH_1694|M.thermoresistible__bu -----------------------------------------MGSDTTGHP
Mb1448|M.bovis_AF2122/97 --------------------------------------------------
Rv1413|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1253c|M.abscessus_ATCC_199 HSGLDGLDTPFLAVDLAVMDRNIERLAGRLRGTGIRLRPHAK--SHKCIE
MMAR_2646|M.marinum_M EEAFADQDAPFAFVDLDAMWSNAGQMLSRAGDKPIRVASKSL--RCRPLQ
MUL_3122|M.ulcerans_Agy99 EEAFADQDAPFAFVDLDAMWSNAGQMLSRAGDKPIRVASKSL--RCRPLQ
Mflv_1427|M.gilvum_PYR-GCK AVPVGVGAGPHCVLRADALTHNLHTMARWCAARGMELAPHGK--THMSPQ
Mvan_5361|M.vanbaalenii_PYR-1 ELFGAGAIGPVCVLRDEALTHNLQTMAGWCRDRGVELAPHGK--THMSPQ
MSMEG_3786|M.smegmatis_MC2_155 RLSS--FSTPVLTLDDSAIDQNLSAMAAWCADNGIDLAPHGK--TTMSPT
MAV_4372|M.avium_104 ISLTPG-VLAEALVDLGAIEHNVRLLCEQARGAQVMAVVKADGYGHGAVQ
TH_1694|M.thermoresistible__bu AQRTVSSATAEAVVDLGAIAHNVRVVRERAGSAQVMAVVKADGYGHGATA
Mb1448|M.bovis_AF2122/97 --------------MATIGEVEVFVDHGADDVFITYPLWIGTRQADRLRQ
Rv1413|M.tuberculosis_H37Rv --------------MATIGEVEVFVDHGADDVFITYPLWIGTRQADRLRQ
MAB_1253c|M.abscessus_ATCC_199 IARRQIDSGAIGLTVATVGEAEVFAEAGFIDLFIAYPLWVTAQKARRLRQ
MMAR_2646|M.marinum_M REILDSNPRFEGLMTFTLAETLWLAGQGFDNLLLAYPTTDRTG-LRELGE
MUL_3122|M.ulcerans_Agy99 REILDSNPRFEGLMTFTLAETLWLAGQGFDNLLLAYPTTDRTG-LRALGE
Mflv_1427|M.gilvum_PYR-GCK LAERQLAGGACAITVATVAQAAVYRAFGVRSLLLANELVDAAG-LRWVSA
Mvan_5361|M.vanbaalenii_PYR-1 LAARQLAAGACAVTVATIGQAAVYRAFGVRSLVLANELVDGAG-LRWLAA
MSMEG_3786|M.smegmatis_MC2_155 LWERQLRAGATAITLATFSQVRVAVHFGVRRILLANALVDPGA-LRWLVQ
MAV_4372|M.avium_104 TARAALAAGAAELGVATVDEALALRAAGISAPVLAWLHPPGIDFRPALLA
TH_1694|M.thermoresistible__bu VARTALAAGATELGVATVGEALALRRDGVTAPVLSWLNPPGTDYAPALRA
*. :. * .:: :
Mb1448|M.bovis_AF2122/97 LADRARIAVGAGTAEGASNTGARLADAAG-----AIDVLIEIDSGHHRSG
Rv1413|M.tuberculosis_H37Rv LADRARIAVGAGTAEGASNTGARLADAAG-----AIDVLIEIDSGHHRSG
MAB_1253c|M.abscessus_ATCC_199 VASRAALRVAVDSAAGAQQLAEHLGDLP-------ITVVIEVDSGHHRTG
MMAR_2646|M.marinum_M LTAENPARAPIVMVDSVEHLDLIDRATDR-----PVRLCLDLDAGYWRAG
MUL_3122|M.ulcerans_Agy99 LTAENPARAPIAMVDSVEHLDLIDRATDR-----PVRLCLDLDAGYWRAG
Mflv_1427|M.gilvum_PYR-GCK ELDRDPDLRFVCWVDSVRGVELMTAALDG--ARRPIDVCVEVGIPGGRFG
Mvan_5361|M.vanbaalenii_PYR-1 ELDRDPGLRFVCWVDSVRGVELMSDALAG--ARRRVDVCVEVGMPHGRTG
MSMEG_3786|M.smegmatis_MC2_155 HMTDDPELHVVAWADSTATVDAMTAALADVPVAQPVPVLVELGASGGRTG
MAV_4372|M.avium_104 GVQIG--------LSSQRQLDELLTAVRD--TGRTATVTVKVDTGLNRNG
TH_1694|M.thermoresistible__bu QIEVA--------VSSRRQLDEVLDAARR--TGVTATLSVKVDTGLNRNG
. : :.:. * *
Mb1448|M.bovis_AF2122/97 ------------VRAEQVLEVAHAVG-EAGLHLVGVFTFPGHSYAPGKPG
Rv1413|M.tuberculosis_H37Rv ------------VRAEQVLEVAHAVG-EAGLHLVGVFTFPGHSYAPGKPG
MAB_1253c|M.abscessus_ATCC_199 ------------VAPDQAGPVAAAAR-SAGLNVVGIFTFPGHGYTPGHRA
MMAR_2646|M.marinum_M GRVKVGPKRSPLHTPEQARELALEIARRPRLRLVALMSYEGHIAGFGDQV
MUL_3122|M.ulcerans_Agy99 GRVKVGPKRSPLHTPERARELALEIARRPRLRLVALMSYEGHIAGFGDQV
Mflv_1427|M.gilvum_PYR-GCK -----------CRTAEAADDVARAAAASPRLRLVGVAGYEAAVAQSLDDD
Mvan_5361|M.vanbaalenii_PYR-1 -----------CRSEADTDEVARAVVNSPRLRLVGVAGYEAALSQTLTAE
MSMEG_3786|M.smegmatis_MC2_155 -----------ARSVDDAMVVAERIAACGVLRLAGVAGYEGALAHDASEP
MAV_4372|M.avium_104 ---------VPPAQYPSMLTALRRAVAEQAIVPRGLMSHMVYADQPANPV
TH_1694|M.thermoresistible__bu ---------VSRAEYPEVLAAVRRAQAEGAIRLRAVMSHLVAADEPDNPV
: .: .
Mb1448|M.bovis_AF2122/97 E---------------AGEQERRALNDAANALVAVGFPISCRSGGSTPTA
Rv1413|M.tuberculosis_H37Rv E---------------AGEQERRALNDAANALVAVGFPISCRSGGSTPTA
MAB_1253c|M.abscessus_ATCC_199 E---------------VAAQESHALDTAAASLRAQGIDPSVRSGGSTPTV
MMAR_2646|M.marinum_M AGKFAQNAIVRWMQRESFAELRERRARAVELVSEVAELEIVNAGGTGDLQ
MUL_3122|M.ulcerans_Agy99 AGKFAQNAIVRWMQRESFAELRERRARAVELVSEVAELKIVNAGGTGDLQ
Mflv_1427|M.gilvum_PYR-GCK ALAVVTAHLAEVR--ATVIRLAALFE-DDDVVVTAGGSTYFDAVADALSD
Mvan_5361|M.vanbaalenii_PYR-1 AVAAVTAHLAQLR--ATVIRLSALFE-TDDVLVTAGGSTYFDDVAEALTG
MSMEG_3786|M.smegmatis_MC2_155 SLARVRAYLQEMARLHRTITDRGLYDPTIDVIVTAGGSAYFDVVAEVLAP
MAV_4372|M.avium_104 NDVQAQ----RFTDMLAQAREQGVRFEVAHLSNSSATMSRPDLAFDMVRP
TH_1694|M.thermoresistible__bu TDIQRQ----RFSEMRAQARDAGLRFEIAHLCNSAGTMSRPDLAFDMVRA
.
Mb1448|M.bovis_AF2122/97 ---------LLTAADG----------------------ASETSRRLCAR-
Rv1413|M.tuberculosis_H37Rv ---------LLTAADG----------------------ASETSRRLCAR-
MAB_1253c|M.abscessus_ATCC_199 GAA---DDTVLTEVRPGVYPFNDAQQLELDVCTLDDIALSAVTTVVHARG
MMAR_2646|M.marinum_M LVA---HESAVTEATAG--SGFYAPTLFDSYSAFSLQPAAMFALPICRRP
MUL_3122|M.ulcerans_Agy99 LVA---HESAVTEATAG--SGFYAPTLFDSYSAFSLQPAAMFALPICRRP
Mflv_1427|M.gilvum_PYR-GCK WPG---GARVRPILRSGCYLAHDHGLYARTSPLTRG-RPDGFRPALEIRA
Mvan_5361|M.vanbaalenii_PYR-1 WPSGLSGLSVRTVLRSGCYLTHDHGLYANTSPLTRG-GRTGLRPALEVHA
MSMEG_3786|M.smegmatis_MC2_155 LAG----PRVRVVVRAGAYVIHDDGFYTGITPFGRTPGGYRLRSAMHAWA
MAV_4372|M.avium_104 GIA---VYGLSPVPELGDMGLVPAMTVKCTVALVKSIRAGESVSYGHTWT
TH_1694|M.thermoresistible__bu GIA---VYGLSPIPQRGDLGLKPAMTLKCPVALVKQVRAGEGVSYGHAWT
Mb1448|M.bovis_AF2122/97 --------------------------------------------------
Rv1413|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1253c|M.abscessus_ATCC_199 RTAVVDAGSKILGADR---PGWATGFGRVIDEPDAR--------IVALS-
MMAR_2646|M.marinum_M GAKTVTALGGGYLASG---VGAKDRMPSPYLPSGLK--------LDPMEG
MUL_3122|M.ulcerans_Agy99 GAKTVTALGGGYLASG---VGAKDRMPSPYLPSGLK--------LDPLEG
Mflv_1427|M.gilvum_PYR-GCK QVLSRPEPDLAIVGMGRRDVSFDQGMPVPLDDAAGA-----------VEK
Mvan_5361|M.vanbaalenii_PYR-1 QVVSRPEPDLAILTMGRRDVPFDQGLPVALAPAAGT-----------VTK
MSMEG_3786|M.smegmatis_MC2_155 RVVSRPEPELALLDAGKRDVPFDEGLPVPQLVAAQLGAPARPLTGTQITA
MAV_4372|M.avium_104 AQRDTNLALLPVGYADGIFRSLGGRLQVSINGRRRPGVGRICMDQFVVDL
TH_1694|M.thermoresistible__bu ADRDTTIALLPIGYADGVFRPLSNRFEVLINGRRHRNVGRVCMDQFVVDL
Mb1448|M.bovis_AF2122/97 --------------------------------------------------
Rv1413|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1253c|M.abscessus_ATCC_199 ---EHHATIEFPGAAPPPGTRLRVAPNHLCNAVNLVDSLVIDAADGVRHW
MMAR_2646|M.marinum_M TGEVQTPLSGRAARRLKVGDKVYFRHTKAGELCERFDRLYLVRGAQVVDV
MUL_3122|M.ulcerans_Agy99 TGEVQTPLSGRAARRLKVGDKVYFRHTKAGELCERFDRLYLVRGAQVVDV
Mflv_1427|M.gilvum_PYR-GCK LNDQHAYLRVTSG-DVEVGDWLRFGISHPCTTFDKWRLIPVLD---ADDR
Mvan_5361|M.vanbaalenii_PYR-1 LNDQHAYLELGPGGAAGVGQWLRFGISHPCTLFDKWRLLPVLD---ADDR
MSMEG_3786|M.smegmatis_MC2_155 VNDQHAFLALPADSDVKVGDVVRLGLSHPCTAFDKWRWIPLLNGNGDDPH
MAV_4372|M.avium_104 GPGRPDVAEGDEAILFGPGSNGEPTAQDWADLLGTIHYEVVTSPRGRITR
TH_1694|M.thermoresistible__bu GPGPVDVTEGDEAILFGPGDSGEPSAQDWADLLDTIHYEVVTSPRGRVVR
Mb1448|M.bovis_AF2122/97 -----------------------
Rv1413|M.tuberculosis_H37Rv -----------------------
MAB_1253c|M.abscessus_ATCC_199 AVAARGANT--------------
MMAR_2646|M.marinum_M VPTYRGEGRTFL-----------
MUL_3122|M.ulcerans_Agy99 VPTYRGEGRTFL-----------
Mflv_1427|M.gilvum_PYR-GCK VVDLVHTFF--------------
Mvan_5361|M.vanbaalenii_PYR-1 VVDLIRTFF--------------
MSMEG_3786|M.smegmatis_MC2_155 VVDMIRTYF--------------
MAV_4372|M.avium_104 TYREAHTVES-------------
TH_1694|M.thermoresistible__bu TYREADARAAAPRHAGRSEVGSV