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MDTDTGAGSPASEGSADAADTAPLPVLNALPGMLSDPGPFAPSEQDFGQPPFVEQPASPDPYWSAPAAPT PQFAGASTPQPIGEKPWGSGASASTVDFASWADKGPERSKRPLIIGGAVLAAVVLVGGVIAIFASGGGDD APTEPTAAPPTTTVSSRDTDAETRLLSMLPAGYAASACKAVEPANEAVAQVKCGRSDDPDGPIEASYSLV KDKSALAAGLSRLTKRNAVVVCPGRIQSPGPWRRNATPDQVSGTVFCGTNQGHPVVAWTDEERLLLSETR SGATGPTLDQLYAWWSSHS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1025 | - | - | 100% (299) | hypothetical protein MAB_1025 |
| M. abscessus ATCC 19977 | MAB_0652 | - | 3e-06 | 26.27% (118) | hypothetical protein MAB_0652 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1514 | - | 6e-45 | 47.18% (195) | hypothetical protein Mflv_1514 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4169 | pknH_1 | 2e-35 | 33.66% (309) | transmembrane serine/threonine-protein kinase H, PknH_1 |
| M. avium 104 | MAV_4742 | - | 1e-15 | 30.82% (159) | hypothetical protein MAV_4742 |
| M. smegmatis MC2 155 | MSMEG_2961 | secD | 9e-06 | 35.71% (126) | preprotein translocase subunit SecD |
| M. thermoresistible (build 8) | TH_1441 | - | 9e-50 | 43.28% (238) | PROBABLE ATP-DEPENDENT DNA HELICASE |
| M. ulcerans Agy99 | MUL_3375 | pknH_2 | 5e-34 | 31.63% (294) | transmembrane serine/threonine-protein kinase H PknH_2 |
| M. vanbaalenii PYR-1 | Mvan_5242 | - | 9e-51 | 46.85% (222) | hypothetical protein Mvan_5242 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4169|M.marinum_M --------------------------------------------------
MUL_3375|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu LSGAGRAGRIGAAVTARHSPADLAEALGLFPPTEEQAAVIAAPPGPLVVI
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4169|M.marinum_M --------------------------------------------------
MUL_3375|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu AGAGAGKTETMAARVVWLVANGYARPDQVLGLTFTRKAAGQLLRRVRSRL
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4169|M.marinum_M --------------------------------------------------
MUL_3375|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu ARLAGTGLVPANSAPDWTTESVTVSTYHAFAGTLLREHGLLLPVEPDTRL
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4169|M.marinum_M --------------------------------------------------
MUL_3375|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu IGETELWQLAYRVVCEHPGPLDTDKTPAAITAMVLRLAGQLAEHLVDTDQ
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4169|M.marinum_M --------------------------------------------------
MUL_3375|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu LRDTHVELERLVHTLPAGPYQRDRGPSQWLLNMLATQTERAALVPLIDAV
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4169|M.marinum_M --------------------------------------------------
MUL_3375|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu HRRMRAEKVMDFGMQMAAAARLASEHPQVGAALRQRFRVVLLDEYQDTGH
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4169|M.marinum_M --------------------------------------------------
MUL_3375|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu AQRIALSALFGGGVDDDLALTAVGDPIQSIYGWRGASATNLPRFATDFPH
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4169|M.marinum_M --------------------------------------------------
MUL_3375|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu SDGSPAPTLELRTSWRNPPRTLHLANAISAEARRRSVAVRALRPRPDAEP
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4169|M.marinum_M ------------------------MSEAP-SARAGSMFGPYRLIRPLGRG
MUL_3375|M.ulcerans_Agy99 ------------------------MSASARRSRVGTRFGPYYLKRQLGTG
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu GTIRCALLDDVQSEREWVAEQLAALYRHARDAGDTPPTAAVLVRRNADAA
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 -------------------MASSSAPVHPARYLTLFLVLLVGVYLLVFLT
MMAR_4169|M.marinum_M GMGQVYEAEHTVKGWAVAVKLMSETFSSDPVFRERMKREARITG------
MUL_3375|M.ulcerans_Agy99 GMGEVYEAVDTVRQRVVALKLMSESLSHDPVFRMRMQREARNAG------
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu PMAQALTARGVPVEVVGLAGLLAVPEVADVVAMLRLAADPTAGSAAVRIL
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 GDKKPEPKLGIDLQGGTRVTLTARTPDGSAPTRDALNQAQQIISARVDGL
MMAR_4169|M.marinum_M -----RLQEPHVVPIHDYGEIDGQMFLEMRLIEGTNLDSLLKRFGPLTPP
MUL_3375|M.ulcerans_Agy99 -----RLQEPHVVPIHDYGEIDGQLYLDMRLIERTHLALLLERFGPVTPP
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu TGPRWRLGARDLTALWRRAVELGTVEPPGARPDTDGVEQILAGIGPDADE
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 GVSGSEVVIDGDNLVITVPGNDGNEARNLGQTARLYIRPVIHAMAAQPPT
MMAR_4169|M.marinum_M -----------------------RAVAIITQIASALDAAHADEVMHRDVK
MUL_3375|M.ulcerans_Agy99 -----------------------WAVALVHQVASALDAAHAAGVMHRDVK
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu PCLADAICDPGDAAAYSEEGYRRITALAQELTALRAHLHHPLPDLIAEIR
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 E---------------------------DGQPPAGAPGAPGAPGGAPGAP
MMAR_4169|M.marinum_M PPNILITRDDFAYLVDFGIANAATDEKLTQMGTAVGTWKYMAPERFTNDR
MUL_3375|M.ulcerans_Agy99 PENILVTQDDFVYLVDFGIASAATDEKLTQIGSAVGTWRYMAPERFSDAE
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu RILGVDAEARAGQPVAAGWAGTENLDAFADVVAEFAVRPNATVPALLGYL
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 GLPGLPGLSGLPGMPGAPGAPGAPQEAPPGMPVPGEAPGGEAPAPPAGEQ
MMAR_4169|M.marinum_M VTHHADIYALACVLHESLTGSAPYQSNNAGLLISAHMMEPIPKPSAVHPE
MUL_3375|M.ulcerans_Agy99 VNQRADIYSLTCVLHECLTGTPPYRADSAGMLITAHLMAPIPRPSQLRPD
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu SAAMEVENGLAPADVTVATDRVQILTVHAAKGLEWEVVAVPHLSRRVFPS
MAB_1025|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 PAPQPRPYPLEPAPTPGEPTPAPAPEPAPGENPPAAPAPGADGDKADLAQ
MMAR_4169|M.marinum_M IPKAFDAVIARGMAKKPADRYASAGDLARAAHQALSTPDQNQAETILRRS
MUL_3375|M.ulcerans_Agy99 IPATFDAVIARGMAKRPEDRFASAGELAAAAHQALSAPHQAQEFRILKRG
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu TASPRTWLTDAGELPPLLRGDRATTSEHGVPVLDTADVNDRKALSDKIAE
MAB_1025|M.abscessus_ATCC_1997 ------MDTDTGAGSPASEGSADAADTAPLPVLN--------ALPGMLSD
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 RIATAKQWRQSTDPTMQILGLQVQANLCGEDDILAGNDDPNLPLITCSTD
MMAR_4169|M.marinum_M QQS-TLPGQVVEQPTLEHRREPRCGPANPQHSSGPMPAYSSEPIPRSGPS
MUL_3375|M.ulcerans_Agy99 EEAGGLHTDAAAEAGITFASPSTASPSAPTPVASTSQPDLRISGPLSIPS
Mflv_1514|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5242|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1441|M.thermoresistible__bu HKNRLAQRRTDEERRLLYVAVTRAEDTLLVSGHHWGATESKPRGPSEFLL
MAB_1025|M.abscessus_ATCC_1997 PG---------------------------------------PFAPSE---
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 GSTVYLLNKSIMSGEEIKNATSGLDQQQGQYVVDVEFKSGGAQTWADFTA
MMAR_4169|M.marinum_M GPTHPPSGPIGQPAWSPGAHPAAPAHSPVAPPPWDGGMSPGAAPRALAPQ
MUL_3375|M.ulcerans_Agy99 FPTSEANVPLFDASTSSWGDLTAAPPPQAPPAPLTPPTPPVPPTPPQPPK
Mflv_1514|M.gilvum_PYR-GCK ------------------MSSREPHPDDDDTGPLN-----VDRVGPPTD-
Mvan_5242|M.vanbaalenii_PYR-1 ------------------MSSHEPEPDDADTGPLH-----VSRLRTPLGE
TH_1441|M.thermoresistible__bu EIKDVIDRSAEAGDPCGTIDLWAPEPPDGTPNPLRDKAFEVLWPAPPXXX
MAB_1025|M.abscessus_ATCC_1997 ---------QDFGQPPFVEQPASPDPYWSAPAAPTPQFAGASTPQPIGEK
MAV_4742|M.avium_104 --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 ANVGTQTAFTLDSKVVSAPEIREAIPGGNTQITGQFTADSAKELANVLKY
MMAR_4169|M.marinum_M QLGGTPAWNPGVPQRPP---RARNPWAIVSGVAVAILVMILVAIVIWAAT
MUL_3375|M.ulcerans_Agy99 QTSDTSPSGPGPHFLAA---SLRNPWMLLG-AAALVALIVFAAQGIWLS-
Mflv_1514|M.gilvum_PYR-GCK ---DPRSRYDAPMSVNP-RPVHRNRTPIVPIAAAAAAVVGIGALAWIFW-
Mvan_5242|M.vanbaalenii_PYR-1 GPGDREPRYDAPLSVNP-RPVHRDRRPVVLVAAAAAALVGLGALAWVFW-
TH_1441|M.thermoresistible__bu PAGPPPPVSPRITTPSA-GGAQPNRRRLIAGVAGVAAVAVLGGLAFWLL-
MAB_1025|M.abscessus_ATCC_1997 PWGSGASASTVDFASWADKGPERSKRPLIIGGAVLAAVVLVGGVIAIFA-
MAV_4742|M.avium_104 -------------------MSYRNTALRLVSAAAFTGSLALAG-------
MSMEG_2961|M.smegmatis_MC2_155 GSLPLSFESSEAETVSATLGLSSLRAGLIAGAIGLAAVLLYSLLYYRVLG
:
MMAR_4169|M.marinum_M HDDNPQPTGQRTTSTTARTTTGSTATTTPAPSTTSRRPDAQTRLMGLLPS
MUL_3375|M.ulcerans_Agy99 ---------FRPKSESASTSPSTASPSAPSPAS----ADALARLLSTLPL
Mflv_1514|M.gilvum_PYR-GCK ------------PDAEGGQDTSADSAPVRQTES---QQATDARLQGLLPE
Mvan_5242|M.vanbaalenii_PYR-1 ------------PSS-GGEGHAGAPTTTTETES---REEAETRLLDMVPP
TH_1441|M.thermoresistible__bu ------------SPSGTDQADGARADDTAETTSPPRDTAAENRLLTMLPP
MAB_1025|M.abscessus_ATCC_1997 ------------SGGGDDAPTEPTAAPPTTTVSS-RDTDAETRLLSMLPA
MAV_4742|M.avium_104 ---------------------SAPALAEPNTGS----ASDMNTLAASLSK
MSMEG_2961|M.smegmatis_MC2_155 ---------LLVALSLVAAGAVVYAILVLLGRYIGYTLDLAGIAGLIIGI
. :
MMAR_4169|M.marinum_M GYPAGACTPETRPMPGAVASVKCKKNTDADGPTVAAYGLYANLSALKNAF
MUL_3375|M.ulcerans_Agy99 GYAPGTCR-AFLPAKDSLARVTCDKNVDPGGPSRGVYTLFGETATLRQYF
Mflv_1514|M.gilvum_PYR-GCK GYAPGACQ-PLEPSKGTLAQIDCVENDDVGGPLTATYTLVENDTARKAFF
Mvan_5242|M.vanbaalenii_PYR-1 GYAADACE-AVVPVNGALAQVSCDKNDDTGGPLTATYTLAKDGRALRELF
TH_1441|M.thermoresistible__bu GYSAGACG-PVPAPEGALAQVVCRENTDPGGPPTATYTLARDEAAMQRAF
MAB_1025|M.abscessus_ATCC_1997 GYAASACK-AVEPANEAVAQVKCGRSDDPDGPIEASYSLVKDKSALAAGL
MAV_4742|M.avium_104 GYGLNNCKPQELTESGELAELLCGQSPDPSGPGSGVYALFSNGTNLASAF
MSMEG_2961|M.smegmatis_MC2_155 GTTADSFVVFFERIKDEIREGRSFRSAVPRGWVRARKTIVSG-----NAV
* . : . .. * . : .
MMAR_4169|M.marinum_M TAFIGTFSILTCPDGKASPGTWWHTQDPNTVLGQVACGIYKGAEPQVMWS
MUL_3375|M.ulcerans_Agy99 DGLLRTDIMVDCPGEKKSP-TAWHHPDSPQVGGMIFCAIQEGS-PSVVWT
Mflv_1514|M.gilvum_PYR-GCK DDVTARLSVVDCPGNIQSPGPWRRNAAPDQPVGTLVCGFQESR-PTVAWT
Mvan_5242|M.vanbaalenii_PYR-1 DGVVNASAVVNCPGNIQSPGPWRRNATPEQTAGTLVCGFQQSR-PTVAWT
TH_1441|M.thermoresistible__bu DEIIAASATVNCPNFIQSPGPWRRNATPDRISGTLFCGIQQNE-PLVAWT
MAB_1025|M.abscessus_ATCC_1997 SRLTKRNAVVVCPGRIQSPGPWRRNATPDQVSGTVFCGTNQGH-PVVAWT
MAV_4742|M.avium_104 SSTIKDVSLANCGDAGQSPGTWKQNG---QTGGQIACGTYKNY-ATLTWT
MSMEG_2961|M.smegmatis_MC2_155 TFLAAAVLYVLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSPT
. . . . . :
MMAR_4169|M.marinum_M NERTLVFALVAAKPPGPNLDQLYDWWSSHS
MUL_3375|M.ulcerans_Agy99 NEAQLMISVVPGDPRGPNLEELYSWWKKHS
Mflv_1514|M.gilvum_PYR-GCK TDADLLISEVQSGPQGPNMVQLYTWWASHS
Mvan_5242|M.vanbaalenii_PYR-1 TDTDLMVSEVQSGPQGPNMVQLYTWWASHS
TH_1441|M.thermoresistible__bu DDANLVVSAVHSGPQGPTLDELYAWWTTHS
MAB_1025|M.abscessus_ATCC_1997 DEERLLLSETRSGATGPTLDQLYAWWSSHS
MAV_4742|M.avium_104 TDAKNVLGHLTAAN--SDVNALYQWWRTNG
MSMEG_2961|M.smegmatis_MC2_155 MAKPKLNGLGAVQQIARERREVSHATAGRG
: . : ..