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M. thermoresistible (build 8) TH_1694 (-)

annotation: ALANINE RACEMASE ALR
coordinates: 3272189 - 3273409
length: 407

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1694--100% (407)ALANINE RACEMASE ALR
M. thermoresistible (build 8)TH_2343-7e-0526.79% (209) methylmalonyl-CoA carboxyltransferase 12S subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3457calr1e-15972.92% (373) alanine racemase
M. gilvum PYR-GCKMflv_4934alr1e-15772.01% (368) alanine racemase
M. tuberculosis H37RvRv3423calr1e-15972.92% (373) alanine racemase
M. leprae Br4923MLBr_00375alr1e-15671.62% (370) alanine racemase
M. abscessus ATCC 19977MAB_3739calr1e-12959.70% (397) alanine racemase
M. marinum MMMAR_1119alr1e-16073.58% (371) alanine racemase, Alr
M. avium 104MAV_4372alr1e-15471.89% (370) alanine racemase
M. smegmatis MC2 155MSMEG_1575alr1e-15569.71% (383) alanine racemase
M. ulcerans Agy99MUL_0879alr1e-16073.32% (371) alanine racemase
M. vanbaalenii PYR-1Mvan_1484alr1e-15168.24% (381) alanine racemase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4934|M.gilvum_PYR-GCK          --------------------MTTT----ENRLMNTPSAVIDLDAIAHNVG
Mvan_1484|M.vanbaalenii_PYR-1       --------------------MTTTPTMTQKLPQALPTASIDLDAIAHNVA
MSMEG_1575|M.smegmatis_MC2_155      --------------------MQTTEPMTPPAPLASAQTVIDLGAIDHNVR
TH_1694|M.thermoresistible__bu      -----------------MGSDTTGHPAQRTVSSATAEAVVDLGAIAHNVR
MLBr_00375|M.leprae_Br4923          ----------------------MAVTPISLRPGVLAEAVVDLGAIDYNVR
MAV_4372|M.avium_104                ----------------------MAVTPISLTPGVLAEALVDLGAIEHNVR
Mb3457c|M.bovis_AF2122/97           MKRFWENVGKPNDTTDGRGTTSLAMTPISQTPGLLAEAMVDLGAIEHNVR
Rv3423c|M.tuberculosis_H37Rv        MKRFWENVGKPNDTTDGRGTTSLAMTPISQTPGLLAEAMVDLGAIEHNVR
MMAR_1119|M.marinum_M               ----------------------MTTTPISLTPGVLAEAVVDLGAIAHNVR
MUL_0879|M.ulcerans_Agy99           ----------------------MTTTPISLTPGVLAEAVVDLGAIAHNVR
MAB_3739c|M.abscessus_ATCC_199      -------------MGPVSTTSTTTDGLPPSTGATTAQAVIDLGAIAHNVK
                                                                       . : :**.** :** 

Mflv_4934|M.gilvum_PYR-GCK          VLRDRAGRAAVMAVVKADGYGHGATAVARAALAAGATNLGVATLDEALSL
Mvan_1484|M.vanbaalenii_PYR-1       VLREHAGPAAVMAVVKADGYGHGATQVARAALAAGAAELGVATVGEALAL
MSMEG_1575|M.smegmatis_MC2_155      VLRELAGSADVMAVVKADAYGHGALPVARTALAAGAAALGVATIPEALAL
TH_1694|M.thermoresistible__bu      VVRERAGSAQVMAVVKADGYGHGATAVARTALAAGATELGVATVGEALAL
MLBr_00375|M.leprae_Br4923          VLREHAGMAQLMVVLKADAYGHGATQVALAALAAGAAELGVATVDEALAL
MAV_4372|M.avium_104                LLCEQARGAQVMAVVKADGYGHGAVQTARAALAAGAAELGVATVDEALAL
Mb3457c|M.bovis_AF2122/97           VLREHAGHAQLMAVVKADGYGHGATRVAQTALGAGAAELGVATVDEALAL
Rv3423c|M.tuberculosis_H37Rv        VLREHAGHAQLMAVVKADGYGHGATRVAQTALGAGAAELGVATVDEALAL
MMAR_1119|M.marinum_M               LLRERAGSAQVMAVVKADGYGHGATAVARTALAAGAVELGVASVDEALTL
MUL_0879|M.ulcerans_Agy99           LLRERAGSAQVMAVVKADGYGHGATAVARTALAAGAVELGVASVDEALTL
MAB_3739c|M.abscessus_ATCC_199      LLREHAGTARLMTVVKADGYGHGAVRVARAALAAGADELGVTSIAEALQI
                                    :: : *  * :*.*:***.*****  .* :**.***  ***::: *** :

Mflv_4934|M.gilvum_PYR-GCK          RRDGVTAPVLSWLHPPGTDFTPAVQADIEVALSSRRQLDDLLRAVARTGR
Mvan_1484|M.vanbaalenii_PYR-1       RRDGVTARVLAWLHPPGTDFAPALLADVDVAVSSLRQFTDLLDAAGRTGR
MSMEG_1575|M.smegmatis_MC2_155      REGGITAPVLAWLHPPGTDFAPAIAADVEVAVSSRRQLEQVTAAAAEVGR
TH_1694|M.thermoresistible__bu      RRDGVTAPVLSWLNPPGTDYAPALRAQIEVAVSSRRQLDEVLDAARRTGV
MLBr_00375|M.leprae_Br4923          RADGISAPVLAWLHPPGIDFGPALLADVQIAVSSVRQLDELLDAVRRTGR
MAV_4372|M.avium_104                RAAGISAPVLAWLHPPGIDFRPALLAGVQIGLSSQRQLDELLTAVRDTGR
Mb3457c|M.bovis_AF2122/97           RADGITAPVLAWLHPPGIDFGPALLADVQVAVSSLRQLDELLHAVRRTGR
Rv3423c|M.tuberculosis_H37Rv        RADGITAPVLAWLHPPGIDFGPALLADVQVAVSSLRQLDELLHAVRRTGR
MMAR_1119|M.marinum_M               RADGITAPVLAWLHAPGMDFGPALAADVQIAISSIRQLDEVLDAARRTGT
MUL_0879|M.ulcerans_Agy99           RADGITAPVLAWLHAPGMDFGPALAADVQIAISSIRQLDEALDAARRTGT
MAB_3739c|M.abscessus_ATCC_199      RAAGLDAPLLAWLHAPGADYAAALHADVEVAVSSLGQLGELLAAARSTGR
                                    *  *: * :*:**:.** *: .*: * :::.:**  *: :   *.  .* 

Mflv_4934|M.gilvum_PYR-GCK          TATVTVKADTGLSRNGVSPADHPGLVSALARAQTDGAVTVHGLMSHLAHG
Mvan_1484|M.vanbaalenii_PYR-1       TADVTVKADTGLSRNGVGEADYPALVDALRRAASDGAVRVRGLMSHLAHG
MSMEG_1575|M.smegmatis_MC2_155      TATVTVKVDTGLSRNGVGAADYPEVLDVLRRAQADGAIRVRGLMSHLVHG
TH_1694|M.thermoresistible__bu      TATLSVKVDTGLNRNGVSRAEYPEVLAAVRRAQAEGAIRLRAVMSHLVAA
MLBr_00375|M.leprae_Br4923          TATVTVKADTGLNRNGVVTDQYPAMLTALQRAVVEDAVRLRGLMSHLVYA
MAV_4372|M.avium_104                TATVTVKVDTGLNRNGVPPAQYPSMLTALRRAVAEQAIVPRGLMSHMVYA
Mb3457c|M.bovis_AF2122/97           TATVTVKVDTGLNRNGVGPAQFPAMLTALRQAMAEDAVRLRGLMSHMVYA
Rv3423c|M.tuberculosis_H37Rv        TATVTVKVDTGLNRNGVGPAQFPAMLTALRQAMAEDAVRLRGLMSHMVYA
MMAR_1119|M.marinum_M               TATVTVKIDTGLNRNGVAPALYPEMVTRLRQAVAEDAIRLRGLMTHMVHA
MUL_0879|M.ulcerans_Agy99           TATVTVKIDTGLNRNGVAPALYPEMVTRLRQAVAEDAIRLRGLMTHMVHA
MAB_3739c|M.abscessus_ATCC_199      QAITSIKVDTGLNRNGVPAGYTRDLFEALAKAQAEESIRLRGIMSHFAYA
                                     *  ::* ****.****       :.  : :*  : ::  :.:*:*:. .

Mflv_4934|M.gilvum_PYR-GCK          DVPDHPFNDEQARRLTEMASEARSAGVAYDVVHLCNSPAALTRPDLAFDM
Mvan_1484|M.vanbaalenii_PYR-1       DDPEHPFNDVQARRLTEMAKLAGARGVSYDVVHLSNSPAALTRPDLAFDM
MSMEG_1575|M.smegmatis_MC2_155      DDPENPFNGLQGQRLADMRVYAREHGVDYEVAHLCNSPAAMTRPDLAFEM
TH_1694|M.thermoresistible__bu      DEPDNPVTDIQRQRFSEMRAQARDAGLRFEIAHLCNSAGTMSRPDLAFDM
MLBr_00375|M.leprae_Br4923          DQPDNPSNDVQGKRFAALLAQAHEQGLRFEVAHLSNSSATMSRPDLAYDL
MAV_4372|M.avium_104                DQPANPVNDVQAQRFTDMLAQAREQGVRFEVAHLSNSSATMSRPDLAFDM
Mb3457c|M.bovis_AF2122/97           DKPDDSINDVQAQRFTAFLAQAREQGVRFEVAHLSNSSATMARPDLTFDL
Rv3423c|M.tuberculosis_H37Rv        DKPDDSINDVQAQRFTAFLAQAREQGVRFEVAHLSNSSATMARPDLTFDL
MMAR_1119|M.marinum_M               DAPEKPINDIQSQRFKQMFDHARDQGVRFEVAHLSNSSATMARPDLTLDL
MUL_0879|M.ulcerans_Agy99           DAPEKPINDIQSQRFKQMLDHARDQGVRFEVAHLSNSSATMARPDLTLDL
MAB_3739c|M.abscessus_ATCC_199      DQPGHPTVDMQIGRFNEALELARGFGLRYELAHLSNSAATLTRPDARYDM
                                    * * ..  . *  *:      *   *: :::.**.**..:::***   ::

Mflv_4934|M.gilvum_PYR-GCK          VRPGIAVYGQTPI-------PERG--DMGLRPAMTVKCPVALVRSVRAGD
Mvan_1484|M.vanbaalenii_PYR-1       VRPGIAVYGQTPI-------PQRG--DFGLRPAMTVKCPVSAVRPVRAGD
MSMEG_1575|M.smegmatis_MC2_155      VRPGISLYGLSPI-------PERG--DMGLRPAMTLKCPVALVRSVHAGD
TH_1694|M.thermoresistible__bu      VRAGIAVYGLSPI-------PQRG--DLGLKPAMTLKCPVALVKQVRAGE
MLBr_00375|M.leprae_Br4923          VRPGIAVYGLSPV-------PSRG--DMGLIPAMTVKCAVAMVKSIRAGE
MAV_4372|M.avium_104                VRPGIAVYGLSPV-------PELG--DMGLVPAMTVKCTVALVKSIRAGE
Mb3457c|M.bovis_AF2122/97           VRPGIAVYGLSPV-------PALG--DMGLVPAMTVKCAVALVKSIRAGE
Rv3423c|M.tuberculosis_H37Rv        VRPGIAVYGLSPV-------PALG--DMGLVPAMTVKCAVALVKSIRAGE
MMAR_1119|M.marinum_M               VRPGIAVYGLSPV-------PRLG--DMGLVPAMTVKCAVALVKSVSAGE
MUL_0879|M.ulcerans_Agy99           VRPGIAVYGLSPV-------PRLG--DMGLVPAMTVKCAVALVKSVSAGE
MAB_3739c|M.abscessus_ATCC_199      VRPGIAVYGINPLGAAESATSNRGRTSFDLIPAMSLTCAVSSVKPVSAGE
                                    **.**::** .*:       .  *  .:.* ***::.*.*: *: : **:

Mflv_4934|M.gilvum_PYR-GCK          GVSYGHTWLAPRDTTLALIPAGYADGVFRALSNRFEVTINGRRYPNVGRV
Mvan_1484|M.vanbaalenii_PYR-1       AVSYGHTWTAQTDTTLALVPAGYADGVFRALSNRFEVSINGRRYPNVGRI
MSMEG_1575|M.smegmatis_MC2_155      GVSYGHRWVADRDTTLGLLPIGYADGVYRALSGRIDVLIKGRRRRAVGRI
TH_1694|M.thermoresistible__bu      GVSYGHAWTADRDTTIALLPIGYADGVFRPLSNRFEVLINGRRHRNVGRV
MLBr_00375|M.leprae_Br4923          GVSYGHDWIAQHDTNLALLPVGYADGVFRSLGGRLDVLINGKRRPGVGRI
MAV_4372|M.avium_104                SVSYGHTWTAQRDTNLALLPVGYADGIFRSLGGRLQVSINGRRRPGVGRI
Mb3457c|M.bovis_AF2122/97           GVSYGHTWIAPRDTNLALLPIGYADGVFRSLGGRLEVLINGRRCPGVGRI
Rv3423c|M.tuberculosis_H37Rv        GVSYGHTWIAPRDTNLALLPIGYADGVFRSLGGRLEVLINGRRCPGVGRI
MMAR_1119|M.marinum_M               GVSYGHTWIAPHDTNVALLPIGYADGVFRSLGGRLEVLINGKRRPGVGRV
MUL_0879|M.ulcerans_Agy99           GVSYGHTWIAPHDTNVALLPIGYADGVFRSLGGRLEVLINGKRRPGVGRV
MAB_3739c|M.abscessus_ATCC_199      GVSYGHVWTAPRDTNAALIGIGYADGVVRALGNRFEVAIGGRRYPNIGRV
                                    .***** * *  **. .*:  *****: *.*..*::* * *:*   :**:

Mflv_4934|M.gilvum_PYR-GCK          CMDQFVVDLGPGPVDVAEGDDAILFGPGDDGEPTAQDWADLLGTINYEVV
Mvan_1484|M.vanbaalenii_PYR-1       CMDQFVVDLGPGPVDVAEGDDAILFGPGTDGEPTAQDWAELLDTINYEVV
MSMEG_1575|M.smegmatis_MC2_155      CMDQFVVDLGPDADDVAVGDDAILFGPGANGEPTAQDWAELLDTIHYEVV
TH_1694|M.thermoresistible__bu      CMDQFVVDLGPGPVDVTEGDEAILFGPGDSGEPSAQDWADLLDTIHYEVV
MLBr_00375|M.leprae_Br4923          CMDQFVVDLGPGPIDVAEGDEAILFGPGARGEPTAQDWADLLGTIHYEVV
MAV_4372|M.avium_104                CMDQFVVDLGPGRPDVAEGDEAILFGPGSNGEPTAQDWADLLGTIHYEVV
Mb3457c|M.bovis_AF2122/97           CMDQFMVDLGPGPLDVAEGDEAILFGPGIRGEPTAQDWADLVGTIHYEVV
Rv3423c|M.tuberculosis_H37Rv        CMDQFMVDLGPGPLDVAEGDEAILFGPGIRGEPTAQDWADLVGTIHYEVV
MMAR_1119|M.marinum_M               CMDQFLVDLGPGPLDVAEGDEAILFGPGTRGEPTAQDWADLVGTIHYEVV
MUL_0879|M.ulcerans_Agy99           CMDQFLVDLGPGPLDVAEGDEAILFGPGTRGEPTAQDWADLVGTIHYEVV
MAB_3739c|M.abscessus_ATCC_199      CMDQFVVDLGDNDAGVQAGDVATLFGPGTGGEPTAQDWAELLDTIAYEVV
                                    *****:**** .  .*  ** * *****  ***:*****:*:.** ****

Mflv_4934|M.gilvum_PYR-GCK          TSPRGRIVRGYVGGAQ----------------
Mvan_1484|M.vanbaalenii_PYR-1       TSPRGRIVRTYVGGKGGPQ-------------
MSMEG_1575|M.smegmatis_MC2_155      TSPRGRVTRTYLPAGQQD--------------
TH_1694|M.thermoresistible__bu      TSPRGRVVRTYREADARAAAPRHAGRSEVGSV
MLBr_00375|M.leprae_Br4923          TSLRGRITRTYREAQTVDR-------------
MAV_4372|M.avium_104                TSPRGRITRTYREAHTVES-------------
Mb3457c|M.bovis_AF2122/97           TSPRGRITRTYREAENR---------------
Rv3423c|M.tuberculosis_H37Rv        TSPRGRITRTYREAENR---------------
MMAR_1119|M.marinum_M               TSPRGRITRVYREAETVER-------------
MUL_0879|M.ulcerans_Agy99           TSPRGRITRVYREAETVER-------------
MAB_3739c|M.abscessus_ATCC_199      TGPRGRVVRTYRDSRAVE--------------
                                    *. ***:.* *  .