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TAPGIAPIDDAVFDAAVRDLHDRPLDWRFKGVPADWWGRTEAQIIAAGSAVPVGVGAGPHCVLRADALTH NLHTMARWCAARGMELAPHGKTHMSPQLAERQLAGGACAITVATVAQAAVYRAFGVRSLLLANELVDAAG LRWVSAELDRDPDLRFVCWVDSVRGVELMTAALDGARRPIDVCVEVGIPGGRFGCRTAEAADDVARAAAA SPRLRLVGVAGYEAAVAQSLDDDALAVVTAHLAEVRATVIRLAALFEDDDVVVTAGGSTYFDAVADALSD WPGGARVRPILRSGCYLAHDHGLYARTSPLTRGRPDGFRPALEIRAQVLSRPEPDLAIVGMGRRDVSFDQ GMPVPLDDAAGAVEKLNDQHAYLRVTSGDVEVGDWLRFGISHPCTTFDKWRLIPVLDADDRVVDLVHTFF *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1427 | - | - | 100% (421) | hypothetical protein Mflv_1427 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1253c | - | 2e-11 | 25.61% (367) | hypothetical protein MAB_1253c |
| M. marinum M | MMAR_2646 | - | 2e-07 | 29.73% (185) | hypothetical protein MMAR_2646 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6095 | - | 1e-141 | 63.55% (406) | D-amino acid deaminase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3122 | - | 2e-07 | 29.73% (185) | hypothetical protein MUL_3122 |
| M. vanbaalenii PYR-1 | Mvan_5361 | - | 1e-176 | 72.77% (426) | hypothetical protein Mvan_5361 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1427|M.gilvum_PYR-GCK MTAPGIAPIDDAVFDAAVRDLHDRPLDWRFKGVPADWWGRTEAQIIAAGS
Mvan_5361|M.vanbaalenii_PYR-1 MTVPVNAPIDMAVYRTGVRALSDQPLDWSFKGIPARWWGRTPAQIVAQRP
MSMEG_6095|M.smegmatis_MC2_155 MNAPRNAPR--------LAALADAPVDWRFKGLPASWAGRTPADIVGARV
MMAR_2646|M.marinum_M --------------------MHEVGREQRSDEMAR----LDEQNRLQRYE
MUL_3122|M.ulcerans_Agy99 --------------------MHEVGREQRSDEMAR----LDEQNRLQRYE
MAB_1253c|M.abscessus_ATCC_199 --------------------MSDTTAHSGLDGLDT---------------
: : . . :
Mflv_1427|M.gilvum_PYR-GCK AVPVGVG-AGPHCVLRADALTHNLHTMARWCAARGMELAPHGKTHMSPQL
Mvan_5361|M.vanbaalenii_PYR-1 ELFGAGA-IGPVCVLRDEALTHNLQTMAGWCRDRGVELAPHGKTHMSPQL
MSMEG_6095|M.smegmatis_MC2_155 GLFDGDGPLGPVCVLSESAVAHNLATMARWCAERGVELAPHGKTHMAPQL
MMAR_2646|M.marinum_M EAFADQD--APFAFVDLDAMWSNAGQMLSRAGDKPIRVASKSLRCRPLQR
MUL_3122|M.ulcerans_Agy99 EAFADQD--APFAFVDLDAMWSNAGQMLSRAGDKPIRVASKSLRCRPLQR
MAB_1253c|M.abscessus_ATCC_199 ----------PFLAVDLAVMDRNIERLAGRLRGTGIRLRPHAKSHKCIEI
* : .: * : :.: .:. :
Mflv_1427|M.gilvum_PYR-GCK AERQLAGGACAITVATVAQAAVYRAFGVRSLLLANELVDAAGLRWVSAEL
Mvan_5361|M.vanbaalenii_PYR-1 AARQLAAGACAVTVATIGQAAVYRAFGVRSLVLANELVDGAGLRWLAAEL
MSMEG_6095|M.smegmatis_MC2_155 LARQFEAGACAVTAATVSQVRVFRAFGFDRFVIANEVTDPAGLAWLAHEL
MMAR_2646|M.marinum_M EILDSNPRFEGLMTFTLAETLWLAGQGFDNLLLAYPTTDRTGLRELGELT
MUL_3122|M.ulcerans_Agy99 EILDSNPRFEGLMTFTLAETLWLAGQGFDNLLLAYPTTDRTGLRALGELT
MAB_1253c|M.abscessus_ATCC_199 ARRQIDSGAIGLTVATVGEAEVFAEAGFIDLFIAYPLWVTAQKARRLRQV
: .: . *:.:. *. :.:* :
Mflv_1427|M.gilvum_PYR-GCK DRDPDLRFVCWVDSVRGVELMTAAL--DGARRPIDVCVEVGIPGGRFG--
Mvan_5361|M.vanbaalenii_PYR-1 DRDPGLRFVCWVDSVRGVELMSDAL--AGARRRVDVCVEVGMPHGRTG--
MSMEG_6095|M.smegmatis_MC2_155 DADPGFGVVCWVDSVAGAELMTAALRRSGARRRLDVCVEVGMDGGRTG--
MMAR_2646|M.marinum_M AENPARAPIVMVDSVEHLDLIDRAT-----DRPVRLCLDLDAGYWRAGGR
MUL_3122|M.ulcerans_Agy99 AENPARAPIAMVDSVEHLDLIDRAT-----DRPVRLCLDLDAGYWRAGGR
MAB_1253c|M.abscessus_ATCC_199 ASRAALR--VAVDSAAGAQQLAEHLG----DLPITVVIEVDSGHHRTG--
. ***. : : : : :::. * *
Mflv_1427|M.gilvum_PYR-GCK ---------CRTAEAADDVARAAAASPRLRLVGVAGYEAAVAQSLDDDAL
Mvan_5361|M.vanbaalenii_PYR-1 ---------CRSEADTDEVARAVVNSPRLRLVGVAGYEAALSQTLTAEAV
MSMEG_6095|M.smegmatis_MC2_155 ---------CRTTAEVDAVARAVVDSPRLRLVGVSGYEAATGQDVTQEAI
MMAR_2646|M.marinum_M VKVGPKRSPLHTPEQARELALEIARRPRLRLVALMSYEGHIAG--FGDQV
MUL_3122|M.ulcerans_Agy99 VKVGPKRSPLHTPERARELALEIARRPRLRLVALMSYEGHIAG--FGDQV
MAB_1253c|M.abscessus_ATCC_199 -----------VAPDQAGPVAAAARSAGLNVVGIFTFPGHGYTPGHRAEV
. . . *.:*.: : . :
Mflv_1427|M.gilvum_PYR-GCK AVVTAHLAEVRATVIRLAALFEDDDVVVTAGGSTYFDAVADALS-DWPG-
Mvan_5361|M.vanbaalenii_PYR-1 AAVTAHLAQLRATVIRLSALFETDDVLVTAGGSTYFDDVAEALT-GWPSG
MSMEG_6095|M.smegmatis_MC2_155 DGVRAYLDGLRAAVLRLTAQFETDEVIVTAGGSTYFDHVADVLTGDWPT-
MMAR_2646|M.marinum_M AGKFAQNAIVRWMQRESFAELRER----RARAVELVSEVAELEIVNAGG-
MUL_3122|M.ulcerans_Agy99 AGKFAQNAIVRWMQRESFAELRER----RARAVELVSEVAELKIVNAGG-
MAB_1253c|M.abscessus_ATCC_199 AAQESHALDTAAASLR------------AQGIDPSVRSGGSTPTVGAAD-
: . . .. .
Mflv_1427|M.gilvum_PYR-GCK --GARVRPILRSGCYLAHDHGLYARTSPLTRGRPDGFRPALEIRAQVLSR
Mvan_5361|M.vanbaalenii_PYR-1 LSGLSVRTVLRSGCYLTHDHGLYANTSPLTRGGRTGLRPALEVHAQVVSR
MSMEG_6095|M.smegmatis_MC2_155 --GSRVRTILRSGCYLTHDDGLYARTSPLS------LRAALRVWGQVVSR
MMAR_2646|M.marinum_M -TGDLQLVAHESAVTEATAGSGFYAPTLFDSYSAFSLQPAAMFALPICRR
MUL_3122|M.ulcerans_Agy99 -TGDLQLVAHESAVTEATAGSGFYAPTLFDSYSAFSLQPAAMFALPICRR
MAB_1253c|M.abscessus_ATCC_199 ---DTVLTEVRPGVYPFNDAQQLELD--VCTLDDIALSAVTTVVHARGRT
... . : .. .
Mflv_1427|M.gilvum_PYR-GCK PEPDLAIVGMG---RRDVSFDQGMPVPLDDAAGAVEKLN---DQHAYLRV
Mvan_5361|M.vanbaalenii_PYR-1 PEPDLAILTMG---RRDVPFDQGLPVALAPAAGTVTKLN---DQHAYLEL
MSMEG_6095|M.smegmatis_MC2_155 PEPRLALVAMG---RRDVSFDQGMPTPLGLPGGVVDKLN---DQHAFVRL
MMAR_2646|M.marinum_M PGAKTVTALGGGYLASGVGAKDRMPSPYLPSGLKLDPMEGTGEVQTPLSG
MUL_3122|M.ulcerans_Agy99 PGAKTVTALGGGYLASGVGAKDRMPSPYLPSGLKLDPLEGTGEVQTPLSG
MAB_1253c|M.abscessus_ATCC_199 AVVDAGSKILG---ADRPGWATGFGRVIDEPDARIVALS----EHHATIE
. * : . : :. :
Mflv_1427|M.gilvum_PYR-GCK TSG-DVEVGDWLRFGISHP---CTTFDKWRLIP---VLDADDRVVDLVHT
Mvan_5361|M.vanbaalenii_PYR-1 GPGGAAGVGQWLRFGISHP---CTLFDKWRLLP---VLDADDRVVDLIRT
MSMEG_6095|M.smegmatis_MC2_155 GPHDTPAVGAWLEFGISHP---CTTFDKWQLIP---VLDDDGIVVDLVRT
MMAR_2646|M.marinum_M RAARRLKVGDKVYFRHTKAGELCERFDRLYLVRGAQVVDVVPTYRGEGRT
MUL_3122|M.ulcerans_Agy99 RAARRLKVGDKVYFRHTKAGELCERFDRLYLVRGAQVVDVVPTYRGEGRT
MAB_1253c|M.abscessus_ATCC_199 FPGAAPPPGTRLRVAPNHLCNAVNLVDSLVIDAADGVRHWAVAARGANT-
. * : . .: .* : * . .
Mflv_1427|M.gilvum_PYR-GCK FF
Mvan_5361|M.vanbaalenii_PYR-1 FF
MSMEG_6095|M.smegmatis_MC2_155 FF
MMAR_2646|M.marinum_M FL
MUL_3122|M.ulcerans_Agy99 FL
MAB_1253c|M.abscessus_ATCC_199 --